Drug Study

Generic / Classification Mechanism of Indication Contraindication Adverse reaction Nursing

Brand Name action Resposibility

Allopurinol Analgesics and Inhibits xanthine Treatment of gout Severe renal Drowsiness,  Assess patient’s
Uricosurics oxidase, an enzyme impairment, and seizures, headache, history of gout.
BN: Allomaron, involved in the children except alopecia,  Assess for pain
Allurase, Elavil, synthesis of uric acid those with ecchymosis, skin  Monitor uric
Llanol, Lopric, without distrupting hyperuricemia rash, epistaxis, levels
Loricid, Purinase, the biosynthesis of secondary to nausea and  Monitor renal
Puristen, Synol, essential purine. malignancy, vomiting, uremia, function
Zulcon, Zyloprim Results in decrease idiopathic acute gouty attack  Monitor
uric acid level hemochromatosis, nutritional status
Dosage: acute gouty attack,  Encourage
30 mg ½ tab hypersensitivity. patient to
Lactation. increase fluid
intake
 Report any
adverse
reactions
 Generic / Classification Mechanism of Indication Contraindication Adverse reaction Nursing
Brand Name action Resposibility

Aspirin Analgesic Relieves pain and Treatment of mild – Hypersensitivity to dizziness, tinnitus,  Assess for pain
reduces moderate pain. salicylates or nausea, dyspepsia,  Assess allergic
BN: aspilet, anadol, inflammation by NSAIDs; bleeding, anemia, reaction
astrix, bayer aspirin, inhibition of haemophilia, increase bleeding  Asses ototoxicity
cortal peripheral bleeding ulcers or times, anaphylactic  Monitor
prostaglandin hemorrhagic states. shock hepatoxicity
Dosage: synthesis. It also Pregnancy (third  Monitor renal
80mg inhibits the synthesis semester) function
or action of other  Encourage
mediators of patient to
inflammation. It acts increase fluid
on the hypothalamic intake
heat regulating  Report any
center to relieve adverse
fever by promoting reactions
sweating and
vasodilation, leading
to heat loss and
cooling by
evaporation. Also
decreases platelet
aggregation by
preventing formation
of thromboxane A, a
platelet aggregating
substance.
 Generic / Classification Mechanism of Indication Contraindication Adverse reaction Nursing
Brand Name action Resposibility

Chlorpromazine Typical Antipsychotic Blocks postsynaptic Management of Comatose states, Drowsiness,  Assess for
dopamine receptors psychotic disorders presence of large jaundice, postural mental status
BN: Laractl, Psynor, in the brain amounts of CNS hypotension, EPS  Monitor CBC,
Thorazine depressants, liver function
presence of bone  Monitor renal
Dosage: marrow depression. function
200mg 1 tab HS hypersensitivity  Assess affect,
coordination,
LOC
 Encourage
patient to
increase fluid
intake
 Teach patient to
use good oral
hygiene
 Inform client that
urine may turn
pink or red
 Report any
adverse
reactions
 Generic / Classification Mechanism of Indication Contraindication Adverse reaction Nursing
Brand Name action Resposibility

Isosorbide dinitrate/ Cardiovascular drug/ Increases blood Preventive and long Acute MI, very low Headache,  Assess for pain
mononitrate Anti-anginal drug supply of oxygen to term treatment of blood pressure, hypotension w/  Monitor BP and
the heart by dilating angina pectoris/ post circulatory collapse, dizziness & nausea. pulse
BN: Angistad, both the arteries and myocardial infarction cerebral Tachycardia.  Monitor renal
Elantan, Imdur veins which supply angina. hemorhhage, function
durules, Isomonit the heart itself hyperthyroidism,  Report any
hypersensitivity adverse
Dosage: reactions
30mg 1tab HS
 Generic / Classification Mechanism of Indication Contraindication Adverse reaction Nursing
Brand Name action Resposibility

Mefenamic Acid Analgesic/ Aspirin like drug that Relief Hypersensitivity. GI & visual  Assess for pain
NSAIDs has analgesic, of pain including Ulceration in the disturbances,  Monitor for
BN: Acidan, Analcid, antipyretic and anti- muscular and upper or lower drowsiness, possible drug
Aprostal, Dolfenal, inflammatory rheumatic intestinal tract. dizziness & induced adverse
Gardan activities. These Pregnancy. nervousness. Skin & reactions
activities appear to other allergic
Dosage: be due to its ability to reaction
50mg inhibit
cyclooxygenase and
also antagonize
certain effects of
prostaglandins.