REVIEW OF RELATED LITERATURE

In the proposed study of the researchers, Aratiles (Muntingia calabura) was used

as the main component of the said study. Aratiles contains the assets of being

antispasmodic and emollient. The plant also comprises anti diabetic properties, as

proven by Maria Isabel Layson in her previous findings. The anti-diabetic benefits of the

plant were the main focus of the researchers in their study. Given the circumstance that

the purpose of the researchers is to make a powdered sugar that would assist those

with ailments, especially those with diabetes.

Prior researches, also the same as conducted by Layson, indicate that Aratiles

was found to contain advantageous bioactive compounds, which are the following.

Polyphenols, are category of compounds that behaves as an antioxidant, consequently,

they nullify damaging free radicals that is more likely to increase an individual’s chances

of acquiring cancer, heat diseases and especially diabetes. A type of this is the

flavonoid, a plant compound commonly found in fruits and vegetables. These are

diverse group of phytonutrients (Chemicals of plants). These compound would more

likely work in the body by corralling cell-damaging free radicals and metallic ions, they

go beyond how anti-oxidants works. They modulate lipid peroxidation and prevent

inhibition of lipoproteins. And also Anthocyanin, a type of flavonoid also behaving the

same way as flavonoid with anti- inflammatory, and anti viral benefits. All of which are

anti-oxidants that is discovered by Layson’s experiment.

 Additionally, the same research proposed that Aratiles also has benefits aside

from the anti-oxidants that would relief gout, lessen uric acid, helps in proper function of

the brain, reduces blood pressure and also can be used as a pain killer. Lots of potential

was found in this small fruit even having the possible components that will prevent

cancerous tumor growth. The subsequent component that the researchers are to use is

the Ashitaba, a green leafy herb that is also known as the “tomorrow’s leaf”. Ashitaba

was found to be used by Japanese people as a medication for flu, liver problems,

arthritis, indigestion, fever, and infection as indicated in a prior study and blog of Joe

Cohen, BS. Additionally, Ashitaba is considered as an intricate herb that contains fiber,

calcium, Iron, Magnesium and many more. Chalcones, Chlorophyll, Lutein, and

Catechin are compounds that are said to be discovered in ashitaba. Lots of health

benefits are claimed in ashitaba though evidences were insufficient and inadequate

making those researches limited and low quality clinical studies. Cohen suggested in

the blog that Ashitaba should not be used as a replacement for medications that are

approved. He stated that a consultation is still required before taking ashitaba

supplements. Though there is a study that was shared in WTQ Tea Lifestyle that

ashitaba is a great treatment for Diabetes or Insulin dependent people. Making ashitaba

suitable for the purpose of the researcher’s study, which is to aid those who are insulin

dependent and make a sugar that will not trigger damaging effects on their ailments.