ANAESTHETICS AND PREOPERATIVE MEDICINES

Injectable medicines
ketamine Injection: 50 mg (as hydrochloride)/ mL in 10- mL vial.
Injection: 10 mg/ mL; 20 mg/ mL.

propofol* * Thiopental may be used as an alternative depending on

Local anaesthetics local availability and cost.

Injection: 0.25%; 0.5% (hydrochloride) in vial.

bupivacaine Injection for spinal anaesthesia: 0.5% (hydrochloride) in

Injection: 1%; 2%
4- mL ampoule (hydrochloride)
to be in vial.
mixed with 7.5% glucose solution.

Injection for spinal anaesthesia: 5% (hydrochloride) in

lidocaine
2- mL ampoule to be mixed with 7.5% glucose solution.
Dental cartridge: 2% (hydrochloride) + epinephrine 1:80
000.
Topical forms: 2% to 4% (hydrochloride).
lidocaine + epinephrine (adrenaline)
Injection: 1%; 2% (hydrochloride or sulfate) + epinephrine
Complementary List
1:200 000 in vial.
Injection: 30 mg (hydrochloride)/ mL in 1- mL ampoule.
ephedrine
(For
Preoperative medication and sedation foruse in spinal anaesthesia
short-term proceduresduring delivery, to prevent
hypotension).
atropine Injection: 1 mg (sulfate) in 1- mL ampoule.
Injection: 1 mg/ mL.

midazolam Oral liquid: 2 mg/ mL [c].

morphine Injection: 10 mg (sulfate or hydrochloride) in 1- mL ampoule.

Tablet: 7.5 mg; 15 mg.
MEDICINES FOR PAIN AND PALLIATIVE CARE
Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs)
Suppository: 50 mg to 150 mg.
acetylsalicylic acid
Tablet: 100 mg
200tomg/5
500 mg.
Oral liquid: mL.

ibuprofen a Tablet: 200 mg; 400 mg; 600 mg.

a Not in children less than 3 months.

 Oral liquid: 120 mg/5 mL; 125 mg/5 mL.

Suppository: 100 mg.

paracetamol* Tablet: 100 mg to 500 mg.

Opioid analgesics
* Not recommended for anti-inflammatory use due to lack
codeine Tablet: 30 mg (phosphate).
of proven benefit to that effect.
Transdermal patch: 12 micrograms/hr; 25 micrograms/hr;
50
fentanyl* micrograms/hr; 75 micrograms/hr; 100 micrograms/hr
Granules (slow-release; to mix with water): 20 mg –200
mg
*for the management of cancer pain
(morphine sulfate).

Injection: 10 mg (morphine hydrochloride or morphine

sulfate)

in 1- mL ampoule.

morphine* Oral liquid: 10 mg (morphine hydrochloride or

morphine sulfate)/5 mL.
Complementary list
Tablet (slow
Tablet: release):
5 mg; 10 10 mg–200mg (morphine
mg (as hydrochloride)
hydrochloride
or morphine sulfate).
Oral liquid: 5mg/ 5mL; 10mg/ 5mL (as hydrochloride)
methadone*
Tablet (immediate release): 10 mg (morphine sulfate).
Concentrate for oral liquid: 5 mg/ mL; 10mg/ mL (as
Medicines for other common symptoms in palliative care
hydrochloride)
amitriptyline *Alternatives
Tablet: 10 mg;limited
25 mg;to75
hydromorphone
mg. and oxycodone
Injection: 50 mg/ mL.of cancer pain.
*For the management
cyclizine [c]
Tablet: 50 4mg.
Injection: mg/ mL in 1- mL ampoule (as disodium
phosphate
salt).
dexamethasone
Oral liquid:
Injection: 2 mg/5
5 mg/ mL.mL.

Tablet:
Oral 2 mg2[c];
liquid: mg/54 mg.
mL.
diazepam
Rectal solution: 2.5 mg; 5 mg; 10 mg.
Capsule: 100 mg.
docusate sodium
Tablet: 5 mg; 10 mg.
Oral liquid: 50 mg/5 mL.
 Solid oral dosage form: 20 mg (as hydrochloride).
fluoxetine a
a >8 years. 5 mg in 1‐ mL ampoule.
Injection:

haloperidol Oral liquid: 2 mg/ mL.

hyoscine butylbromide Injection: 20 mg/ mL.

Solid oral dosage form: 0.5 mg; 2mg; 5 mg.
Injection: 400 micrograms/ mL; 600 micrograms/ mL.
hyoscine hydrobromide [c]
Transdermal patches:
Oral liquid: 3.1–3.7 g/51mL.
mg/72 hours.
lactulose [c]
loperamide Solid oral dosage form: 2 mg.
Injection: 5 mg (hydrochloride)/mL in 2‐mL ampoule.

metoclopramide Oral liquid: 5 mg/5 mL.

Injection: 1 mg/ mL; 5 mg/ mL.

Solid oral form: 10 mg (hydrochloride).

midazolam Solid oral dosage form: 7.5 mg; 15 mg.

Injection: 2 mg base/ mL in 2- mL ampoule (as

Oral liquid: 2mg/ mL [c].
hydrochloride).
ondansetron [c] a

Oral liquid: 4 mg base/5 mL.

senna Oral
Solidliquid: 7.5 mg/5
oral dosage mL.
form: Eq 4 mg base; Eq 8 mg base.
ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS
Injection:
a >1 month. 4 mg/ mL in 1- mL ampoule (as disodium
dexamethasone phosphate salt).
Injection: 1 mg (as hydrochloride or hydrogen tartrate) in 1-
epinephrine (adrenaline) mL
hydrocortisone Powder
ampoule.for injection: 100 mg (as sodium succinate) in vial.
Oral liquid: 1 mg/ mL.

loratadine * Tablet: 10 mg.

*There
Oral may be
liquid: a rolemL
5 mg/ for[c].
sedating antihistamines for limited
indications
prednisolone
(EMLc). 5 mg; 25 mg.
Tablet:
ANTICONVULSANTS/ANTIEPILEPTICS
Oral liquid: 100 mg/5 mL.

carbamazepine Tablet (chewable): 100 mg; 200 mg.

diazepam Gel or rectal solution: 5 mg/ mL in 0.5 mL; 2- mL; 4- mL

Tablet
tubes. (scored): 100 mg; 200 mg.
 Tablet: 25 mg; 50 mg; 100 mg; 200 mg.

Tablet (chewable, dispersible): 2 mg; 5 mg; 25 mg; 50

mg; 100 mg; 200 mg.
lamotrigine*

*as adjunctive
Parenteral therapy for 2treatment-resistant
formulation: mg/ mL in 1- mL ampoule; 4 mg/
lorazepam partial or generalized seizures.
mL
in 1- mL ampoule.
Injection: 0.5g/ mL in 2- mL ampoule (equivalent to 1 g in 2
mL;
50% weight/volume); 0.5g/ mL in
magnesium sulfate* 10- mL ampoule (equivalent to 5 g in 10 mL; 50%
weight/volume).
Solution for oromucosal administration: 5 mg/mL; 10
mg/mL
* For use in eclampsia and severe pre-eclampsia and not
for other convulsant disorders.

midazolam Ampoule*: 1 mg/ mL; 10 mg/mL

Injection: 200 mg/ mL (sodium).

*for buccal administration when solution for
oromucosal administration is not available
phenobarbital Oral liquid: 15 mg/5 mL.

Injection: 50 mg/ mL in 5- mL vial (sodium

Tablet:
salt). 15 mg to 100 mg.

Oral liquid: 25 mg to 30 mg/5

mL.*

phenytoin
valproic acid (sodium valproate)
Solid oral dosage form: 25 mg; 50 mg; 100 mg (sodium
salt).
Oral liquid: 200 mg/5 mL.
Tablet (chewable): 50
mg.
Tablet (crushable): 100 mg.

