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UROLOGICAL SYSTEM
6
Figure 40-1
The Renal System
Kidneys and Ureters
• Kidneys are bean-shaped organs located just
under and below the 12th rib near the waist
in the body trunk
• The entire blood supply circulates through
the kidneys every 4 to 5 minutes.
Figure 40-2
The kidneys are essentially regulatory organs
which maintain the volume and composition of
body fluid by filtration of the blood and
selective reabsorption or secretion of filtered
solutes.
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Figure 40-3
An illustration of the internal structures of the kidney.
18
Nephron
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tml
Figure 40-4
Structure of the Nephron
The nephron is the unit of the kidney responsible for ultrafiltration of the
blood and reabsorption or excretion of products in the subsequent filtrate.
Each nephron is made up of:
A filtering unit- the glomerulus. 125ml/min of filtrate is formed by the
kidneys as blood is filtered through this sieve-like structure. This filtration is
uncontrolled.
The proximal convoluted tubule. Controlled absorption of glucose, sodium, and
other solutes goes on in this region.
The loop of Henle. This region is responsible for concentration and dilution of urine
by utilising a counter-current multiplying mechanism- basically, it is water-
impermeable but can pump sodium out, which in turn affects the osmolarity of the
surrounding tissues and will affect the subsequent movement of water in or out of
the water-permeable collecting duct.
The distal convoluted tubule. This region is responsible, along with
the collecting duct that it joins, for absorbing water back into the
body- simple maths will tell you that the kidney doesn't produce
125ml of urine every minute. 99% of the water is normally
reabsorbed, leaving highly concentrated urine to flow into the
collecting duct and then into the renal pelvis.
Bladder and Urethra
• Bladder: muscular sac; stretches to store urine
• On floor of pelvic cavity behind the peritoneum
• In front of the rectum in men; in front of the vagina and
uterus in women
• Trigone: triangular-shaped area on posterior wall
• Control possible by sensory and motor nerves
• Urethra: muscular tube lined with mucous membranes;
carries urine from bladder out of the body
Figure 40-5
Urine (the filtered product containing waste materials
and water) excreted from the kidneys passes down the
fibromuscular ureters and collects in the bladder. The
bladder muscle (the detrusor muscle) is capable of
distending to accept urine without increasing the
pressure inside; this means that large volumes can be
collected (700-1000ml) without high-pressure damage
to the renal system occurring.
When urine is passed, the urethral sphincter at the base
of the bladder relaxes, the detrusor contracts, and urine
is voided via the urethra.
Functions of the Kidney
• Regulation of water excretion
• Regulation of electrolyte function
• Regulation of acid-base balance—retain
HCO3- and excrete acid in urine
• Regulation of blood pressure--RAAS
• Regulation of RBCs
• Vitamin D synthesis
Functions of Kidney cont.
• Secretion of prostaglandin E and prostacyclin
which cause vasodilation, important in
maintaining renal blood flow
• Excretion of waste products-body’s main
excretory organ. Urea, creatinine, phosphates,
uric acid and sulfates. Drug metabolites.
Physiology of the Urinary System
• Regulation and excretion
– Urine production
• Glomerular filtration, tubular reabsorption, and
tubular secretion
– Urine elimination
– Regulation of serum calcium and phosphate
– Regulation of blood pressure
– Hormonal stimulation of red blood cell
production
Urine Formation Processes
Filtration
Reabsorption
Secretion
Figure 15.4
Figure 15.5
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Slide
Figure 40-6
Physiology/Pathophysiology
Renin-angiotensin system
Stimuli for Renin Excretion
Angiotensinogen in liver
Renin release
Angiotensin I
Angiotensin II
Renal autoregulation
• Can be severe
– urinary tract obstruction
– inflammation
• Inflammation of the GU tract is most severe when it involves
the parenchyma of a GU organ
– Pyelonephritis
– Prostatitis
– Epididymitis
• Inflammation of the mucosa of a hollow viscus usually
produces discomfort
– Cystitis
– Urethritis
Pain
• Tumors:
– No pain unless
• obstruction
• extend beyond the primary organ to involve adjacent
nerves
Pain
• Renal Pain
– Site: ipsilateral
costovertebral angle just
lateral to the
sacrospinalis muscle and
beneath the 12th rib
– Overdistention
– inflammation
Prostatic Pain
• Inflammation with secondary edema and distention
of the prostatic capsule
• poorly localized
– lower abdominal
– Inguinal
– Perineal
– Lumbosacral
– rectal pain.
– irritative urinary symptoms ( frequency and dysuria)
– acute urinary retention.
