Beruflich Dokumente
Kultur Dokumente
Dept. of
Department Pharmaceutical Course B.Pharm. Code
Sciences
Pharmaceutical Subject
Subject PHS-54 School EAT 50
Sciences Code
Course
Course Code Course Name L* T* Credits
SNo
01 PHSC 2101 Applied Mathematics and Biostatistics (T) 4 0 4
02 PHSC 2102 Human Anatomy, Physiology and Health Education (T) 4 0 4
03 PHSC 2103 Pharmacognosy and Phytochemistry-I (T) 4 0 4
04 PHSC 2104 Pharmaceutical Chemistry III (Organic Chemistry-II) (T) 3 0 3
05 PHSC 2105 Pharmaceutical Analysis I (T) 4 0 4
06 PHSC 2110 Environmental Studies (T) 3 0 3
Total = 22 0 22
Course
Course Code Course Name P* Credits
SNo
01 PHSC 2106 Human Anatomy, Physiology and Health Education (P) 3 1
02 PHSC 2107 Pharmacognosy and Phytochemistry- I (P) 3 1
03 PHSC 2108 Pharmaceutical Chemistry III (Organic Chemistry-II) (P) 3 1
04 PHSC 2109 Pharmaceutical Analysis I (P) 3 1
Total = 12 04
Course Course
Course Name L* T* Credits
SNo Code
01 PHSC 3101 Physical Pharmaceutics (T) 4 0 4
02 PHSC 3102 Cell and Molecular Biology (T) 2 0 2
Pharmaceutical Chemistry IV
03 PHSC 3103 4 0 4
(Chemistry of Natural Products) (T)
04 PHSC 3104 Pharmaceutical Microbiology (T) 4 0 4
05 PHSC 3105 Pharmaceutical Engineering (T) 4 0 4
Total = 18 0 18
Course Course
Course Name L* T* Credits
S. No. Code
Human Physiology and Pathophysiology of Common
01 PHSC 4101 4 0 4
Diseases (T)
02 PHSC 4102 Dosage Forms Design (T) 4 0 4
03 PHSC 4103 Pharmaceutical Biotechnology (T) 4 0 4
04 PHSC 4104 Pharmacognosy and Phytochemistry- II (T) 4 0 4
Pharmacy Practice (Dispensing and Community
05 PHSC 4105 4 0 4
Pharmacy) (T)
Total = 20 0 20
Course Course
Course Name P* Credits
S. No. Code
Human Physiology and Pathophysiology of Common
01 PHSC 4106 3 1
Diseases (P)
02 PHSC 4107 Dosage Forms Design (P) 3 1
03 PHSC 4108 Pharmaceutical Biotechnology (P) 3 1
04 PHSC 4109 Pharmacognosy and Phytochemistry- II (P) 3 1
Pharmacy Practice (Dispensing and Community
05 PHSC 4110 3 1
Pharmacy) (P)
Total = 15 05
Course Course
Course Name L* T* Credits
S. No. Code
01 PHSC 5101 Cosmetic Technology (T) 4 0 4
02 PHSC 5102 Biochemistry (T) 4 0 4
03 PHSC 5103 Medicinal Chemistry I (T) 3 0 3
04 PHSC 5104 Pharmacology I (T) 3 0 3
05 PHSC 5105 Pharmacognosy and Phytochemistry III (T) 3 0 3
Total = 17 0 17
Course Course
Course Name P* Credits
S. No Code
01 PHSC 5106 Cosmetic Technology (P) 3 1
02 PHSC 5107 Biochemistry (P) 6 2
03 PHSC 5108 Medicinal Chemistry I (P) 3 1
04 PHSC 5109 Pharmacology I (P) 3 1
05 PHSC 5110 Pharmacognosy and Phytochemistry III (P) 3 1
Total = 18 6
Course Course
Course Name L* T* Credits
S. No Code
01 PHSC 6101 Pharmaceutical Industrial Management (T) 3 0 3
02 PHSC 6102 Pharmaceutical Analysis II (T) 4 0 4
03 PHSC 6103 Medicinal Chemistry II (T) 3 0 3
04 PHSC 6104 Pharmacology II (T) 3 0 3
05 PHSC 6105 Pharmaceutical Manufacturing Technology (T) 4 0 4
Total= 17 0 17
Course Course
Course Name P* Credits
S. No Code
01 PHSC 6106 Pharmaceutical Analysis II (P) 6 2
02 PHSC 6107 Medicinal Chemistry II (P) 3 1
03 PHSC 6108 Pharmacology II (P) 3 1
04 PHSC 6109 Pharmaceutical Manufacturing Technology (P) 6 2
05 PHSC 6110 Industrial Tour/Project (P) 0 2
Total= 18 8
Course Course
Course Name L* T* Credits
S. No Code
01 PHSC 7101 Medicinal Chemistry III (T) 3 0 3
02 PHSC 7102 Pharmaceutical Analysis III (T) 4 0 4
03 PHSC 7103 Pharmacology III (T) 3 0 3
04 PHSC 7104 Drug Legislation and Regulatory Affairs (T) 4 0 4
05 PHSC 7105 Clinical & Hospital Pharmacy (T) 4 0 4
Total= 18 0 18
Course Course
Course Name P* Credits
S. No Code
01 PHSC 7106 Medicinal Chemistry III (P) 3 1
02 PHSC 7107 Pharmaceutical Analysis III (P) 3 1
03 PHSC 7108 Pharmacology III (P) 6 2
04 PHSC 7109 Clinical & Hospital Pharmacy (P) 3 1
Total= 15 5
Course Course
Course Name L* T* Credits
S. No Code
01 PHSC 8101 Novel and Controlled Drug Delivery Systems (T) 4 0 4
02 PHSC 8102 Biopharmaceutics & Pharmacokinetics (T) 4 0 4
03 PHSC 8103 Pharmacognosy and Phytochemistry –IV (T) 3 0 3
04 PHSE 8104 Elective (T) 4 0 4
Total = 15 0 15
Course Course
Course Name P* Credits
S. No Code
01 PHSC 8105 Novel and Controlled Drug Delivery Systems (P) 3 1
02 PHSC 8106 Biopharmaceutics & Pharmacokinetics (P) 3 1
03 PHSC 8107 Pharmacognosy and Phytochemistry –IV (P) 3 1
04 PHSC 8108 Project on elective (P) 6 2
Total = 15 05
Theory: 2h/week
Unit – I (09 Hrs.):
English grammar- Parts of speech, articles, preposition, tenses, active and passive speech, direct and
indirect speech.
Presentation techniques- Tips, Dos and don’ts of presentation, notice and placard presentations.
Unit – II (09 Hrs.):
Written skills: Proposal, writing formats, report writing business letters, applications, covering letters,
curriculum vitae designing, summary writing.
Listening- Phonetics and pronunciations (with the help of phonetics dictionary and with tapes from
language laboratory).
Unit – III ( 09 Hrs.):
Etiquettes and grooming.
Group discussion and extempore communication.
Interviews- Tips and model interviews (video shooting and display).
Tutorial: 1h/week
Unit – IV (09 Hrs.):
English grammar- Parts of speech, articles, preposition, tenses, active and passive speech, direct and
indirect speech.
Unit – V (09 Hrs.):
Presentation techniques- Tips, Dos and don’ts of presentation, notice and placard presentations. (3)
Written skills: Proposal, writing formats, report writing business letters, applications, covering letters,
curriculum vitae designing, summary writing.
Books Recommended:
1. Wren and Martin, English Grammar.
2. Tapes from language laboratory, Hyderabad.
10
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 1102 Computer Applications (T) 2 0 2
Hours Per Week
Books Recommended:
1. Block, J.H., Roche, E., Soine, T. and Wilson, C., “Inorganic, Medicinal and Pharmaceutical Chemistry”, Lea and
Febiger.
2. Discher, C.A. et al., Modern inorganic pharmaceutical chemistry, Waveland press.
3. Pharmacopoeia of India, 1996
4. Atherden, L.M., Bentley and Drivers “Text book of Pharmaceutical Chemistry” Oxford University press, London.
12
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Relations of structure with properties like density, melting point, boiling point, solubility, etc.
Books Recommended:
1. Morrison, B.T., and Boyd, R.N., “Organic Chemistry”, Prentics Hall of India Pvt. Ltd., New Delhi.
2. Vogel A.I., “Textbook of Practical Organic chemistry”, ELBS/Longman.
3. Mann, F.G. and Saunders, B.C., “Practical Organic Chemistry”, ELBS/Longman
4. Finar, I.L. Organic Chemistry, Vol.-I and II, ELBS/Longman
5. Hendrikson, Organic Chemistry.
6. S. K. Kashaw and Vikash Mishra Text Book of Organic name reaction, first edition, CBS, New Delhi.
13
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Books Recommended:
1. Ansel: Introduction to Pharmaceutical Dosages Forms
2. Remington's Pharmaceutical Sciences.
3. Indian Pharmacopeia.
4. British Pharmacopeia.
5. Jain & Sharma: The theory and practice of Professional Pharmacy
6. Jain : Pharmaceutical Arithmetic.
7. An introduction to Chemical Engineering - Badger and Banchero.
8. Chemical Engineering - Richardson and Coulson.
9. Introduction to Unit Operation - McCabe and Smith.
10. Theory and Practice of Industrial Pharmacy-R. K. Khar et. al.
11. Bentley's Text Book of Pharmaceutics – S. K. Jain and Vandana Soni
12. M. E. Aulton: Pharmaceutics the science of deosafe form design, Churchill, Living Stone.
13. Shivaranjan V V, Ayurvedic drug and their plant sources, Oxford and IBH publication
14. Mandal P. P. Text book of Homeopathic Pharmacy, new central book agencies.
14
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 1106 Remedial Mathematics (T) 2 2 4
Hours Per Week
Unit- I ( 12 Hrs):
Algebra: Laws of indices, Surds, pure and mixed Surds, Rationalization of surds, Equivalent fraction with a rational
denominator of a surd, Square root, Cube root of surds. Modulus and arguments of a complex number, square root of a
complex number. Solution of quadratic equations, theory of quadratic equations, solution of simultaneous equations and
miscellaneous equations. Logarithms, Properties of logarithms, Arithmetical Geometrical and Hormonical progressions,
permutation and combination.
