Predisposing

Age

Sex

Precipitating Factor:

Occupation – Tricycle driver

Diet -

Sleep Pattern

Exposure to precipitating factors like chemicals, pollutants, and radiation exposure

Disturbed sleep pattern can depress the immune system

Irritation and damage to cell structure

As adaptive mechanisms, changes in morphology occurs

Prolong exposure to the above risk factors, the changes become irreversible causing gene mutations in
DNA

Inactivation of tumor suppressor genes, and activation of oncogenes

Uncontrolled cell division and decreased apoptosis

Hyperplasia of brain cells

Brain tumors