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By Researchers: STEM-Ecclesiastes
Daisyree Eco
Samantha De Guzman
KenethDela Cruz
Aisha Chandra
Earl Adal
Ashary Dao
Chapter 1
Introduction
First and foremost, why did we come up to this study? As we can see in the present
time, people have discovered many. Various inventions and more, and at the same time is the
development of diseases. Many diseases are being discovered and would be discovered, so the
only thing we can do is to get things ready. Vaccination or immunization programs will help us
to prepare ourselves through being vaccinated in order for us to prevent variety of diseases that
Why should someone get immunized? The goal of public health is to prevent disease. It's
much easier and more cost-effective to prevent a disease than to treat it. That's exactly what
Immunizations or vaccinations protect us from serious diseases and also prevent the
spread of those diseases to others. Over the years immunizations have prevent epidemics of once
common infectious diseases such as measles, mumps, and whooping cough. It is often stated
that vaccination has made the greatest contribution to global health of any human intervention.
But despite of all the advantages of vaccine, it’s effectiveness has been questioned due to the
Immunization is one of the most cost-effective solutions to major global challenges and
vaccination prevents an estimated 2.5 million deaths annually. With the exception of clean water,
no other modality prevents more deaths than vaccination. 1 The Philippines is now the 44th
country to be certified as having eliminated maternal and neonatal tetanus. 2 This was achieved
primarily by ensuring hygienic delivery and cord care practices, and by immunizing children and
women. On 29 November 2017, a press statement was released by Sanofi Pasteur regarding the
results of the new analysis of clinical trial data of the dengue vaccine, CYD-TDV (Dengvaxia®).
Based on this information, persistent protection against dengue fever was provided by the
vaccine among those who had prior infection. However, for those not previously infected by the
dengue virus, more cases of severe disease may occur upon a subsequent dengue infection
following vaccination. 3 Since this announcement, the Department of Health (DOH) placed the
dengue vaccination program on hold until further review. Concerns about the safety of dengue
vaccine in the public health program are the trending topics in the news and in social media. In
the ongoing discussions with the dengue vaccine, the value of routine childhood vaccination is
being drowned by fear and panic. There is a possible risk that all the media attention to one
vaccine will lead to distrust of all other vaccines in the national immunization program and result
in lower vaccine coverage, affecting not just school age vaccination, but even infant
immunization. Reductions in vaccine coverage may lead to disease outbreaks such as the 2013
measles outbreak in the country. 4 In 2013, Vietnam suspended the use of pentavalent
deaths that occurred after pentavalent immunization. The suspension of the pentavalent vaccine
in Vietnam is estimated to result in 90,137 chronic infections and 17,456 future deaths due to
hepatitis B in the 2013 birth cohort. 5 The deaths which lead to the suspension were eventually
assessed as not due to the pentavalent vaccine. In the past five years, the Philippines has
introduced several new vaccines in the expanded immunization program of the government,
namely, mumps, rubella, inactivated poliovirus, and pneumococcal conjugate vaccines. The
are substantial breakthroughs in ensuring prevention of disease for all Filipino children. Vaccines
have never been free from risk, hence, decisions on new vaccine introduction require risk-benefit
analysis. A survey on vaccine safety and confidence showed that 92.7% and 80% of surveyed
Filipinos strongly agreed that vaccines are important and safe, respectively. 7 The trust and
confidence of the Filipinos in the immunization program should not be eroded by this experience
to one vaccine. Health professionals and societies must strive to support all efforts to ensure that
the country does not fail its citizenry in providing the best health care services.
1.2 Theoretical Framework
Commitment to risk culture / healthism (horizontal axis) and distrust/trust toward health
Thus we propose to add to the risk culture/healthism axis a second axis, assessing lay people’s
respondents in vaccination/immunization
Research
terms of: programs for children with
Content Analysis
1.1 Gender age 6 months to 16 years old
Survey
1.2 Age in Brgy. Tanyag, Taguig
Statistical
1.3 Life Estate City despite of the
analysis of data
2. Views on dengvaxia controversy in
programs. implements
vaccination/immunization
program.
