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J Am Dent Assoc, Vol 132, No 7, 883-889.

© 2001 The American Dental Association
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P.P. HUJOEL, Ph.D., M. DRANGSHOLT, D.D.S., M.P.H.,
C. SPIEKERMAN, Ph.D. and T.A. DEROUEN, Ph.D. Google Scholar

Articles by HUJOEL, P.P.

Background. While it has been suggested that periodontal disease Articles by DEROUEN, T.A.
may be associated with coronary heart disease, or CHD, there are no Articles citing this Article
data to suggest that the elimination of chronic dental infections
PubMed
actually lowers the risk of developing chronic CHD. The goal of this
study was to determine whether people with a definitive elimination of PubMed Citation
all potential dental infections—edentulous people, who are at the Articles by HUJOEL, P.P.

optimum endpoint of dental infection elimination from a CHD Articles by DEROUEN, T.A.
perspective—lower their CHD risk over time when compared with
people who have a specific dental infection, periodontitis.

Methods. The authors examined data from a prospective cohort of 4,027 people who participated in the
First National Health and Nutrition Examination Survey, or NHANES I, Epidemiologic Follow-up Study. The
primary outcome measure was the first CHD event.

Results. During a mean follow-up of 17 years, there were 1,238 CHD events (538 fatal). The confirmed
elimination of chronic dental infections did not lead to a decreased risk of experiencing a CHD event
(relative risk, 1.02; 95 percent confidence interval, 0.86–1.21). The CHD risk among people with and
without chronic dental infections remained constant over time with respect to each other (test for increasing
or decreasing trend over time: not significant, 21 = 0.48; P = .93).

Conclusions. People who had a complete, definitive and long-term elimination of all potential dental
infections through extraction of all teeth did not have lower CHD risk when compared with people with
diagnosed periodontitis.

Clinical Implications. Until evidence is found to the contrary, the authors suggest that prevention of CHD
should not be used as the basis for recommending treatment to eliminate chronic dental infections.

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Examining the link between coronary heart disease and the eliminati... http://jada.highwire.org/cgi/content/abstract/132/7/883

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Examining the link between coronary heart disease and the eliminati... http://jada.highwire.org/cgi/content/abstract/132/7/883

[Abstract] [Full Text] [PDF]

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Copyright©1995-2001 American Dental Association (ADA).
Reproduction or republication strictly prohibited without prior written permission of ADA.

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