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DRUG STUDY

NAME OF THE MACHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING


DRUG ACTIONS RESPONSIBILITIES

OLANZAPINE
blocks dopamine receptors in Treatment of acute Contraindicated with CNS: Assess for history
Route: the brain, depresses the RAS; mixed or manic episode allergy to olanzapine, Somnolence, dizziness, of allergy too olanzapine.
P.O. blocks serotonin associated with bipolar myeloproliferative nervousness, headache,
receptor sites; anticholinergic, 1disorder and disorder s, severe CNS akathisia, personality Monitor for the many
Frequency: antihistaminic (H1), and alpha- maintenance of bipolar depression, comatose states, disorders, tardive possible drug interactions
BID adrenergic blocking activity 1disorder as lactation. Use cautiously in dyskinesia, before beginning therapy.
may contribute to some of its monotherapy, or elderly or debilitated neuroleptic malignant
Dosage: therapeutic (and adverse) combined with lithium patients, or with CV Syndrome Encourage patient to void
10mg actions; produces or valproate. or cerebrovascular disease, before taking the drug to
fewer extrapyramidal effects dehydration, seizure CV: help decrease anticholinergic
than most antipsychotics. disorders, Alzheimer’s Orthostatic hypotension, effects of urinary retention.
disease, prostate Peripheral edema,
enlargement, narrow-angle tachycardia Take this drug exactly as
glaucoma, prescribed; do not change
history of paralytic ileus GI: dose without consulting your
or breast cancer, pregnancy; Constipation, healthcare provider.
phenylketonuria (if using abdominal pain
orally disintegrating
tablets, contain Respiratory:
phenylalanine). Cough, pharyngitis

Other:
Fever,
Development of diabetes
Mellitus
NAME OF THE MACHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
DRUG ACTIONS RESPONSIBILITIES

DIVALPROEX
Na Increases level Treatment of primary Hepatic dysfunction, The most frequent adverse Assess for Complaints.
of gamma/aminobutyric in generalized seizures, and not urea cycle disorder. effects are GI *Assess for pain.
Route: brain, which decreases ably absence and myoclonic disturbances, particularly
P.O. seizure activity. seizures, and also for in initiation of therapy *Assess for changes in bowel.
partial seizures. Also used
Frequency: to treat acute manic phase of *Assess for EPS.
BID bipolar disorders and for the
prophylaxis of migraine. *Instruct the patient to inform
Dosage:
500mg physician of transient
intestinal cramps, increased
plasma prolactin levels and
EPS occur
NAME OF THE MACHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
DRUG ACTIONS RESPONSIBILITIES

METROPOLOL
Combines reversibly To lower blood pressure Myocardial Infarction in CNS: Nausea Before:
Route: mainly) it% beta- clients) with a HR of 1. Verify doctor’s order
P.O. adrenergic receptors to To decrease intensity of less than 45bpm, in GIT: Diarrhea, vomiting 2. Know the reason for giving
bloc' the response to angina attacks second or third degree drug.
Frequency: sympathetic nerve heart blocks or if SBP is RESP: Shortness of breath, 3. Check for contraindications
BID impulses! Circulating less than 100mmHg bradycardia
4. Verify dosage of drug
catecholamine’s!
Moderate to severe 5. Prepare drug on time
Dosage: noradrenergic drugs HEMATOLOGIC: Bone
cardiac failure
50mg marrow depression, decrease
WBC count, decreased platelet, During:
decrease Hct 1. Verify client’s identity
2. Inform the purpose of the
Hypersensitivity: Rash to fever drug
to anaphylaxis 3. Assess route of
administration
4. Check patient status
5. Administer on time

After:
1. Ensure patient’s safety
2. Monitor accordingly
3. Document all relevant
datas.

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