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Renewable Energy
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Article history: In this work, an automatic fault detection method for grid-connected photovoltaic (GCPV) plants is
Received 22 May 2013 presented. The proposed method generates a diagnostic signal which indicates possible faults occurring
Accepted 29 November 2013 in the GCPV plant. In order to determine the location of the fault, the ratio between DC and AC power is
Available online 22 December 2013
monitored. The software tool developed identifies different types of faults like: fault in a photovoltaic
module, fault in a photovoltaic string, fault in an inverter, and a general fault that may include partial
Keywords:
shading, PV ageing, or MPPT error. In addition to the diagnostic signal, other essential information about
GCPV plant
the system can be displayed each 10 min on the designed tool. The method has been validated using an
Power loss
Fault detection
experimental database of climatic and electrical parameters regarding a 20 kWp GCPV plant installed on
Diagnostic the rooftop of the municipality of Trieste, Italy. The obtained results indicate that the proposed method
can detect and locate correctly different type of faults in both DC and AC sides of the GCPV plant. The
developed software can help users to check possible faults on their systems in real time.
Ó 2013 Elsevier Ltd. All rights reserved.
0960-1481/$ e see front matter Ó 2013 Elsevier Ltd. All rights reserved.
http://dx.doi.org/10.1016/j.renene.2013.11.073
100 W. Chine et al. / Renewable Energy 66 (2014) 99e110
Fig. 1. a. The GCPV plant installed on the rooftop of the Trieste local government, data-acquisition system and the designed tool. b. Example of the monitored data (Gi: irradiance, Tc:
cell temperature, output DC and AC power) for a few days (SQ3).
defect, string defect, etc.), variable energy losses (for example due Some other techniques are based on learning methods and take
to shading [9], grid disconnections, power limitation of the inverter, into account the specific condition of the plant under monitoring
MPP tracking failures, temperature, etc.), and losses due to the [12]. This type of monitoring system simplifies the operation and
presence of snow (blackout). maintenance of the PV systems, even though it needs many mea-
Other researchers used climate data measured by local sensors surement sensors. Two types of faults were identified by this
on the plants. This category includes the intelligent based ap- method: shading and inverter failure. Firth et al. [13] have devel-
proaches, as an example the method proposed by Syafaruddin et al. oped a technique that used only few measurement sensors, which
[10] that used a three layered feed forward neural network, which can classify the energy losses in four different categories: sustained
allows the identification of the short-circuit location of PV modules zero efficiency faults, brief zero efficiency faults, shading, and non-
in one string. Another intelligent system for automatic detection of zero efficiency non-shading faults. Moreover, the loss of energy can
faults in PV fields based on a TakagieSugenoeKahn Fuzzy Rule- be quantified. Nevertheless, this technique does not detect any type
Based System (TSKFRBS) was described in Ref. [11]. The results of fault leading to possible loss of energy without any alarm given.
show that the system can recognize more than 90% of fault con- Gokmen et al. [14] developed a simple diagnostic method to
ditions, even when noisy data are introduced. determine the number of open and short-circuited PV modules in a
W. Chine et al. / Renewable Energy 66 (2014) 99e110 101
Table 1
Characteristics of EC-115 evergreen module [21]. a 5000
4500
Technology Polycrystalline Si
Simulated DC power (W )
4000
Peak power 115 W
3500
Open circuit voltage at STC 21.5 V
Maximum power point voltage at STC 17.3 V 3000
Short circuit current at STC 7.26 A 2500
Maximum power point current at STC 6.65 A
Number of cells 72 2000
Nominal operating cell temperature 44 C 1500
Voltageetemperature coefficient 0.53%/ C
1000
Currentetemperature coefficient 0.049%/ C
Poweretemperature coefficient 0.49%/ C 500
0
0 500 1000 1500 2000 2500 3000 3500 4000 4500 5000
Measured DC power (W)
string with a small number of sensors. Zhao et al. [15] examined
two types of faults taking into account Over-Current Protection b 4500
Devices (OCPD). The first type of fault is the line to line one that 4000
occurs under low irradiance conditions and the second type is again
the line to line fault but this time occurring in PV arrays where 3500
its location without any additional hardware. This has the disad-
vantage of high cost and re-design problem if the inverter specifi-
AC power ratio, and the ratio between the simulated and measured
cation has been changed. An automatic supervision and fault
DC voltage and current. The fault categories identified by the pro-
detection procedure based on the power losses analysis was pro-
posed technique are:
posed in Ref. [20]. This procedure is able to detect only faults that
occur on the DC side of the PV system. The technique allows the
- faulty modules in a string;
identification of four different types of faults: faulty modules in a
- faulty string;
string, faulty string, false alarm, and a group of different faults such
- faulty inverter;
as partial shadow, ageing, and MPPT error.
