Beruflich Dokumente
Kultur Dokumente
chapter
twelve
Introducing new
technologies
Rebecca Rosen
Introduction
The locations in which health care is provided are constantly changing. Devel-
opments in medical technology allow selected services, previously provided
only in hospitals, to be offered in community clinics, mobile health units and
in patients’ own homes. Despite this, hospitals still house the majority of
high-cost equipment, as well as complex services such as intensive care, organ
transplantation and oncology services. This chapter uses case studies from the
National Health Service (NHS) in England to examine the role of hospitals in
relation to adopting technology, and to study the extent to which adopting
technology is linked to evidence of clinical and cost-effectiveness. It considers
what might be an appropriate role for hospitals, when multiple new technolog-
ies are emerging but health care resources are scarce. This chapter adopts a
utilitarian perspective, in which maximizing the health benefits obtained from
scarce resources is considered a desirable policy objective. The argument is that
decision-making on new technologies should be informed by high-quality
research evidence on clinical and cost-effectiveness.
The chapter starts by reviewing the main groups of emerging technologies
that may alter the role of hospitals in the future. The case studies are then
presented and implications for the role of the hospital are discussed. Ques-
tions are raised about the extent to which hospitals should aim to maximize
the clinical and cost-effectiveness of the services they offer and the mechan-
isms they might use to do this.
The US Office of Technology Assessment (1976) broadly defined medical
technologies as ‘all the drugs, devices and medical and surgical procedures
and the organizational and support systems used to provide them’. The prob-
lem is to decide what is meant by ‘new’ in relation to medical technologies:
entirely new products or techniques (such as the anti-impotence drug sildenafil
Introducing new technologies 241
Any review of the main groups of emerging medical technologies and their
potential effect on the role of the hospital is necessarily speculative, because
little research exists on the effect of different types of new medical technology
on local health systems.
Major technological advances have been made over the last decade in screen-
ing, diagnosis, treatment and palliation through developments in drugs, tests,
equipment and surgical techniques. Further advances have been seen in
hospital and community support systems, allowing organizational innovations
that change how hospitals are used. Emerging technologies can be clustered
into broad groups, each of which affects health services differently. The most
important of these are as follows.
• Screening technologies. Blood or tissue testing (for cystic fibrosis carriers) and
image-based screening technologies (ultrasound testing for aortic aneurysms)
are applied to populations of well people.
Testing technologies near the patient. Micro-assay test kits offer on-the-spot
screening and diagnosis (for example, cholesterol tests and pregnancy tests).
Drug delivery technologies. New types of drugs using immunological, pharmaco-
logical and biochemical technologies are designed to affect only specific-
ally targeted cells and tissues. In addition, drug delivery equipment such as
electronically controlled syringe drivers, trans-dermal delivery systems and
implantable drugs allow slow release over longer periods.
• Drug technologies. Multiple new drugs, such as ulcer-healing drugs, have
replaced the need for hospital-based intervention; others offer treatments
supplementary to primary therapy and appear to improve survival (for
example, tamoxifen in breast cancer), while others, such as new immuno-
suppressive drugs for organ transplantation, allow treatment of previously
untreatable patients.
• Gene therapies. Artificial introduction of genetic material may replace deleted
or defective genes. Therapy for cystic fibrosis illustrates the potential for
this treatment modality, although progress is being slowed by the hunt for
effective delivery systems.
• Laparoscopic and minimal-access surgical techniques. These techniques generally
result in shorter admissions, more rapid recovery and reduced thresholds
for intervention, with consequent increases in numbers treated.
242 Hospitals in a changing Europe
How do new technologies affect hospital services? This question can only be
given brief consideration here to illustrate the dynamic nature of technological
development, the ripple-effect on hospital and community services and the
difficulty of predicting the financial impact of new technologies. Box 12.1
outlines the varied technological developments that have changed the man-
agement of peptic ulcers over the last 10–15 years.
The effects of this string of medical technological developments can be
considered from several perspectives. From the hospital viewpoint, a complex
surgical procedure, usually reserved for patients with severe symptoms, has
largely been replaced by minimally invasive diagnostic endoscopy conducted
on many patients in day-case centres. However, drug treatment for peptic ulcers
is often long term, requiring repeated input from general practitioners with re-
referrals to endoscopy clinics and hospital specialists for some patients.