Unit- II ( 12 Hrs):
Binomial theorem with positive index. Matrices, types of matrices, addition, subtraction, multiplication and transpose of
matrices, adjoint and inverse of a matrix. Application of matrices in solving equations. Determinants and their properties,
applications of determinants in the solution of linear equation.
Unit- III ( 12 Hrs):
Co-ordinate Geometry: Distance formula, area of a triangle and quadrilateral, Equations of a straight line, angle between
straight lines, point o intersection of two straight lines, perpendicular distance of a point from the straight lines, Second
degree equation representing two lines, Equation of circle.
Unit- IV ( 12 Hrs):
Trigonometry: Measurement of angles relation between trigonometric ratio of an angle of a right angle triangle,
complementary and supplementary angle, multiple and submultiple angles, product formulae sum and difference formulae of
trigonometric ratios, identities of trigonometric ratios, relation between sides and angles of any triangle, area of a triangle,
radius of circumscribed, inscribed circles.
Unit- V ( 12 Hrs):
Calculus: Limit of a function, limit at infinity, Differentiation of some function, product rule, quotient rile of differentiation,
differentiation of inverse trigonometric function, implicit function, logarithmic from, parametric form, successive
differentiation, tangent and normal, maxima and minima.
Integration as inverse of differentiation, simple integration formulae, integration by substitution and by parts.
Books Recommended:
1. Algebra by Hall and Knight
2. Coordinate geometry by S. L. Loney.
3. Trigonometry by S. L. Loney.
4. Differential Calculus by Gorakh Prasad.
5. Integral Calculus by Gorakh Prasad.
15
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 1107 Remedial Biology (T) 4 0 4
Hours Per Week
Books Recommended:
1. “Computers Today” by Senders D. H., McGrawHill.
2. “Computer fundamentals” by P. K. Sinha. Third edition, BPB Publication.
3. “Information technology”, Jaiswal, S., Galgotia Pub.
4. Manuals for MS DOS, MS Office, MS Windows, UNIX.
5. “Office 2000/2003 Complete”, BPB Publication.
6. “Internet basic reference A to Z”, by Falk B., BPB, Delhi
7. “Operating Systems” by Stallings,PHI.
8. “Computers in Pharmacy” by Thakur P.S.,Manchanda R.Nand P; Birla Pub.Pvt Ltd.
9. “Programming in ANSI-C by E. Balaguruswamy –Tata Mc. Graw Hill.
10. “Computer Networks” by Tenenbaum A.S., Prentice Hall of India.
11. “Programming with C” by Byron Gottfield.
17
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
Pharmaceutical Chemistry- I
PHSC 1109 3 1
(Inorganic Chemistry) (P)
Hours per week
Limit test of Chloride, Sulphate, Iron, Lead, Arsenic in the given sample.
Books Recommended:
1. Block, J.H., Roche, E., Soine, T. and Wilson, C., “Inorganic, Medicinal and Pharmaceutical Chemistry”, Lea and Febiger.
2. Discher, C.A. et al., Modern inorganic pharmaceutical chemistry, Waveland press.
3. Pharmacopoeia of India, 1996
4. Atherden, L.M., Bentley and Drivers “Text book of Pharmaceutical Chemistry” Oxford University press, London
18
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
Pharmaceutical Chemistry-II
PHSC 1110 3 1
(Organic Chemistry-I) (P)
Hours per week
Synthesis of compounds involving acetylation, benzoylation, bromination, reduction, diazotisation and oxidation.
Books Recommended:
1. Morrison, B.T., and Boyd, R.N., “Organic Chemistry”, Prentics Hall of India Pvt. Ltd., New Delhi.
2. Vogel A.I., “Textbook of Practical Organic chemistry”, ELBS/Longman.
3. Mann, F.G. and Saunders, B.C., “Practical Organic Chemistry”, ELBS/Longman
4. Finar, I.L. Organic Chemistry, Vol.-I and II, ELBS/Longman
5. Hendrikson, Organic Chemistry.
19
B.PHARM. – I SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 1111 Introduction to Pharmaceutics (P) 3 1
Hours per week
Experiments based on theory i.e., Preparation of Waters, Solutions, Syrups, Elixirs, Infusions, Decoctions, Spirits, Jellies,
Mucilages, Lotions, Liniments, Gargles, Enemas, Eye, Ear & Nasal Drops,
Practice in Pharmaceutical Calculations. Experiments based on Size Reduction, Size Separation, Filtration, Extraction.
Books Recommended:
Unit- I ( 12 Hrs):
DIFFERENTIAL EQUATIONS: Definition and formation of differential equations, differential equations of first order
and first degree in which variables are separable, homogeneous, reducible to homogeneous equations, linear equation form
or equation reducible to linear equation form. Linear differential equations with constant coefficients: Auxiliary equations
having different roots, equal roots, imaginary roots. Particular integrals
Unit- II ( 12 Hrs):
LAPLACE TRANSFORMS: Definition, transforms of elementary functions, properties of linearity and shifting, Inverse
laplace transforms, transforms of derivatives, solution of ordinary and simultaneous differential equations.
Unit- III ( 12 Hrs):
STATISTICS: No derivation of formula (application part), condensation of data collected, various forms of frequency
distribution, tabular presentation of data, structure of a table, simple table, complex table. Bar diagram, graphical
representation of frequency distribution, histogram, frequency polygon, cumulative frequency curve, some common types
of frequency distribution. Measure of central tendency : Calculation of arithmetic mean, geometric mean, median,
quartiles and mode.
Unit- IV ( 12 Hrs):
Measure of dispersion : Range, quartile deviation, mean deviation, standard deviation, coefficient of variation. Fitting of
curves using least square principle. Interpolation : Graphical method, curve fitting, Newton’s Gregory method, Newton-
Binomal method, Largranges method. Probability : Simple and compound events, mutually exclusive events, independent
events. Additive and multiplicative law of probability, use of binomial theorem, characteristics of binomial distribution,
fitting of binomial distribution and testing of goodness of fit. Normal distribution, characteristics of normal distribution,
fitting chi-square distribution – application of chi-square test of goodness of fit. Comparison of a number of frequency
distribution, finding association and relationship between attributes.
Unit- V ( 12 Hrs):
Calculation of coefficient of correlation (Karl Pearson’s formula), rank correlation coefficient, calculation of regression
coefficient, regression lines, test of significance of large samples. Significance test of sample mean, comparison of large
samples. Significance test for proportions. Significance test of difference between means of two samples – samples from
same population (Universe), sample from different population. Fiducial limits for unknown mean. Test of significance of
small samples : t-distribution, use of t-distribution to test the significance of the mean of the sample testing, the
significance of the difference between the two sample mean, paired samples when the size of sample same.
Books Recommended:
1. Integral Calculus by Gorakh Prasad, Pothishala Prakashan, Pvt. Ltd, Allahabad.
2. Laplace and Fourier Transforms by Goyal and Gupta, pragati prakashan, Meerut.
3. Fundamental of Mathematical statistics by ray and Sharma.
4. Fundamental of Mathematical statistics by Gupta and Kapoor.
22
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
Books Recommended:
1. Drake R.L. , Vogel W. , Mitchell AWM, “Anatomy for students” , Elsevier Publication
2. Tortora G.J. Derrockson B., “Principles of Anatomy and Physiology”, John Willey & Sons
3. Guyton A.C., Halt J.E. “Text Book of Medical Physiology” , Harcourt India Pvt. Ltd.
4. Ross and Wilson “Anatomy and Physiology in Health and Illness” , Churchil Living Stone
5. C.C. Chaterjee, “ Human Physiology, Vol. – I , Medical Allied Agencies, Calcutta
23
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 2103 Pharmacognosy and Phytochemistry-I (T) 4 0 4
Hours Per Week
Books Recommended:
1. Text Book of Pharmacognosy – C.S. Shah & J. S. Quadry
2. Text Book of Pharmacognosy – T. E. Wallis
3. Pharmacognosy – Trease & Evans
4. Pharmacognosy – Brady & Taylor
5. Text Book of Pharmacognosy – V. K. Kapoor & S.S. Handa
6. Pharmacognosy – C. K. Kokate, A.P. Purohit and S.B. Gokhale
24
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
.Course Course L T Credits
Code
PHSC 2104 Pharmaceutical Chemistry-III (Organic Chemistry-II) (T) 3 0 3
Hours Per Week
Books Recommended:
1. R.T. Morrison and R.N. Boyd: Organic Chemistry, Allyn and Bacon Inc., Boston (USA).
2. I.L. Finar: Organic Chemistry, Vol. I & II, ELBS and Longman Group Ltd., London.
3. L.M. Atherden: Bentley and Driver's-Textbookof Pharmaceutical Chemistry, Oxford University Press, Delhi
4. F.G. Mann & B.C. Saunders: Practical Organic Chemistry, Longman, London and New York.
5. S.N. Pandeya: A Textbook of Pharmaceutical Chemistry (Heterocyclics & Biomolecules) Vol-II, S.G.Publishers, Varanasi
25
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 2105 Pharmaceutical Analysis I (T) 4 0 4
Hours Per Week
Books Recommended:
1. J. Mendham, R.C. Denney, J.D. Barnes and M.J.K. Thomas. Vogel’s Text Book of Quantitative Chemical Analysis.
2. A.H. Beckett and I.B. Stenlake, Practical Pharmaceutical Chemistry. Part I & II. The Athlone Press, London
3. K.A. Connors. A Text Book of Pharmaceutical Analysis. Johan Wiley & Sons.
4. Pharmacopoeia of India.
26
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 2110 Environmental Studies (T) 3 3
Hours per week
Unit 2 : Natural Resources : Renewable and non-renewable resources : Natural resources and associated problems.