Penile Pain
• Pain in the erect penis is usually due to
Peyronie's disease or priapism
• Pain in the flaccid penis
– usually secondary to inflammation in the bladder
or urethra
– referred pain that is maximally at the urethral
meatus
• paraphimosis
Testicular Pain
• Acute pain
– epididymitis
– torsion of the testicle
• Chronic scrotal pain
– hydrocele
– varicocele,
– dull, heavy sensation that does not radiate
– Referred pain: kidneys or retroperitoneum
Hematuria
• Hematuria : the presence of blood in the urine
KIDNEY Costovertebral angle, may Dull constant ache; if n/v, diaphoresis, pallor, Acute obstruction, kidney
extend to umbilicus sudden distention of signs of shock stone, blood clot, acute
capsule, pain is severe, pyelonepritis, trauma
sharp, stabbing and colicky
in nature
BLADDER Suprapubic area Dull, continous pain, may Urgency, pain at the end of Overdistended bladder,
be intense with voiding, voiding, painful straining infection, interstitial
may be severe if bladder is cystitis; tumor
full
URETERAL Costovertebral angle, Severe, sharp, stabbing n/v, paralytic ileus Ureteral stone, edema or
flank, lower abdominal pain, colicky in nature stricture, blood clot
area, testis or labium
PROSTATIC Perineum and rectum Vague discomfort, feeling Suprapubic tenderness, Prostatic cancer, acute or
of fullness in perineum, obstruction to urine flow, chronic prsotatitis
vague back pain frequency, urgency,
dysuria, nocturia
URETHRAL Male: along penis to Pain variable, most severe Frequency, urgency, Irritation of bladder neck,
meatus; female: urethra to during and immediately dysuria, nocturia, urethral infection of urethra,
meatus after voiding discharge trauma, foreign body in
lower urinary tract
Entry Points to Physical Examination
• Properly taken medical history
• Aim at performing a thorough and complete
physical examination
• Aim- to evaluate patients who present with
medical problems
• Why?
• Physical examination (P/E) remains to be the key
component of diagnostic evaluation along with
properly taken history
• What is expected?
• To perform conscientiously – “Take time”
Diagnostic Evaluation
Diagnostic evaluation will point to the nature
of the disease:
• Congenital
• Infections and infestations
• Metabolic problems
• Traumatic
• Neoplastic
Diagnostic Evaluation Cont’d
• Diagnostic evaluation begins as the patient
comes in or the physician/medical trainee
comes in to evaluate the patient
• General assessment of severity of the
illness/medical condition – “visual inspection”
• Evidence of pain
• Nutritional status: weight loss/obesity
• Gait
• Abnormal body movements
• Wetting
• Fever
• Edema
Diagnostic Evaluation Cont’d
• Pick features that draws attention to disorders
in another system and examine that system:
• Edema – cardiac disease, renal failure etc.
• Gynacomastia – alcoholism, endocrinologic diseases,
post chemotherapy (for example, for prostatic cancer)
• Lymphadenopathy – metastatic genitourinary (GU)
neoplasms
Diagnostic Evaluation Cont’d
• During examination of the GU tract look for:
• Enlargement of the kidneys
• Enlargement of the bladder
• Disorders of the inguinal region
• Disorders of the genitalia
• Pelvic disease detectable by internal examination
(Digital Rectal Examination-DRE and per vaginal
examination - PV)
• Neurological examination
Physical Examination
• Skin color (ashen, yellow); crystals on skin (uremic frost)
• Tissue turgor: to detect dehydration or edema
• Periorbital edema: suggests fluid retention. Inspect the mouth for
moisture and odor
• Observe respiratory rate, pattern, and effort
• Auscultate the lungs for crackles or rhonchi
• Inspect the abdomen for scars and contours, and palpate for tenderness
and bladder distention
• Auscultate the kidney area over costovertebral angle (Figure 40-2) to
detect renal bruits
• Edema
• Inspect the genitalia
Figure 40-2
PHYSICAL EXAMINATION
• General Observations
– visual inspection of the patient
– Cachexia
• Malignancy, TB
– Jaundice or pallor
– Gynecomastia
• endocrinologic disease
• alcoholism
• hormonal therapy for prostate cancer
Physical Assessment of Urinary System
• Inspection
• Inspection including examination of abdomen and urethral
meatus
• Auscultation including renal arteries
• Percussion includes the kidneys to detect tenderness
• Palpation to detect any mass, lumps, tenderness
Percussion of the kidney
• To detect areas of tenderness by costovertebral test, normally
will feel a thudding sensation or pressure but not tenderness
Palpation of kidney
• Contour, size, tenderness, and lump.
• In adult normal the kidneys not be palpable because of their
location deep with abnormal.
• Elderly the right kidney is slightly lower than the left, it may be
easier to palpate.
88
Percussion of the bladder
• Percuss the area over the bladder (5cm) above the symphysis pubis.
• To detect difference in sound, percuss toward the base of the bladder.
• Percussion normally produces a tympanic sound.
Palpation of bladder
• Normally feel firm and smooth.