- false alarm;
Based on the techniques mentioned above, we can conclude that
- group of faults which include partial shading, ageing of PVs, and
some are not automatic and give only the possible fault types (can
MPPT error.
not identify the exact location of fault), and some others can detect
only the faults occurred on the DC side of the PV system.
Moreover, the technique allows exact location of the failed
In this paper, a simple and fast automatic method is presented. It
string and failed inverter by calculating the DC current ratio of each
allows the detection of faults occurring both in the DC and in the AC
string and the AC power ratio of each inverter. Finally, a software
side of a GCPV system. Initially, the absolute error on the perfor-
tool is designed using MatLab/GUI (graphical user interface) to
mance ratio is calculated and compared with a threshold gener-
display and monitor automatically the possible faults occurring in a
ating a diagnostic signal. Subsequently, three parameters are
PV plant. Essential information about the system is also displayed
calculated and used in order to determine the type of fault: the DCe
and stored each 10 min, which permits users to check their system
in real-time. Therefore, the main contribution of present work is to
Table 2
propose a simple and fast diagnosis method for GCPV systems, to
Mastervolt inverter electrical data [21]. design a user friendly tool using MatLab/GUI and finally to verity
this method using experimental data.
Number of MPPT 4
Output voltage 230 V, 50 HZ
Nominal power 5500 W
European efficiency 94% Table 3
Maximum efficiency 95% Estimated parameters using least square algorithm.
MPPT voltage range 100e380 V
y0 c1 c2 c3 c4
Maximum DC voltage 450 V
Nominal DC current 7.5 A Estimated parameters 1.0733 1.6817 0.0721 1.8440 0.4069
102 W. Chine et al. / Renewable Energy 66 (2014) 99e110
a
Climatic data from DAQ Module parameters and plant
(irradiance+module Configuration Electrical data from DAQ
Temperature) (sec 2.1)
Simulation model of
PV module
(sec. 3.1.1)
PR_meas=Yf_meas/Yr
PR_sim=Yf_sim/Yr
Yes No
b Diagnostic signal=1
No Yes
Rp_dc_ac<1
Yes No
-Defect inverter
Rc>1
-Hot inverter
Yes No No Yes
Rv>1 Rv>1
No Yes
Rp_ac j<1
Faulty
strings
Yes No
Rvi<1
No fault in string i
String i is failed
Fig. 3. a. Flowchart of the fault-diagnosis system of the GCPV plant. b. Flowchart of the fault identification and location procedure.
W. Chine et al. / Renewable Energy 66 (2014) 99e110 103
3. Methodology
Fig. 6. a. Absolute performance ratio error and diagnostic signal evolution (no fault). b. False alarm observed in the designed software. c. DC current, DC voltage and DCeAC power
ratios evolution. 6d. No fault observed in the designed software.
AKT X
N
Vt ¼ (2) SðwÞ ¼ ðPin hðPin ; wÞÞ2 (4)
q
i¼1
where: K is Boltzmann’s constant, q is the charge of the electron,
where: w ¼ (y0, c1, c2, c3, c4) is the vector of the five parameters to be
and A is the diode ideality factor.
estimated.
These five parameters are determined by solving the transcen-
Table 3 reports the values of the estimated five parameters,
dental equation (Eq. (1)) using the NewtoneRaphson algorithm
using the input power Pin of the PV generator described above.
based only on the datasheet of the available parameters [22]. The
The model has been verified for several samples; as an
algorithm has been developed in MatLab by using the function
example, Fig. 2b shows a comparison between the AC simu-
“fsolve” available in the Optimization ToolboxÔ. The one-diode
lated and measured power. The simulated AC power is very
model given in Eq. (1), has been tested using the data collected
close to the measured one and the correlation coefficient in
during one day by the monitoring system of the GCPV plant
this case is 99%.
described in Section 2.
