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Running Head: DISORDERS OF MORTALITY

Disorders of Motility

Name

Institution
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DISORDERS OF MORTALITY

Gastric acid stimulation and production.

Gastric juices in the body are the digestive fluids that are secreted in the stomach and will

be used to break down the solid food and kill the bacteria in the stomach. The diet we take or the

drug one takes may cause some imbalances in the amount acid produced. The gastric acid will be

produced by the parietal cells that are found on the walls of the stomach. The secretory

canaliculus is a region in the parietal cell that is the most acidic part of the human body.

During the normal secretion and production, the parietal cells will be stimulated to

produce the gastric juice. The main stimulus for the gastric acid secretion is Histamine 2

receptors. Peptic ulcer disease (PUD) will cause the lining of the stomach to break which lead to

the gastric ulcer. Gastroesophageal reflux disease, on the other hand, is a digestive disorder that

will affect the esophagus sphincter. Gastritis disorders on the hand are the inflammation of the

lining of the stomach. The above three disorders in individuals will affect the gastric acid

secretion and production. Disorders will lead to gastric acid hypersecretion which is an excessive

formation of the gastric juice and the acidic component. (Rubenstein& Chen, 2014).

Factor that impacts the pathophysiology of GERD, PUD, and gastritis.

The factor selected is Gender. It is good to understand the gender and sex of individuals

before treatment of GERD, PUD, and gastritis disorders. In gastroesophageal reflux disease

(GERD), gender –related differences may affect the prevention and treatment of the disorder;

this is because of the biological factors that are different between men and women. GERD will

affect more women than men. Treatment of gastroesophageal reflux disease (GERD) involves

modification of lifestyle mostly among ladies and control of the gastric acid secretion in
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DISORDERS OF MORTALITY

individuals by use of medical therapy. If the case is serious surgical treatment may be offered. (

Lee, 2014).

Peptic ulcer disease (PUD) disorder is more common to male as compared to female. The

difference is caused by the lifestyle and the prevalence. PUD prevalence in women has got a

shorter lifetime as compared to men. Treatment of will vary depending on the clinical

presentation .The most common treatment option will be empirical secretory therapy.

(Rubenstein& Chen, 2014).

Gastritis disorder is more common in male compared to female. Those males with

gastritis are also at risk of developing other disorders such as peptic ulcer diseases. Females have

a faster ulcer healing capability as compared to males. Gender differences will, therefore, play a

greater role in the treatment and prevention of gastritis disorder. Use of antacids such as H-2

blockers will mostly be used in females than in males to treat the disorder. Males will mostly be

given some medication that is aimed at reducing the acid production.

Mind map for gastritis

Gastritis is a disorder that is an inflammation and erosion of the stomach lining and

occurs gradually in individuals. The disorder mostly affects individuals who are 60 years and

above mostly males. It is mainly caused by consumption of alcohol, stress, use of certain

medication and chronic illnesses. Major symptoms are loss of appetite, nausea, and vomiting,

(Feng, et al.2013)
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DISORDERS OF MORTALITY

H&P
Inflation of
gastric mucosa Biopsy

Erosion of Diagnosis and

epithelium Pathophysiology treatment Behavioral
modification
Acute Vs.
Gnawing &
chronic
Gastritis burning pain

Fundal Vs.
astral Epigastria pain

1-2.1 million Clinical

visits to the Nausea
presentation
Epidemiology
doctor yearly

Vomiting
Common to
people 60+
Worsen with
eating
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DISORDERS OF MORTALITY

References

Lee, S. W. (2014). The risk factors and quality of life in patients with overlapping functional

dyspepsia or peptic ulcer disease with gastroesophageal reflux disease. Gut Liver, 8(2),

160-164.

Feng, Z., Huang, J., Xu, Y., Zhang, M., & Hu, S. (2013). Dissociative disorder induced by

clarithromycin combined with rabeprazole in a patient with gastritis. Journal of

International Medical Research, 41(1), 239-243.

Rubenstein, J. H., & Chen, J. W. (2014). Epidemiology of gastroesophageal reflux disease.

Gastroenterology Clinics of North America, 43(1), 1-14.