Complementary List
* The presence
Tablet of both 25
(enteric-coated): 200mg/5 mLmg
mg; 500 and 30 mg/5 mL
(sodium
strengths
Capsule: on
250
valproate). the
mg. same market would cause confusion in
prescribing and dispensing and should be avoided.
ethosuximide
Oral liquid:100
Injection: 250mg/
mg/5
mL mL.
in 4- mL ampoule; 100 mg/ mL in 10-
valproic acid (sodium mL
valproate)
ANTI-INFECTIVE MEDICINES ampoule.
Anthelminthics
Intestinal anthelminthics
albendazole Tablet (chewable): 400 mg.
ivermectin Tablet (scored): 3 mg.
levamisole Tablet: 50 mg; 150 mg (as hydrochloride).
mebendazole Tablet (chewable): 100 mg; 500 mg.
niclosamide Tablet (chewable): 500 mg.
praziquantel Tablet: 150 mg; 600 mg.
Oral liquid: 50 mg (as embonate or pamoate)/ mL.
pyrantel
Tablet (chewable): 250 mg (as embonate or pamoate).
Antifilarials
albendazole Tablet (chewable): 400 mg.
diethylcarbamazine Tablet: 50 mg; 100 mg (dihydrogen citrate).
ivermectin Tablet (scored): 3 mg.
Antischistosomals and other antitrematode medicines
praziquantel Tablet: 600 mg.
triclabendazole Tablet: 250 mg.

Antibacterials Other antibacterials

amoxicillin cefotaxime* amikacin gentamicin
amoxicillin + clavulanic ceftriaxone* azithromycin* metronidazole
acid
ampicillin cloxacillin chloramphenicol nitrofurantoin
benzathine phenoxymethylpenicilli ciprofloxacin* spectinomycin (EML only)
benzylpenicillin n
piperacillin + clarithromycin* sulfamethoxazole +
cefalexin tazobactam*
procaine benzyl clindamycin trimethoprim
vancomycin (oral)*
cefazolin penicillin *
meropenem doxycycline vancomycin (parenteral)*
cefixime*
Powder for oral liquid: 125 mg (as trihydrate)/5 mL; 250 mg (as
trihydrate)/5
mL [c].

Solid
FIRSToral dosage form: 250 mg; 500 mg (asSECOND
CHOICE trihydrate).
CHOICE

Powder for injection:

- community 250 mg; 500 mg; 1 g (as
acquired pneumonia sodium)
- acute in vial.
bacterial meningitis
(mild to moderate)
- community acquired pneumonia (severe)
[c]
- complicated severe acute malnutrition [c]
amoxicillin
- exacerbations of COPD
- lower urinary tract infections
- otitis media
Oral liquid: 125 mg amoxicillin + 31.25 mg clavulanic acid/5 mL
- pharyngitis
AND 250 mg amoxicillin + 62.5 mg clavulanic acid/5 mL [c].
- sepsis in neonates and children [c]
amoxicillin + clavulanic acid
Tablet:
- sinusitis500 mg (as trihydrate) + 125 mg (as potassium salt).
- uncomplicated severe acute malnutrition
[c]
Powder for injection: 500 mg (as sodium) + 100 mg (as
potassium salt); 1000 mg (as sodium) + 200 mg (as potassium salt)
 Powder for injection: 900 mg benzylpenicillin (= 1.2 million IU) in 5-
mL vial
benzathine benzylpenicillin
FIRST g benzylpenicillin (= 2.4 million IU)SECOND
CHOICE
[c]; 1.44 in 5- mL CHOICE
vial.

- syphilis
Powder for injection: 600 mg (= 1 million IU); 3 g (= 5 million IU)
(sodium or
FIRST CHOICE
potassium salt) in vial. SECOND CHOICE
- acute bacterial
benzylpenicillin -community acquired pneumonia (severe) meningitis[c]
[c]
- complicated severe acute malnutrition [c]
Powder
- sepsis infor reconstitution
neonates with
and children [c]water: 125 mg/5 mL;
250 mg/5 mL (anhydrous).
- syphilis

Solid
FIRSToral dosage form: 250 mg (as monohydrate).
CHOICE SECOND CHOICE

cefalexin - exacerbations of COPD

- pharyngitis
Powder for injection: 1 g (as sodium salt) in- skin
vial.and soft tissue
infections
* also indicated for surgical prophylaxis.

FIRST CHOICE SECOND CHOICE

a >1 month.
cefazolin* a
- bone and joint infections
Powder for oral liquid: 250 mg (as potassium salt)/5 mL.

Tablet: 250 mg (as potassium salt).

FIRST CHOICE SECOND CHOICE

phenoxymethylpenicillin - community acquired pneumonia

(mild to moderate)
- pharyngitis
Powder for injection: 2 g (as sodium salt) + 250 mg (as sodium
salt); 4 g (as sodium salt) + 500 mg (as sodium salt) in vial
FIRST CHOICE SECOND CHOICE

piperacillin + tazobactam
- complicated intraabdominal infections
(severe)
- high-risk febrile neutropenia
- hospital acquired pneumonia
 Powder for injection: 1 g (=1 million IU); 3 g (=3 million IU) in vial.

* Procaine benzylpenicillin is not recommended as first-line

treatment for neonatal sepsis except in settings with high neonatal
mortality, when given by trained health workers
FIRST CHOICE in cases
SECOND where
CHOICE
hospital care is not achievable.
procaine benzylpenicillin*
- syphilis [c] - syphilis

Complementary List
ceftazidime
Powder for injection: 250 mg or 1 g (as pentahydrate) in vial.

Powder for injection: 500 mg (as trihydrate); 1 g (as trihydrate) in vial

a >3 months.

*imipenem
FIRST + cilastatin is an alternativeSECOND
CHOICE except for acute bacterial
CHOICE
meningitis where meropenem is preferred.
meropenem* a
- acute bacterial meningitis in
neonates [c]
- complicated intraabdominal
Complementary List – RESERVE GROUP infections

aztreonam Powder for injection: 1(severe)

g; 2 g in vial
fifth generation cephalosporins - high-risk febrile neutropenia

(with or without beta-lactamase Powder for injection: 400 mg; 600 mg (as fosamil) in vial
inhibitor)
fourth generation cephalosporins

e.g, ceftaroline
(with or without beta-lactamase Powder for injection: 500 mg; 1g; 2g (as hydrochloride)
inhibitor) in vial
Other antibacterials
Injection: 250 mg (as sulfate)/mL in 2- mL vial
e.g., cefepime
FIRST CHOICE SECOND CHOICE

amikacin -pyelonephritis or prostatitis (severe) - high-risk febrile neutropenia

Capsule: 250 mg; 500 mg (anhydrous). - sepsis in neonates and

children [c]

Oral liquid: 200 mg/5 mL.

FIRST CHOICE SECOND CHOICE

azithromycin* * also listed for single-dose treatment of trachoma and yaws.

- Chlamydia trachomatis - acute invasive bacterial

- cholera [c] diarrhoea /

- Neisseria gonorrhoeae dysentery

 Capsule: 250 mg.

Oily suspension for injection*: 0.5 g (as sodium succinate)/ mL in 2-

mL
ampoule.

* Only for the presumptive treatment of epidemic meningitis in

children older than 2 years and in adults.
FIRST CHOICE SECOND CHOICE
chloramphenicol
Oral liquid: 150 mg (as palmitate)/5 mL.
- acute bacterial meningitis
Oral liquid: 250 mg/5 mL (anhydrous) [c].
Powder for injection: 1 g (sodium succinate) in vial.
Solution for IV infusion: 2 mg/ mL (as hyclate) [c].

FIRST CHOICE SECOND CHOICE

Tablet: 250 mg (as hydrochloride).

- acute invasive bacterial diarrhoea / -cholera

ciprofloxacin
dysentery - complicated intraabdominal
infections
- low-risk febrile neutropenia
(mild to moderate)
- pyelonephritis
Solid or prostatitis
oral dosage form: 500(mild
mg. to
moderate)
Powder for oral liquid: 125 mg/5 mL; 250 mg/5 mL

Powder for injection: 500 mg in vial

*erythromycin may be an alternative.

clarithromycin* FIRST CHOICE SECOND CHOICE

†clarithromycin is also listed for use in combination regimens for

-community acquired pneumonia - pharyngitis
eradication of
(severe)
Capsule: 150 mg (as hydrochloride).
H. pylori in adults.