From a financial point of view, the change from occasional complex surgery
to frequent endoscopic diagnosis has required hospitals to invest in endoscopy
244 Hospitals in a changing Europe
1970s and early 1980s: Open surgery to bowel and/or associated nerve supply was
the main treatment.
Mid-1980s: Widespread use of new H2 antagonist drugs to diminish acid secretion
dramatically reduced surgical treatment and increased management by general
practitioners.
Mid-1980s: Rapid developments in endoscopy, short-acting anaesthetics and
muscle relaxants precipitated a switch of diagnostic technique from X-ray (barium
swallow) to gastroscopy or duodenoscopy. Hospitals allowed direct referral for
endoscopy by general practitioners without specialist referral, thus increasing
numbers of patients and the use of hospital day-case facilities.
Late 1980s and early 1990s: Helicobacter pylori was recognized as a common cause
of peptic ulceration. Blood tests were developed to identify the organism and the
recommended antibiotic therapy, avoiding the need for hospital services in some
patients and improving the treatment of those diagnosed through endoscopy.
suites and to train specialist staff. Furthermore, the diagnosis and post-treatment
assessment of peptic ulcer disease creates considerable work for pathology
services. In addition, the technological developments incur extra costs for
general practitioners, whose workload has increased through their greater
involvement in diagnosis, eradication therapy and ongoing symptom control.
Murphy (1998) has compared the costs of treating peptic ulcer disease using
different approaches to diagnosis, treatment and follow-up, concluding that
overall costs have increased with the advent of drug treatment. Although com-
paring the costs of historical and contemporary treatments presents methodo-
logical problems and Murphy’s study did not apportion costs to hospital and
community services, it highlights the difficulties of assessing the financial
impact of new technologies on hospitals. Overall, the case of peptic ulcer dis-
ease demonstrates how a cluster of technological developments alters the use
of hospital and community health services over time. It also highlights how
intervention thresholds change when a new technology simplifies diagnosis
and treatment, reducing the cost of treating individual patients but, in the
absence of narrow patient selection criteria, increasing the number of patients
treated and thus overall spending.
The rapid diffusion of new technologies has long been blamed for increasing
health care costs (Altman 1979; Wordsworth et al. 1996). A key concern is
Introducing new technologies 245
that widespread diffusion occurs before any evidence of clinical and cost-
effectiveness. Studies of technology diffusion across Europe have highlighted
the wide range of factors that drive technology diffusion, including clinician
enthusiasm, media and public demand, hospital strategy for enhancing reputa-
tion and attracting good staff and inducements from manufacturers (Bos 1991;
Kirchberger et al. 1991). National policies on health care funding and organ-
ization were also noted to influence diffusion. For example, countries with
global health care hospital budgets had slower technology diffusion, whereas
big-ticket technologies diffused more rapidly in countries with large private
hospitals.
Research into the effectiveness of new technologies, also known as health
technology assessment, ranges from descriptive studies of a small number of
patients to large well-designed randomized trials or cohort studies comparing
the effects of new and established interventions. It is widely accepted that small,
uncontrolled studies are susceptible to bias and may produce misleading results,
whereas well-designed randomized trials produce reliable and valid results.
Thus, decisions to adopt technology should ideally be based on the results of
clinical trials with an associated economic evaluation.
In the case of the United Kingdom, the structure of the health care system
could be expected to influence the adoption of technology by hospitals. In
the 1990s, the National Health Service was organized into an internal market
(also known as a quasi-market and the purchaser–provider split) where hos-
pitals and community health services were provided on the basis of contracts
with purchasers (health authorities or groups of fundholding general practi-
tioners). The term ‘quasi-market’ was used because a tax-funded health system
imposed political constraints on the extent to which market forces were allowed
to determine available services. As a result, the system was highly regulated
and market forces were restricted. Health authorities are statutory bodies
responsible for assessing the health needs of a geographically defined popula-
tion and for ensuring that health services are available to meet identified needs.
During the period of the internal market, health authorities used contracts
with providers to fulfil their responsibility for providing appropriate health
care. Provider income was mainly determined by the content of contracts
with purchasers.