Fig. 2a shows a comparison between the measured and the
calculated DC power for February 2, 2009 day. A good agreement 3.2. Power losses in DC and AC side of the PV system
between the two signals has been obtained and the correlation
coefficient is equal to 98%. 3.2.1. Power losses in the DC side (capture losses)
The overall losses occurring in the DC side of the GCPV system
depend on a number of factors. Some of these are related to the PV
3.1.2. AC output model
module and others to the climatic conditions. The power losses in
The efficiency of an inverter converting the DC current and
the DC side of the photovoltaic plant are defined as “capture losses
voltage into the AC current and voltage has been modelled with the
(Lc)”. These are related to the operating cell’s temperature, solar
standard approach given by the following equation. The model
irradiance level, PV shading, and to the sunlight Angle Of Inci-
describes the efficiency as a function of the input power (Pin) [24].
dence (AOI) [20]. The capture losses are only a part of the DC
losses; other DC losses are related to the efficiency of the
hDC=AC ¼ y0 þc1 ð1expðc2 Pin ÞÞþc3 ð1expðc4 Pin ÞÞ (3) Maximum Power Point Tracker (MPPT) technique employed, to
the mismatch, wiring losses, soiling effect, etc. Nevertheless, the
where y0, c1, c2, c3, and c4, are five parameters that can be deter- capture losses are a good indicator of failures occurring on the DC
mined using a non-linear regression algorithm, such as the least side of the photovoltaic systems and they are given by the
square algorithm, minimizing the following quadratic function: following equation [25]:
W. Chine et al. / Renewable Energy 66 (2014) 99e110 105
LS ¼ Ya Yf (8)
EAC
Yf ¼ (9)
p0
Another parameter that can give a global idea of the system
behaviour is the performance ratio. This indicates the overall losses
occurring in the PV system and is defined as:
Yf
PR ¼ (10)
Yr
Fig. 8. a. Absolute performance ratio error and diagnostic signal evolution (faulty modules). b. Faulty in PV modules observed in the designed tool. c. DC current, DC voltage, and DC/
AC power ratios evolution.
array’s DC voltage, and Vpv_meas is the measured array’s DC d) If Rc < 1 and Rv < 1: it means that there are no losses on the
voltage. current and voltage; in this case the diagnostic signal state is
The DCeAC output power ratio (RPDC_AC) given by the following considered as a false alarm.
equation is introduced:
The calculation of the ratio between the measured DC current of
each string and the AC power of each inverter with respect the
PDC_sim
P simulated ones, given by Eqs (15) and (16), allows the identification
RPDC_AC ¼ P
DC_meas
(14) of the exact location of the fault string and the fault inverter.
AC_sim
PAC_meas
Ipv_measi
where PDC_sim is the simulated DC power, PAC_sim is the simulated AC Rci ¼ (15)
Ipv_simi
power, PDC_meas is the measured DC power and PAC_meas is the
measured AC power.
The analysis of the current, voltage, and power ratio allows the Pac_measj
Rpj ¼ (16)
identification of the type of faults. The failure identification method Pac_simj
is as follows:
where: i and j are the number of strings and inverters in the PV
- If RPDC_AC < 1: it means that the measured AC power is decreased plant respectively.
which indicates that there were possibilities of the inverter The fault identification and location procedure are illustrated by
stopping (or malfunctioning), or a wire between the inverter the flowchart presented in Fig. 3b.
and the grid line was broken.
- If RPDC_AC > 1: it means that the measured DC power is
decreased which indicates that a fault was occurred on the DC 3.5. The automatic fault detection tool
side of PV system, in this case we can identify four categories of
faults: In order to simplify the diagnostic procedure, this is imple-
a) If Rc > 1 and Rv < 1: It indicates that there is possibility of mented graphically under MatLab/GUI. The graphical user interface
string disconnection (or breakdown in string itself). developed can monitor instantaneously the PV plant. Its outputs
b) If Rc < 1 and Rv > 1: It indicates that there is possibility of are the state of the diagnostic signal, the values of the APRE and the
disconnection of modules in a string (or breakdown in three indicators DC current, DC voltage, and DCeAC power ratios, as
modules). well as the type and the location of fault. The inputs are the
c) If Rc > 1 and Rv > 1: It means that a fault was occurred on the measured climatic and electrical data which are loaded from the
PV array as: partial shadow, ageing, MPPT error. database, as well as the calculated data.
