“Pharmacological Assessment of Leaves Extract of Cordia

Obliqua For it’s In Vitro Antioxidant and Antidiabetic Potential”

Saurav Kumar Vishwakarma

2012

D E P A R T M E N T O F P H A R M A C O L O G Y, A I P S - S A G A R ( M . P. )
“PHARMACOLOGICAL ASSESSMENT OF LEAVES EXTRACT OF CORDIA OBLIQUA FOR
ITS IN VITRO ANTIOXIDANT AND ANTIDIABETIC POTENTIAL”

Dissertation submitted to
RAGIV GANDHI PROUDYOGIKI VISWAVIDYALYA BHOPAL

In partial fulfillment for the award of degree

BACHELOR OF PHARMACY

BY
SAURAV K VISHWAKARMA

Under the guidance of

MR. SANTOSH SINGH BHADORIYA

December-2012

DEPARTMENT OF PHARMACOLOGY

ADINA INSTITUTE OF PHARMACEUTICAL SCIENCES

OPPOSITE OF J. L. NEHRU AGRICULTURAL RESEARCH CENTER, BHOPAL ROAD

SAGAR, M.P.
MR. SANTOSH SINGH BHADORIYA DEPARTMENT OF PHARMACOLOGY
Asst. Professor (Pharmacology) Adina Institute of Pharmaceutical
Mail: bhadoriya7@gmail.com Sciences Sagar-470002 (M.P.) INDIA

2012

CERTIFICATE

This is to certify that Saurav Kumar Vishwakarma has

submitted his thesis entitled “Pharmacological assessment of
leaves extract of Cordia Obliqua for its in vitro antioxidant
and anti-diabetic potential” in partial fulfillment of the
requirement for the degree of Master of Pharmacy, with his truly
and honestly observed inferences during his work. He has
completed his project under my supervision. His work is original,
satisfactory and is not submitted anywhere for the award of
degree.

I hereby forward his dissertation for evaluation.

SANTOSH SINGH BHADORIYA

DATE: 27-11-12

PLACE: SAGAR (M.P.)

Name: Saurav K. Vishwakarma Department of pharmacology
Roll no. 0603PY091053 Adina Institute of Pharmaceutical
vishwakarmasaurav@gmail.com Sciences, Sagar-470002 (M.P.)
INDIA

2012

DECLARATION

I hereby declare that the work incorporated in the dissertation

entitled “Pharmacological assessment of leaves extract of
Cordia Obliqua For its In vitro antioxidant and anti-diabetic
potential”, embodies my own work except the guidance and
suggestions received from my supervisor Mr. Santosh Singh
Bhadoriya, Adina institute of Pharmaceutical Sciences, Sagar
(M.P.)India.

Saurav K. Vishwakarma

DATE: 27-11-12

PLACE: SAGAR (MP)

 ACKNOWLEDGEMENT
Compilation of research is an arduous task, which involves consistent and dedicated
mind with regards to the strenuous and hard labour put into it. This would only be made
possible with the benediction, presence of mind and grace of Almighty God. Apart from
personal efforts and steadfastness to work, constant inspiration and encouragement
given by a number of individuals served as the driving force that enabled me to submit
this dissertation in the present form. Inspiration, guidance, direction, co-operation, all
came in abundance and it seems almost an impossible task for me to acknowledge the
same in adequate terms.
It is our privilege pride and honor in expressing my deepest sense of gratitude to
our esteemed inspiring, untiring mentor Mr. Santosh Singh Bhadoriya (Lecturer) of
Department of Pharmacology. No words can express my sincere and deep sense of
reverence for him. I express my profound gratitude to my supervisor for his guidance,
keen interest, constant support and encouragement along with positive criticism
through tenure of this research work.

Words are insufficient to express my gratefulness and indebtedness to Mr. Anuj

Modi (Lecturer-AIPS, Sagar) for their academic help and moral support during my
project work.

I fell complacent to express my gratitude to Prof. Raj Kumar Jain (Principal, AIPS,
Sagar) for helping in building up my concepts and developing the ethics of my
profession and also for his valuable help and providing me the necessary facilities to
carry out this work with great ease and precision.

DATE: 27-11-12
Saurav K Vishwakarma
PLACE: SAGAR B. Pharm (VII SEM)
Roll no. 0603PY091053
 CONTENT LIST

CHAPTER TITLE PAGE NO.

NO.
I INTRODUCTION 1-7
II PLANT PROFILE 8-15
III MATERIAL AND METHODS 16-22
IV EXTRACTION AND PHYTOCHEMICAL SCREENING 23-30
V IN VITRO RESEARCH METHODOLOGY 31-39
VI RESULTS OF PROPOSED STUDY 40-44
VII SUMMARY AND CONCLUSION 45-47
VIII REFERENCES 48-52