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- makes up38/" of the nucleotidesin a sample of DNA from an organism.What percent of the
t- " -!Cqtosine
nucleotidesin this sample will be thymine?
@'z
B\2q
c) 31
D) 38
E) It cannot be determined from the information provided.
SHORT ANSWER. Write the word or phrase that best completes each statement or answers the question.
UseFigure16.1to answerthefollowingquestions.
/7-\ 1=_\
lap -lsp
]tiltltl lFocoe1|
|tql
hybridDNA
UBU
A. D. E.
\
Figure L6.1
spaceprobe returns with a culture of a microorganismfound on a distant planet. Analysis shows that it
-ZYA
is a carbon-basedlife form that has DNA. You grow the cells in 15Nmedium for severalgenerationsand
then transfer it to 14N medium. Which pattern in Figure 16.1would you expectif the DNA was replicatecl
in a conservativemanner?
MULTIPLE CHOICE. Choose the one alternative that best completes the statementor answers the question.
--af,Which enzymes catalyzethe elongation of a DNA strand in the 5'* 3' direction?
A) primase
!) OruaHgase
I DNA polymerases
D) topoisomerase
E) helicase
-.9fWtrirt''ofthefollowinghelptoholdtheDNAstrandsaPartwhiletheyarebeingreplicated?
A) helicase
n
t/
B) Iigase
C-)DNA PolYmerase
fi) single-stranded
binding proteins
v Y) exonuclease
5' refer to the
In DNA, the designations3' and bond'
to which phosphategrouPsmay
-.wr 6)carbon atoms.r i"t.Vttutse orpvrimidinebases'
utomson theringsof purine
H:ffi;;;;;;;;;"
fifth carbon atoms of deoxyribose'
A
t\
C) cross-linking of the third and
D)bondingbetweenpurinesanddeoxyriboseandbetweenpyrimidinesanddeoxyribose'
and thymine and between guanine
and cytosine'
E) bonds that form blt*een adenine
Bio202 Na *e Kt,llr * fir n 4 h fityr
Quiz - DNA replication 1,0120108
MULTIPLE CHOICE. Choosethe one alternative that best completesthe statementor answers the question.
\J1)WhichenzymeScatalvzeth"@.ofaDNAstrandinthe5'-3'direction?
A) primase
B) DNA ligase
C) DNA polymerases
D) topoisomerase
@n"ii.ur"
2) lCytosinemakes up 38% of the nucleotidesin a sample of DNA from an organism.What percent of the
iildlettiiGs in this sample will be thymine? t c1|
@;n \0 lb p
Ytz+ +-$gA --tV
c)31 ffi
D) 38
E) It cannot be determined from the information provided.
4) The problem of replicating the lagging strand of DNA-that is, adding basesin the 3' * 5' direction-
requires which of the following?
A) DNA ligase
B) RNA primers
c)Okazaki fragments
D ) A and B only
@ A, B, and C
6) All of the following are functions of PNA polvrlel€e jn DNA replication except
A) covalently adding nucleotidesto the new strands.
B) proofreading eachadded nucleotide for correctbasepairing.
A
!) replacing RNA primers with DNA.
initiating a polynucleotide strand.
Q)
/) In making a movie, sometimesan editor will cut out one pieceof film and insert another. This is analogous
to which of the following?
A) mismatchrepair
(9 excisionrepair
C) transformationrepair
D) recombinationalrepair
E) telomeraserepair
10) Which of the following help to hold the DNA strands apart while they are being replicated?
A) helicase
J B) ligase
C) DNA polymerase
@ single-strandedbinding proteins
E) exonuclease
..--F
:-'
Exam
M ULTIPLE CHOICE. Choose the one alternative that best completesthe statement or answers the question.
1) The 20 different amino acids found in polypeptides exhibit different chemicaland physical properties
becauseof different
A) carboxyl groups.
Blamino groups.
6$ia" .hlir,, in groups).