W. Chine et al. / Renewable Energy 66 (2014) 99e110 107
a 1.5
a 18000 APRE
Threshold
1
14000
12000
Output DC power [W]
0.5
10000
8000
6000 0
4000
1.5
10000
Output AC power [W]
8000
6000 1
4000
2000
Simulated output AC power 0.5
100 200 300 400 500 600 700 800
Measured output AC power Time (min)
0
0 100 200 300 400 500 600 700 800 900
Time [min] c
c
Fig. 9. a. PV array output power, measured and simulated results. b. Inverter output
power, measured and simulated results. c. Faulty observed in the designed tool. Fig. 10. a. Absolute performance ratio error and diagnostic signal evolution (faulty
strings). b. Current, voltage, and power ratios evolution. c. DC current ratios of each
string.
108 W. Chine et al. / Renewable Energy 66 (2014) 99e110
10000 1.6
Output AC power [W]
1.4
1.2
5000
0.8
0
100 200 300 400 500 600 700 800
Time [min] 0.6
b 1.5
APRE 0.4
Threshold
100 200 300 400 500 600 700 800
APRE, threshold and diagnostic signal evolution
1 b 2
inverter 1
inverter 2
inverter 3
1.5
0.5
AC power ratios
1
0
0.5
-0.5
100 200 300 400 500 600 700 800
Time [min]
0
Fig. 11. a. Inverter output power, measured and simulated results. b. Absolute per-
formance ratio error and diagnostic signal evolution (faulty inverter).
-0.5
4. Experimental validation of the developed system 100 200 300 400 500 600 700 800
Time [min]
In this section, the performance of the developed diagnostic c
method is verified. For this purpose, the acquired data of three
different days (e.g. February 2, 2009, May18, 2009, and May 23, 2009)
have been considered. Four case studies have been examined and
presented. Fig. 4 shows the different faults analysed in this study. The
developed software can automatically display and save the state
(normal/fault) of the GCPV system every 10 min, by making a com-
parison between monitored and calculated electrical current, voltage,
power and the different performance ratios. Monitored and calcu-
lated parameters are also displayed by the software. Moreover, at the
end of the day the user could print and check the system evolution.
As a consequence, the voltage of the string falls to a wrong value in the GCPV plant. In order to detect the failure occurred in the
and this fact impacts both the DC and the AC power. In this case, the inverter, we have defined an indicator named DCeAC power ratio,
diagnosed result is as follows: for identifying clearly the precise location of faulty string and faulty
In Fig. 7a and b, the unexpected DC and AC power is shown with inverter, by calculating the DC current and AC power ratios of each
respect to the simulated ones. Absolute performance ratio error and string and each inverter respectively. This procedure has been tested
diagnostic signal evolution are depicted in Fig. 8a, as a conse- using monitored data of a 20 kWp GCPV plant. Four case studies have
quence, the APRE exceeds the assigned threshold, and the diag- been presented: the normal operation with false signal, faulty
nostic signal is one. More details are reported in the designed tool, modules, faulty strings and faulty inverter operation. Results
Fig. 8b. In addition, Fig. 8c shows the evolution of the current, confirm the feasibility of the method for fault diagnosis of GCPV
voltage, and power ratios of the GCPV plant. Analysing the plots plants with good accuracy.
depicted in both Fig. 8b and c, some information regarding the type An automatic system is developed graphically under MatLab/
of faults can be obtained; the measured output voltage reduction GUI to display and monitor instantaneously the PV plant, and
increases the DC voltage ratio, while the DCeAC power and DC therefore, the designed software has the potential for becoming a
current ratios remain unchanged. This fact is related to the useful, widespread tool for GCPV design engineers, O&M personnel,
disconnection of modules in a string (or breakdown in modules). as well as scientists.
In the future, we aim to implement experimentally the devel-
4.3. Case 3: faulty strings oped automatic procedure into low cost microcontroller, with LCD
display and flash alarm to notify users about the state of their
In this case, the disconnection of four strings connected to the systems in real time.
first inverter has been simulated. The result is a reduction in the
current and power of the GCPV plant as can be seen in Fig. 9a and b.
