Name: PRAKTIKUM FISIOLOGI 6

Exercise 2: Skeletal Muscle Physiology: Activity 6: The Skeletal Muscle Length-Tension Relationship Lab Report

Pre-lab Quiz Results

You scored 20% by answering 1 out of 5 questions correctly.

1. During an isometric contraction

Your answer : c. there is no active contraction within the skeletal muscle.
Correct answer: d. the skeletal muscle is generating force, but it remains at a fixed length.

2. The force that results from muscles being stretched is

Your answer : c. total force.
Correct answer: a. passive force.

3. Active force
You correctly answered: b. is determined by the amount of myosin bound to actin.

4. When you generate the isometric length-tension curve, which of the following forces will not be indicated on your
screen?
Your answer : b. active force
Correct answer: c. tetanic force

5. Passive force in skeletal muscle is largely caused by

Your answer : a. the actin thin filaments.
Correct answer: c. the protein titin.

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Experiment Results
Predict Question:
Predict Question: As the resting length of the muscle is changed, what will happen to the amount of total force the muscle
generates during the stimulated twitch?
Your answer : d. An increase in muscle length will decrease the total force.

Stop & Think Questions:

Note the dip in total force at a muscle length of
90 mm as compared to the total force at a muscle length of 80 and 100 mm. Why does this occur?
You did not answer this question.
Correct answer: d. At this muscle length, active force has decreased in value and passive force has not yet increased to a
significant value.

Experiment Data:

Voltage Length Active Force Passive Force Total Force

8.5 75 1.82 0.0 1.82
8.5 70 1.75 0.0 1.75
8.5 65 1.55 0.0 1.55
8.5 60 1.21 0.0 1.21
8.5 55 0.73 0.0 0.73
8.5 50 0.11 0.0 0.11
8.5 80 1.75 0.02 1.77
8.5 90 1.21 0.25 1.46
8.5 100 0.11 1.75 1.86

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Post-lab Quiz Results
You scored 20% by answering 1 out of 5 questions correctly.

1. When a skeletal muscle is stimulated and generates force but remains at a fixed length
Your answer: c. there is no active force developed within the muscle.
Correct answer: d. the muscle is contracting isometrically.

2. Which protein is mostly responsible for the development of passive force in a muscle?
Your answer: b. myosin
Correct answer: d. titin

3. In skeletal muscle, active force stimulated through a range of muscle lengths

You correctly answered: b. will utilize ATP hydrolysis to drive the cross bridge cycle.

4. Which of the following is not depicted in a typical skeletal muscle isometric length-tension curve?
Your answer: c. total force
Correct answer: a. time

5. Maximal active tension will be produced in a skeletal muscle fiber when

Your answer: d. the fiber is at any length because tension is not dependent on muscle length.
Correct answer: a. the fiber is at its resting length.

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Review Sheet Results
1. What happens to the amount of total force the muscle generates during the stimulated twitch? How well did the results
compare with your prediction?
You did not answer this question.

2. What is the key variable in an isometric contraction of a skeletal muscle?

You did not answer this question.

3. Based on the unique arrangement of myosin and actin in skeletal muscle sarcomeres, explain why active force varies
with changes in the muscle's resting length.
You did not answer this question.

4. What skeletal muscle lengths generated passive force? (Provide a range.)

You did not answer this question.

5. If you were curling a 7-kg dumbbell, when would your bicep muscles be contracting isometrically?
You did not answer this question.

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