Injection: 150 mg (as phosphate)/ mL.

FIRST CHOICE SECOND CHOICE

clindamycin Oral liquid: 75 mg/5 mL (as palmitate) [c].

- bone and joint infections

Oral liquid: 25 mg/5 mL [c]; 50 mg/5 mL
(anhydrous) [c]. Solid oral dosage form: 50 mg [c];
100 mg (as hyclate). Powder for injection: 100 mg
in vial

a Use in children <8 years only for life-threatening infections when no alternative exists.
 FIRST CHOICE SECOND CHOICE

- Chlamydia trachomatis - cholera [c]

doxycycline a - cholera -community acquired
pneumonia (mild to
moderate)
Injection: 10 mg; 40 mg (as sulfate)/ mL in 2- mL vial.
FIRST CHOICE - exacerbations
SECOND CHOICE of COPD

- community acquired pneumonia - Neisseria gonorrhoeae

gentamicin (severe)
[c]
Injection: 500 mg in 100- mL vial.
- complicated severe acute malnutrition
[c]
Oral liquid:
- sepsis 200 mg
in neonates (aschildren
and benzoate)/5
[c] mL.
metronidazole
Suppository: 500 mg; 1 g.
FIRST CHOICE SECOND CHOICE

Tablet: 200 mg to 500 mg.

- C. difficile infection - complicated intraabdominal
infections
- complicated intraabdominal infections
(mild to moderate)
(mild to moderate)
- complicated intrabdominal infections
Oral liquid: 25 mg/5 mL [c].
(severe)
- Trichomonas vaginalis
Tablet: 100 mg.
FIRST CHOICE SECOND CHOICE
nitrofurantoin

-Powder
lower urinary tract infections
for injection: 2 g (as hydrochloride) in vial.
FIRST CHOICE SECOND CHOICE
spectinomycin

Injection: - Neisseria gonorrhoeae

80 mg + 16 mg/ mL in 5- mL ampoule;
80 mg + 16 mg/ mL in 10- mL ampoule.

Oral liquid: 200 mg + 40 mg/5 mL.

FIRST
Tablet:CHOICE
100 mg + 20 mg; 400 mg + 80 mg;SECOND
800 mg CHOICE
+ 160 mg.
sulfamethoxazole +
trimethoprim* -*single
lower urinary tract infections
agent trimethoprim - acute invasive
may be an alternative diarrhoea
for lower
urinary tract infection. / bacterial dysentery
 Capsule: 125 mg; 250 mg (as hydrochloride).

SECOND CHOICE
vancomycin

- C. difficile infection
Complementary List
Powder for injection: 250 mg (as hydrochloride) in vial.

vancomycin FIRST CHOICE SECOND CHOICE

-high-risk febrile neutropenia

Complementary List – RESERVE GROUP
daptomycin Powder for injection: 350 mg; 500 mg in vial
fosfomycin Powder for injection: 2 g; 4 g (as sodium) in vial
Injection for intravenous administration: 2 mg/ mL in
300 mL bag.
oxazolindinon
es e.g.,
Powder for oral liquid: 100 mg/5 mL.
linezolid
polymyxin Powder for injection: 1 million I.U. (as colistemethate
s e.g., sodium) in vial
Tablet: 400 mg; 600 mg.
colistin
tigecycline Powder for injection: 50 mg in vial
Antifungal medicines
Powder for injection: 50 mg in vial (as sodium
amphotericin B deoxycholate or
Vaginal
liposomalcream: 1%; 10%.
complex).
clotrimazole
Vaginal
Capsule:tablet:
50 mg.100 mg; 500 mg.

fluconazole Injection: 2 mg/ mL in vial.

Capsule: 250 mg.

Oral liquid: 50 mg/5 mL.
flucytosine
Infusion: 2.5 g in 250 mL.
Oral liquid: 125 mg/5 mL [c].
griseofulvin
Solid oral100
Capsule: dosage
mg. form: 125 mg; 250 mg.

Oral liquid: 10 mg/mL.

* For treatment of chronic pulmonary aspergillosis,

itraconazole* histoplasmosis, sporotrichosis, paracoccidiodomycosis,
mycoses caused by T. marneffei and
chromoblastomycosis; and prophylaxis of
histoplasmosis and infections caused by T. marneffei in
AIDS patients.
 Lozenge: 100 000 IU.

Oral liquid: 50 mg/5 mL [c]; 100 000 IU/ mL [c].

nystatin
Pessary: 100 000 IU.
Tablet: 50 mg; 200 mg

Tablet: 100 000 IU; 500 000 IU.

Powder for injection: 200 mg in vial

voriconazole* Powder for oral liquid: 40 mg/mL

Complementary List
*For treatment of chronic pulmonary aspergillosis
potassium iodide Saturated solution.
and acute invasive aspergillosis.
Antiviral medicines
Antiherpes medicines
Oral liquid: 200 mg/5 mL [c].

aciclovir Powder for injection: 250 mg (as sodium salt) in vial.

Antiretrovirals
Tablet: 200 mg.
Tablet: 300 mg (as sulfate).
abacavir (ABC)
Tablet (dispersible, scored): 60 mg (as sulfate) [c].
Oral liquid: 50 mg/5 mL [c].
lamivudine (3TC)
Tablet:
Tablet: 150
300 mg.
mg (tenofovir disoproxil fumarate –
equivalent to
tenofovir disoproxil fumarate† (TDF) 245 mg tenofovir disoproxil).
Capsule: 250 mg.
†also indicated for pre-exposure prophylaxis.
Oral liquid: 50 mg/5 mL.

Solution for IV infusion injection: 10 mg/ mL in

zidovudine (ZDV or AZT)
20- mL vial.

Tablet:
Tablet: 300
200 mg.
mg (scored); 600 mg.
efavirenz (EFV or EFZ) a
Tablet (dispersible,
a >3 years or >10 kg weight.
scored): 60 mg [c].
Oral liquid: 50 mg/5 mL.

nevirapine (NVP) a Tablet: 50 mg (dispersible); 200 mg.

a > 6 weeks
 Solid oral dosage form: 100 mg; 300 mg (as sulfate).
atazanavir a
a >25 kg. (heat stable): 300 mg (as sulfate) + 100 mg.
Tablet
atazanavir + ritonavir

Tablet: 75 mg; 400 mg; 600 mg; 800 mg

darunavir a
a >3 years
Oral liquid: 400 mg + 100 mg/5 mL.

lopinavir + ritonavir (LPV/r) Tablet (heat stable): 100 mg + 25 mg; 200 mg + 50 mg.

Oral liquid: 400 mg/5 mL.

Capsule containing oral pellets: 40 mg + 10 mg [c].
ritonavir

dolutegravir Tablet
Tablet:(heat
50 mgstable): 25 mg; 100 mg.
Tablet (chewable): 25 mg; 100 mg.

Tablet: 400 mg
raltegravir*

FIXED-DOSE COMBINATIONS *for use in pregnant women and in second-line

regimens in accordance with WHO treatemnt
Tablet (dispersible, scored): 60 mg (as sulfate) + 30
guidelines.
abacavir + lamivudine mg; 120 mg
(as sulfate)
Tablet: 600+mg
60 +mg.
200 mg + 300 mg (disoproxil fumarate
equivalent to 245 mg tenofovir disoproxil).

efavirenz + emtricitabine* + tenofovir *Emtricitabine (FTC) is an acceptable alternative to

3TC, based on knowledge of the pharmacology, the
Tablet: 400
resistance mg + 300
patterns andmg + 300trials
clinical mg (disoproxil
of
efavirenz + lamivudine + tenofovir fumarate equivalent
antiretrovirals. to 245 mg tenofovir
disoproxil)
Tablet: 200 mg + 300 mg (disoproxil fumarate
equivalent to
245 mg tenofovir disoproxil).

emtricitabine* + tenofovir† *Emtricitabine (FTC) is an acceptable alternative to

3TC, based on knowledge of the pharmacology, the
lamivudine + nevirapine + zidovudine resistance
Tablet: 30patterns
mg + 50 and
mg +clinical
60 mg trials of mg + 200 mg +
[c]; 150
antiretrovirals.
300 mg.

lamivudine + zidovudine Tablet: 30 mg + 60 mg [c]; 150 mg + 300 mg.