Acknowledgement
More information about this fault are reported in the designed tool,
see Fig. 9c, where it is clearly shown that the measured current and
Authors wish to thank the municipality of Trieste and Mr. F.
power are lower than those simulated.
Romeo for providing the experimental data of climate and electrical
As shown in Fig. 10a, the APRE exceeds the threshold so that the
signals. Particular thanks also to Mr. L. Farneti for his efforts in
diagnostic signal goes one and the fault is detected. Fig. 10b depicts
making possible the remote access of the electrical and climate data
the current, voltage and power ratios evolution of the system, the
at the University of Trieste. Also, the second author would like to
fault type can be detected by analysing both Figs. 10b and 9c. It can
thank the International Centre for Theoretical Physics (ICTP),
be observed, that the measured current reduction increases the DC
Trieste (Italy) for providing the means and the computers facilities
current ratio, while the DC voltage and the DCeAC power ratios
for performing the present work.
remain unchanged; this means that there was a possibility of
strings disconnection (or breakdown in the same string).
The location of the four strings disconnected can be determined References
by analysing the ratio of the measured output current of each string
[1] Pacas JM, Molina MG, dos Santos Jr EC. Design of a robust and efficient power
with respect to the simulated one, as shown in Fig. 10c. electronic interface for the grid integration of solar photovoltaic generation
systems. Int J Hydrogen Energy 2012;37:10076e82.
4.4. Case 4: faulty inverter [2] Almonacid F, Rus C, Pérez-Higueras P, Hontoria L. Calculation of the energy
provided by a PV generator. Comparative study: conventional methods vs.
artificial neural networks. Energy 2011;36:375e84.
To confirm whether a failure which happens in the inverter [3] Nordmann T, Jahn U, Nasse W. Performance of PV systems under real con-
could be detected by this method, an inverter disconnection fault is ditions. In: European workshop on life cycle analysis and recycling of solar
modules, the waste challenge, Brussels 2004.
generated on the GCPV plant. Fig. 11a shows the reduction at the
[4] Takashima T, Yamaguchi J, Otani K, Oozeki T, Kato K, Ishida M. Experimental
measured AC power compared with the simulated one. As a result, studies of fault location in PV module strings. Sol Energy Mater Sol Cells
the APRE level given in Fig. 11b is higher than the expected 2009;93:1079e82.
[5] Schirone L, Schirone L, Califano FP, Pastena M. Fault detection in a photo-
threshold, and the diagnostic signal in this case equals to one.
voltaic plant by time domain reflectometry. Prog Photovolt Res Appl 1994;2:
To isolate the type of fault, we analyse the DCeAC power ratio 35e44.
shown in Fig. 12a, which has a value lower than one, and in addition [6] Vergura S, Acciani G, Amoruso V, Patrono G. Inferential statistics for moni-
the value of the DC current and voltage ratios is near to one. This toring and fault forecasting of PV plants. In: Proceedings of the IEEE inter-
national symposium, industrial electronics, July 2008, Cambridge, UK 2008.
means that there are no losses on the DC output power of the array, pp. 2414e9.
because each inverter is endowed with four Maximum Power Point [7] Drews A, de Keizer AC, Beyer HG, Lorenz E, Betcke J, van Sark WGJHM, et al.
Tracking (MPPT) systems. This information confirms that there is Monitoring and remote failure detection of grid-connected PV systems based
on satellite observations. Sol Energy 2007;81:548e64.
no possibility that a wire between modules/strings and inverter [8] Muselli M, Notton G, Canaletti JL, Louche A. Utilization of Meteosat satellite
was broken or a breakdown occurs in strings and/or modules. derived radiation data for integration of autonomous photovoltaic solar en-
Therefore, inverter stopping or (malfunctioning) is the most likely ergy systems in remote areas. Energy Convers Manag 1998;39:1e19.
[9] Drif M, Mellit A, Aguilera J, Pérez PJ. A comprehensive method for estimating
source of power loss. energy losses due to shading of GC-BIPV systems using monitoring data. Sol
We can also identify exactly the location of the failed inverter by Energy 2012;86:2397e404.
analysing the measured AC output power of each inverter with [10] Syafaruddin S, Karatepe E, Hiyama T. Controlling of artificial neural network
for fault diagnosis of photovoltaic array. In: Proceedings of the 16th inter-
respect to the simulated one as given in Fig. 12b. More details about national conference on intelligent system application to power systems
this fault are reported in the designed tool presented in Fig. 12c. (ISAP), September 2011, Greece. p. 1e6.
