BDNF stroke exercise

NO Tahun Judul Referensi Sasaran Metode Hasil Diskusi

1 2016 Short-term (Vahlberg Untuk mengetahui Randomized controlled trial, 34 orang Terdapat peningkatan setelah 3
and long-term , Birgit et pengaruh progressive (76% male; 65–85 years) kelompok intervensi PRB exercises bulan pada tingkat
effects of a al, 2016) resistance and balance 2x/minggu selama 3 bulan dan kelompok kontrol. Dilakukan keseimbangan, kemampuan
progressive (PRB) exercises pemeriksaan (Berg Balance Scale, 0–56 points) and mobility berjalan, dan kemampuan
resistance DISABILI terhadap kemampuan (Short Physical Performance, 0–12 points). Pemeriksaan aktivitas fisik.
and balance TY AND fisik pasien stroke. lainnya yaitu 10 m comfortable walking speed, physical
exercise REHABIL activity levels, health-related quality of life,
program in ITATION depression and fall-related self-efficacy.
individuals J.
with chronic
strok
2 2016 Decreased (Gabriella Brain-derived 17 pasien stroke kronik dengan kelompok kontrol. Dilakukan Subjects with chronic Chronic post-stroke subjects
Brain-Derived et al, neurotrophic pemeriksaan fisik (berat badan, tinggi badan, indeks massa hemiparesis presented a presented a decrease in BDNF
Neurotrophic 2016) factor (BDNF) tubuh) dan pemeriksaan SS-QOL. Pada hari yang sama decrease in BDNF serum serum concentrations, without a
Factor Serum berperan dalam dilakukan pengambilan sampel darah vena pada kedua compared with healthy subjects correlation with post-stroke time,
Concentration Journal of pemulihan kelompok. Kadar serum BDNF diukur dengan enzyme-linked (P < .01). There was no age, and quality of life.
s in Chronic Stroke sensorimotor immunosorbent assay. correlation between BDNF
Post-Stroke and pascastroke. Penelitian serum levels with post-stroke
Subjects Cerebrov ini untuk mengetahui time, age or quality of life,
ascular kadar BDNF serum mobility, and the upper
Diseases pada pasien stroke extremity motor function
kronik dan fungsi (P > .05). BDNF concentrations
motorik berdasarkan are related to structural and
Stroke Specific Quality functional recovery after stroke;
of Life Scale (SS- thus, this reduction is important
QOL). to understand the rehabilitation
process more clearly. However,
more studies are needed
considering the genetic
variations and other tools to
assess motor impairment and
functional independence.
3 2019 Plasma (Mourao, Brain-derived Patients in the acute phase of ischemic stroke were evaluated Patients who were discharged BDNF levels were associated with
Levels of Aline neurotrophic with the following clinical tools: National Institutes of Health after 10 days had worse clinical clinical prognosis in the acute phase
Brain-Derived Mansueto factor (BDNF) is Stroke Scale, modified Rankin scale, Gugging Swallowing outcomes and higher levels of of ischemic stroke.
 Neurotrophic et al, a neurotrophin involved Screen and Alberta Stroke Program Early CT Score. Blood BDNF since admission. There
Factor are 2019) in neuronal survival, samples were collected at 3 different moments of hospital was correlation between BDNF
Associated differentiation, and stay. BDNF was measured through enzyme-linked levels and clinical parameters.
with Journal of maturation. To immunosorbent assay.
Prognosis in Stroke evaluate the levels
the Acute and of BDNF in the acute
Phase of Cerebrov phase of stroke and
Ischemic ascular their potential
Stroke Diseases association with
neurological
impairment.
4 2014 Virtual Reality (McEwen, Exercise using virtual blinded randomized controlled trial studying 59 stroke Confidence intervals and effect This VR exercise intervention for
Exercise Daniel et reality (VR) has survivors on an inpatient stroke rehabilitation unit was sizes favored the treatment inpatient stroke rehabilitation
Improves al et al, improved balance in performed. The treatment group (n=30) received standard group on the Timed Up and Go improved mobility-related outcomes.
Mobility After 2014) adults with traumatic stroke rehabilitation therapy plus a program of VR exercises and the Two-Minute Future
Stroke brain injury that challenged balance (eg, soccer goaltending, Walk Test, with both groups studies could include nonambulatory
An Inpatient American and community- snowboarding) performed while standing. The control group meeting minimal clinical participants as well as the
Randomized Heart dwelling older adults. (n=29) important differences after implementation strategies for the
Controlled Associati Rigorous randomized received standard stroke rehabilitation therapy plus exposure training. More individuals in the clinical use of VR.
Trial on studies regarding its to identical VR environments but whose games did not treatment group than in the
Journals efficacy, safety, and challenge balance (performed in sitting). VR training consisted control group showed reduced
applicability with of 10 to 12 thirty-minute daily sessions for a 3-week impairment in the lower
individuals after stroke period. Objective outcome measures of balance and mobility extremity as measured by the
are lacking. The were assessed before, immediately after, and 1 month after Chedoke
purpose of this study training. McMaster Leg domain (P=0.04)
was to determine immediately after training.
whether an adjunct VR
therapy improves
balance, mobility, and
gait in stroke
rehabilitation
inpatients.
5 2019 Aerobic ( Oliveira, investigate the efficacy This is a randomized controlled trial. Chronic stroke patients The findings of this trial have Neuroinflammation is an important
Training Daniela of moderate- will be randomized to an experimental or control group, and part of stroke pathophysiology and
Efficacy in Matos intensity treadmill will receive group interventions three times per week, over 12 the potential to provide has both detrimental and beneficial
Inflammation, Garcia, et exercise in weeks. The experimental group will receive moderate- important insights regarding the effects after stroke. Besides that the
Neurotrophins al. 2019) changing inflammatory intensity (60%-80% of maximum heart rate reserve) treadmill enhancement
effects of an aerobic physical
, and Function mediators, interleukin- exercise. Control group will perform walking training on the of neurotrophins seems to be
in Chronic Journal of 6(IL-6), soluble tumor ground (<40% of maximum heart rate reserve). Primary program in the inflammatory related to improvements in stroke
Stroke Stroke necrosis factor outcomes include IL-6, sTNFRI, sTNFRII, IL-10, process and in the neuronal recovery. Evidences suggest that
Persons: A and receptors I and II and BDNF levels. Secondary outcomes include mobility and plasticity in stroke persons and exercise plays a role in modulating
Randomized Cerebrov (sTNFRI, exercise capacity. Outcomes will be measured at baseline, anti-inflammatory and neurotrophic
Controlled ascular sTNFRII), interleukin- postintervention, and at the 4-week follow-up. its impact on mobility and effects. However, little is known
Trial Protocol Diseases 10 (IL-10), and brain- exercise capacity. about its impact in stroke survivors,
derived neurotrophic mainly in chronic stroke.
factor (BDNF) levels in
chronic stroke patients.
The secondary
objective is to
investigate the effects
of training in improve
mobility and exercise
capacity.