Krish Biotech Partnering Quality Research.. Accreditations : =senasa CIB ERC, ‘4 Krish Biotech Research Private Limited AKrish Biotech Research Pvt. Ltd. (KBRPL) is an independent research based organisation promoted by the Krishi Rasayan Group. The state-of-the-art laboratory of KBRPL is spread over nine thousand square meter of area, established at Kalyani near Kolkata. It is well recognised by National & International regulatory authorities and clients. KBRPL is providing Integrated Discovery, Development and regulatory services, across the Agrochemical, Industrial Chemical, Pharmaceutical and Medical Device Industries, Facility: KBRPLis well equipped to provide Analytical Chemistry, Toxicology and Pharmacology Services. The laboratories of Analytical, Wet and Residue Chemistry, Genetic Toxicology, Eco Toxicology, Inhalation Toxicology, Clinical Chemistry, Histopathology and Pharmacology are adequately spaced and equipped with advanced instruments. There is also a huge Animal Facility with 40 animal experimental room. Cold room facility having two chambers of different temperate ranges is also available to accommodate residue samplesand other temperature sensitive items with adequate separation. Quality & Commitment: KBRPL has been certified for 1SO-17025:2005 by NABL and OECD GLP by National GLP Compliance Monitoring Authority. The Quality Assurance Team is focussed and committed to ensure that highest quality standards are set and maintained. Safety & Security: The Company follows high standard of Safety procedures and provide Safe Working Environment to all its employees and well compliant with National and State regulations. The facility is under CCTV surveillance along with 24X7 security, The access to the Facility is controlled by Access Data Acquisition and Control System. Organisation & Personnel: Testing Facility has well defined Organisational Structure controlled by Test Facility Management. Each function is taken care by Head of the Department / Section. KBRPL is having a pool of well qualified and experienced scientists to carry out the experiments efficiently with precision, Ethics & Animal Welfare : Institutional Animal Ethics Committee (IAEC) ensures benevolent & justified use of animals for Research . The Animal Facility is registered for experimentation and breeding under the CPCSEA, under the Ministry of Environment & Forests, Govt. of Indig Teun ea a cdlytical & Product Chemistry Service: ‘A, Impurity Profiling & Five Batch Analysis © Pre Screening using HPLC-DAD, GC-MS/MS, LC-MS/MS © Method Development & Validation & for Impurity Analysis (SANCO) © Preparation / Procurement of Active as well as Impurity Standards © Analysis of Five different Production Batches for Active & Impurities (>0.06%) © Additional Analysis - Moisture Content, Inorganic Impurities, Acetone Insoluble ete. © Establishment of Mass Blance (98-102%) as per EU/SINDAG/SENASA B. Physical-Chemical Property Testing © For Technical Grade Active ingredient-Physical State, Colour, Odour, Melting Point, Boiling Point, Vapor Pressure, Solubility, Partition co-effcient, Density, Dissociation Constant, Surface Tension, Viscosity, Flash Point/ Flamability, Chemical Composition, Chemical Equivalance, pH ete. © For Formulated Products - Appearance, Bulk Density, Wettability, Suspensibility, Suspension Stability, Emulsion Stability, Wet & Dry Sieve Test, Solution Stability, Surface Tension, Viscosity, Foamability, Dustiness/Fineness, Storage Stability (54° & 0° C), Container Performance Test etc. C. Residue Analysis Persistence & Dissipation in Soil, Plant & Water Harvest Residue Analysis for Active & Significant Degraded Products Method Development & Validation for Residue Analysis Kinetics & Half Life in water (Different pH & Temperature) & Soil (4 Type) in Laboratory coco Major Analytical Equipments © GCwith FID : Varian, Agilent © GC-MS/MS (Ion Trap & TQD) : Varian, Agilent @ HPLC- DAD (3D Analysis & Peak Purity), UV-Vis : Waters,Shimadzu © LC-MS/MS (Triple Quadra pole with Linear lon Trap): ABSciex © viscometer : Brookfield, Density Meter : Anaton Par, Surface Tensiometer : lauda © Melting/Boiling Point Apparatus : Buchii © FtIR & UV-VIS Spectrophotometer : Perkin Elmer etc. Cooera tunes oe ee) ec] eee Reals) Sane