† combination also indicated for pre-exposure
prophylaxisinfections
Medicines for prevention of HIV-related opportunistic
isoniazid + pyridoxine + sulfamethoxazole +
Tablet (scored): 300 mg + 25 mg + 800 mg + 160 mg
trimethoprim
Other antivirals
 Injection for intravenous administration: 800 mg
and 1 g in 10- mL phosphate buffer solution.

ribavirin* Solid oral dosage form: 200 mg; 400 mg; 600 mg.

Tablet: 450 mg.

* For the treatment of viral haemorrhagic fevers
valganciclovir*
*For the treatment of cytomegalovirus retinitis (CMVr).
Complementary list
Capsule: 30 mg; 45 mg; 75 mg (as phosphate).

Oral powder: 12 mg/ mL.

oseltamivir*

Antihepatitis medicines * severe illness due to confirmed or suspected influenza

virus infection in critically ill hospitalized patients
Oral liquid: 0.05 mg/ mL

entecavir Tablet: 0.5 mg; 1 mg

Tablet: 300 mg (tenofovir disoproxil fumarate –
tenofovir disoproxil fumarate (TDF) equivalent to
Medicines for hepatitis C 245 mg tenofovir disoproxil).
sofosbuvir Tablet: 400 mg
simeprevir Capsule 150 mg
daclatasvir Tablet: 30 mg; 60 mg (as hydrochloride)
dasabuvir Tablet: 250 mg

Other antivirals
Injection for intravenous administration: 800 mg and
1 g in 10-
mL phosphate buffer solution.

ribavirin*
Solid oral dosage form: 200 mg; 400 mg; 600 mg.
Complementary List
* Foror
Vial the treatment
prefilled of hepatitis C, in
syringe:
combination with peginterferon and/or direct
acting anti-viral medicines
180 micrograms (peginterferon alfa-2a),
pegylated interferon alfa (2a or 2b) *
80 microgram, 100 microgram (peginterferon alfa-2b).
FIXED-DOSE COMBINATIONS

* To be used in combination with ribavirin.

Alternative+combinations
ledipasvir sofosbuvir of DAAs from different pharmacological
Tablet: classes
90 mg + 400 mg. are possible.
ombitasvir + paritaprevir + ritonavir Tablet: 12.5 mg + 75 mg + 50 mg
sofosbovir + velpatasvir Tablet: 400 mg + 100 mg

Antiprotozoal medicines
 Tablet: 500 mg (furoate).
diloxanide a
a >25 kg.
Injection: 500 mg in 100- mL vial.

metronidazole Oral liquid: 200 mg (as benzoate)/5 mL.

Powder for injection: 50 mg in vial (as sodium

amphotericin B Tablet: 200 mg
deoxycholate orto 500 mg.
miltefosine liposomal
Solid oralcomplex).
dosage form: 10 mg; 50 mg.

paromomycin Solution for intramuscular injection: 750 mg of

paromomycin base (as the sulfate).
sodium stibogluconate or Injection: 100 mg/ mL, 1 vial = 30 mL or 30%,
meglumine antimoniate equivalent to approximately 8.1% antimony
(pentavalent) in 5- mL ampoule.
Antimalarial medicines
Tablet: 153 mg or 200 mg (as hydrochloride).
amodiaquine*
*Oily
To be used in combination
injection: 80 mg/ mL inwith artesunate
1- mL ampoule.50 mg.
artemether*
*Tablet:
For use20
inmg
the+management
120 mg. of severe malaria.

Tablet (dispersible): 20 mg + 120 mg [c].

artemether + lumefantrine*
*Injection:
Not recommended
ampoules,incontaining
the first trimester of
60 mg anhydrous
pregnancy or
artesunic acid in children below 5 kg.

with a separate ampoule of 5% sodium bicarbonate

solution. For use in the management of severe
malaria.

Rectal dosage form: 50 mg [c]; 100 mg [c]; 200 mg

capsules (for pre-referral treatment of severe
artesunate* malaria only; patients should be taken to an
appropriate health facility for follow-up care) [c].
Tablet: 25 mg + 67.5 mg; 50 mg + 135 mg; 100 mg + 270
mg.
Tablet: 50 mg.

artesunate + amodiaquine*
* Other combinations
To be used that deliver
in combination the target doses
with either
artesunate + mefloquine Tablet: 25 mgmefloquine
amodiaquine,
required such + 55
as mg;
153 mg100 mg
or200
or +mg
220
(asmg.
sulfadoxine +
hydrochloride)
pyrimethamine.
with 50 mg artesunate can be alternatives.
Tablet: 60 mg + 180 mg

artesunate + pyronaridine tetraphosphate a Granules: 20 mg + 60 mg [c].

a > 5 kg
 Oral liquid: 50 mg (as phosphate or sulfate)/5 mL.

chloroquine* Tablet: 100 mg; 150 mg (as phosphate or sulfate).

dihydroartemisinin + piperaquine Tablet: 20 mg + 160 mg; 40 mg + 320 mg

* For use only for the treatment of P.vivax infection.
phosphate
a a > 5 kg 100 mg (as hydrochloride or hyclate).
Capsule:

doxycycline* Tablet (dispersible): 100 mg (as monohydrate).

Tablet: 250 mg (as hydrochloride).

* For use only in combination with quinine.
mefloquine*
*Tablet:
To be used in combination
7.5 mg; with artesunate 50 mg.
15 mg (as diphosphate).

primaquine* * Only for use to achieve radical cure of P.vivax and

P.ovale
Injection: 300 mg quinine hydrochloride/ mL in 2- mL
ampoule.
infections, given for 14 days.

quinine* Tablet: 300 mg (quinine sulfate) or 300 mg (quinine

sulfadoxine + pyrimethamine*
For prophylaxis
bisulfate).
Tablet: 500 mg + 25 mg.
* For use only in the management of severe malaria,
*and
Only in combination
should be used in with artesunate
combination with50doxycycline.
mg.
Oral liquid: 50 mg (as phosphate or sulfate)/5 mL.

chloroquine* Tablet: 150 mg (as phosphate or sulfate).

Solid oral dosage form: 100 mg (as hydrochloride or

* For use only in central American regions, for P.vivax
hyclate).
doxycycline a
infections.
Tablet: 250 mg (as hydrochloride).
a >8 years.
mefloquine a
a >5 kg or 100
Tablet: >3 months.
mg (as hydrochloride).
proguanil*

Antipneumocystosis and antitoxoplasmosis*medicines

For use only in combination with chloroquine.

pyrimethamine Tablet: 25 mg.

sulfadiazine Tablet: 500 mg.
Injection:

80 mg + 16 mg/ mL in 5- mL ampoule;
80 mg + 16 mg/ mL in 10- mL ampoule.
sulfamethoxazole + trimethoprim

Oral liquid: 200 mg + 40 mg/5 mL [c].

 Complementary List
pentamidine Tablet: 200 mg; 300 mg (as isethionate).
Antitrypanosomal medicines
African trypanosomiasis
Medicines for the treatment of 1st stage African trypanosomiasis
Powder for injection: 200 mg (as isetionate) in vial.

pentamidine* * To be used for the treatment of Trypanosoma brucei

gambiense
Powder for injection: 1 g in vial.
infection.
suramin sodium* * To be used for the treatment of the initial phase of
Medicines for the treatment of 2 nd stage African trypanosomiasis
Trypanosoma brucei rhodesiense infection.
Injection: 200 mg (hydrochloride)/ mL in 100- mL
bottle.
eflornithine*
Injection: 3.6%
* To be used solution,
for the 5- mLofampoule
treatment (180 mg
Trypanosoma of
brucei
melarsoprol active
gambiense
Tablet: 120 mg.
compound).
infection.

nifurtimox* * Only to be used in combination with

Complementary List [c] eflornithine, for the treatment of Trypanosoma
brucei gambiense infection.
melarsoprol Injection: 3.6% solution in 5- mL ampoule (180
mg of active compound).
American trypanosomiasis
Tablet: 12.5 mg [c];100 mg.
benznidazole
Tablet (scored): 50 mg.
nifurtimox Tablet: 30 mg; 120 mg; 250 mg.
ANTIMIGRAINE MEDICINES
For treatment of acute attack
acetylsalicylic acid Tablet: 300 mg to 500 mg.

ibuprofen [c] Tablet: 200 mg; 400 mg.