• In adult bladder may not be palpable
Inspection of the urethral meatus
• Look for swelling, discharge and inflammation
Assessment of Urine
• Urine assessment includes:
• Measure volume of urine
• Inspect color, clarity, and volume
• Test the specific gravity, glucose, ketone bodies and blood and pH
• Normal urine volume 1-2 litter per 24 hours (normal adult)
89
• Color: typically yellow-straw but varies according to recent diet
and concentration of the urine. Drinking more water generally
tends to reduce the concentration of the urine and therefore
cause it to have a lighter color. (The converse is also true.)
• Smell: Generally fresh urine has a mild smell but aged urine has
a stronger odor, similar to that of ammonia.
• The smell urine may provide health information. For example,
urine of diabetics may have a sweet or fruity odor due to the
presence of ketones.
• Acidity: PH is a measure of the acidity (or alkalinity of a
solution). PH is a measure of the activity of hydrogen ions (H+)
in a solution.
• 95% Water, 5% chemical solutes. Urea from breakdown of
amino acids (protein) to give ammonia + C02 giving urea and
creatinine from breakdown of creatine phosphate in muscle
90
Collection of urine samples
• All urine tests are ideally performed on fresh specimens:
• Urine container has been adequate protection agonist bacterial
contamination and chemical deterioration
• Identification or labeled should be provided.
• The patient should then be gowned for the physical examination
• Bring it into the dry room
• Urine specimens should collect from the patient means of the clean–
catch midstream technique.
• All specimens should be refrigerated as soon as possible they are
obtained to avoid shifting of the PH of urine to alkaline because
contamination of urea- splitting bacteria from the environment.
Consider the Developmental Stages
• Pediatric: difficulties, crying, change in urinary in childhood.
• Pregnant: Pain during urination, normal increase urine in volume and
frequency and decrease urine specific gravity.
• Elderly: how much and how type of liquid do you drink in the evening?
do you ever lose of control of your bladder?
91
DETAILED PHYSICAL EXAMINATION
• Read and practice in the skills Lab
Examination
Pallor, Jaundice
Loss of weigh, over weight
Cervical Lymph nodes
Kidneys
• Palpation of the kidneys
– supine position
– The kidney is lifted from behind with one hand in
the costovertebral angle
– In neonates, palpating of the flank between the
thumb anteriorly and the fingers over the
costovertebral angle posteriorly
Abdominal Examination
Kidneys
• Auscultation : epigastrium for bruit
– renal artery stenosis
– aneurysm.
– renal arteriovenous fistula.
Abnormal Physical Examination Findings—
Kidneys
• The most common abnormality detected on
examination of the kidneys is a mass
• In neonates and younger children, the
transillumination helps to distinction between
cystic and solid
Abdominal Examination of the GU Tract
107
Physical Signs of an Enlarged Bladder
Cont’d:
Physical Signs of an Enlarged Bladder
Cont’d:
• Floppy bladder
• Cystic mass
• May be more to one side
• Bladder moves from side to side only
• Gravid uterus moves from side to side and up
and down
• Bimanual Examination (BME)
• Suprapubic fluid filled bladder
• Irregular mass
• Cystic mass
• BME under anesthesia (for better assessment
of a bladder mass)
• Bladder palpated between the abdomen and the rectum in males
and between the abdomen and the vagina in females
Physical Signs of an Enlarged Bladder
Cont’d
• Abnormal findings are:
• Over distended bladder noticeable and palpable
– Bladder outlet obstruction (BOO)
– Neurogenic conditions
• Large bladder tumors or calculi
• Tenderness - cystitis
Penis
• The position of the urethral meatus
• Priapism: sickle cell disease
Hypospadias
Scrotal masses
Inspection Palpation
• Site • Temp.
• Size • Tenderness
• Shape
• Consistency
• Skin
• Others according
• Cough impulse
to diagnosis
Scrotum and Contents
• Painful
– Torsion
– Epididymitis firm or hard area within the testis should be considered a
malignant tumor until proved otherwise
• Painless
– Spermatocele
– Hydrocele
– Varicocele
Risk for impaired skin integrity r/t urinary Total urinary incontinence
incontinence
Situational low self esteem r/t
incontinence
INCONTINENCE
• Functional = d/t inability to get to toilet as in
altered mobility, or altered cognition
• Overflow = loss of urine d/t over distention of
bladder (urinary retention)
• Stress = leakage with increased intra-
abdominal pressure
• Reflex = d/t neuro deficits ie spinal cord injury
• Urge = leakage accompanied by sudden
urgency
• Total = continuous loss of urine d/t ex fistula
Outcome Criteria
Patient will:
• Empty bladder completely at regular
intervals
• Decrease episodes of incontinence
• Maintain regular urinary elimination
pattern
• Develop adequate Intake/Output
• Have decreased dysuria
Nursing Interventions
• Maintain voiding habits
• Promote fluid intake
• Strengthen muscle tone
Kegels 30-80/day
• Stimulate urination
Auditory
Tactile
Implementation…..