This organizational arrangement was important because it created the theor-
etical possibility that purchasers could create financial incentives to influence
the clinical activity of providers. As advocates for the health of the geographically
defined population they serve, health authorities aimed to maximize the health
improvements obtained from the scarce resources they were allocated. In theory,
they could use the contracting system of the internal market to restrict pay-
ment for, or allocate funding to, specific new technologies, according to whether
available research evidence suggested they were clinically cost-effective.
The following case studies illustrate the role of hospitals in decisions about
introducing new technologies and examine the extent to which National
246 Hospitals in a changing Europe
Methods
The case studies examined the introduction into National Health Service acute
hospitals of three contrasting new medical technologies: vascular stents, the
triple test (testing for alpha-fetoprotein, human chorionic gonadotropin and
unconjugated estriol) and the excimer laser. Stents are small metal tubes that
can be inserted by interventional radiologists and used to support arteries
after angioplasty, thus avoiding the need for open surgery. The triple test is a
pre-natal, three-part screening blood test to assess the risk that a foetus is
affected by Down’s syndrome. The excimer laser is used for the treatment of
short-sightedness and some corneal disorders in the eye. Each technology was
studied in three different hospital or health authority sites, including teaching
and non-teaching hospitals and adopters and non-adopters of the technologies
(nine study sites in total).
Data were collected through 51 semi-structured interviews with clinicians,
managers and public health physicians working in the hospitals and their
associated health authorities who had been involved in introducing these
technologies. In four of the nine study sites, documentary records (archive
material, business cases, letters and memos) were made available and were
examined for consistency with verbal reports. Data were analysed inductively
and used to develop hypotheses about mechanisms for linking the introduction
of new technologies to research evidence of clinical and cost-effectiveness.
The type of technology assessment research available to the decision-makers
varied, since decisions about adoption were made at different times in each
study site. Early decisions about the triple test in one site were based only on
assessments by teaching hospitals of the accuracy of the test, whereas later
decisions were also informed by community-based studies showing lower
detection rates. Research on stenting consisted of multiple case series reports
describing outcomes and complications. At the time of the case studies, several
randomized trials were underway but had not yet reported. No economic
evaluations had been undertaken and a few poor-quality costing studies had
been published. Randomized trials of the laser were not ethically possible, but
many case series were available describing outcomes and complications. A few
poor-quality descriptions of the costs associated with excimer treatment were
available.
Findings are presented here from the case studies regarding the involvement
of physicians and managers from health authorities and hospitals (that is,
Introducing new technologies 247
Discussion
These case studies looked at three contrasting technologies for the treatment
or investigation of common health problems. The excimer laser represented
the type of high-cost technology that typically attracts the attention of health
planners (as seen with magnetic resonance imaging, computed tomography
and lithotripsy). The stenting and triple test cases were representative of the
hundreds of smaller-scale new technologies that do not require major capital
investment and therefore attract less attention from planners but are intro-
duced into clinical practice on a regular basis.
When public health physicians from health authorities were involved in
introducing the technologies, their professional commitment to improving
population health caused them to emphasize the importance of conducting
research comparing the effectiveness of new and established interventions. If
necessary, they advocated restricting use of a technology until methodologic-
ally rigorous comparative studies (that is, randomized trials or large comparat-
ive cohort studies) were available. Although clinicians were clearly committed
to assessing the impact of these technologies on patient health, they were less
concerned to base technology decisions on rigorous comparative studies but
accepted case series that described the outcomes and risks associated with the
procedure. Where hospital managers were involved in decision-making, their
main objective was to assess how the technology would affect the hospital
organization as a whole.
These studies are consistent with the findings of researchers in the United
States. Greer (1985) described three different decision systems in relation to
Introducing new technologies 249
Implications
I have argued that most decisions to adopt technology are made within
hospitals, with minimal reference to decision-makers, such as public health
physicians in health authorities, who take a utilitarian, population perspect-
ive and aim to maximize clinical and cost-effectiveness. This raises at least
two questions about the appropriate role of the hospital in relation to new
technologies. First, should hospital decision-makers routinely take a utilitarian
approach and assess whether a proposed technology is clinically effective and
cost-effective compared with current practice? If so, through what mechanisms
can such a link be strengthened?