Oral liquid: 120 mg/5 mL [c]; 125 mg/5 mL [c].
paracetamol

For prophylaxis Tablet: 300 mg to 500 mg.

propranolol Tablet: 20 mg; 40 mg (hydrochloride).

ANTINEOPLASTICS AND IMMUNOSUPPRESSIVES

Immunosuppressive
Medicines listed belowmedicines
should be used according to protocols for treatment of the diseases.
Complementary List
 Powder for injection: 100 mg (as sodium salt) in vial.
azathioprine
Tablet (scored):
Capsule: 25 mg. 50 mg.

ciclosporin Concentrate for injection: 50 mg/ mL in 1- mL

ampoule for organ transplantation.
Cytotoxic and adjuvant medicines
Complementary List
Capsule: 10 mg.
all-trans retinoid acid (ATRA)

allopurinol [c] Acute

Tablet: 100 promyelocytic
mg; 300 mg. leukaemia.
Powder for injection: 10 000
asparaginase IU in vial.

Injection: 45 mg/0.5 mL; 180

Acute lymphoblastic
mg/2 mL.
leukaemia.
bendamustine
Chronic
Powder lymphocytic
for injection: leukaemia
15 mg (as sulfate) in vial.
Follicular lymphoma
Hodgkin lymphoma
bleomycin Kaposi sarcoma
Ovarian
Injection: germ
3 mg/ mLcell tumour
in 10- mL ampoule.
Testicular germ cell tumour
Tablet: 15 mg.

calcium folinate Early stage colon cancer

Early stage rectal cancer

Gestational trophoblastic neoplasia
Tablet: 150 mg; 500 mg.
Metastatic colorectal cancer
Osteosarcoma
Early stage colon cancer
capecitabine Burkitt lymphoma
Early stage rectal cancer
Metastatic
Injection: breast
50 mg/5 mL;cancer
150 mg/15 mL; 450 mg/45
mL; 600 mg/60 mL.
Metastatic colorectal cancer

Early stage breast cancer

carboplatin Epithelial ovarian cancer
Nasopharyngeal cancer
Non-small cell lung cancer
Tablet: 2 mg.
chlorambucil Osteosarcoma
Retinoblastoma
Chronic lymphocytic leukaemia.
 Injection: 50 mg/50 mL; 100 mg/100 mL.

Cervical cancer (as a radio-sensitizer)

Head and neck cancer (as a radio-sensitizer)

Nasopharyngeal cancer (as a radio-sensitizer)

cisplatin Non-small cell lung cancer

Osteosarcoma
Powder for injection: 500 mg in vial.
Ovarian germ cell tumour
Testicular germ cell tumour
Tablet: 25 mg.

Chronic lymphocytic leukaemia

Diffuse large B-cell lymphoma
Early stage breast cancer
Gestational trophoblastic neoplasia
cyclophosphamide Hodgkin lymphoma
Follicular lymphoma
Powder for injection: 100
Rhabdomyosarcoma
mg in vial.
Ewing sarcoma
Acute myelogenous
Acute lymphoblasticleukaemia
leukaemia
cytarabine
Burkittlymphoblastic
Acute lymphoma leukaemia
Powder for injection: 100 mg in vial.
Metastatic
Acute breast cancer.
promyelocytic leukaemia
dacarbazine
Burkitt lymphoma.
Hodgkinforlymphoma
Powder injection: 500
micrograms in vial.
dactinomycin

Gestational trophoblastic neoplasia

Tablet: 20 mg; 50 mg; 70 mg; 80 mg; 100
Rhabdomyosarcoma
dasatinib mg; 140 mg.
Wilms tumour
Powder for injection: 50 mg (hydrochloride) in vial.
Imatinib-resistant chronic
myeloid leukaemia
Acute lymphoblastic leukaemia
daunorubicin Acute myelogenous leukaemia
Acute
Injection: 20promyelocytic
mg/ mL; 40 leukaemia
mg/ mL.

docetaxel
Early stage
breast cancer
Metastatic
breast cancer
 Powder for injection: 10 mg; 50 mg (hydrochloride) in
vial.

Diffuse large B-cell lymphoma

Early stage breast cancer
Hodgkin lymphoma
Kaposi sarcoma

doxorubicin Follicular lymphoma

Metastatic breast cancer
Capsule: 100 mg.
Osteosarcoma
Ewing sarcoma
Injection: 20 mg/ mL in 5- mL
Acute lymphoblastic leukaemia
ampoule.
Wilms tumour
Testicular germ cell tumour
Burkitt lymphoma
Gestational trophoblastic neoplasia
etoposide Hodgkin lymphoma
Non-small cell lung cancer
Injection: 120germ
Ovarian micrograms/0.2
cell tumour mL; 300
micrograms/0.5 mL; 480 micrograms/0.8 mL in pre-
Retinoblastoma
filled syringe 300 micrograms/mL in 1- mL vial, 480
mg/1.6Ewing
mL insarcoma
1.6- mL vial.

Acute lymphoblastic leukaemia

Primary prophylaxis in patients at high risk for
Burkitt lymphoma
developing febrile neutropenia associated with
filgrastim myelotoxic chemotherapy.
Secondary prophylaxis for patients who
Powder forexperienced
have injection: 50 mg (phosphate)
neutropenia in vial.
following
prior myelotoxic chemotherapy
fludarabine To10
Tablet: facilitate
mg administration of dose dense
chemotherapy regimens
Injection: 50 mg/ mL in 5- mL
Chronic lymphocytic leukaemia.
ampoule.

Early stage breast cancer

fluorouracil Early stage colon cancer
Early
Powder for stage rectal200
injection: cancer
mg in vial, 1 g in vial.
Metastatic colorectal cancer
gemcitabine Epithelial ovariancancer.
cancer
Nasopharyngeal
Solid oral dosage
Non-small form:
cell lung200 mg; 250 mg; 300 mg; 400
cancer
mg; 500 mg;
hydroxycarbamide 1 g.
 Powder for injection: 500 mg vial; 1-g vial; 2-g vial.

Testicular germ cell tumour

Ovarian germ cell tumour
ifosfamide
Osteosarcoma
Tablet: 100 mg; 400 mg.
Rhabdomyosarcoma
Ewing sarcoma
imatinib Chronic myeloid leukaemia
Injection: 40 mg/2 mLstromal
Gastrointestinal in 2- mL vial; 100 mg/5 mL in 5-
tumour
mL vial; 500 mg/25 mL in 25- mL vial.
irinotecan
Metastatic
Tablet: 50 mg. colorectal cancer.

mercaptopurine Acute lymphoblastic leukaemia

Injection:
Acute100 mg/ mL in 4-leukaemia.
promyelocytic mL and 10- mL ampoules.

Tablet: 400 mg;

600 mg.

mesna Testicular germ cell tumour

Ovarian germ cell tumour
Powder for injection: 50 mg (as sodium salt) in vial.
Osteosarcoma
Rhabdomyosarcoma
Tablet: 2.5 mg (as sodium salt).
Ewing sarcoma.
Early stage breast cancer
methotrexate
Gestational trophoblastic neoplasia
Capsule: 150 mg; 200 mg.
Osteosarcoma
nilotinib Acute lymphoblastic leukaemia
Imatinib-resistant
Injection: chronic
50promyelocytic
mg/10 mL in 10- mLmyeloid leukaemia
vial; 100 mg/20 mL in
Acute leukaemia
20- mL vial;
200 mg/40 mL in 40- mL vial.

oxaliplatin
Powder for injection: 50 mg, 100 mg in vial.
Powder for injection: 6
mg/stage
Early mL. colon cancer

Metastatic colorectal cancer

Epithelial ovarian cancer
Early stage breast cancer
paclitaxel Metastatic breast cancer
Kaposi sarcoma
 procarbazine Capsule: 50 mg (as hydrochloride).
Injection: 100 mg/10 mL in 10- mL vial; 500 mg/50 mL
in 50- mL
vial.
rituximab
Diffuse large B-cell lymphoma
Solid oral dosage form: 40 mg.
Chronic lymphocytic leukaemia
tioguanine [c]
Follicular
Acute lymphoma.leukaemia.
lymphoblastic
Powder for injection: 60 mg; 150 mg; 440 mg in vial

trastuzumab Early stage HER2 positive breast cancer

Powder for injection:
Metastatic HER210 mg (sulfate)
positive in vial.
breast cancer.

