Dr Ízaro López García

BES La Salle

www.organisol.eu
 What is Nanotechnology
 In Technology, Size Matters
 Top Down vs Bottom Up Nanomaterials Manufacturing
 Impact Of Nanomaterials On End-product Manufacturing Line
 The Business Environment
 Commercialisation Process
 Nanotechnology Value Chain
 Case Studies along the Value Chain
 The Stakeholders Environment
 Health, Environment and Safety Risks
 Regulatory Environment
 Future of Technology Business Leadership

www.organisol.eu
And why we need it.

www.organisol.eu
 Not “nano” by accident
Really small

The purposeful engineering of matter and

structures at scales of less than 100 nanometres
to achieve size-dependent properties and
functions.
Not just “small” but “small”
and “different”

www.organisol.eu
In Technology, Size
Matters

One of the most

difficult things to
understand about
nanotechnology is to
get a solid grip of
exactly how small
nanoparticles are. This
image seeks to better
illustrate this by
comparing nano sized
objects with the size of
an ant, mite, hair, red
blood cell and DNA
strand.

www.organisol.eu
Let’s see some examples...
www.organisol.eu
Nanotech in Fashion

Improved Fabrics:
• Anti-wrinkle clothes
• Resistant to:
•Dirt, water, oils, chemicals
• Antibacterial
• Sensor enabled
• Impact resistant
• Colour changing
• Odour neutralising

Companies
Dockers, Pro-Idee GmbH & Co.,
Sharper Image, Green Tee
Apparel, Outlier, Jack Wolfskin,
Speedo, Orca, Lee Jeans,
Sensatex, First Armour Choice,
P2i

Sectors
Military, Healthcare, Security,
Consumers

www.organisol.eu
Nanotech in Pharma

Improved drugs:
• Target delivery
• No side effects
• Antibacterial coatings

Diagnostics:
• Lab-on-a-chip (biofinger)
• High resolution detection
•
•
Companies
Epeius Biotech, Abtech
Scientific, AcryMed,
Nanocopoeia, NanoLogix,
Nanospectra Biosicences,

Sectors
Healthcare, Pharma

www.organisol.eu
Nanotech in Transport

Improved Materials:
• Light weight, high strength
• Resistant to:
•Dirt, water, oils, chemicals
• Super-hydrophobic
• Sensor enabled
• Impact resistant
• Radio & microwave invisible
• Non abrasive lubricants

Companies
Yamaha, Eagle One, Green
Earth Technologies, Daihatsu,
DaimlerChrysler, Yokohama
Tire Corporation, Airbus,
Boeing, Lockheed Martin,

Sectors
Defence, Aerospace,
Consumers, Automotive

www.organisol.eu
TOP DOWN
 Traditional workshop or
nanofabrication methods used
to cut, mill, and shape materials
into the desired shape and order.
 Nanopatterning techniques,
such as photolithography and
inkjet printing belong to this
category.
 These approaches utilize
technologies descended from
solid-state silicon methods for
fabricating microprocessors.
 Requires no conceptual change
in manufacturing methods
BOTTOM UP
 Molecular building blocks used to
manufacture larger components
 Using the chemical properties of
single molecules to cause single-
molecule components to self-
organize or self-assemble into
some useful conformation, or rely
on positional assembly.
 These approaches utilize the
concepts of molecular self-
assembly and/or molecular
recognition.
 Able to produce devices in parallel
and much cheaper than top-down
methods
www.organisol.eu
 Much of the cost of adopting nanomaterials is in the updating of
the manufacturing lines
 Some sectors (eg. Aerospace, automotive) are under pressure
from legislation/market and require special certifications, taking
money and time to adopt
 Some of the changes, also require training and skilled personnel
 There is a lack of modelling tools for the use of nanomaterials in
product design.