The answer to the first question is determined partly by hospital type. One
might argue that the only important aim of a private hospital is to maximize
profits, regardless of how acquiring technology affects the overall health service;
for example, increased insurance premiums or opportunity costs for other
services or institutions. However, is a public hospital operating in a tax-funded
health system such as Sweden or the United Kingdom obligated to balance the
rights of patients to treatment and organizational viability against maximizing
health benefit to the taxpaying population? What would happen if public
hospitals were to incorporate utilitarian objectives into their decisions to adopt
technology, whereas private hospitals were not to, consequently expanding
their technology?
These are clearly value judgements, but a number of factors support the
incorporation of more utilitarian thinking into hospital decision-making. First,
as countries move away from fee-for-service payments and towards global
budgets and prospective payment systems (Spibey 1995), hospitals have financial
incentives to ensure that new technologies are cost-effective compared with
current practice. Second, interest is growing in developing a sounder evidence
250 Hospitals in a changing Europe
This model could easily be applied within European hospitals to develop the
role of the hospital in promoting the prudent use of scarce resources and the
effective use of new technologies.
References
Altman, S. (1979) Medical Technology: The Culprit Behind Health Care Costs? Washington, DC:
US Government Printing Office for the Department of Health, Education and Welfare.
Banta, H.D. and Oortwijn, W. (1999) Health technology assessment in the European
Union, Eurohealth, 5: 37–9.
Bos, M. (1991) The Diffusion of Heart and Liver Transplantation across Europe. London:
King’s Fund.
Bos, M. (1995) Health care technology in the Netherlands, in H.D. Banta, R.N. Battista,
H. Gelband and E. Jonsson (eds) Health Care Technology and its Assessment in Eight
Countries. Washington, DC: Office of Technology Assessment of the US Congress.
Castaneda, M. and Breivis, J. (1990) Technology assessment, Health Care Forum Journal,
November/December, pp. 10–11.
Gage, F. (1998) Cell therapy, Nature, 392(7): 18–24.
Greer, A. (1985) Adoption of medical technology: the hospital’s three decision systems,
International Journal of Technology Assessment in Health Care, 1: 669–80.
Harrison, A. and Prentice, S. (1996) Acute Futures. London: King’s Fund.
Hollingsworth, S. and Barker, S. (1999) Gene therapy; into the future of surgery, Lancet,
353: 19–20.
Kirchberger, S., Durieux, P., Viens-Bitker, C. et al. (1991) The Diffusion of Two Technologies
for Renal Stone Treatment across Europe. London: King’s Fund.
Luce, B. and Brown, R. (1995) The use of technology assessment by hospitals, health
maintenance organizations and third-party payers in the United States, International
Journal of Technology Assessment in Health Care, 11(1): 79–92.
Murphy, S. (1998) Does new technology increase or decrease health care costs? The treat-
ment of peptic ulceration, Journal of Health Services Research and Policy, 3: 215–18.
Office of Technology Assessment (1976) Development of Medical Technology: Opportunities
for Assessment. Washington, DC: US Government Printing Office.
Rosen, R. (2000) Applying research to health care policy and practice: medical and
managerial views on effectiveness and the role of research, Journal of Health Services
Research and Policy, 5: 103–8.
Rosen, R. and Mays, N. (1998) The impact of the UK NHS purchaser–provider split on
the ‘rational’ introduction of new medical technologies, Health Policy, 43: 103–23.
Schwartz, E. (1994) In the pipeline: a work of valuable technology, Health Affairs
(Millwood ), 13(summer): 71–9.
Sheldon, T. and Chalmers, I. (1994) The UK Cochrane Centre and the NHS Centre for
Reviews and Dissemination: respective roles within the information system strategy
of the NHS R&D programme, coordination and principles underlying collaboration,
Health Economics, 3: 201–3.
Spibey, J. (1995) Health care technology in the United Kingdom, in H.D. Banta, R.N. Battista,
H. Gelband and E. Jonsson (eds) Health Care Technology and its Assessment in Eight
Countries. Washington, DC: Office of Technology Assessment of the US Congress.
Weingart, S. (1993) Acquiring advanced technology: decision-making strategies at twelve
medical centres, International Journal of Technical Assessment in Health Care, 9(4):
530–8.
Wordsworth, S., Donaldson, C. and Scott, A. (1996) Can We Afford the NHS? London:
Institute for Public Policy Research.