Hodgkin lymphoma
vinblastine Kaposi sarcoma.
Testicular
Powder germ cell
for injection: tumour
1 mg; 5 mg (sulfate) in vial.
Ovarian germ cell tumour
Diffuse large B-cell lymphoma
Gestational trophoblastic neoplasia
Hodgkin lymphoma
Kaposi sarcoma
Follicular lymphoma
vincristine Retinoblastoma
Rhabdomyosarcoma
Injection: 10 mg/mL in 1- mL vial; 50 mg/5 mL in 5- mL
vial. Ewing sarcoma
vinorelbine Acute lymphoblastic leukaemia
Non-small cell lung
Wilms tumour
Concentrate solution forcancer
infusion: 4 mg/5 mL in 5- mL
vial. Metastatic breast cancer
Burkitt lymphoma.
zoledronic acid
Solution for infusion: 4 mg/100 mL in 100- mL bottle.
Hormones and antihormones
Complementary List Malignancy-related bone disease
Tablet: 1 mg.

anastrozole Early stage breast cancer

Tablet: 50 mg. breast cancer.
Metastatic
bicalutamide
Metastatic prostate cancer.
 Injection: 4 mg/ mL in 1- mL ampoule (as disodium
phosphate salt).
dexamethasone
Oral liquid: 2 mg/5 mL [c].
Dose form

Acute lymphoblastic leukaemia.

leuprorelin Early stage breast cancer
Powder for injection:
Metastatic 100cancer
prostate mg (as sodium succinate) in
hydrocortisone vial.

Injection: 40 mg/ mL (as sodium succinate) in 1- mL

Acutevial
single-dose lymphoblastic
and leukaemia.

5- mL multi-dose vials; 80 mg/ mL (as sodium succinate)

methylprednisolone [c] in 1- mL
single-dose vial.
prednisolone Oral liquid: 5 mg/
mL [c].
Acute lymphoblastic leukamia.

Tablet: 5 mg; 25 mg.

Chronic lymphocytic leukaemia

Diffuse large B-cell lymphoma
Tablet: 10 mg;lymphoma
Hodgkin 20 mg
(as citrate).
Follicular lymphoma
tamoxifen
Acute lymphoblastic leukaemia
Early stage
ANTIPARKINSONISM MEDICINES
breast
Burkittcancer
lymphoma
Injection: 5 mg (lactate) in 1- mL ampoule.
Metastatic
biperiden
breast cancer
Tablet:
Tablet: 2100
mgmg(hydrochloride).
levodopa + carbidopa + 10 mg; 100 mg + 25 mg; 250 mg + 25
mg
MEDICINES AFFECTING THE BLOOD
Antianaemia medicines
Oral liquid: equivalent to 25 mg iron (as sulfate)/ mL.
ferrous salt
Tablet:
Tablet: equivalent
equivalent to
to 60
60 mg
mg iron.
iron + 400 micrograms folic
ferrous salt + folic acid acid
(nutritional
Tablet: 400 supplement for1use
micrograms*; mg;during
5 mg. pregnancy).

folic acid *periconceptual use for prevention of first occurrence

of neural tube
Injection: 1 mgdefects
(as acetate, as hydrochloride or as
hydroxocobalamin sulfate) in 1-

Complementary List mL ampoule.

 Injection: pre-filled syringe

1000IU/ 0.5 mL; 2000IU/ 0.5 mL; 3000IU/ 0.3 mL;

4000IU/ 0.4 mL;
erythropoiesis-stimulating agents* 5000IU/ 0.5 mL; 6000IU/ 0.6 mL; 8000IU/ 0.8mL; 10
000IU/ 1 mL;
20 000IU/ 0.5 mL; 40 000IU/ 1 mL
Medicines affecting coagulation
Injection: ampoule or pre-filled syringe
* the square box applies to epoetin alfa, beta and theta,
darbepoetin alfa, methoxy polyethylene glycol-epoetin
beta,and
20 mg/0.2their
mL;respective
40 mg/0.4biosimilars.
mL; 60 mg/0.6 mL; 80
enoxaparin* mg/0.8 mL; 100 mg/1 mL; 120 mg/0.8 mL; 150 mg/1
mL
Injection: 1000 IU/ mL; 5000 IU/ mL; 20 000 IU/ mL in
heparin sodium 1- mL
*Alternatives are limited to nadroparin and dalteparin
ampoule. 1 mg/ mL [c]; 10 mg/ mL in 5- mL ampoule.
Injection:
phytomenadione
Tablet: 10 10
Injection: mg.mg/ mL in 5- mL ampoule.
protamine sulfate
tranexamic acid Injection: 100 mg/ mL in 10- mL ampoule.
warfarin Tablet: 1 mg; 2 mg; 5 mg (sodium salt).
Complementary List [c]
Injection: 4 micrograms/ mL (as acetate) in 1- mL
desmopressin ampoule.

heparin sodium Injection: 1000 IU/ mL; 5000 IU/ mL in 1- mL ampoule.

Nasal spray: 10 micrograms (as acetate) per dose
protamine sulfate Injection: 10 mg/ mL in 5- mL ampoule.
warfarin Tablet: 0.5 mg; 1 mg; 2 mg; 5 mg (sodium salt).
Other medicines for haemoglobinopathies
Complementary List
Powder for injection: 500 mg (mesilate) in vial.
deferoxamine* * Deferasirox oral form may be an alternative, depending
on cost and
hydroxycarbamide Solid oral dosage form: 200 mg; 500 mg; 1 g.
availability.
CARDIOVASCULAR MEDICINES

Antianginal medicines
Tablet: 1.25 mg; 5 mg.
bisoprolol*
*Tablet
includes metoprolol
(sublingual): and
500 carvedilol as alternatives.
micrograms.
glyceryl trinitrate
 isosorbide dinitrate Tablet (sublingual): 5 mg.
verapamil Tablet: 40 mg; 80 mg (hydrochloride).

Antiarrhythmic medicines
Tablet: 1.25 mg; 5 mg.
bisoprolol*
*Injection:
includes250
metoprolol and carvedilol
micrograms/ as alternatives.
mL in 2- mL ampoule.

digoxin Oral liquid: 50 micrograms/ mL.

Injection: 100 micrograms/ mL (as acid tartrate or

epinephrine (adrenaline) Tablet: 62.5 micrograms; 250 micrograms.
hydrochloride) in 10- mL ampoule.
lidocaine Injection: 20 mg (hydrochloride)/ mL in 5- mL
ampoule.
Injection: 2.5 mg (hydrochloride)/ mL in 2- mL
ampoule.
verapamil

Complementary List
Tablet: 40 mg; 80 mg (hydrochloride).

20th WHO Model List of Essential Medicines (March 2017) page 34

 Injection: 50 mg/ mL in 3- mL ampoule (hydrochloride).
amiodarone
Tablet: 100 mg; 200 mg; 400 mg (hydrochloride).
Antihypertensive medicines
amlodipine Tablet: 5 mg (as maleate, mesylate or besylate).
Tablet: 1.25 mg; 5 mg.

bisoprolol* * includes atenolol, metoprolol and carvedilol as

alternatives. Atenolol should not be used as a first-line
enalapril agent in 2.5
Tablet: uncomplicated
mg; 5 mg (ashypertension in patients >60 years
hydrogen maleate).
Powder for injection: 20 mg (hydrochloride) in ampoule.