a) Forest resources : Use and over-exploitation, deforestation, case studies. Timber extraction, mining, dams and their effects on
forest and tribal people.
b) Water resources : Use and over-utilization of surface and ground water, floods, drought, conflicts over water, dams-benefits
and problems.
c) Mineral resources : Use and exploitation, environmental effects of extracting and using mineral resources, case studies.
d) Food resources : World food problems, changes caused by agriculture and overgrazing, effects of modern agriculture,
fertilizer-pesticide problems, water logging, salinity, case studies.
e) Energy resources : Growing energy needs, renewable and non renewable energy sources, use of alternate energy sources. Case
studies.
f) Land resources : Land as a resource, land degradation, man induced landslides, soil erosion and desertification.
• Role of an individual in conservation of natural resources.
• Equitable use of resoureces for sustainable lifestyles. (8 lectures)
Unit 3 : Ecosystems
• Concept of an ecosystem. • Structure and function of an ecosystem.
• Producers, consumers and decomposers. • Energy flow in the ecosystem.
• Ecological succession. • Food chains, food webs and ecological pyramids.
• Introduction, types, characteristic features, structure and function of the
following ecosystem :-
a. Forest ecosystem b. Grassland ecosystem c. Desert ecosystem
d. Aquatic ecosystems (ponds, streams, lakes, rivers, oceans, estuaries) (6 lectures)
Book recommended
Text book for environmental studies by Erach Bharucha
28
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Course P Credits
Code
PHSC 2106 Human Anatomy, Physiology And Health Education (P) 3 1
Hours per week
Books Recommended:
1. Semulingam and Prema Semulingam, “ Essential of medical Physiology” , Jaypee brothers, Medical Publishers Pvt. Ltd. , New Delhi
2. Goyal and Patel, “Practical Anatomy and Physiology”, B. S. Sah [Prakashan, Ahmedabad
29
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 2107 Pharmacognosy and Phytochemistry – I (P) 3 1
Hours per week
Books Recommended:
Synthesis, Purification, Characterisation (by using solubility, melting point, and percentage purity) of organic
compounds based on the theory like 2,4,6-trinitrophenol from phenol, Iodoform from ethyl alcohol, Phthalidimide from
phthalic anhydride, Aspirin, Phenyl urea, Flourescein, Methyl orange etc..
Books Recommended:
1. Vogel’s Text Book of practical Organic Chemistry, Longman, London. New York.
2. A.A. Siddiqui & Mohd. Ali: Practical Pharmaceutical Chemistry, New Delhi.
31
B.PHARM. – II SEMESTER
: w.e.f. session 2016-17
Course Code Course P T Credits
PHSC 2109 Pharmaceutical Analysis I (P) 3 0 4
Hours Per Week
The students should have a clear understanding of the principle and working of a typical analytical balance, the
requirements of a good balance, precautions to be taken during handling of a balance, methods of weighing and errors in
weighing sensitivity of a two pan, one pan and a top pan balance. The students should also be acquainted with the use of
appropriate apparatus for various analytical procedures.
Study of balances and its parts (both mechanical & electrical).
Calibration of glasswares and weights to be used narrating their importance.
Preparation and standardization of acids and bases.
Analysis of mixtures of carbonates.
Preparation, standardization and storage of KMnO4, Iodine, Bromine, Cerric ammonium sulphate .
Uses of the above mentioned chemicals for analysis of drugs.
Practicals involving:
1. Potassium permanganate, Iodine, Bromine, Cerric ammonium sulphate and Titanous chloride (Redox Titrations).
2. Argentimetric titration (Precipitation methods).
Books Recommended:
J. Mendham, R.C. Denney, J.D. Barnes and M.J.K. Thomas. Vogel’s Text Book of Quantitative Chemical Analysis.
A.H. Beckett and I.B. Stenlake, Practical Pharmaceutical Chemistry. Part I & II. The Athlone Press, London
K.A. Connors. A Text Book of Pharmaceutical Analysis. Johan Wiley & Sons.
Pharmacopoeia of India.
32
B.PHARM. – III SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 3101 Physical Pharmaceutics (T) 4 0 4
Hours Per Week
Physical Pharmaceutics (T)
Unit – I (12 Hrs):
State of matter: State of matter, gaseous state, liquid state, solid and crystalline state, liquid crystalline state, dielectric
constant, solubility of solid in liquid: ideal and non ideal solution, salvation and association in solution, factors influencing
solubility, phase equilibrium and phase rule (one component, two component system containing liquid phase and solid &
liquid phase), thermal analysis, Buffer equation and buffer capacity in general.
Kinetics and drug stability: Rate and order of reactions, factors affecting rate of reaction, decomposition and stabilization of
medicinal agents, kinetics in the solid state, accelerated stability analysis
Unit – II (12 Hrs):
Diffusion and Dissolution: Steady state diffusion, procedures and apparatus, dissolution and drug release, diffusion
principles in biologic systems, vapour sorption and transmission, thermodynamics of diffusion, diffusion and ecology.
Micromeritics: Particle size and size distribution, methods for determining particle size, particle shape and surface area,
methods for determining surface area, pore size, derived properties of powders.
Unit – III (12 Hrs):
Rheology: Introduction, newtonian system, Non Newtonian system, thixotropy, determination of rheologic properties,
viscoelasticity, psychorheology, applications to Pharmacy.
Surface and interfacial phenomena: Liquid interfaces, adsorption at liquid interfaces, adsorption at solid interfaces, electrical
properties of interfaces.
Colloids: Introduction, Types of colloidal systems, optical, kinetic and electric properties of colloids, solubilization.
Unit – IV (12 Hrs):
Coarse Dispersions: Suspensions, interfacial properties of suspended particles, settling in suspensions, Emulsions,
theories of emulsification, physical stability of emulsions, preservation of emulsions, rheologic properties of
emulsions, phase equilibria and emulsion formulation, special emulsion systems.
Complexation and Protein Binding: Metal complexes, organic molecular complexes, inclusion compounds, methods of
analysis, protein binding, complexation and drug action, crystalline structure of complexes, thermodynamic treatment of
stability constants.
Unit – V (12 Hrs):
Compaction and compression: Compression characteristics of powders and granules, physics of tablet compression,
measurement of punch forces, transmission of forces through powders, distribution of forces in powder mass, factors
affecting strength of tablets.
Crystallization: Introduction, Nucleation and crystal growth, crystal type, theory of crystallization, batch crystallizers,
simple vacuum crystallizers, prevention of crystals caking,
Books Recommended:
Physical Pharmacy - Martin, Swarbrick & Cammarata.
Physical Pharmaceutics - Schotton
Remington's Pharmaceutical Sciences.
An introduction to Chemical Engineering - Badger and Banchero.
Chemical Engineering - Richardson and Coulson.
Introduction to Unit Operation - McCabe and Smith.
Theory and Practice of Industrial Pharmacy-Lachman,Lieberman and Kanig
Bentley's Text Book of Pharmaceutics - Rowlin.
Moore W J. Physical Chemistry
M. E. Aulton: Pharmaceutics the science of deosafe form design, Churchill, Living Stone.
33
B.PHARM. – III SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 3102 CELL AND MOLECULAR BIOLOGY (T) 2 0 2
Hours Per Week
Proteins and amino acids: Isolation and classification of proteins, hydrolysis, fibrous and globular
proteins, classification, methods of synthesis and properties of amino acids, nucleoproteins and nucleic acids
and general knowledge of nitrogenous bases in nucleic acids, structure of nucleosides and nucleotides,
structure of nucleic acids.
Flavones & isoflavones, coumarines, porphyrines
Unit –IV (12 Hrs.)
Lipids fats oils and waxes,fatty acids: Characterization and their physico-chemical properties, general
knowledge of phospholipids ,lecithins, cephalines, sphingomyeline, glycolipids,lipoproteins.
Terpenes: Isolation, classification, general methods of determining structure with reference to citral,
carvone, thymol, menthol and camphor. An elementary treatment of rubber.
Unit –V (12 Hrs.)
Alkaloids: General methods of determining structure of alkaloids, classification with an acquaintance with
the structure of alkaloids of IP, structure elucidation of ephedrine, nicotine and xanthine derivatives like
caffeine, theobromine and theophylline.
Books Recommended:
Finar, I.L. Organic Chemistry, Vol.-I and II, ELBS/Longman.
Acheson, “An introduction to heterocyclic compounds”
Indian Pharmacopoeia.
Hendrikson, Organic Chemistry
35
Active, Passive immunization: Vaccines, types of Vaccines and principle involved, their
preparations, standardization and storage.
An introduction to Chemical Engineering – Badger W L and Banchero J T., McGraw Hill, New York
Chemical Engineering – Richardson J F. and Coulson J M. Asian Book Delhi.
Introduction to Unit 0peration - McCabe and Smith.