www.organisol.eu
 Conventional manufacture technologies are in their early
stages, having a negative impact on the environment.
 Bottom-up nanotechnology will produce effectively no waste
and not involve any cutting, grinding, sanding, melting,
forging, or herding of large numbers of unruly atoms.
 Computers will ultimately control the direct "printing" of any
item via an assembler straight from data using pure feedstock
atoms or molecules.
 Nanotechnology will make exactly what it is expected to and
therefore no pollution. Matter will be used more efficiently by
this technology and put to much better use; rather than just
taking up mass and space, objects will become multi-
functional, intelligent and atomically precise.
www.organisol.eu
Nanotech’s impact gets broader & deeper, eclipsing established techs

www.organisol.eu
www.organisol.eu
 Intermediate Finished Goods
Nanoscale structures
Products with Incorporating
in unprocessed form
nanoscale features Nanotechnologies

• Nanoparticles • Coatings • Cars

• Nanotubes • Fabrics • Clothing
• Quantum Dots • Memory & Logic Chips • Airplanes
• Fullerenes • Contrast Media • Computers
• Dendrimers • Optical Components • Consumer Electronics
• Nanoporous • Orthopedic Materials Devices
Materials... • Superconductive Wire... • Processed Food
• Plastic Containers
• Appliances...

www.organisol.eu
Case Study: Nanomaterials – Nanocyl
one step ahead of
competitors

 2002 Founded as a spin-off from the Universities of Namur and Liège.

 2003 Contract aquired to develop printing material for Flat Screens.
 2004 Pilot CNT plant to validate previous work, and to assess its ability to
shift to an industrial production scale.
 2005 Demonstration of industrial production feasibility
First commercial use of Nanocyl™ NC 7000 in the Electronics sector.
European producer of Nanocyl invests human and financial capital to achieve ISO 9001
certification and meet global industrial standards for quality control.
industrial-grade MWNTs
 2006 Nanocyl moves to the industrial phase for CNT production.
for electronics packaging Launch of the PLASTICYL™ range of products.
and automotive fuel
 2007 Completion of Industrial Building.
system components; now First commercial use of Nanocyl™ NC7000 in the Automotive sector.
offering polymer-MWNT  2008 Production of plastic compounds at the industrial level.
composites EPOCYL™, THERMOCYL™ and AQUACYL™ product families.
 2009 Increase in total compounding capacity.

www.organisol.eu
Case Study:
outreach along value chain
Products are based on
hybrid polymer coating
formulations enhanced by
nanoparticles, offering
properties like abrasion
resistance, hydrophobicity,
and corrosion protection;
has established product
lines in automotive
tribological coatings, easy-
to-clean glass and
ceramics, and sport and
leisure products like
ski wax
Nanointermediates – Nanogate
 1999 Stablished as a spin-off from the Leibnitz Institute for New Materials
 2000 Takeover/integration of Colloid Surface Technologies GmbH’s business
activities
 2001 Subsidiary Nanogate Coating Systems GmbH founded
 2002 Stake acquired in Holmenkol Sport-Technologies GmbH & Co. KG
 2003 Surface technologies pooled within Nanogate Coating Systems GmbH
 2004 Nanogate Advanced Materials GmbH established
 2005 Decision to transform Nanogate Coating Systems GmbH into a stock
corporation
 2006 Company renamed Nanogate AG
IPO (18.10.2006, Deutsche Börse)
 2007 Launch of the strategy programme NEXT
 2008 Majority stake acquired in Holmenkol AG
Nanogate Advanced Materials GmbH acquired in full Subsidiary FNP GmbH
established
 2009 Launch of comprehensive innovation offensive
Stake acquired in sarastro GmbH
 2010 Majority stake acquired in GfO Gesellschaft für Oberflächentechnik
Further development of Nanogate Advanced Materials GmbH to Nanogate
Industrial Solutions GmbH with focus on industrial surfaces
www.organisol.eu
Case Study: Nanointermediates – Cambridge
adsorbed for its unique IP
portfolio
Display Technology

