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Risk factors for dementia

The Lancet Commission presents a new life-course model showing


potentially modifiable, and non-modifiable, risk factors for dementia.

Bir
th
7% ApoE ε4 allele 5% Percentage reduction
% in new cases of dementia
if this risk is eliminated

Ea
rly li
8%
8% Less education
Less education

fe

M
idl
ife
Hearing lossloss
Hearing
9%
2% Hypertension
Hypertension
Lat 1% Obesity
Obesity

5% Smoking
Smoking
4%
e life

Depression
Depression
3% Physical inactivity
Physical inactivity
2% Social isolation
Low social contact

1% Diabetes
Diabetes

Potentially
Potentially
modifiable
modifiable
35%
35%

Potentially
Potentially
non-modifiable
non-modifiable
65%
65%

The best science for better lives

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