5 tertiarv structure.
E) Both A and B are correct.
RORO
H\lll lll
)N-C-C-N-C-C-O-H
H / tlt tltlt
l'l
lllrl
I'l'l
A. B. C. D. E. r'\
Figure5.6
2) At which bond would water need to be added to achievehydrolysis of the dipeptide shown, back to its
ponent amino acids?
B )B D)D E )E
9) lhe differencebetween the sugar in DNA and the sugar in RNA is that the sugar in DNA
(@ containsless oxygen.
Y) can form a double-stranded molecule.
C) has a six-membered ring of carbon and nitrogen atoms.
D) can attach to a phosphate,unlike the sugar in RNA.
E) is a six-carbon sugar and the sugar in RNA is a five-carbo
10) Which of the following are nitrogen basesof the purine type?
;\] cytosit e and guanine
(@,)guanineand adenine
! adenineand thyamine
D) thyamine and uridine
E) uridine and cytosine
Bio202 Name Sil\ \<r{Zr€a
Quiz - Protein synthesis 4/13/0s.
Qtg,kf, X_y.r_1.;;I gT?.T- tlia "
ilti;*#,i#H:'thoose theone
arternative
u"liii*tS.,H*;'#;gf"' K,/.tr
l;,lA;,htlX "r,i"fitfut
*|rc
'',ut
pathway:
referto thefollowingsimplemetabolic
followingquestions
enzyme a enzyme b
A +B _+C
1) A mutation results in a defective enzymg a. Which of the following would be a consequenceof that mutation?
A) an accumulation of C and no production of A and B
B) an accumulation of B and no production of A and C
C) an accumulation of B and C and no production of A
D) an accumulation of A and B and no production of C
8) A particular triplet of basesin the coding sequenceof DNA is AAA. The anticodon on the IRNA that binds the
mRNA codon is
A)TTr.
B)rruA. \
I
'@ruu
FD"o
Ef either UAA or TAA, depending on wobble in the first base.
10) From the following list, which is the first event in translation in eukaryotes?
A) covalent bonding between the first two amino acids
B) elongationof the polypeptide
of activated methionine-tRNA to AUG of the messengerRNAJ
$ fairinS
ding of the larger ribosomal subunit to smaller ribosome subunits
E) Both B and D occur simultaneously.
\
I
Bio2A2 ruu*"*ChOi€ Hpcr-l
Quiz -Protein synthesis2 nl26/a6
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
4) What type of bonding is responsible for maintaining the shape of the IRNA molecule?
A) covalent bonding between sulfur atoms
v) -p*"ryia"
/p*arogen
-
bondingbetweenaminoacids
bondingbetweenUur"puiri
E) van der Waals interactions between hydrogen atomf
/,/
5\ lPDYaf ribosomes
composedof?
andprotein
(r\
'l -l
/'P9#rRNA
-r4')mRNA, IRNA, rRNA, and protein
FI -l
its, each consisting of several proteins onl
->t subunits, each consisting of rRNA only
mRNA, rRNA, and protein
6) When a ribosome first attaches to an nRNA molecule, one IRNA binds to the ribosome. The IRNA that
recognizes the initiation codon binds to the
A) large ribosomal subunit only.
B) second IRNA before attaching to the ribosome. t
i7\t
site(Psite)of theribosomeonly.
fperytia"
acid site (A site) of the ribosome only.
/O}ardino
c-/il Both A and C are correct.
As a ribosome translocates along an mRNA molecule by one codon, which of the foilowing occurs?
A) The IRNA that was in the A site moves into the P site.
B) The IRNA that was in the P site moves into the A site.
C)The IRNA that was in the P site moves to the E site and isreleasefux
D)The tRNA that was in the A site departs from the ribosong".z/
h A and C are correct. i' ./
!)ioqdisjunction only
int only
nonsense only
B and D
\otir
Bio202 N^" &*,f7(,,/
Quiz - Protein synthesis November1,2004
--dULTIPLE CHOICE. Choosethe one alternative that best completesthe statementor answersthe question.
