DRUG STUDY

Brand Name: Roxipan

Generic Name: oxytocin

NAME OF DRUG

Dose: 10 IU

Route: IM

Pharmacotherapeutic:

CLASSIFICATION OF DRUG Uterine smooth muscle stimulant

Clinical: Oxytocic agent

Activates receptors that trigger increase

in intracellular calcium levels in uterine

myofibrils; increases prostaglandin

MECHANISM OF ACTION
production.

Therapeutic Effect:

Stimulates uterine contractions.

Antepartum: Induction of labor in pts with

medical indication (e.g., at or near

INDICATIONS
term), to stimulate reinforcement of labor,

as adjunct in managing incomplete or

 inevitable abortion.

Postpartum: To produce uterine

contractions during third

stage of labor and to control postpartum

bleeding/hemorrhage.

Contraindicated for patients who are

hypersensitive to oxytocin. Adequate

uterine activity that fails to progress,

cephalopelvic disproportion, fetal distress

without imminent delivery, grand

multiparity, hyperactive or hypertonic

uterus, obstetric emergencies that favor

surgical intervention, prematurity,

CONTRAINDICATIONS unengaged fetal head, unfavorable fetal

position/presentation, when vaginal

delivery is contraindicated

(e.g., active genital herpes infection,

invasive cervical cancer, placenta previa,

cord presentation).

Cautions: Induction of labor should be for

medical, not elective, reasons. Generally

not recommended in fetal distress,

 hydramnios, partial placental previa,

predisposition to uterine rupture.

Occasional:

 Tachycardia

 Premature ventricular contractions

 Hypotension

 Nausea

SIDE EFFECTS  Vomiting

Rare:

 Nasal: Lacrimation/tearing, nasal

irritation, rhinorrhea

 Unexpected uterine

bleeding/contractions

 Hypertonicity may occur with

tearing of uterus, increased

ADVERSE EFFECTS bleeding, abruptio placentae (i.e.,

placental abruption),

cervical/vaginal lacerations.

 Ensure that the hands are

disinfected first and properly

NURSING RESPONSIBILITIES
gloved before administering the

drug to the patient.

  Check if the drug is in the proper

dose.

 After delivering the 1st baby, check

if there is a second baby before

administering oxytocin.

 Inform the patient about the drug

that is about to be given.

 Assess baselines for vital signs.

 Monitor the patient and the signs

and symptoms of any reaction.

 Monitor I&O.

 Monitor maternal electrolytes.

 Document the process as well as

the time and the date that the

medication was administered.

 If the patient feels nauseous and

about to vomit, offer ice chips.

Source: Kizior, R. & Hodgson, K. (2019). Saunders Nursing Drug Handbook 2019.

St. Louis, Missouri: Elsevier.