Pharmaceutical Industry - 2010 Yearbook - Therapeutic Market Landscape, Key Pipeline

Drugs, Top Pharma Companies and Key Mergers and Acquisitions

The Cardiovascular, Oncology And Central Nervous System (CNS) Therapeutics

Account For More Than 50% Of The Total Sales

Cardiovascular, oncology and CNS therapeutics accounted for more than 50% of the total
pharmaceutical market by indication. The three therapeutic segments accounted for 52%
of the total pharmaceutical market. Cardiovascular disorder therapeutics accounted for
19% of the total market share, closely followed by oncology therapeutics with 18% and
CNS therapeutics with 15% of the total pharmaceutical market share. These three major
indications contribute the most to the total pharmaceutical market.

The high market share of cardiovascular, oncology and CNS therapeutics indicates that
these therapeutic areas will decide the way forward for the global pharmaceutical
industry. Majority of the pharmaceutical companies deal in these three therapeutic areas
and their endeavour has been to increase and consolidate their portfolio in these
therapeutic areas.

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Strategic consolidations by major pharmaceutical companies are changing the global

pharmaceutical market scenario. The major mergers and acquisitions (M&A) deals of
2009 were acquisition of Wyeth by Pfizer, Genentech by Roche and the merger of Merck
and Schering-Plough. The dynamic nature of the pharmaceutical industry is expected to
continue because patent expirations of major blockbuster drugs will lead the
pharmaceutical companies to consider strategic consolidations to maintain their market
position and, to have pipeline drugs. Pharmaceutical companies need to find alternative
options to maintain their revenue generation and this can be done by acquiring regional
and niche players. It is important for pharmaceutical companies to plan for the long term,
so that the slow pace of research and development (R&D) can be objectively managed.
The acquisition of small and niche pharmaceutical companies by major pharmaceutical
companies show a very dynamic future scenario in the pharmaceutical arena.

The contribution in M&A deals involving oncology to the total value of M&A deals was
35%. This signifies that the oncology therapeutics area witnessed M&A deals of the
highest value. This was followed by cardiovascular and CNS therapeutics contributing
20% and 19% respectively to the total value of M&A deals.

More than 70% of the total value of M&A deals was from oncology, cardiovascular and
CNS therapeutics. This indicates the high value of M&A deals in oncology,
cardiovascular and CNS therapeutics.
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