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Citation
WITNESS MAPANGA, Brendan Girdler-Brown, Elvira Singh, Tsungai Chipato. Treatment of
cervical cancer in HIV-seropositive women from developing countries: a systematic review.
PROSPERO 2018 CRD42018095707 Available from:
http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018095707
Review question
What are the treatment modalities that are being used to treat cervical cancer in HIV-seropositive women in
developing countries?
Searches
The search strategy of the online databases will be based on the criteria developed in the previous review
protocol by
Mapanga and colleagues. MEDLINE (1966–present) and Embase (1980–present) will be searched via the
OVID
interface. In addition, PubMed, Cochrane and CINAHL (1961–present) will be searched using a combination
of the following keywords: cervical cancer, treatment, developing countries (the geographical search concept
will be extended to include country names of developing countries), invasive cervical cancer,
HIV, management of cervical cancer, chemotherapy, surgery and radiation. In addition, health databases
which cover developing countries (3ie Systematic Reviews, WHO library and databases, World Bank
website) and databases and websites containing on-going research (such as WHO ICTRP
and ClinicalTrials.gov) will also be searched for relevant literature. Proximity operators, Boolean logic
operators and truncation commands will be used as suggested in the previous review protocol as well
as conducting preliminary search trials. To search for additional and relevant papers, reference and
citation tracking will be conducted
Participants/population
HIV-seropositive women
Intervention(s), exposure(s)
Cervical cancer treatment modalities such as chemotherapy, surgery etc
Comparator(s)/control
None
Context
Developing/ low-income countries
Primary outcome(s)
Existing treatment methods being used to treat cervical cancer in HIV-seropositive women in developing
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PROSPERO
International prospective register of systematic reviews
countries
Secondary outcome(s)
Existing treatment modalities that are affordable and feasible for developing countries
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PROSPERO
International prospective register of systematic reviews
Funding sources/sponsors
This review is part of Witness' PhD degree
Conflicts of interest
Language
(there is not an English language summary)
Country
South Africa, Zimbabwe
Published protocol
https://www.crd.york.ac.uk/PROSPEROFILES/95707_PROTOCOL_20180504.pdf
Stage of review
Review_Ongoing
Details of any existing review of the same topic by the same authors
Stage of review at time of this submission
Data extraction No No
Risk of bias (quality) assessment No No
Data analysis No No
Versions
25 May 2018
PROSPERO
This information has been provided by the named contact for this review. CRD has accepted this information in good
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PROSPERO
International prospective register of systematic reviews
faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration
record, any associated files or external websites.
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