Metabolic Profiles of Rehospitalized Patients with Chronic Heart

Failure at National Cardiac Center Harapan Kita

Puspita S Bustanul, Dewi H Suprobo, Ade Widyastuti, Bambang B Siswanto, Nani

Hersunarti

BACKGROUND: The incidence of rehospitalization in patients with chronic heart

failure ranged from 23% to 50% annually. One of the factors that influenced the
rehospitalization in those patients with chronic heart failure was the management of
cardiovascular risk factors. Metabolic syndrome was associated with increased
cardiovascular risk factors. A way to assess for metabolic syndrome was from
metabolic profiles of these patients. Knowing the metabolic profiles in rehospitalized
patients with chronic heart failure could assist the clinician in managing the risk
factors that may affect the incidence of rehospitalization in patients with chronic heart
failure and metabolic syndrome.

AIM: To describe the metabolic profiles in rehospitalized patients with chronic heart
failure at National Cardiac Center Harapan Kita from January 1 st 2009 to December
31st 2009.

METHODS AND RESULTS: Retrospective study was conducted for 96 patients with
chronic heart failure whom were discharged from National Cardiac Center Harapan
Kita and rehospitalized within 6 months after previous discharge, from January
1st2009 to December 31st 2009. The modified NCEP ATP III (2005) criteria for
metabolic syndrome was used to assess metabolic factors, including BMI (body mass
index), SBP (Systolic Blood Pressure), DBP (Diastolic Blood Pressure), HDL
cholesterol, triglycerides, and fasting blood sugar (FBS). Metabolic syndrome was
diagnosed if the patient meets 3 of 5 factors : BMI ≥23 kg/m2, SBP ≥ 130 mmHg or
DBP ≥ 85 mm Hg, HDL <40 mg / dl for men, HDL <50 mg / dl for women,
triglycerides ≥150 mg/dl, and fasting blood sugar ≥ 100 mg / dl. Samples were taken
consecutively and analyzed descriptively. In this study, 74 (77.1%) patients were male
and 22 (22.9%) patients were female with age groups for male ≥ 40 years old were 68
(91,9%) patients and female ≥ 50 years old were 16 (72,7%) patients. The
rehospitalized patients with BMI ≥ 23 kg/m2 were 54 (56.3%) patients. There were 64
(66.7%) patients with SBP < 130 mmHg, and 77 (80.2%) patients with DBP < 85
mmHg. Male patients with HDL <40 mg / dl were 45 (60.8%) patients, and female
patients with HDL <50 mg / dl were 16 (72.7%) patients. Patients with triglyceride
levels <150 mg / dl were 75 (78.1%) patients. Fasting blood sugar ≥ 100 mg / dl was
found in 54 (56.2%) patients. From these data, metabolic syndrome was diagnosed in
43 (44.8%) patients, and patients without metabolic syndrome were 53 (55.2%)
patients.

CONCLUSIONS: This study conducted in 96 hospitalized patients with chronic heart

failure, which were rehospitalized within 6 months after previous discharge. 44.8%
patients had metabolic syndrome, with dominant risk factors were above normal BMI,
low HDL cholesterol levels, and higl fasting blood sugar levels.

Keywords: chronic heart failure, metabolic syndrome, risk factors