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PHINMA UNIVERSITY OF ILOILO

COLLEGE OF ALLIED HEALTH SCIENCES


Nursing Department

DRUG STUDY
Drug Name Classification/ Indications Contraindications Side effects/ Adverse Nursing responsibilities
Mechanism of Action Effects
Generic Name: Enters target cells and
hydrocortisone binds to cytoplasmic
receptor; initiates many
complex reactions that
are responsible for its
Brand Name:
anti-inflammatory,
Hydrocortone immunosuppressive
cortenema (glucocorticoid),
and salt-retaining
(mineralocorticoid)
Route: actions. Some actions
IVTT may be undesirable,
depending on drug use.

Dosage:100 mg

Frequency:
Q6H

Pharmacologic Class
Adrenal cortical steroid
Corticosteroid
Glucocorticoid
Therapeutic Class
Hormone
Pregnancy category
C

-Replacement therapy
in adrenal cortical
insufficiency
- Allergic states
severe or incapacitating
allergic conditions
- Hematologic disorders
- Ulcerative colitis

Concentrations
- Allergy to any component
of the drug
- Fungal infections
- Amebiasis
- Hepatitis B
- Vaccinia or varicella
- Antibiotic-resistant infections
- Immunosuppression
Precaution
- Kidney disease
- Liver disease
- Cirrhosis
- Hypothyroidism
- Ulcerative colitis with
impending perforation
- Diverticulitis
- Recent GI surgery
- Active or latent peptic ulcer
- Inflammatory bowel disease
- Hypertension
- Heart failure
- Thromboembolic tendencies
- Osteoporosis
- Convulsive disorders
- Metastatic carcinoma
- Diabetes mellitus
- TB
- Lactation

CNS: Vertigo, headache,


paresthesias, insomnia,
seizures, psychosis
CV: Hypotension, shock,
HPN and heart failure
secondary to fluid
retention,
thromboembolism,
thrombophlebitis,
fat embolism, cardiac
arrhythmias
Dermatologic: Thin,
Fragile,skin, petechiae,
ecchymoses, purpura,
striae, subcutaneous
fat atrophy
EENT: Cataracts, glaucoma,
increased IOP
Endocrine: Amenorrhea,
irregular mens,
growth retardation,
decreased carbohydrate
tolerance and DM, cushingoid
state, HPA suppression systemic , hyperglycemia
GI: Peptic or esophageal ulcer,
pancreatitis, abdominal
distention, nausea, vomiting
, increased appetite and weight gain
Hematologic: Na and fluid retention, hypocalcemia, increased blood sugar, increased serum cholesterol, decreased T3 and T4 levels
Hypersensitivity: Anaphylactoid or hypersensitivity reactions
Musculoskeletal: Muscle weakness, steroid myopathy and loss of muscle mass, osteoporosis, spontaneous fractures
Other: Immunosuppression, aggravation or masking of infections, impaired wound healing

Before
- Assess for contraindications.
- Assess body weight,
skin color, V/S,
urinalysis, serum electrolytes,
X-rays, CBC.
- Arrange for increased dosage
when patient is subject to
unusual stress.
- Do not give live vaccines with
immunosuppressive doses
of hydrocortisone.
- Observe the 15 rights of drug
administration.
During
- Give daily before 9am
to mimic normal peak diurnal corticosteroid levels.
- Space multiple doses evenly
throughout the day.
- Use minimal doses for minima
l duration to minimize adverse effects.
- Do not give IM injections if patient has
thrombocytopenic purpura.
- Taper doses when discontinuing
high-dose or long-term therapy.

After
- Monitor client for at least 30 minutes.
- Educate client on the side effects of the medication and what to expect.
- Instruct client to report pain at injection site.
- Instruct client to take drug exactly as prescribed.
- Dispose of used materials properly.
- Document that drug has been given.

PREPARED BY: ___________________________________________