An Evidence Based Practice: Systematic Review of the effectiveness of
therapeutic hypothermia on neonatal asphyxia.
Ibn-Sina nursing and
midwifery collage
Background
There was evidence showing the
association of using therapeutic
hypothermia with the reduction of
death or disability in infancy and
childhood, and is a safe procedure
to be applied in clinical practice.
However, around 40%-50% of
infants treated with hypothermia
still die or suffer from significant
neurological disability (Edwards et
al., 2010).
Many knowledge gaps remain
unclear. Controversies exist and no
international consensus has been
reached. Therefore, it is necessary
to refine current hypothermia
treatment protocols.
The aim
To determine the effectiveness
of therapeutic hypothermia on
neonatal asphyxia.
Methodology Results Conclusion
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auther Conclusion previous literature review
Study design
Systemic review of recent literature Rao, et Therapeutic hypothermia in showed that the application of
related to therapeutic hypothermia al., infants born at 34–35 weeks therapeutic hypothermia on
in patient at risk for neonatal (2017) gestational age appears feasible neonates with hypoxic-ischemic
asphyxia Laptook, Hypothermia initiated at 6 to 24 encephalopathy could reduce
Criteria for considering studies for et al., hours after birth may have their mortality, improve their
this review (2017) benefit but there is uncertainty neurological outcomes and
Types of studies
in its effectiveness decrease their chances of
We included all randomized, cohort
NICHD, safety and effectiveness developing major disabilities
and quasi‐randomized studies (2005) of Therapeutic hypothermia in
comparing the use of therapeutic when they survive. The
infant
hypothermia with standard care for innovation is transferable and
Azzopar Therapeutic hypothermia in
neonate at risk of HIE. feasible to implement in the
di et al., infant resulted in improved
Types of interventions 2009 neurologic outcomes in NICU in Hong Kong as
Therapeutic cooling (whole body or mentioned in the previous
survivors.
selective head cooling) initiated chapter. In the following
prior to six hours after birth versus Silveira, therapeutic hypothermia is
2015 effective in reducing neurologic chapters, detailed discussions
no cooling (standard care).
impairment, especially in full- will be made on the
Search methods for identification of
studies term or near-term newborns communication plan, the pilot
Related publication includes with moderate hypoxic-ischemic study and the evaluation plan in
Pubmed, Google scholar, Springer encephalopathy. order to implement the
database, including original studies. Maoulai TH supports its beneficial effect evidence-based practical
We conduct this search between 25 nine, et in newborns with HIE. guideline successfully.
of March 2019 to 20 of April 2019 al., 2016
Hakobya A good outcome was reported Acknowledgements
n , et al., in the majority of infants with
2019 perinatal asphyxia, To our supervisor Mrs. Jamela
Taleb