Theory and Practice of Industrial Pharmacy-Lachman,Lieberman and Kanig
Bentley's Text Book of Pharmaceutics - Rowlin.
6.Perry R H. Perry’s Chemical Engineering hand book, Tata Mc Graw Hills
7.Cooper and Gunn tutorial Pharmacy, CBS Publication India
37
B.PHARM. – III SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 3106 Physical Pharmaceutics (P) 3 1
Hours per week
Books Recommended:
Physical Pharmacy - Martin, Swarbrick & Cammarata.
Physical Pharmaceutics - Schotton
Remington's Pharmaceutical Sciences.
An introduction to Chemical Engineering - Badger and Banchero.
Chemical Engineering - Richardson and Coulson.
Introduction to Unit Operation - McCabe and Smith.
Theory and Practice of Industrial Pharmacy-Lachman,Lieberman and Kanig
Bentley's Text Book of Pharmaceutics - Rowlin.
38
B.PHARM. – III SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
Pharmaceutical Chemistry-IV (Chemistry
PHSC 3107 3 1
Of Natural Product) (P)
Hours per week
Books Recommended:
Finar, I.L. Organic Chemistry, Vol.-I and II, ELBS/Longman.
Acheson, “An introduction to heterocyclic compounds”
Indian Pharmacopoeia.
Hendrikson, Organic Chemistry
39
B.PHARM. – III SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 3108 Pharmaceutical Microbilogy (P) 3 1
Hours per week
Experiments devised to prepare various types of culture media, sub-culturing of common aerobic and anaerobic bacteria,
fungus, and yeast, various staining methods, various methods of isolation and identification of microbes, sterilization
techniques and their validation evaluation of antiseptics and disinfectants, testing the sterility of pharmaceutical products as
Books Recommended:
G. Gunnz & S.J. Carter “Cooper & Gunn’s Tutorial Pharmacy”, 6 th ed., Pitman Medical Publishing Co., London 1972.
W.B. Hugo and A.D. Russell “Pharmaceutical Microbiology”, 4 th ed., Blackwell Scientific Publication, Oxford, 1987.
“Microbiology”- Davis, Dulbecco, Eisen.
“Remington’s Pharmaceutical Sciences” Gennaro A.R. Ed., 18th ed., Mack Publishing Co., Easton, Pa, USA, 1990.
L.M. Prescott, G.P. Jarly, D.A. Klein, “Microbiology” 2nd, ed. Wm. C. Brown Publishers, Oxford, 1993.
S.P. Vyas, V.K. Dixit,”Pharmaceutical Biotechnology“1st ed. CBS Publishers & Distributors, New Delhi, 1998.
N.K. Jain,”Pharmaceutical Microbiology” Vallabh Prakashan, Delhi.
K. Kieslich, Ed. “Biotechnology” vol. 6a, Verlag Chamie, Switzerland, 1984.
G. Reeves “Lecture Notes on Immunology” Blackwell Scientific Publication, Oxford, 1987.
Laboratory Manual of Bacteriology- Salle
40
Books Recommended:
Books Recommended:
C.C. Chatterjee. Human Physiology.
J.W. Kathleen, Ross and Wilson. Anatomy and Physiology in Health and Illness
G.J. Tortora and B. H. Derrickson. Principles of Anatomy and Physiology, 11th edition. 2004. John Wiley & Sons.
C. Arthur, M.D. Guyton, John E. Hall. Textbook of Medical Physiology.
G. Pocock and C.D. Richards. Human Physiology: The Basis of Medicine. 3 rd edition. 2004.
42
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 4102 Dosage Forms Design (T) 4 0 4
Hours Per Week
Unit – II (12Hrs):
Polymer sciences: Introduction, classification and pharmaceutical applications of polymers, Polymers as thickening
agents,
Preparing polymer solutions, Phase separation, Gel formation, Mechanical properties of polymeric films, Future trends in
pharmaceutical and other biomedical uses of polymers.
Good manufacturing practice for pharmaceuticals: Concept and need of GMP and GLP quidelines , elements of GMP,
Covering controls of area and processes and product, regulations related to GMP. Quality assurance and quality audit.
Books Recommended:
G. S. Banker and C. T. Rhodes. Modern Pharmaceutics. 4th edition. 2002. Maecell Dekker.
Syad Imtiaz Haider. Pharmaceutical Master Validation Plan. Special Indian edition. 2001, CRC Press.
P.P. Sharma. How to Pracitise GMPs. A plan for total quality control. 2 nd edition, Vandana Publication.
Sidney H. Willig, Murray M. Tuckerman and William S. Hitchings IV. Good Manufacturing Practices for Pharmaceutics: A Plan for
Total Quality Control. 2nd edition. Marcel Dekker.
A.R. Gennaro. Remington's Pharmaceutical Sciences. 18th edition. Mack Publishing Co. Pennsylvania, USA 1990.
Gilbert S. Banker and Cristopher T. Rhodes. Modern Pharmaceutics Drugs and Pharmaceutical Science. Series vol. 7. 1979. M&D
Inc. New York.
Leon Lachman. The Theory and Practice of Industrial Pharmacy. 2 nd edition, Indian Edition, 1976, K.M. Varghese Co., Bombay.
E.A. Rawlins. Bentley's Textbook of Pharmaceutics,, 8th edition, 1977, Bailliere Tindall, London, England
S.J. Carter-Cooper and Gun's Tutorial Pharmacy, VI Ed., 1072, Pitman Medical.
Pharmacopoeia of India, 1996, Controller of Publication. Ministry of Health and Family Welfare, Govt. of India. Delhi,
British Pharmacopoeia, 1994.
A. Martin, J. Swarbrick and A. Cammarata. Physical Pharmacy. Lea and Febiger, Philadelphia
D.H. Shah. SOP guidelines. 2004. Published by Business Horizones.
43
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 4103 Pharmaceutical Biotechnology (T) 4 0 4
Hours Per Week
Books Recommended:
S.P. Vyas and A. Mehta. Cell and Molecular Biology. CBS Publishers, New Delhi
S.P. Vyas and V.K. Dixit. Pharmaceutical Biotechnology. CBS Publishers, New Delhi.
Elliott, W.C. & and Elliott, D.C. Biochemistry and Molecular Biology, 2nd edition, 2001. Oxford University Press
B.R. Glick and J.J. Pasternak. Molecular Biotechnology: Principles and Applications of Recombinant DNA: (1998) ASM Press
Washington D.C.
S.B. Primrose. Molecular Biotechnology. 2nd edition, 1999. Blackwell Scientific Publication.
Medical Immunology. 10th edition, International edition, Lange, McGraw-Hill Companies, ISBN- New Delhi.
Oskar Zaborsky. Immobilized Enzymes. 1973. CRC Press, Degraland, Ohio.
S.P. Vyas and H.D. Kumar advances in pharmaceutical biotechnology CBS Publishers, New Delhi
44
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 4104 Pharmacognosy and Phytochemistry-II (T) 4 0 4
Hours Per Week
Unit-II (12Hrs.):
Resins: classification and medicinal importance.
Study of some important resin containing drugs
Colophony, Podophyllum, Jalap, Canabis, Capsicum, Myrrh, Asafoetida, Balsam of Tolu,
Balsam of Peru, Benzoin, Turmeric, Ginger etc.
Tannins Classification, chemistry, uses and medicinal significance.
Important drugs of this category like Gambir, Black Catechu, Pale Catechu, Myrobalan etc.
Unit-III (12Hrs.):
Proteins and enzymes:
Sources, Preparation, Identification test, Chemical nature, and uses of papain, pepsin,
pancreatin, urokinase, diastase, trypsin, penicillinase, hyaluronidase.
Marine Pharmacognosy: Study of novel agents from marine sources
Unit-IV (12Hrs.):
Quality Control and Standardization:
Introduction, classification,and study of different chromatography methods and their methods and their applications in evaluation
of herbal drugs.
Extractive values, Ash values, Chromatographic techniques (TLC, HPTLC, HPLC), Concept of marker compounds
WHO Guidelines for rational use of herbal drugs
Unit V (12Hrs.):
Herbal constituents as health foods and cosmetic ingredients, Natural allergens, photosensitizing agents, Fungal and mushroom
toxins, poisonous plants
Chemistry and biogenesis of medicinally important lignans, quassinoids and flavonoids
Concept of synergy in herbs
Radio Tracer Techniques and their utilization in elucidation of biosynthetic pathways in plants
Books Recommended
Pharmacognosy: Trease and Evans
Pharmacognosy: Tyler and Brady
Pharmacognosy – C. K. Kokate, A.P. Purohit and S.B. Gokhale
A Text Book of Pharmacognosy – C.S. Shah & J. S. Quadry
A Text Book of Pharmacognosy – T. E. Wallis
Text Book of Pharmacognosy – V. K. Kapoor & S.S. Handa
Pharmacopoeia of India.
45
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
Pharmacy Practice (Dispensing and
PHSC 4105 4 0 4
Community Pharmacy) (T)
Hours Per Week
Books Recommended:
Hoover ‘s Dispensing of medication. Mack Publishing.
Joseph Barnett Sprowls. Prescription Pharmacy.
S. J. Carter. Cooper and Gunn's Dispensing for Pharmaceutical Students: Carter. 11th edition. CBS Publishers.
N.K. Jain and S.N. Sharma. The Concise Pharmaceutical Dispensing. Vallabh Prakashan, Delhi.
N.K. Jain. Health Education and Community Pharmacy. CBS Publishers.