1.4 Statement of the Problem
The study aimed to seek answers regarding public trust and acceptance on implementing
vaccination programs for children aged 6 months to 16 years old at Brgy. Tanyag Taguig City,
1.1 Gender
1.2 Age
3. What are the foreseen problems of the residents regarding vaccination programs.
1.5 Hypothesis
1. There is no significant difference between the views of the residents on the implementation of
free vaccination programs for children with age 6 months to 16 years old in terms of preventing
2. There is no significant difference between the foreseen problems of the residents regarding
implementation of free vaccination programs for children with age 6 months to 16 years old.
1.6 Significance of the Problem
This study determined the perception of the residents of Brgy. Tanyag, Taguig City
towards implementing free vaccination programs for children with age 6 months to 16 years old
The researcher provided a rational and precise information, study and evaluation of the
policy and advocacy, as an additional definite knowledge required while making this research to
know the different perception of the residents of Brgy. Tanyag, Taguig City towards
implementing free vaccination programs for children with age 6 months to 16 years old.
Barangay Administration. This research is beneficial for the barangay administration because
they would increase their awareness and they will be more careful in conducting and receiving
Parents. This may be useful to because they will regain again their trust to use the vaccine for
their children.
Children. Mainly, this research is useful especially for their health and awareness because they
Future Researchers. This research is advantageous to future researchers as this will serve as
one of their resources. This may also help them to be a guide of the research that they will
conduct. This study will also serve as basis for further research about implementing free
vaccination programs for children with age 6 months to 16 years old Brgy. Tanyag, Taguig City.
Researchers. The researchers will enhance their ability to understand a concept. This also helps
them to elevate their mental abilities in terms of gathering data and information. Additionally, to
This study focused on the perception of the residents towards implementing free
vaccination programs for children with age 6 months to 16 years old at Brgy. Tanyag, Taguig
City, and this is an assessment on public trust and acceptance on vaccination programs due to
Definition of Term/Acronyms
To gain more understanding, the following keywords, terms, phrases, and acronyms used
in the conceptual framework of this research were hereby operationally defined, to wit:
tetravalent dengue vaccine, based on the yellow fever 17D vaccine strain, given as a 3-dose
series with 6 months between each dose. The vaccine has 4 components, encoding for antigens
of the four dengue virus strains. Dengvaxia is the first dengue vaccine to be licensed.
researches and studies and will be reviewed in order to understand how they tackled their
respective perception about implementing free vaccination for children despite of dengvaxia
controversy. Likewise, the researchers would like to know the theories they used and the
Aika Rey (2018) the vaccine can prevent 11,000 hospitalization and 2,500 severe dengue
cases if given to 1 million children over age 9. But it can also lead to 1,000 hospitalizations and
Castillo (2017) doctors have added one more vaccine to their list of recommended
immunization shots for children ages 0 to 18 years old, for a total of 14 vaccinations in all for
Filipino children. The Dengue Tetravalent vaccine, which was made available in the Philippines
early last year, is now on the recently released Childhood Immunization Schedule for 2017. The
guide is prepared annually by the Philippine Pediatric Society (PPS) along with the Pediatric
Infectious Disease Society of the Philippines and the Philippine Foundation for
Vaccination (PFV).
Doctors from the above groups recommend the dengue vaccine be administered to children 9
years old and above. Three injections (or "doses") are needed to complete the vaccination.
Megacities (2015) the degree of risk to an individual traveler can vary considerably
based on which part of the country one is going to, the duration of that visit, the accommodation,
the time of year, and the kinds of activities one will be participating in. It is important to note
that those who are planning to travel to the Philippines need to consult with a travel medicine
physician to assess the risks of tropical diseases in the country and to get vaccines for these
diseases. However, if you are already in the Philippines and would like to get vaccinations for
certain diseases, you can contact the Philippine General Hospital (PGH) or take a look at our list
Valido (2018) conducted a research that aims to illustrate the acceptability of the
dengue vaccine before and after the dengue vaccination suspension in urban poor communities in
There were 12 interviews conducted in November 2017 and 5 focus group discussions in
January 2018, a month after vaccine program suspension with 41 participants. All participants
were selected through purposive criterion sampling. Thematic analysis showed acceptability of
the dengue vaccine was associated with parental experience with vaccination and dengue, trust in
suspension triangulation indicated that the parents regretted the experience, trust to public
institutions was eroded and the communication strategy was deemed inadequate. This led to low
Asia’s first dengue vaccination programme has been launched and is picking up steam in
The Philippines became the first Asian country to license Sanofi Pasteur’s dengue
December 11.
recommended for individuals aged 9 to 45. The challenge with dengue is to develop a vaccine
that is safe and effective against all four dengue strains. Dengvaxia is assessed to be 90 per cent
effective.
