Sialkot College of Physical therapy

DPT, 1st Year, Test 2019

SUBJECT NAME: Physiology
Maximum Marks: 60 Time Allowed: Hours
Section-I MCQs and SEQs

1. Which of the following is not the function of the lungs?

A. Metabolism
B. Serves as a reservoir of blood for left ventricle.
C. It is the filter to protect the systemic vasculature.
D. All of the above are true.

2. Which of the following is the correct path of CO2 from the tissue to the atmosphere?
A. Reaction with H2O to make H2CO3, dissociation to H+ & HCO3-, reserve reaction
forms CO2.
B. O2 is metabolized to CO2. Reaction with H2O to make H2CO3. H2CO3 combines
with imidazole side chain of hemoglobin, H2CO3HB+ is carried back to lungs, reverse
reaction from CO2.
C. Reaction with H2O to make H2CO3, dissociation to H+ & HCO3-, HCO3- combines
with imidazole side chain of hemoglobin. Carried back to the lungs as HCO3-HB+ &
H+, reverse reaction from CO2.
D. O2 is metabolized to CO2, reaction with H20 to make H2CO3, dissociation to H+&
HCO3-, carried back to lungs in this form, reverse reaction forms CO2.
3. Which of the following is NOT an effector of respiration?

A. Heart
B. Diaphragm
C. Intercostals
D. Trapezius

4. Which of the following is the first branching of the bronchial tree that has gas exchanging
capabilities?

A. Terminal bronchioles.
B. Respiratory bronchioles.
C. Alveoli
D. Segmental bronchi

5. Which of the following could NOT be part of an acinus?

A. Alveolar sacs
B. Alveolar ducts
C. Terminal bronchioles
 D. Respiratory bronchiole.
6. Regarding binding of oxygen with hemoglobin (Hb):
A. Oxygen loosely combines with two positive bonds of iron in Hb molecule.
B. Oxygen firmly binds with 1 of the coordination bonds of iron atom.
C. Oxygen is carried to the tissues in molecular form by hemoglobin.
D. Oxygen is released by Hb into the tissues in ionic form.

7. The 1st step of Heme synthesis takes place in the:

A. Mitochondria
B. Golgi apparatus
C. Rough endoplasmic reticulum
D. Peroxisomes

8. Regarding the blood coagulation test “Prothrombin time”

A. It is normally about 12 minutes.
B. It indicates concentration of thrombin in blood.
C. It involves intrinsic clotting pathway.
D. It shortens with rise in Prothrombin concentration.
9. A 24 year old African American man comes to the emergency room 3 hours after the
onset of severe back & chest pain which started when he was climbing up a mountain.
He had an episode of same symptoms five years ago. His values are Hb: 11gldl, TLC:
12000/mm3, reticulocyte count: 25% what is the diagnosis of this patient?
A. Acute blood loss.
B. Sickle cell anemia.
C. Anemia of chronic disease
D. End stage kidney disease
10. Which of the following treatments would prevent a transfusion reaction?
A. Administration of plasma free blood.
B. Administration of washed erythrocytes
C. Treatment with immunoglobulins.
D. Proper cross-matching of donor red cells with recipient plasma.

11. Wall of Larynx is supported by the cartilage.

A. Cricoid
B. Thyroid
C. Artynoid
D. All these

12. Residual volume of the lung is

A. 1200 ml
B. 1500 ml
C. 4500 ml
D. 500 ml
13. Partial pressure of O2 in the inspired air is 156 mm Hg & that of CO2 is
A. 0.3 mm Hg
B. 0.5 mm Hg
 C. 140 mm Hg
D. 46 mm Hg

14. Expiratory muscles contract at the time of

A. Deep inspiration
B. Normal inspiration & Expiration
C. Forceful expiration
D. Normal expiration

15. Inflammation of the lung covering severe chest pain is

A. Emphysema
B. Pleurisy
C. Asphyxia
D. Hypoxia

Q.2. Write answers of the following up to 25 lines maximum.

1: What is physiology of respiratory system?
2: What is the main role of oxygen in cellular respiration?
3: How does lung volume change initiate respiration?
4 (a) what is pleural effusion, name its two causes?
(b) Discuss factors that affect the rate of gas diffusion through respiratory membrane.

5: Explain in detail chemical control of respiration.

6: Define Residual volume.

Section-II Leqs-
1: Describe various zones of pulmonary blood flow? How carbon dioxide is transported in the
body?
2: Describe effect of diminished alveolar oxygen on local alveolar blood flow and its
importance?