bacterie factori de patogenitate str antigenica caractere biochimice

pseudomonas 1capula,
2 pili
3 flagel
4 LPZ(endotoxina)
5 enzime -neuramidaza
-proteza
-elastaza
-hemolizina
fosfilipaza
6 toxina
7. biofilm

acinetobacter 1. capsua Cat +

2. fimbrii Ox -
3. LPZ aerobi
4. enzime lipoitice imobili
5. siderofori
6. proteine ale mb ext -> aderenta

vibrio 1.fimbrii -> aderenta 1. antigen fagelar H Cat

2. flagel plar 2.antigen o Ox +
3. LPZ
4.enzim extracel mobili
5. hemolizine glucoza +
6.enterotoxina holerica maltoza +
7. prot ale mb externe nu produce gaz
activit metabolica aupra aa
nitratii -> nitrati

haemophilus 1. capsula(in culturi tinere)

2. igA proteaze
 3. aderenta
4.LPZ
5.comp mb externe

bordetella pili(fimbrii) antigen O - gen imobil

exotoxina-toxina pertusis antigen K -tulpina aerobi
toxina adenilatciclazei indol -
citotoxina traheala H2S -
endotoxina nefermentativ
ureaza +
nitratii -> nitriti
oxideaza aa
Ox +

brucella rezistenta la puterea bactericida a ser imobil

aerob
nu fermenteaza carbohidrati
Cat +
Ox +
nitrati -> nitriti
sensibili la caldura si aciditate

corynebacterium difterie exotoxina difterica facultativ anaerobi

imobili
ureaza -

mycobacterium tuberculosis cord factor tuberculolipide aerobi

multiplicare intracel polizaharide imobili
invazivitatea tuberculoproteine nitrati -> nitriti
supravietuirea in interiorul macrofagelor catalaza
toleranta la NaCl
bacillus anthracis capsula antigen capsular imobili
toxina antigen somatic polizah fermenteaza glucza
produce lecitinaza

Bacilus cereus enterotoxine-termostabila mobil

-termolabila prduce lecitinaza
toxine-necrotica=entero. Termolabila da reactia siragului de perle
-cereolizina hidrolizeaza gelatina
fosfolipaza c

clostridiile gangrenei gazoase toxine - fosfolipaza antigenele toxinei A-E anaerobi

- lecitinaza

clostridium tetani cili peritrichi anaerobi

necapsulati mobili
toxina tetanica - tetanospasmina
-tetanolizina

clostridium botuinum toxina botulinica 8 neurotoxine antigenice anaerobi

-A,B,E -> patogene umane imobili
-C,D ->animale

trepnema pallidum protine ale mb ext ->aderenta haptena lipidica mobile

hialuronidaza antigen proteic de grup aerobi
fibronectina antigen polizaharidic si proteic

leptspira gradul de incovoiere a capetelor ag somaic specific de gen aerobi

factorul de virulenta ag de suprafata pt grup si tip foarte mobile
hemolizina
endotoxina

chalmydia ag specific de gen obigatoriu intracelulari

 ag specific de specie
ag specific de tip

mycoplasma pneumoniae adezina P1 ag proteice (proteina P1) fac anaerob

inhibitor al catalazi ag glicoipidic mobile (prin translatie alunecare
ag comune cu ag tisulare umane

rickettsia capacitatea de inmultire +adapta in tes. ag solubile obligatoriu intracel

deteriorare moderata a cel gazda ag corpusculare
imunitate de premunitie ag lipopolizaharidice

stafilococ exotoxine+anzime proteina a coagulaza +

atasare perete celular cu clamping factor
diseminare
capsula

streptococ piogenes hemolizine - streptolizina A perete cel -> polizaharid C catalaza -

-streptolizina S proteina M -> specifica de tip bacitracina+
fact de diseminare -streptokinaza proteine T,R aslo +
-dezoxiribonc C5a peptidaza -> strept A
- hiauronidaza streptolizina S -> slab antigenica
toxina eritrogena

streptoccosus pneumoniae capsula substanta C specif de spacie

colina (peptidoglic)
pneumolizina
factor de induc a purpurei
neuraminidaza
amidaza