• Maintain habits by promoting, scheduling,
positioning, hygiene.
• Privacy & Comfort
• Allow adequate time to void
• Promote relaxation - breathing, imagery etc.
• Fluid intake 2000cc/day
• Kegel exercises to strengthen pelvic muscles30-80
times/day for 6 wks
Implementation Cont….
• Stimulate urination…privacy, position,running water,
warm water over perineum Auditory- sound of
running water
• Tactile- feel of water, place hands in warm water,
pour warm water over perineum
• Application heat/cold, apply warm soaks over pubic
area may decrease muscle tension. Sitz bath
• Apply cold packs over abd. may increase muscle
contraction…
• Avoid increasing Anxiety by over emphasizing the
problem
Interventions: Toileting
• Toilet
• Commode • Safety Concerns
• Bedpan
• Urinal • Female Hygiene
• Disposable“ Hat”
• Fx pan
Interventions for Urinary
Incontinence
• Bladder training/ Habit training
• Bladder training- postpone voiding according
to timetable rather than urge…gradually
lengthen intervals stabilize bladder decrease
urgency
• Habit training- timed voiding to keep dry…no
motivation to delay voiding if urge occurs
• External urinary device
- Condom Catheter
• Indwelling catheter-LAST resort
Condom Catheter (Texas Cath)
• Rubber condom placed on penis of
incontinent males
• Connects to drainage bag to collect
urine
• Easy to apply and observe
• Comfortable
• Doesn’t require intubation
• Prevents skin irritation from
incontinence
Condom Catheter
• Check every 2-4 hrs.
• Remove and replace every 24 hrs.
• Maintain free urinary drainage
• Never tape to skin
• Leave 1-2 inch space at tip of penis
• Secure snuggly but not too tight
• Follow manufacturer instructions
Urinary Catheterization
Used to:
• Keep bladder deflated during surgery
• Measure residual urine
PVR (post void residual) should be < 50 ml
• Relieve retention
• Obtain sterile urine specimen
May use either:
• Straight catheter or indwelling catheter
Indwelling catheter
• Catheter inserted into urinary meatus through urethra
into bladder to drain urine
• Last resort as it introduces microbes into bladder…leading
to UTI (urinary tract infection)
• Performed using sterile technique...MD order needed
• Remains in place via inflated balloon
ALSO
Suprapubic Catheter – diverts urethra
Urologic Stents- temporary in ureters
permanent in urethra
Ileal Conduit – diversion of ureters to
ileum and stoma; requires appliance
Medications Affecting Urinary
Elimination
• Routine urinalysis
• Clean-catch/midstream urine
• Sterile specimen ( catheterization or
from indwelling catheter)
• 24 hr. urine
Evaluating Urinary Elimination
• Frequency
• Amount
• Ease/Difficulty
• Color
• Appearance
• Odor
Diseases & Disorders
Congenital
Congenital hydronephrosis
Congenital obstruction of urinary tract
Duplicated ureter
Horseshoe kidney
Polycystic kidney disease
Renal dysplasia
Unilateral small kidney
Multicystic dysplastic kidney
Big Kidney
Acquired
Diabetic nephropathy
Glomerulonephritis
Hydronephrosis is the enlargement of one or both
of the kidneys caused by obstruction of the flow of
urine.
Interstitial nephritis
Kidney stones are a relatively common and
particularly painful disorder.
Kidney tumors – Wilms tumor, Renal cell
carcinoma
Acquired cont..
Lupus nephritis
Minimal change disease
In nephrotic syndrome, the glomerulus has been
damaged so that a large amount of protein in the
blood enters the urine. Other frequent features of
the nephrotic syndrome include swelling, low serum
albumin, and high cholesterol.
Pyelonephritis is infection of the kidneys and is
frequently caused by complication of a urinary tract
infection.
Renal failure – Acute renal failure, Stage 5 Chronic
Kidney Disease
COMMON DISEASES IN RENAL
Acute renal failure, a sudden loss of renal
function
Chronic kidney disease, declining renal
function, usually with an inexorable rise in
creatinine.
Hematuria, blood loss in the urine
Proteinuria, the loss of protein especially
albumin in the urine
Microalbuminuria, slight increase in urinary
albumin excretion
Cont…..
Electrolyte disorders or acid/base imbalance
Kidney stones, usually only recurrent stone
formers.
Nephrosis, degeneration of renal tubular
epithelium.
Nephritis, inflammation of the kidneys
Chronic or recurrent urinary tract infections
Hypertension that has failed to respond to
multiple forms of anti-hypertensive medication
or could have a secondary cause
• Thank you
• Questions……