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Anti-Inflammatory Drugs in Dogs

Mechanism of Inflammation
Trauma (Mechanical, Chemical, Thermal)
Interleukin -1

Interleukin-6 Cytokines Cell Damage


Interleukin
Tumor Necrosis Factor α-1
(TNFα)
Interleukin Membrane phospholipids
-6
Tumor Phospholipase A2 Corticosteroids
Necrosis
Factor α

Arachidonic acid Platelet Activating Factor (PAF)


Cyclooxygenase-1 (COX-1) or
Cyclooxygenase-2 (COX-2) NSAIDs

Leukotrienes Prostaglandins G2 Oxygen radical

Thromboxane A2 Prostaglandins H2 Prostaglandins I2

Prostaglandins D2 Prostaglandins F2α

Prostaglandins E2

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