46
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course P T Credits
Human Physiology and
PHSC 4106 Pathophysiology of Common 3 0 1
Diseases (Practical) (P)
Hours Per Week
Books Recommended:
Shukant R. Apte. Experimental Physiology.
Ramesh K. Goyal, Natyar M. Patel and Shailesh A. Shah. Practical Anatomy, Physiology and Biochemistry.
Sir John Y. Dacie and S. M. Lewis. Practical Haematology.
47
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course P T Credits
PHSC 4107 Dosage Form Design (Practical) (P) 3 0 1
Hours Per Week
Books Recommended:
G. S. Banker and C. T. Rhodes. Modern Pharmaceutics. 4th edition. 2002. Maecell Dekker.
P.P. Sharma. How to Pracitise GMPs. A plan for total quality control. 2 nd edition, Vandana Publication.
A.R. Gennaro. Remington's Pharmaceutical Sciences. 18th edition. Mack Publishing Co. Pennsylvania, USA 1990.
Gilbert S. Banker and Cristopher T. Rhodes. Modern Pharmaceutics Drugs and Pharmaceutical Science. Series vol. 7. 1979. M&D
Inc. New York.
Leon Lachman. The Theory and Practice of Industrial Pharmacy. 2nd edition, Indian Edition, 1976, K.M. Varghese Co., Bombay.
E.A. Rawlins. Bentley's Textbook of Pharmaceutics,, 8th edition, 1977, Bailliere Tindall, London, England
S.J. Carter-Cooper and Gun's Tutorial Pharmacy, VI Ed., 1072, Pitman Medical.
Pharmacopoeia of India, 1996, Controller of Publication. Ministry of Health and Family Welfare, Govt. of India. Delhi,
British Pharmacopoeia, 1994.
10.A. Martin, J. Swarbrick and A. Cammarata. Physical Pharmacy. Lea and Febiger, Philadelphia
48
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course P T Credits
PHSC 4108 Pharmaceutical Biotechnology (P) 3 0 1
Hours Per Week
Books Recommended:
Methods in biotechnology and Bioengineering, By Vyas, S.P. and Kohli, D.V. CBS Publishers and Distributors, New Delhi.
Laboratory Manual in Biochemistry By Jayaraman, J. New Age International Publishers, New Delhi.
Pharmaceutical Biotechnology, Vyas S. P. and Dixit V. K. CBS Publishers and Distributors, New Delhi.
49
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 4109 Pharmacognosy And Phytochemistry- II (P) 3 1
Hours per week
1. Identification and Evaluation of Representative Pharmacopia Drugs belonging to categories mention in theory in
whole and powdered form by Morphology and Microscopy.
2. Phytochemical test for the crude drugs in mentioned in theory.
3. Extraction and isolation of important phytoconstituents including caffeine, piperine, solaneceous alkaloids,
podophyllotoxin,sennosides, glycyrrhizine.
4. Visit of Medicinal Plant Garden and preparation of report.
5. Study of Drugs of Herbal Museum.
Books Recommended:
Practical Pharmacognosy: C.K. Kokate and Purohit
Evaluation of Phytopharmaceuticals : Turner
Pharmacopia of India
Pharmacognosy: Trease and Evans
Pharmacognosy: Tyler and Brady
A Text Book of Pharmacognosy – C.S. Shah & J. S. Quadry
A Text Book of Pharmacognosy – T. E. Wallis
Text Book of Pharmacognosy – V. K. Kapoor & S.S. Handa
50
B.PHARM. – IV SEMESTER
: w.e.f. session 2016-17
Course Code Course P T Credits
Pharmacy Practice
PHSC 4110 (Dispensing and Community 3 0 1
Pharmacy) (P)
Hours Per Week
Practice in Dispensing of not less then 100 prescriptions comprising of Solutions, Mixtures, Powders, Tablets, Capsules,
Lozenges, Ointments, Creams, Pastes, Jellies, Suppositories, Suspensions, Emulsions, Sprays, Inhalations, Paints,
Incompatibilities.
Books Recommended:
Hoover’s Dispensing of medication. Mack Publishing.
Joseph Barnett Sprowls. Prescription Pharmacy.
S.J. Carter. Cooper and Gunn's Dispensing for Pharmaceutical Students: Carter. 11th edition. CBS Publishers.
N.K. Jain and S.N. Sharma. The Concise Pharmaceutical Dispensing. Vallabh Prakashan, Delhi.
N.K. Jain. Health Education and Community Pharmacy. CBS Publishers.
51
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 5101 Cosmetic Technology (T) 4 0 4
Hours Per Week
(Hint for Unit – III to V) Formulation, manufacturing and equipments used for the following types of cosmetic preparations.
Unit-III (12 Hrs.):
Skin creams and lotions, classification of skin creams, cold, vanishing, all purpose and emollient creams, cleansing
creams, foundation creams, hand creams, protective and barrier creams.
Books Recommended
J.C. Mac Chesney "Packaging of Cosmetics and Toiletries" Newness-Butterworth, London, 1974.
M.S. Balsam & E. Sagarin "Cosmetics and Toiletries' 2nd ed. vol. 1-3, John Wiley and Sons, New York, 1974.
Sagarin- Cosmetic Science and Technology, vol. 1-3, 2nd ed., 1974.
J.S. Jellinek - Formulation and Function of Cosmetics, 1970.
G. S. Banker and C. T. Rhodes: Modern Pharmaceutics, Second Edition, Volume 40, Marcel Dekker, Inc., New York, 1990.
L. Lachman, H. A. Lieberman and J. L. Kaing: The Theory and practice of Industrial Pharmacy, Vargheese Publishing
House, Mumbai, 1987.
M. E. Aulton: Pharmaceutics, Science of Dosage Form Design.
E.A. Rawlins: Bentley’s Textbook of Pharmaceutics, University Printing House, Oxford, 1988.
D.F. Williams and W.H. Schmitt: Chemistry and Technology of the cosmetics and Toileteries Industry.
W.A. Poucher: Perfumes, Cosmetics and Soaps Vol. I, II and III Chapman and Hall London.
52
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Biochemistry (T)
Unit-I (12 Hrs.):
Biochemistry and its importance in Pharmaceutical Sciences.
Biochemical organization of the cell, production of cell energy, ATP and its biological significance. biochemical importance of
colloidal systems, Donnan effect.
Unit-II (12 Hrs.):
Enzymes: Classification, nomenclature, factors affecting enzyme action, enzyme kinetics, mode and mechanism of enzyme action
and inhibition, isozymes and their importance in diagnosis.
Vitamins as co-enzymes and their significance, metals as co-factors.
Carbohydrate Metabolism: Classification, glycolysis, citric acid cycle, glycogenesis and glycogenolysis. hexose monophosphate
shunt, uronic acid pathway, blood sugar and its regulation.
Unit-III (12 Hrs.):
Lipid Metabolism: Oxidation of fatty acids, biosynthesis of fats, ketogenesis and ketosis. metabolism of cholesterol. essential
fatty acids and eicosanoids phospholipids, sphingolipids.
Biological oxidation and reduction, respiratory chain, oxidative phosphorylation. enzymes and co-enzymes of Bioredox system.
Unit-IV (12 Hrs.):
Metabolism of Amino Acids and Proteins: General biochemical reaction of amino acids like transamination, deamination and
decarboxylation. metabolism of sulphur containing amino acids, urea cycle, nitrogen balance, biosynthesis of bile salts and bile
pigments.
Metabolism of Nucleic Acids: Biosynthesis and catabolism of purines and pyrimidines containing nucleotides.
Unit-V (12 Hrs.):
Biosynthesis of DNA and its replication, mutation and repair mechanism.
An introduction to genetic engineering, biosynthesis of RNA, genetic code and protein synthesis.
Liver and kidney function tests of biochemical importance.
Detoxification mechanisms like oxidation, hydrolysis, reduction & conjugation.
Books Recommended
D.W. Martin, P.A. Mays and V.M. Redwell, Harpers Review of Biochemistry, Lunge Medical
Publication.
Harpers Review of Biochemistry, Langue Medical Publication.
A.L.Lehninger, Biochemistry, Worth Publisher Inc.
A.L.Lehninger, Principle of Biochemistry, CBS publishers and Distributors.
L. Striae, Biochemistry, W.H. Freeman & Co. San Francisco.
B.Harrow and A.Mazur, Text Book of Biochemistry,W.B.Saunders Co.Philadelphia.
Text book of Biochemistry - West and Todd.
Elements of Biochemistry-O.P.Agrawal, Goel Publishing,House, Meerut
53
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
Medicinal Chemistry I (T)
PHSC 5103 3 0 3
Hours Per Week
Unit –V (09Hrs.):
Oxytocics (including discussion on ergot alkaloids also) (ergometrine)
Antihistamines including discussion on sodium cromoglycate (mepyramine, diphenhydramine, chlorpheniramine,
promethazine)
NSAIDS includes anti-gout drugs also (Indomethacin, phenylbutazone, allopurinol, probenecid).
Books Recommended
Foye, W.C. “Principles of Medicinal Chemistry” Lea and Febiger, Philadelphia
Wilson and Giswold’s “Textbook of Organic, Medicinal and Pharmaceutical Chemistry” J. Lippincott Co., Philadelphia.
Burger’s Medicinal Chemistry, John Wiley and Sons, Newyark
Singh and Kapoor “A Text Book of Pharmaceutical and Medicinal Chemistry” Vallabh Prakashan, New Delhi.
54
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Pharmacology-I (T)
BOOKS RECOMMENDED
Barar F S K, Text Book of Pharmacology, Interprint, New Delhi.
Best and Taylor's Physiological Basis of Medical Practice, William & Wilkins, Baltimore.