President Benigno Aquino III was also present when DOH secretary Janette Garin administered
Only 32% of Filipinos have confidence in vaccines following the recent Dengvaxia
controversy—a dramatic drop in confidence rates that may spell disaster when it comes to
Thanks to the Vaccine Confidence Project, we see that confidence levels in 2015 showed 93%
“strongly agreeing” that vaccines are important in 2015. In 2018, after the public outrage around
30), the United Nations Children's Fund (UNICEF) in the Philippines has released a statement to
draw attention to the importance and shared responsibility for vaccination, to ensure all Filipino
DENGVAXIA SCARE
Health Undersecretary Enrique Domingo says only 50% to 60% of children are getting
ILOCOS SUR, Philippines – Almost a year after the Dengvaxia controversy caused a
media frenzy, the Department of Health (DOH) said people are still scared of government's free
September 26, parents are still unwilling to have their children immunized in their various
vaccination programs.
PHILIPPINES: KIDS VACCINATION RATE DOWN TO 60% AFTER DENGVAXIA
SCARE – DOH
MANILA, Philippines – The Department of Health (DOH) is alarmed as more and more
parents are refusing to avail of the government’s various vaccination programs following the
Dengvaxia mess.
Health Undersecretary Enrique Domingo said on Friday, February 2, that only about
60% of Filipino children are getting their scheduled vaccines, when the DOH’s annual
The health official made the statement on the same day that the DOH and the experts
panel from the University of the Philippines-Philippine General Hospital bared the results of the
analysis of 14 cases of children who died after getting vaccinated with Sanofi Pasteur’s
Three vaccinated children developed and died of dengue, 9 died due to various diseases
they got after their vaccination, while the cause of death of the last two cases remain unknown.
Sanofi announced Dengvaxia may lead a person to develop severe dengue if he or she had not
The parents are now refusing to avail of free government vaccines that could prevent
their kids from getting other preventable diseases like polio and measles.
2.4 Foreign Studies
the Recommended Immunization Schedules for Children, Teens and Adults. The CDC’s
Pediatrics and the American Academy of Family Physicians, is the only vaccination schedule
The vaccines recommended in the schedule are carefully timed to provide protection to
children when they are most vulnerable to diseases, and when the vaccines will produce the
strongest response from the child’s immune system. It is therefore very important to follow the
According to Vanderslott and Roser (2015) vaccines have greatly reduced the
prevalence of diseases and they continue to be important for global health today. This entry
explains how vaccines work, which vaccines are available and who in the world is protected by
them. We also discuss the consequences of the worldwide rollout of vaccination programs –
The basic mechanism by which vaccines work is simple: Vaccines create immunity in an
individual by introducing a weakened or killed form of the pathogen that make us ill – such as
bacteria or viruses – or its toxins or one of its surface proteins. The vaccine induces acquired
immunity so that when your body encounters the real disease-causing agent it is ready to mount a
defense.
According to Aguiar (2016) with approximately 3 billion people at risk of acquiring the
infection, dengue fever is now considered the most important mosquito-borne viral disease in the
world, with 390 million dengue infections occurring every year, of which 96 million manifest
symptoms with any level of disease severity. Treatment of uncomplicated dengue cases is only
supportive and severe dengue cases require hospital intensive care. A vaccine now licensed in
several countries and developed by Sanofi Pasteur (CYD-TDV, named Dengvaxia), was able to
protect, in the first 25 months of the two Phase III, 66% of a subset of 9–16 year old participants.
However, a significantly lower efficacy (including negative vaccine efficacy) was noted for
Geneva (2018) in addition to saving millions of lives, vaccines will help prevent 24
million people in some of the world’s poorest countries from slipping into poverty by 2030,
The Harvard study, co-authored by Gavi, the Vaccine Alliance and a wide range of
partners, modelled the health and economic impact of vaccines for ten diseases in 41 developing
countries.