 1992 Founded by Cambridge University and seed venture capital.

 1996 Secures first licensees (Philips and Uniax).
 1997 Receives investment of over $10 million by a financial group and Intel.
Bought by Sumitomo
Chemical in 2007; still  1999 Kelso Investment Associates and Hillman Capital acquire a majority
interest in CDT for a total of $133m.
developing polymer
 2000 CDT and Seiko-Epson demonstrate the world's first full colour active
OLEDs; partners and matrix ink-jet printed PLED display.
customers include Philips,  2002 First high profile commercial PLED product by Philips.
Seiko Epson, and DuPont. Acquisition of Oxford-based Opsys Limited.
 2003 Sumitomo Chemical and CDT form joint development project to create
high efficiency materials using dendrimer technology.
 2005 CDT grants Add-Vision Inc. (AVI) a license to certain CDT IP.
 2007 CDT acquires the assets of Next Sierra, Inc.
CDT demonstrates a 160 ppi, wide format, three-inch, full-color display
incorporating CDT's P-OLED technology.
Sumitomo Chemical Company completes acquisition of CDT for $12
per Share, on the 19th of September 2007.

www.organisol.eu
Case Study:
regaining competitiveness
under market pressure
Early adopter of
nanocomposites to enhance
shoes cushioning, now uses
different nanotechnologies
to enhance most of its high
performance products and
some consumer good, like
surface nanostructures,
enhanced fabrics and smart
sensor nano-arrays.
Nano-enabled products – Nike
 2000 First appearance of nanoengineered soles increasing the
cushioning properties of Nike’s training shoes.
 2003 Nike Sportswear releases water/dirt resistant clothing line.
 2005 Odourless fabrics start to be used in high performance sportswear
for competitions.
 2009 Nike and P2i released the Lunar Wood TZ superhydrophobic
trainer.
 2010 Develops shoes with sensor systems that could improve training
responses and control.
www.organisol.eu
The 2004 to 2007 time period
marked the first phase of emerging
nanotechnology development, as
key innovations made their first big
commercial splashes. We see this
time as the first of three phases of
emerging nanotech adoption, each
with unique characteristics.
2004 to 2007: Incorporation into
initial products driven by
manufacturing and materials
2008 to 2011: Broadening into
more new product categories
across all sectors
2012 to 2015: Deepening impact
from new innovations in existing
applications

www.organisol.eu
Risks and Legal Framework

www.organisol.eu
 The catch-all term ”nanotechnology” is so broad as to be ineffective as a
guide to tackling issues of risk management, risk governance and
insurance.
 Currently a standardization process is under way to define nanoparticles and
their associated risks.
 Health, environment and safety risks concerns are related to free
nanoparticles.
 relevant only for a certain portion of the widespread applications of
nanotechnologies.
 The implications of the special properties of nanoparticles with respect
to health and safety have not yet been taken into account by regulators.
 Size effects are not addressed by EU’s REACH policy.
 Governments starting to tackle these.
 Over the next few years, more and more consumers will be exposed to
manufactured nanoparticles.
 Labelling requirements for nanoparticles do not exist.
 Studies on biopersistence, bioaccumulation and ecotoxicity have only just
started.
www.organisol.eu
Stealth Success, Broad Impact

www.organisol.eu
Nanotechnology – and the nanomaterials that are the
root of the value chain – has taken hold in many
industries, as corporate, government, and venture capital
funding have driven spending on nanotech R&D to $13.5
billion. Despite some applications that failed to live up to
the hype, emerging nanotechnology was used in $147
billion worth of products in 2007, and will impact $3.1
trillion in manufactured goods in 2015. Large companies
are taking a more selective approach to nanotech, while
concerns that have hampered the field – like potential
environmental, health, and safety risks, and misbegotten
specialist strategies – are moving towards resolution.

www.organisol.eu
 is a consultant and partner at Organisol, which he cofounded in 2008. He provides
specialised consulting services to companies and institutions focused in
nanotechnology applications and open innovation strategies.

Ízaro can be reached at:

email: izaro@organisol.eu
Fax: +34 917615112
Mob: +34 677567771

For more information read:

 Opportunities and risks of Nanotechnologies (OECD - 2006)
 Nanotechnology, an overview based on indicators and statistics (OECD - 2009)
 Nanotech Report 5th Edition (Lux Research - 2007)
 ObservatoryNANO Report (www.observatorynano.eu)

www.organisol.eu