Crossland J and Thomson J H., Essentials of Pharmacology, Harper and Row Publishers NY
Craig C R and Stitzel R R, Modern Pharmacology, Little Brown and Company, 1994.
Davidson's Principles and Practice of Medicine, ELBS/Churchill Living Stone.
DiFore Lea SHand Febiger, Atlas of Normal Histology, Philadelphia.
Ghosh M N., Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman, L E
Guyton A C, Hall JE., Textbook of Medical Physiology,WB Sannders Company.
Human Physiology, C C Chatterjee, Medical Allied Agency, Calcutta.
Human Physiology, Subhash Shalya, CBS Publishers & Distributors.
Kulkarni S.K., Handbook of Experimentals Pharmacology, Vallabh Prakashan Delhi.
Mycek M J, Gertner S Band Perper M M, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company, Philadelphia.
Paul L., Principles of Pharmacology, Chapman and Hall.
Rang MP, Dale MM, Riter lM., Pharmacology, Churchill Livingstone.
Tortora G J, and Anagnodokos N P, Principles of Anatomy and Physiology Harper & Row Publishers N. Y.
55
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 5105 Pharmacognosy and Phytochemistry-III (T) 3 0 3
Hours Per Week
Unit-I (9 Hrs.):
Systematic Study of Crude Drugs: Including synonyms, biological / geographical sources, identification, chemical constituents,
chemical tests, uses, adulteration and evaluation of glycosidal drugs of following groups: Anthraquinone glycosidal drugs:
Senna, Aloe, Rhubarb, Cascara etc.
Saponin glycosidal drugs: especially, Dioscorea, Solanum, Licorice, Senega, Ginseng.
Cyanogenetic glycosidal drugs: Wild Cherry.
Coumarins and Furanocoumarin glycosidal drugs including Psoralea.
Miscellaneous glycosidal drugs: Gentian, Quassia, and Saffron etc.
Unit-II (9 Hrs.):
Systematic Study of Crude Drugs: Including synonyms, biological / geographical sources, identification, chemical constituents,
chemical tests, uses, adulteration and evaluation of Alkaloidal drugs of following groups:
Indole alkaloidal drugs : especially Ergot, Nux-vomica, Rauwolfia, Catharanthus.
Isoquinoline alkaloidal drugs: including Ipecac, Opium, Curare.
Tropane alkaloidal drugs: Stramonium, Hyoscyamus, Datura, Belladonna, Duboisia etc.
Quinoline alkaloidal drugs: including Cinchona.
Pyridine alkaloidal drugs: especially Areca, Lobelia, Nicotiana.
Imidazole alkaloidal drugs: including Pilocarpus.
Quinazoline alkaloidal drugs: including Vasaka.
Steroidal alkaloidal drugs: especially Ashwagandha, Kurchi, Veratrum, Solanum.
Proto-alkaloidal drugs: Ephedra, Colchicum etc.
Terpenoid alkaloidal drugs: including Aconite.
Unit-III (9 Hrs.):
Phytochemical Screening:
Preparation of extracts, Phytochemical tests for detection of common plant constituents, Biosynthetic pathways for secondary
plant constituents, General principles of formation of primary and secondary plant metabolites. Biogenesis of medicinally
important glycosides, alkaloids, carbohydrates, lipids, volatile oils and steroids.
Unit-IV (9 Hrs.):
Utilization and production of phytoconstituents from aromatic and medicinal plants: Isolation of the following phyto-
constituents (including industrial methods):
Morphine, Quinine, Reserpine, Sennosides, Digitalis glycosides, Diosgenin, Menthol, Thymol, Rutin, Psoralen.
Unit-V (9 Hrs.):
Classification and general treatment of alkaloids and glycosides of different categories including methods of isolations physico
chemical properties and chemical tests for identification.
Books Recommended:
Pharmacognosy: Trease and Evans
Pharmacognosy: Tyler and Brady
Pharmacognosy – C. K. Kokate, A.P. Purohit and S.B. Gokhale
A Text Book of Pharmacognosy – C.S. Shah & J. S. Quadry
A Text Book of Pharmacognosy – T. E. Wallis
Text Book of Pharmacognosy – V. K. Kapoor & S.S. Handa
Pharmacopia of India
56
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
Cosmetic Technology (P)
PHSC 5106 3 0 1
Hours Per Week
Books Recommended
E. Sagarin- Cosmetic Science and Technology, vol. 1-3, 2nd ed., 1974.
B. M. Mittal. Textbook of Pharmaceutical formulation.
W. A. Poucher: Perfumes, Cosmetics and Soaps Vol. I, II and III Chapman and Hall, London.
L. Lachman, H. A. Lieberman and J. L. Kaing: The Theory and practice of Industrial Pharmacy, Vargheese Publishing House,
Mumbai, 1987.
57
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Biochemistry (P)
1. Identification of carbohydrates (Scheme and identification) (glucose, fructose, lactos, mallose, sucrose)
2. Identification of proteins (Scheme and identification) (casein, albumin, gelatin, peptone)
3. Quantitative estimation of carbohydrates (any one method) DNA reagent, anthrone reagent
4. Quantitative estimation of proteins (any one method): biuret reagent, Lowry’s Reagent.
5. Quantitative analysis of Urine for
a) Normal Constituent
b) Abnormal constituents
6. Isolation and purification of enzymes.
Books Recommended
Pharmaceutical Biochemistry, Vyas & Kohli
Laboratory Manual in Biochemistry by J. Jayaraman, New Age Int. Pvt. Ltd. New Delhi.
Comprehensive Viva and Practical Biochemistry by A.C. Deb, New Central Book Agency, Calcutta.
58
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Books Recommended
A.A. Siddiqui & Mohd. Ali: Practical Pharmaceutical Chemistry, New Delhi.
Vogel’s Text Book of practical Organic Chemistry, Longman, London. New York.
F.G. Mann & B.C. Saunders: Practical Organic Chemistry, Longman, London and New York.
59
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 5109 Pharmacology-I (P) 3 0 1
Hours Per Week
Pharmacology-I (P)
1. Use of computer simulated CD’s or videocassettes for pharmacology practicals whenever possible.
2. Preparation of different solutions for experiments. Drug dilution, use of molar and w/v solutions in experimental
pharmacology. Common laboratory animals and anesthetics used in animal studies. Commonly used instruments in
experimental pharmacology.
3. Study of different routes of administrations in mice and rats. To study the effect of hepatic microsomal enzymes inhibitors
and induction on the pentobarbitone sleeping time in mice.
4. Effect of autonomic drugs on the gastrointestinal tract of rats or guinea pig.
Books Recommended
Kulkarni S.K., Handbook of Experimentals Pharmacology, Vallabh Prakashan Delhi.
Ghosh M N., Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
Mycek M J, Gertner S Band Perper M M, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company, Philadelphia.
60
B.PHARM. – V SEMESTER
: w.e.f. session 2016-17
Course Code Course P Credits
PHSC 5110 Pharmacognosy and Phytochemistry- III (P) 3 1
Hours per week
Books Recommended
V.E. Tyler, L.R. Brady & J.E. Robbers, Pharmacognosy (9 th Edition), K.M. Varghese Company, Bombay, India, 1988.
T.E. Wallis, Text Book of Pharmacognosy, J. & A. Churchill Ltd., London, 1967.
3.W.C. Evans, Trease and Evans, Pharmacognosy (14th Ed.), Gopsons Papers Limited, Noida, India, 1997.
Egon Stahl, Thin-Layer Chromatography, 2nd Ed., Springer Verlag, New York, 1969.
E.J. Shellard, Quantitative Paper and Thin Layer Chromatography, Academic Press, New York (Latest Edition).
C.K. Atal & B.M. Kapur, Cultivation and Utilization of Medicinal Plants, CSIR, India, 1982.
J.L. Real & E. Reinhard, Natural Products as Medicinal Agents, Hippocrates Verlag Shuttgart, 1981.
H. Wagner, S. Bladt, E.M. Zgainski, Plant Drug Analysis, Springer-Verlag, New York, 1984.
Yeshajahu Pomeranz and Clifton, E. Meloan, Food Analysis : Theory and Practice, The AVI Publishing Co. Inc., West Port, 1971.
Paul M. Dewick, Medicinal Natural Products: A Biosynthetic Approach, 2nd Edn. 2001, John Wiley & Sons.
Practical Pharmacognosy – C. K. Kokate, A.P. Purohit and S.B. Gokhale
61
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
S. No. Course Code Course Name L* T* Credits
01 PHSC 6101 Pharmaceutical Industrial Management (T) 3 0 3
Books Recommended
Vogel’s, Text Book of Quantitative Chemical Analysis.
Stahl: Thin Layer Chromatography Springer, Verlag, Berlin.
HHWillard, L.L. Merritt and J.A. Dean: Instrumental Methods of Analysis, Van Nostrand Reinhold, New York.
63
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 6103 Medicinal Chemistry-II (T) 3 0 3
Hours Per Week
a) Antitussives: Centrally acting antitussives, opium alkaloids and their modifications, synthetic antitussives,
peripherallu acting antitussives, expectorants
b) CNS stimulants: CNS stimulants of natural origin, synthetic CNS stimulants (nikethamide, methylxanthines and
modified methylxanthines (theophylline))
c) Psychopharmacological agents: Antipsychotics, phenothiazines (chlorpromazine, trifluperazine, butyrophenones,
miscellaneous), antidepressants- TCA (amitriptyline), MAO inhibitors, atypical antidepressants, antianxiety drugs-
meprobamate and related drugs, benzodianepines (diazepam)
64
Unit-V (09 Hrs.):
Books Recommended
Foye, W.C. “Principles of Medicinal Chemistry” Lea and Febiger, Philadelphia
Wilson and Giswold’s “Textbook of Organic, Medicinal and Pharmaceutical Chemistry” J. Lippincott Co., Philadelphia.