Vaccines will have the greatest impact on reducing cases of poverty caused by hepatitis
caused by measles and meningitis A will also be significantly reduced by vaccines, with an
estimated 5 million and 3 million cases averted respectively, while rotavirus is set to prevent
242,000 cases. Measles vaccine is estimated to prevent by far the highest number of deaths: 22
quarter of deaths prevented by vaccination. The researchers therefore concluded that the
introduction of vaccines in the poorest regions will have the greatest impact on reducing both the
number of deaths and the number of people forced into poverty by the cost of healthcare. The
study underlines that sustained investments in vaccines could therefore make a large contribution
toward achieving the Sustainable Development Goals and universal health coverage.
Gavi currently supports vaccine programmes in all 41 countries included in the study, which
The countries were selected based on the availability of data from Demographic and
Health Surveys. The researchers made their conclusions after estimating the distribution of
vaccine-averted deaths for each disease and simulating monthly household income for each
income group.
Johns Hopkins University (2016) also published in Health Affairs, found that for every
US$ 1 spent on immunisation, US$ 16 is saved in healthcare costs, lost wages and lost
productivity due to illness. Taking into account the broader benefits of people living longer,
healthier lives, the return on investment rises to US$ 44 per US$ 1 spent.
The study was led by researchers from Harvard T.H. Chan School of Public Health and included
contributions from the Erasmus School of Economics, University of Washington, London School
of Hygiene and Tropical Medicine, Johns Hopkins Bloomberg School of Public Health, Imperial
College London, the Kaiser Permanente Washington Health Research Institute, Bill & Melinda
Gates Foundation, and Gavi, the Vaccine Alliance. The study was funded by the Bill & Melinda
Gates Foundation.
According to Larson (2019) in its 2019 new year message, WHO has named vaccine
hesitancy as one of the world’s top 10 global health threats, alongside air pollution and climate
change, noncommunicable diseases, global influenza pandemic, fragile and vulnerable settings,
antimicrobial resistance, Ebola and other high-threat pathogens, weak primary health
When you look at the list, vaccine hesitancy is directly related to most of them, with
available vaccines for flu, Ebola (albeit still not registered), Dengue (with all its struggles), and
The threats of fragile and vulnerable settings and weak primary health care both affect
hesitancy given low confidence in the system or anxieties in conflict settings. And, as
for antimicrobial resistance, we need vaccines more than ever as we are faced with antibiotics
While it is a stretch to relate vaccine hesitancy to air pollution and climate change, climate
change will be changing disease vectors and vaccine needs, so vaccine confidence will again
NANOCONTAMINATION
Vaccines are being under investigation for the possible side effects they can cause. In
the study of vaccines, aimed at verifying the presence of solid contaminants by means of an
The results of this new investigation show the presence of micro- and nanosized
particulate matter composed of inorganic elements in vaccines’ samples which is not declared
among the components and whose unduly presence is, for the time being, inexplicable. A
considerable part of those particulate contaminants have already been verified in other matrices
suggestive of some hypotheses correlated to diseases that are mentioned and briefly discussed.
VACCINE-PREVENTABLE DISEASES
Vaccines are among the most effective prevention tools available to clinicians. However,
the success of an immunization program depends on high rates of acceptance and coverage.
There is evidence of an increase in vaccine refusal in the United States and of geographic
refusal) are at increased risk for measles and pertussis and can infect others who are too young to
be vaccinated, cannot be vaccinated for medical reasons, or were vaccinated but did not have a
sufficient immunologic response. Clinicians can play a crucial role in parental decision making.
Health care providers are cited as the most frequent source of immunization information
discontinued or have considered discontinuing their provider relationship with patients who
refuse vaccines, the American Academy of Pediatrics Committee on Bioethics advises against
this and recommends that clinicians address vaccine refusal by respectfully listening to parental
The Vaccine Testing Center's team of scientists and researchers are committed to solving
the world’s most pressing infectious disease challenges. Our research spans the translational
Together with national and international collaborators and local volunteers, we help
develop vaccines to address global infectious diseases, including rotavirus, cholera, dengue and
other flaviviruses.