B)TCA.
C) UCA.
D) AGT.
E) either UCA or TCA, depending on wobble in the first base.
3) A particular eukaryotic protein is 300 amino acidslong. Which of the following could be the maximum number
of nucleotidesin the DNA that codesfor the mRNA {
c) 3 D) 100 E)300 0
A) 1,800
4) A portion of the geneticcode is UUU = phenylalanine,GCC = alanine,AAA = lysine, and CCC = Proline.
Assume the correct code placesthe amino acidsphenylalanine,alanine,and lysine in a protein (in that order).
Which of the followlng DNA sequenceswould substitute proline for alanine?
-'---
@B)AAT-CGG-TTT L4qr\- G,cc- AAA
C)AAA-CCC-TTT AAA - GGG-TT(
D)AAA-CCG-TTT
E)AAA-CGG-TTA
6) The genetic code is essentially the same for all organisms. From this, one can logically assume all of the
following except:
A) Codons usually translate into the same amino acids.
B) All organisms have a common ancestor.
C) A gene frorn an organism could theoretically be expressed by any other organism.
-vt L) A new form of life is discovered.It has a geneticcode much like that of organismson Earth exceptthat
there are five different DNA basesinstead of foq-rand the basesequencesare translated as doqblets instead
v of triplets. How many different amino acidscould be accommodatedby this genetic code?.
A)5 B )10 rc)zs D) 6 4 E)32
^
2) Which of the following is correct about a codon?It
A) consistsof two nulleotidesX
j) may code for the same amino acid as another codonl4'
!$ consistsof discreteamino acid regions.
D) catalyzesRNA synthesis.
E) is the basic unit of the geneticcode.{
6) A transcription unit that is 800nucleotideslong may use 1,200nucleotidesto make a protein consistingof
400 amino acids. This is best explained by the fact that
($ many noncoding nucleotides are present.
E) ther" is redundancy and ambiguity in the geneticcode.
C) many nucleotidesare neededto code for eachamino acid.
D) nucleotidesbreak off and are lost during the transcription process.
E) there are termination exonsnear the beginning of mRNA.
RNA ganscribed?
10) Whereis e:rkaryqfiEribogg!1al
A) the GolgiaPParatus r
r
I Blribosomes\ .!
V @ nucleoti
D) X chromosomes
E) prokaryotic cells onlY{
].1)F-romthefoIlowinglist,whicho,h@in$@ineukaryotes?
of the PolYPePtide
@ elongation AUG of the messengerRNA
B) basepairing or aciivatea methionine-tRNA to
ribosomesubunits
\.f
Bio202 Nu ." eKf ttif E rkr4hA ff']
Quiz - Generegulation 71107108 'r
MULTIPLECHOICE. Choosethe onealternativethat best completes the statement or answers the question.
4) Muscle cells and nerve cells in one speciesof animal owe their differencesin structure to
A) having different genes.
B) having different chromosomes.
using different geneticcodes.
;Q
IP) different genes.
"*pressing
E) having unique ribosomes.
5) In which of the following would you expectto find the most methylation of DNA?
A) tandem arrays for ribosomal genes
B) pseudogenes
G inactivated mammalian X chromosomes
D) globin genes
E) transposons
,Q
promoting the degradation of specificmRNAs.
1
-l
to receptorsand promoting transcription of certain regions of DNA.
Q)binding
E) promoting the formation of looped domains in certain regions of DNA.{
/
1.y1 All of the following aqepotential control meshaJrisfnsfor regulatign olgene exp{gssioo:irreukaryotic
/ organismsexcept
/ A) the degradation of mRNA.
B) the transport of mRNA from the nucleus.
,A'
(!) alternate splicing
P) transcription.
/ffpt of the above
Bio202 r r la mKet l li t B t n CJ h O r n
Quiz - 17I 24108
MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.