Burger’s Medicinal Chemistry, John Wiley and Sons, Newyark
Singh and Kapoor “A Text Book of Pharmaceutical and Medicinal Chemistry” Vallabh Prakashan, New Delhi.
65
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 6104 Pharmacology-II (T) 3 0 3
Hours Per Week
Pharmacology-II (T)
Unit-I (09 Hrs.):
Pharmacology of cardiovascular systems
a) Digitalis and cardiac glycosides.
b) Antihypertensive drugs.
c) Antianginal and vasodilator drugs, including calcium channel blockers and beta adrenergic antagonists.
d) Antiarrythmic drugs.
e) Antinyperlipidimic drugs
f) Drugs used in therapy of shock.
Unit-II (09 Hrs.):
Drugs acting on hemopoetic systems
a) Hematinics.
b) Anticoagulants, vitamin K and haemostatic agents.
c) Fibrinolyticand antiplatelet drugs.
d) Blood and plasma volume expanders.
Unit-III (09 Hrs.):
Drugs acting on urinary system
a) Fluid and electrolyte balance.
b) Physiology of urine formation, Diuretics.
Unit-IV (09 Hrs.):
Autacoids
a) Histamine, 5-HT and their antagonists.
b) Prostaglandins, thromboxanes and leukotrienes.
c) Pentagastrins, cholecytokinin, angiotensin, bradykinin and substance P.
Unit-V (09 Hrs.):
Drugs acting on respiratory system
a) Antiasthamatic drugs including bronchodilators.
b) Antitussive and expectorant.
c) Respiratory stimulants.
Books Recommended
Barar F S K, Text Book of Pharmacology, Interprint, New Delhi.
Best and Taylor's Physiological Basis of Medical Practice, William & Wilkins, Baltimore.
Crossland J and Thomson J H, Essentials of Pharmacology, Harper and Row Publishers NY
Craig C R and Stitzel R R, Modern Pharmacology, Little Brown and Company, 1994.
Davidson's Principles and Practice of Medicine, ELBS/Churchill Living Stone.
Di Fore Lea SH and Febiger, Atlas of Normal Histology, Philadelphia.
Ghosh MN, Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman,
Guyton A C, Hall JE, Textbook of Medical Physiology,WB Sannders Company.
Chatterjee C C, Human Physiology, Medical Allied Agency, Calcutta.
Shalya S, Human Physiology, CBS Publishers & Distributors.
Kulkarni SK, Handbook of Experimentals Pharmacology, Vallabh Prakashan Delhi.
Mycek MJ, Gertner SB and Perper MM, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company, Philadelphia.
Paul L, Principles of Pharmacology, Chapman and Hall.
Rang MP, Dale MM and Riter lM, Pharmacology, Churchill Livingstone.
Tortora GJ, and Anagnodokos NP, Principles of Anatomy and Physiology Harper & Row Publishers. NewYork
66
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
S. No. Course Code Course Name L* T* Credits
01 PHSC 6105 Pharmaceutical Manufacturing Technology (T) 4 0 4
Complexometric Titrations: Preparations and standardization of EDTA solution, pharmacopoeia assays like Milk of
Magnesia, Al(OH)3 gel, Calcium gluconate injection, HgCl2, etc., by complexometric titrations.
Miscellaneous Determinations: Assays involving titration with diazotization (Assay of sulfonamides), Estimation of
nitrogen content by Kjeldahl’s method, Moisture determination by Karl-Fischer titration.
TLC and paper chromatographic analysis of some pharmaceutical products.
Exercises based on acid bas titration in aqueous and non-aqueous media and oxidation-reduction titrations using
potentiometric technique, Determination of acid-base disassociation constants and plotting of titration curves using pH
meter.
Exercises involving polarimetry and conductometry.
Books Recommended
Beckette and Stenlake, Practical Pharmaceutical Chemistry, Vol. I & II The Athlone Press, London
Vogel’s “ Text Book of Quantitative Chemical Analysis”
E. Stahl: Thin Layer Chromatography Springer, Verlag, Berlin.
Willard HH, Merritt LL and Dean JA: Instrumental Methods of Analysis, Van Nostrand Reinhold,
New York.
68
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 6107 Medicinal Chemistry-II (P) 3 0 1
Hours Per Week
Books Recommended
Vogel’s Text Book of practical Organic Chemistry, Longman, London. New York.
Mann F.G. and Saunders BC, Practical Organic Chemistry, Longman, London and New York.
Pharmacopoeia of India, Govt. of India, Ministry of Health, Delhi.
Siddiqui AA and Mohd. Ali, Practical Pharmaceutical Chemistry, New Delhi.
69
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 6108 Pharmacology-II (P) 3 0 1
Hours Per Week
Pharmacology-II (P)
Books Recommended
Kulkarni SK, Handbook of Experimentals Pharmacology, Vallabh Prakashan Delhi.
Ghosh M N, Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
Mycek MJ, Gertner SB and Perper MM, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company, Philadelphia.
70
B.PHARM. – VI SEMESTER
: w.e.f. session 2016-17
Course
S. No. Course Name P* Credits
Code
Pharmaceutical Manufacturing Technology (P)
01 PHSC 6109 6 2
1) Experiments to illustrate preparation, stabilization, physical and biological evaluation of pharmaceutical products like
powders, capsules, tablets, parenterals, microencapsulation, surgical dressing etc.
2) Evaluation of materials used in pharmaceutical packaging.
Books Recommended
Gilbert S, Banker and Cristopher T. Rhodes - Modern Pharmaceutics Drugs and Pharmaceutical Science Series vol. 7, 1979, M&D
Inc. New York.
Lachman L, The Theory and Practice of Industrial Pharmacy, 2nd edition, Indian Edition, 1976, K.M.Varghese Co. Bombay.
Rawlins EA, Text Book of Pharmaceutics, 8th edition, 1977, Bailliere Tindall.
Remington's Pharmaceutical Science, 1985, Mack Publishing Co., Eastern, Pa.
Carter SJ, Cooper and Gun's Tutorial Pharmacy, VI Ed., 1072, Pitman Medical.
71
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 7101 Medicinal Chemistry-III (T) 3 0 3
Hours Per Week
Books Recommended
Foye, W.C., Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia.
Wolff , M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New York.
Hansch, C., Comprehensive Medicinal Chemistry, Pergarnon Press, Oxford.
Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Text Book of Organic,Medicinal and Pharmaceutical Chemistry, J.Lippincott
Co., Philadelphia.
Kar, A., Medicinal Chemistry, Willey Eastern Ltd., New Delhi.
Patrick, G., An Introduction to Medicinal Chemistry, Scientific Distributors, Mumbai.
Malone, Dyson and Purey, May’s Chemistry of Synthetic Drugs.
Singh H.K., Kapoor, V. K., Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, New Delhi
Thomas, G., Introduction to Medicinal Chemistry, CBS Publishers and Distributors, New Delhi.
73
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
Course Code Course L T Credits
PHSC 7102 Pharmaceutical Analysis III (T) 4 0 4
Hours Per Week
Pharmacology-III (T)
Unit-I (09 Hrs.):
Drugs acting on the Gastrointestinal Tract
Antacids, antisecretory and anti-ulcers drugs
Laxatives and antidiarrhoeal drugs
Appetite stimulants and suppressants
Emetics and anti-emetics
Unit-II (09 Hrs.):
Pharmacolgy of Endocrine system.
Hypothalamic and pituitary hormones.
Thyroid hormones and anti thyroid drugs, parathormone, calcitonin and vitamin D.
Insulin, oral hypoglycaemic agents and glucagons, Clinical management of diabetis
ACTH and corticosteroids.
Unit-III (09 Hrs.):
Androgens and anabolic steroids.
Estrogen, progesterone and oral contraceptive.
Drugs acting on the uterus.
Unit-IV (09 Hrs.):
Chemotherapy
General principles of chemotherapy.
Sulfonamides and cotrimoxazole.
Antibiotics – Penicillins, Cephalosporins, Chloramphenicol, Erythromycin, Quinolones and miscellaneous antibiotics.
Chemotherapy of tuberculosis, leprosy, fungal diseases, urinary tract infections and sexually transmitted diseases.
Unit-V (09 Hrs.):
Pathophysiology of various types of malignancies, Chemotherapy of malignancy and
immunosuppressive agents.
Definition of poison, general principles of treatment of poisoning with particular reference to barbiturates, opioids,
organophosphorous and atropine poisoning.
Heavy metals and heavy metal antagonists.
BOOKS RECOMMENDED
Barar F S K, Text Book of Pharmacology, Interprint, New Delhi.
Best and Taylor's Physiological Basis of Medical Practice, William & Wilkins, Baltimore.
Crossland J and Thomson J H., Essentials of Pharmacology, Harper and Row Publishers, NewYork
Craig C R and Stitzel R R, Modern Pharmacology, Little Brown and Company, 1994.
Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman, L E
Guyton A C, Hall JE., Textbook of Medical Physiology,WB Sannders Company.
Mycek M J, Gertner S Band Perper M M, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company,
Philadelphia.
Paul L., Principles of Pharmacology, Chapman and Hall.
Rang MP, Dale MM, Riter lM., Pharmacology, Churchill Livingstone.
Tortora G J, and Anagnodokos N P, Principles of Anatomy and Physiology Harper & Row Publishers N. Y.