CONFIDENCE ABOUT VACCINES IN THE UNITED STATES: UNDERSTANDING
PARENT’S PERCEPTIONS
Vaccines represent one of the greatest achievements of science and medicine in the battle
against disease. In the United States, the high vaccination rate for routinely recommended
immunizations for infant and childhood diseases has brought about dramatic declines in the
incidence of polio, measles, mumps, rubella, Haemophilus influenzae type b, hepatitis, and
varicella (chickenpox). In the past decade, recommendations for annual influenza vaccination
have been expanded to encompass all children six months to eighteen years of age, and new
vaccines have been added to the immunization schedule to help protect infants from rotavirus
Some experts see the prevalence of concerns, fears, and misinformation about vaccines in
new and traditional media as an indication of declining confidence in vaccines, both in the
United States and internationally. Other signs of reduced confidence in the United States include
survey data indicating that many parents question health care providers during children’s
immunization visits and reports that children’s vaccinations are delayed; books and articles
advocating alternative vaccination schedules; the relatively low vaccination rate during the 2009
H1N1 (swine influenza) pandemic; and increases in the availability and use of exemptions to
immunization program in the United States has resulted in new generations of parents who have
little or no firsthand experience with most of the diseases that are preventable by vaccination.
This study examines the notions of confidence in vaccines and hesitancy about their use,
building on recent efforts to understand parents’ beliefs and behaviors related to routinely
recommended childhood immunizations. Using data from the 2010 HealthStyles survey of
consumers, this study focuses on parents of children age six years or younger. To look for signs
of reduced vaccine confidence or increased immunization hesitancy, the study examines the
parents’ immunization intentions and behaviors, concerns about vaccines, and ways of finding
The Institute of Medicine (IOM) noted that a successful immunization program requires
financing of vaccines and of their delivery; surveillance of vaccine coverage, adverse events, and
disease; and implementation of interventions that maximize vaccine impact—all of which rely on
The introduction of new vaccines that cost more than “traditional” vaccines has highlighted
weaknesses in the current mechanisms for financing immunizations and raised concerns about
This article reviews the history and current situation of financing of vaccines and of their
administration. Child and adult immunization will be dealt with separately. The article does not
2.6 Synthesis
In a country where a quarter of its population, roughly over 25 million people, live in
poverty and cannot afford decent meals, let alone avail themselves of health services, preventing
infections and diseases is the best strategy to ensure that people stay healthy and in good
condition.
It is a widely accepted practice in the world, yet many still doubt if it is safe and effective.
a particular disease. Immunization service is one of the most important and equitable
preventive health care service made available even to population in areas that are hardest to
reach. Each year, millions of children and adults are receiving vaccinations that help protect
them from infectious, sometimes deadly, vaccine preventable diseases. These include, but not
limited to, polio, measles, tetanus, Hepatitis B, Rubella, diphtheria, pertussis, pneumonia, and
others.
As it prevents disease, disability and deaths, immunization also contributes to
economic growth. During outbreaks, the public health system spends time tracing potential
contacts, collecting and testing blood samples, engaging the public for awareness and
dissemination of information, and organizing outbreak response and money for hospital
treatments. Immunization helps remove the burden both from the health system and most
The Philippine government first approved the vaccine’s use in December 2015, along
with Mexico and Brazil. Eight other countries followed suit in 2016, namely, El Salvador,
Costa Rica, Paraguay, Guatemala, Peru, Indonesia, Thailand and Singapore. By October
2017, the vaccine had been approved in 19 countries. More than 700,000 schoolchildren, nine
years old and above, in Metro Manila, Central Luzon and Calabarzon, have received at least
the first of three injections of this first-ever licensed dengue vaccine. It is natural for parents
to worry. In all likelihood, the parents won’t allow their children to get the next injections.
More importantly, they will want to know what recourse they have in the event of a dengue
infection.
more parents are refusing to avail of the government’s various vaccination programs
This is a very complex issue — one that involves longstanding debates in medical
research, public health policy, corporate profitability and responsibility, and politics. It is
extremely important for us to fully understand the terms of this latest clinical finding before we
facts to people. Why? Because the researchers want to inform the parents and guardians that
vaccination has a huge contribution to our life because it help us to prevent some of the diseases
that may cause or result danger or lead us to death. The use of vaccination is very helpful and
vaccine can lead to healthy and long life. It’s natural to be afraid about the potential risks of
vaccine. Hence, one of the purpose of the researchers in conducting this study is to rebuild the
trust not only for the respondents of this study but also for all the Filipinos out there who have
been affected by the scare effect due to dengvaxia controversy. Now let us open our eyes and
mind. Let us not be afraid to our own fears and doubts just because of one mistake which is the