Tablet: 25 mg; 50 mg (hydrochloride).

hydralazine* * Hydralazine is listed for use only in the acute management

of severe pregnancy-induced hypertension. Its use in the
treatment
Oral of 50
liquid: essential
mg/5 hypertension
mL. is not recommended in
view of the evidence of greater efficacy and safety of other
hydrochlorothiazide
medicines.
Solid oral dosage
Tablet: 250 mg. form: 12.5 mg; 25 mg.

* Methyldopa is listed for use only in the management of

methyldopa* pregnancy-induced hypertension. Its use in the
treatment of essential hypertension is not recommended
losartan in view of25the
Tablet: evidence
mg; 50 mg; of
100greater
mg. efficacy and safety of
other medicines.
Complementary List
sodium nitroprusside Powder for infusion: 50 mg in ampoule.
Medicines used in heart failure
Tablet: 1.25 mg; 5 mg.
bisoprolol*
*Injection:
includes250
metoprolol and carvedilol as alternatives.
micrograms/ mL in 2- mL ampoule.

digoxin Oral liquid: 50 micrograms/ mL.

enalapril Tablet: 2.5 mg; 5 mg (as hydrogen maleate).

Tablet: 62.5 micrograms; 250 micrograms.
 Injection: 10 mg/ mL in 2- mL ampoule.

furosemide Oral liquid: 20 mg/5 mL [c].

Oral liquid: 50 mg/5 mL.

Tablet: 40 mg.
hydrochlorothiazide
Solid oral dosage form: 25 mg.
losartan Tablet: 25 mg; 50 mg; 100 mg
spironolactone Tablet: 25 mg.
Complementary List
dopamine Injection: 40 mg/ mL (hydrochloride) in 5- mL vial.
Antithrombotic medicines

Anti-platelet medicines
acetylsalicylic acid Tablet: 100 mg.
clopidogrel Tablet: 75 mg; 300 mg
Thrombolytic medicines
Complementary List
streptokinase Powder for injection: 1.5 million IU in vial.
Lipid-lowering agents
Tablet: 5 mg; 10 mg; 20 mg; 40 mg.
simvastatin*
* For use in high-risk patients.
DERMATOLOGICAL MEDICINES (topical)
Antifungal medicines
miconazole Cream or ointment: 2% (nitrate).
selenium sulfide Detergent-based suspension: 2%.
sodium thiosulfate Solution: 15%.
terbinafine Cream: 1% or Ointment: 1% terbinafine hydrochloride.
Anti-infective medicines
Cream (as mupirocin calcium): 2%.
mupirocin
Ointment: 2%.
Aqueous solution: 1:10 000.
potassium permanganate
Cream: 1%.
silver sulfadiazine a
a >2 months.
Anti-inflammatory and antipruritic medicines
Cream or ointment: 0.1% (as valerate).
betamethasone a
a Hydrocortisone preferred in neonates.
Lotion.
calamine
hydrocortisone Cream or ointment: 1% (acetate).

Medicines affecting skin differentiation and proliferation

benzoyl peroxide Cream or lotion: 5%.
coal tar Solution: 5%.
fluorouracil Ointment: 5%.
podophyllum resin Solution: 10% to 25%.
salicylic acid Solution: 5%.
urea Cream or ointment: 5%; 10%.

Scabicides and pediculicides

Lotion: 25%.
benzyl benzoate a
a >2 years.5%.
Cream:
permethrin
Lotion: 1%.
DIURETICS
amiloride Tablet: 5 mg (hydrochloride).
Injection: 10 mg/ mL in 2- mL ampoule.

furosemide Oral liquid: 20 mg/5 mL [c].

hydrochlorothiazide Solid oral dosage form: 25 mg.

Tablet: 10 mg [c]; 20 mg [c]; 40 mg.
mannitol Injectable solution: 10%; 20%.

spironolactone Tablet: 25 mg.

Complementary List [c]
hydrochlorothiazide Tablet (scored): 25 mg.
mannitol Injectable solution: 10%; 20%.
Oral liquid: 5 mg/5 mL; 10 mg/5 mL; 25 mg/5 mL.
spironolactone

GASTROINTESTINAL MEDICINES Tablet: 25 mg.

Complementary List [c]

 Age-appropriate formulations and doses including lipase,
pancreatic enzymes protease and amylase.
Antiulcer medicines
Powder for injection: 40 mg in vial

Omeprazole Powder for oral liquid: 20 mg; 40 mg sachets.

Injection: 25 mg/ mL (as hydrochloride) in 2- mL ampoule.

Solid oral dosage form: 10 mg; 20 mg; 40 mg.

Ranitidine Oral liquid: 75 mg/5 mL (as hydrochloride).

Antiemetic medicines
Tablet: 150 mg (as hydrochloride).
Injection: 4 mg/ mL in 1- mL ampoule (as disodium
phosphate
salt).
dexamethasone
Oral liquid:
Injection: 0.5 (hydrochloride)/
5 mg mg/5 mL; 2 mg/5mLmL.
in 2- mL ampoule.

Solid oral dosage

Oral liquid: form:
5 mg/5 0.5 mg; 0.75 mg; 1.5 mg; 4 mg.
mL [c].
metoclopramide a Tablet: 10 mg
(hydrochloride). a Not in
Injection: 2 mg base/ mL in 2- mL ampoule (as
hydrochloride).
neonates.

Oral liquid: 4 mg base/5 mL.

ondansetron a
Solid oral dosage form: Eq 4 mg base; Eq 8 mg base; Eq
Anti-inflammatory medicines 24 mg base.
Retention enema.
a >1 month.
sulfasalazine Suppository: 500 mg.

Complementary List
Tablet: 500 mg.
Retention enema.

hydrocortisone Suppository: 25 mg (acetate).

Laxatives (the only applies to hydrocortisone retention enema).
senna Tablet: 7.5 mg (sennosides) (or traditional dosage forms).

Medicines used in diarrhoea

 Solid oral dosage form: 20 mg.

zinc sulfate* * In acute diarrhoea zinc sulfate should be used as an

adjunct to oral rehydration salts.
HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES
Adrenal hormones and synthetic substitutes
fludrocortisone Tablet: 100 micrograms (acetate).
hydrocortisone Tablet: 5 mg; 10 mg; 20 mg.
Androgens
Complementary List
testosterone Injection: 200 mg (enanthate) in 1- mL ampoule.
Contraceptives
Oral hormonal contraceptives
ethinylestradiol + levonorgestrel Tablet: 30 micrograms + 150 micrograms.
ethinylestradiol + norethisterone Tablet: 35 micrograms + 1 mg.
levonorgestrel Tablet: 30 micrograms; 750 micrograms (pack of two); 1.5
mg.
ulipristal Tablet: 30 mg (as acetate)

Injectable hormonal contraceptives

estradiol cypionate +
medroxyprogesterone acetate Injection: 5 mg + 25 mg.
Injection (intramuscular): 150 mg/ mL in 1- mL vial.

medroxyprogesterone acetate Injection (subcutaneous): 104 mg/0.65 mL in pre-filled

syringe or single-dose injection delivery system.
norethisterone enantate Oily solution: 200 mg/ mL in 1- mL ampoule.

Insulins and other medicines used for diabetes

Solid oral dosage form: (controlled-release tablets) 30
mg; 60 mg;

gliclazide* 80 mg.

glucagon Injection: 1 mg/ mL.

insulin injection (soluble)
intermediate-acting insulin
* glibenclamide not suitable above 60 years.
Injection: 40 IU/ mL in 10- mL vial; 100 IU/ mL in 10- mL
vial.
Injection: 40 IU/ mL in 10- mL vial; 100 IU/ mL in 10- mL
vial (as compound insulin zinc suspension or isophane
insulin).
metformin Tablet: 500 mg (hydrochloride).
Complementary List [c]
metformin Tablet: 500 mg (hydrochloride).

Ovulation inducers
Complementary List
clomifene Tablet: 50 mg (citrate).
Progestogens
medroxyprogesterone acetate Tablet: 5 mg.