75
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
S. No. Course Code Course Name L* T* Credits
01 PHSC 7104 Drug Legislation and Regulatory Affairs (T) 4 0 4
BOOKS RECOMMENDED
Books Recommended
Laurence, D R and Bennet P. N., Clinical Pharmacology, Churchill Livingstone.
Herfindal E T and Hirschman J L., Clinical Pharmacy and Therapeutics. Williams and Wilkins.
Remington’s Pharmaceutical Sciences.
W.E Hassan: Hospital Pharmacy.
Heifindal et al: Clinical Pharmacy & Therapeutics.
Allwood and Fell: Hospital Pharmacy.
Pratibha Nand and R.K. Khar: Hospital & Clinical Pharmacy.
77
BOOKS RECOMMENDED
Vogel’s Text Book of practical Organic Chemistry, Longman, London. New York.
Mann F.G. and Saunders BC, Practical Organic Chemistry, Longman, London and New York.
Pharmacopoeia of India, Govt. of India, Ministry of Health, Delhi.
Siddiqui AA and Mohd. Ali, Practical Pharmaceutical Chemistry, New Delhi.
78
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
Course Code Course Name P* Credits
PHSC 7107 Pharmaceutical Analysis III (P) 3 1
BOOKS RECOMMENDED
Pharmacopoeia of India, Govt. of India, Ministry of Health, Delhi.
Vogel’s Text Book of Micro and Semi Micro Qualitative Inorganic Analysis, Orient Longman, Hyderabad.
Beckett, A.H. and Stenlake, J.B., Practical Pharmaceutical Chemistry, The Athlone Press of the University of London.
79
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
Course
Course Name P* Credits
Code
PHSC 7108 Pharmacology III (P) 6 2
BOOKS RECOMMENDED
Kulkarni S.K., Handbook of Experimentals Pharmacology, Vallabh Prakashan Delhi.
Ghosh M N., Fundamentals of Experimental Pharmacology, Scientific Book Agency, Calcutta.
Mycek M J, Gertner S Band Perper M M, Pharmacology Lippincott's Illustrated Reviews, Lippincott Company, Philadelphia.
80
B.PHARM. – VII SEMESTER
: w.e.f. session 2016-17
Books Recommended
Books Recommended
Robinson, J.R. & Lee, V.H.I.,: Controlled and Novel Drug Delivery Marcel Dekker, New York and Basel.
Vyas S.P. & Khar R.K.: Controlled Drug Delivery, Vallabh Prakashan, New Delhi
Jain, N.K.: Controlled and Novel Drug Delivery, CBS, New Delhi.
Jain, N.K. Advances in Novel and Controlled Drug Delivery.
Chien, Y.W.: Novel Drug Delivery Systems, Marcel Dekker, New York and Basel.
Roseman, T.J.: Controlled Release Drug Delivery Ssytems, Marcel Dekker New York
Goldberg : Targeted Drugs.
Bruck, S.D., Controlled Drug Delivery, Vol. I & II.
Juliano, R.L. Drug Delivery Systems.
Review articles published in various journals.
Vyas S.P.Theory and practice in Novel Drug Delivery Systems, CBS, New Delhi
82
B.PHARM. – VIII SEMESTER
: w.e.f. session 2016-17
2) Passage of drug across GIT membrane. Mechanism, physico-chemical, biological and pharmaceutical factors affecting drug
absorption through GIT- Physicochemical, biological and dosage from related factors. Techniques for the GIT absorption
assessment.
Unit – II (12 Hrs):
3) Drug disposition: Distribution in blood, plasma -protein binding, application of drug protein binding.
4) Bioavailability and bioequivalence: Definitions, federal requirements, methods of determination of bioavailability using
blood and urinary excretion data. Protocol designs for bioavailability assessment. Methods for bioequivalence determination.
9) Dosage regimen: Dosage regimen adjustment in patients with and without renal failure.
Unit – V (12 Hrs):
10) Non-Compartmental Analysis: Statistical moments, Application, bioavailability determination.
11) Non-Linear Pharmacokinetics: Michaelis-Menten's kinetics, pharmacokinetic characteristics, In-vivo estimation of Km and
Vm, Unit impulse response. Application in bioavailability determination.
Books Recommended
Handbook of Basic Pharmacokinetics-Ritschel, W.A.,Drug Intelligence Publication, M Hamilton, 1977.
Fundamentals of Clinical Pharmacokinetics-Wagner,J.C.,Drug Intelligence Publication, M.Hamilton, 1975.
Remington's Pharmaceutical Sciences - Gennaro A.R., ed., 19th Edition, Mack Publishing Co., Easton, PA. 1995.
Clinical Pharmacokinetics - Rowland, M. & Tozer,N., 2nd,edition, Lea and Febiger, Philadelphia, 1989.
Pharmacokinetics-Gibaldi M. & Perrier, D., 2nd ed., Marcel Dekker, New York, 1982.
Pharmacokinetics for the Pharmaceutical Scientist-Wagner, J.C., Technomic Publishing AG, Switzerland, 1993.
Biopharmaceutics and Pharmacokinetics-Notari, R.E., 2nd ed., Marcel Dekker, New York, 1975.
83
Unit-II (9 Hrs.):
Ashok – (Saraca indica), Vidang (Embelia ribes), Lahsun (Garlic-Allium sativum), Malkangni (Celastrus paniculata),
Bhilwa (Semecarpus anacadium), Chirayata (Swertia chirata), Neem (Azadirachta indica), satavar (Aspargus racemosus),
Safed Musli (Chlorophytum borivalianum), Artemisia (Artemica spp), Thylophora (Thylophora indica), Morinda (Morinda
citrifolia), Chitrak (Plumbago zeylanicum), Haldi (Curcuma domestica), Tephrosia (Tephrosia purpurea), Bhui Amla (
Phyllanthus amarus), Shilajeet
Unit-III (9 Hrs.):
Introduction to dosage forms in Indian system od medicine with preparation and standardization of some important dosage
forms such as Asavas Arishtas, Avalehas and Churnas.
Unit-IV (9 Hrs.):
General method of extraction, isolation, identification and characterization of Phytoconstitutents of Carbohydrates, Alkaloids
Glycosides and Phenolic and Steroidal groups.
Unit-V (9 Hrs.):
An introduction to Tissue culture techniques with their scope as alternative sourse of Phyto-Pharmaceuticals.
An overview of plants as sourse of Bitters, Sweeteners, Colours, Flavoures, Carotinoids, Photosenstizing agents and Vaccines
Books Recommended
Trease, G.E. and Evans, W.C., Pharmacognosy, Bailliere Tindall, Eastbourne, U.K.
Tayler, V.C., Brady, L.R. and Robers, J.E., Pharmacognosy, Lea and Febiger, Philadelphia.
Shah, C.S. and Quadry, J.S., A text book of Pharmacognosy, B.S. Shah Publishers, Ahmedabad.
Kokate, C.K., Purohit, A.P. and Gokhale, S.B., Pharmacognosy, Nirali Prakashan, Pune.
Indian Pharmacopoeia, Ministry of Health and Family Welfare, Govt. of India, New Delhi.
Wallis, T.E., Text Book of Pharmacognosy, Jand A Churchill Limited, London
84
B.PHARM. – VIII SEMESTER
: w.e.f. session 2016-17
Course Code Course Name L* T* Credits
PHSC 8104 Elective (T) 4 0 4
Elective (T)
List of Elective Subjects:
I. GMP, Quality Assurance and Validation
II. Packaging Technology
III. Drug Design
IV. Drug Interaction
V. Nutraceuticals
VI. Herbal Drug Technology
Books Recommended
Robinson, J.R. & Lee, V.H.I.: Controlled and Novel Drug Delivery Marcel Dekker, New York and Basel.
Jain, N.K.: Controlled and Novel Drug Delivery,CBS, New Delhi.
Jain, N.K. Advances in Novel and Controlled Drug Delivery.
Chien, Y.W.: Novel Drug Delivery Systems, Marcel Dekker, New York and Basel.
Roseman, T.J.: Controlled Release Drug Delivery Ssytems, Marcel Dekker New, York
Goldberg : Targeted Drugs.
Bruck, S.D., Controlled Drug Delivery, Vol. I & II.
Juliano, R.L.: Drug Delivery Systems.
Vyas S.P.Theory and practice in Novel Drug Delivery Systems, CBS, New Delhi
88
B.PHARM. – VIII SEMESTER
: w.e.f. session 2016-17
Practicals based on ADME process, bioavailability, bioequivalance, protein binding, compartment models, Non-linear
pharmacokinetic analysis.
Books Recommended
Handbook of Basic Pharmacokinetics-Ritschel, W.A. Drug Intelligence Publication, M Hamilton, 1977.
Fundamentals of Clinical Pharmacokinetics- Wagner, J.C., Drug Intelligence Publication, M. Hamilton, 1975.
Remington's Pharmaceutical Sciences - Gennaro A.R., ed., 19th Edition, Mack Publishing Co., Easton, PA. 1995.
Clinical Pharmacokinetics - Rowland, M. & Tozer,N., 2nd,edition, Lea and Febiger, Philadelphia, 1989.
Pharmacokinetics-Gibaldi M. & Perrier, D., 2nd ed., Marcel Dekker, New York, 1982.
Pharmacokinetics for the Pharmaceutical Scientist-Wagner, J.C., Technomic Publishing AG, Switzerland, 1993.
Biopharmaceutics and Pharmacokinetics-Notari, R.E., 2nd ed., Marcel Dekker, New York, 1975.
89
B.PHARM. – VIII SEMESTER
: w.e.f. session 2016-17
Books Recommended