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This document discusses various artifacts that can arise in hematology laboratory tests from pre-analytical factors. Some examples of in vivo factors discussed are hemodilution from posture or pregnancy, which can cause pseudoanemia, as well as increased lipids, bilirubin or monoclonal proteins, which can interfere with certain assays. Red blood cell abnormalities like spherocytes or increased white or red blood cells are also discussed as potential sources of artifacts. The experienced pathologist understands when test results represent artifacts rather than true medical findings.
This document discusses various artifacts that can arise in hematology laboratory tests from pre-analytical factors. Some examples of in vivo factors discussed are hemodilution from posture …