Thyroid hormones and antithyroid medicines

Tablet: 25 micrograms [c]; 50 micrograms; 100 micrograms
levothyroxine
(sodium salt).
potassium iodide Tablet: 60 mg.
propylthiouracil Tablet: 50 mg.

Complementary List [c]

Lugol's solution Oral liquid: about 130 mg total iodine/ mL.
potassium iodide Tablet: 60 mg.
propylthiouracil Tablet: 50 mg.
OPHTHALMOLOGICAL PREPARATIONS
Anti-infective agents
aciclovir Ointment: 3% W/W.
azithromycin Solution (eye drops): 1.5%.
Ointment: 0.5% [c]
erythromycin*
*Infections due to Chlamydia trachomatis or Neisseria
gentamicin Solution (eye drops): 0.3% (sulfate).
gonorrhoea.
natamycin Suspension: (eye drops): 5%
ofloxacin Solution (eye drops): 0.3%.
tetracycline Eye ointment: 1% (hydrochloride).

Anti-inflammatory agents
prednisolone Solution (eye drops): 0.5% (sodium phosphate).
Local anaesthetics
 Solution (eye drops): 0.5% (hydrochloride).
tetracaine a
a Not in preterm neonates.
Miotics and antiglaucoma medicines
acetazolamide Tablet: 250 mg.
latanoprost Solution (eye drops): latanoprost 50 micrograms/mL
pilocarpine Solution (eye drops): 2%; 4% (hydrochloride or nitrate).
timolol Solution (eye drops): 0.25%; 0.5% (as hydrogen maleate).

Mydriatics
Solution (eye drops): 0.1%; 0.5%; 1% (sulfate).

* [c] Or homatropine (hydrobromide) or cyclopentolate

atropine* a
(hydrochloride).
Complementary List
epinephrine (adrenaline) a >3 months.(eye drops): 2% (as hydrochloride).
Solution
MEDICINES FOR MENTAL AND BEHAVIOURAL DISORDERS
Medicines used in psychotic disorders
Injection: 25 mg (hydrochloride)/ mL in 2- mL ampoule.

chlorpromazine Oral liquid: 25 mg (hydrochloride)/5 mL.

fluphenazine Injection: 25 mg (decanoate or enantate) in 1- mL ampoule.

Tablet: 100 mg (hydrochloride).
Injection: 5 mg in 1- mL ampoule.
haloperidol
Tablet: 2 mg; 5 mg.form: 0.25 mg to 6.0 mg.
risperidone Solid oral dosage

Complementary List
Injection: 25 mg (hydrochloride)/ mL in 2- mL ampoule.

chlorpromazine [c] Oral liquid: 25 mg (hydrochloride)/5 mL.

clozapine Solid oral dosage form: 25 to 200 mg.

Tablet: 10 mg; 25 mg; 50 mg; 100 mg (hydrochloride).
Injection: 5 mg in 1- mL ampoule.

haloperidol [c] Oral liquid: 2 mg/ mL.

Medicines used in mood disorders

Solid oral dosage form: 0.5 mg; 2 mg; 5 mg.
Medicines used in depressive disorders
amitriptyline Tablet: 25 mg; 75mg. (hydrochloride).
fluoxetine Solid oral dosage form: 20 mg (as hydrochloride).
Complementary List [c]
Solid oral dosage form: 20 mg (as hydrochloride).
fluoxetine a

Medicines used in bipolar disorders a >8 years.

carbamazepine Tablet (scored): 100 mg; 200 mg.

lithium carbonate
valproic acid (sodium valproate)
Medicines for anxiety disorders
diazepam
Solid oral dosage form: 300 mg.
Tablet (enteric-coated): 200 mg; 500 mg (sodium
valproate).
Tablet (scored): 2 mg; 5 mg.

Medicines used for obsessive compulsive disorders

clomipramine Capsule: 10 mg; 25 mg (hydrochloride).

Medicines for disorders due to psychoactive substance use

Chewing gum: 2 mg; 4 mg (as polacrilex).
nicotine replacement therapy (NRT)

Complementary List Transdermal patch: 5 mg to 30 mg/16 hrs; 7 mg to 21

mg/24 hrs.
Concentrate for oral liquid: 5 mg/ mL; 10 mg/ mL
(hydrochloride).

methadone* Oral liquid: 5 mg/5 mL; 10 mg/5 mL (hydrochloride).

MEDICINES ACTING ON THE RESPIRATORY TRACT

* The square box is added to include buprenorphine. The
Antiasthmatic and medicines for chronic obstructive pulmonary
medicines should only bedisease
used within an established
support programme.
Inhalation (aerosol): 50 micrograms (dipropionate) per
beclometasone dose;
Inhalation (aerosol):
100 micrograms 100 micrograms
(dipropionate) per doseper
(asdose; 200 forms).
CFC free
budesonide [c] micrograms
Dry powder inhaler: 100 micrograms + 6 micrograms per
per dose.
budesonide + formoterol dose;
Injection: 1 mg (as
200 micrograms + 6hydrochloride ordose
micrograms per hydrogen tartrate) in
epinephrine (adrenaline)
1- mL ampoule.
ipratropium bromide Inhalation (aerosol): 20 micrograms/metered dose.
 Inhalation (aerosol): 100 micrograms (as sulfate) per dose.

Injection: 50 micrograms (as sulfate)/ mL in 5- mL ampoule.

salbutamol Metered dose inhaler (aerosol): 100 micrograms (as

sulfate) per dose.
VITAMINS AND MINERALS
ascorbic acid Tablet: 50 mg.
Respirator solution for use in nebulizers: 5 mg (as
calcium sulfate)/ mL.
Tablet: 500 mg (elemental).
Oral liquid: 400 IU/ mL.

colecalciferol [c] Solid oral dosage form: 400 IU; 1000 IU.

ergocalciferol * Ergocalciferol
Oral liquid: 250can be used as an
micrograms/ mLalternative.
(10 000 IU/ mL).

Solid oral200
Capsule: dosage
mg. form: 1.25 mg (50 000 IU).
Iodized oil: 1 mL (480 mg iodine); 0.5 mL (240 mg
iodine iodine) in ampoule (oral or injectable); 0.57 mL (308 mg
iodine) in dispenser bottle.
nicotinamide Tablet: 50 mg.
pyridoxine Tablet: 25 mg (hydrochloride).
Capsule: 50 000 IU; 100 000 IU; 200 000 IU (as palmitate).
Oral oily solution: 100 000 IU (as palmitate)/ mL in
multidose dispenser.

Tablet (sugar-coated): 10 000 IU (as palmitate).

retinol
Water-miscible injection: 100 000 IU (as palmitate) in

riboflavin 2- mL ampoule.
Tablet: 5 mg.
sodium fluoride In any appropriate topical formulation.
thiamine Tablet: 50 mg (hydrochloride).

Complementary List
calcium gluconate Injection: 100 mg/ mL in 10- mL ampoule.
EAR, NOSE AND THROAT MEDICINES [c]
acetic acid Topical: 2%, in alcohol.

budesonide Nasal spray: 100 micrograms per dose.

ciprofloxacin Topical: 0.3% drops (as hydrochloride).
 Nasal spray: 0.05%.
xylometazoline a
MEDICINES FOR DISEASES OF JOINTS a Not in children less than 3 months.

Medicines used to treat gout

allopurinol Tablet: 100 mg.

Disease-modifying agents used in rheumatoid disorders (DMARDs)

chloroquine Tablet: 100 mg; 150 mg (as phosphate or sulfate).

Complementary List
azathioprine Tablet: 50 mg.
hydroxychloroquine [c] Solid oral dosage form: 200 mg (as sulfate).
methotrexate Tablet: 2.5 mg (as sodium salt).
penicillamine Solid oral dosage form: 250 mg.
sulfasalazine Tablet: 500 mg.

Juvenile joint diseases

acetylsalicylic acid* (acute or chronic
use)
Suppository: 50 mg to 150
mg. Tablet: 100 mg to 500
mg.
* For use for rheumatic fever, juvenile arthritis, Kawasaki
disease.