[11] Ducange P, Fazzolari M, Lazzerini B, Marcelloni F. An intelligent system for
detecting faults in photovoltaic fields. In: Proceedings of the 11th interna-
5. Conclusions
tional conference on intelligent systems design and applications IEEE,
November 2011, Cordoba, Spain. p. 1341e6.
A fault detection method for a grid-connected photovoltaic [12] Yagi Y, Kishi H, Hagihara R, Tanaka T, Kozuma S, Ishida T, et al. Diagnostic
(GCPV) plant based on the comparison of the APRE with a threshold technology and an expert system for photovoltaic systems using the learning
method. Sol Energy Mater Sol Cells 2003;75:655e63.
is proposed and verified experimentally. The method generates a [13] Firth SK, Lomas KJ, Rees SJ. A simple model of PV system performance and its
diagnostic signal as an indicator of normality/abnormality operation use in fault detection. Sol Energy 2010;84:624e35.
110 W. Chine et al. / Renewable Energy 66 (2014) 99e110
[14] Gokmen N, Karatepe E, Celik B, Silvestre S. Simple diagnostic approach for [20] Chouder A, Silvestre S. Automatic supervision and fault detection of PV systems
determining of faulted PV modules in string based PV arrays. Sol Energy based on power losses analysis. Energy Convers Manag 2010;51:1929e37.
2012;86:3364e77. [21] Mellit A, Pavan AM. Performance prediction of 20 kWp grid connected
[15] Zhao Y, Lehman B, DePalma JF, Mosesian J, Lyons R. Challenges to overcurrent photovoltaic plant at Trieste (Italy) using artificial neural network. Energy
protection devices under line-line faults in solar photovoltaic arrays. In: IEEE Convers Manag 2010;51:2431e41.
energy conversion congress and exposition (ECCE), Sept. 2011, Phoenix, Ari- [22] Sera D, Teodorescu R, Rodriguez P. PV panel model based on datasheet values.
zona 2011. pp. 20e7. In: Proceedings of the IEEE international symposium on industrial electronics
[16] Chao KH, Ho SH, Wang MH. Modelling and fault diagnosis of a photovoltaic 2007. pp. 2392e6.
system. Electr Power Syst Res 2008;78:97e105. [23] Stein JS, Cameron CP, Bourne B, Kimber A, Posbic J, Jester T. A standardized
[17] Miwa M, Yamanaka S, Kawamura H, Ohno H, Kawamura H. Diagnosis of a approach to PV system performance model validation. In: Photovoltaic spe-
power output lowering of PV array with a (-dI/dV)-V characteristic. In: Pro- cialists conference (PVSC), 2010 35th IEEE 2010. pp. 1079e84.
ceeding of IEEE 4th world conference on photovoltaic energy conversion [24] So JH, Jung YS, Yu GJ, Choi JY, Choi JH. Performance results and analysis of
2006. pp. 2442e5. 3 kW grid-connected PV systems. Renew Energy 2007;32:1858e72.
[18] Zhao Y, Yang L, Lehman B, DePalma JF, Mosesian J, Lyons R. Decision-based [25] Kymakis E, Kalykakis S, Papazoglou TM. Performance analysis of a grid connected
fault detection and classification in solar photovoltaic arrays. In: Twenty- photovoltaic park on the island of Crete. Energy Convers Manag 2009;50:433e8.
seventh annual IEEE applied power electronics conference and exposition, [26] Chouder A, Silvestre S. Analysis model of mismatch power losses in PV Sys-
5-9 Feb. 2012. p. 93e9. tems. J Sol Energy Eng 2009;131:024504e9.
[19] Il-Song K. Fault detection algorithm of the photovoltaic system using wavelet [27] Spertino F, Akilimali JS. Are manufacturing IeV mismatch and reverse cur-
transform. In: Proceedings of the IEEE India international conference on po- rents key factors in large photovoltaic arrays? IEEE Trans Ind Electron
wer electronics, January 2010, New Delhi. p. 1e6. 2009;56:4520e31.