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Objective To investigate the relationship between mode of perineum or unsutured tear, women who had an emergency
delivery, perineal trauma and dyspareunia. caesarean section (adjusted odds ratio [aOR] 2.41, 95% confidence
interval [95% CI] 1.4–4.0; P = 0.001), vacuum extraction (aOR
Design Prospective cohort study.
2.28, 95% CI 1.3–4.1; P = 0.005) or elective caesarean section
Setting Six maternity hospitals in Melbourne, Australia. (aOR 1.71, 95% CI 0.9–3.2; P = 0.087) had increased odds of
reporting dyspareunia at 18 months postpartum, adjusting for
Sample A total of 1507 nulliparous women recruited in the first
maternal age and other potential confounders.
and second trimesters of pregnancy.
Conclusions Obstetric intervention is associated with persisting
Method Data from baseline and postnatal questionnaires (3, 6, 12
dyspareunia. Greater recognition and increased understanding of
and 18 months) were analysed using univariable and multivariable
the roles of mode of delivery and perineal trauma in contributing
logistic regression.
to postpartum maternal morbidities, and ways to prevent
Main outcome measure Study-designed self-report measure of postpartum dyspareunia where possible, are warranted.
dyspareunia at 18 months postpartum.
Keywords Cohort studies, delivery obstetric, dyspareunia, pain,
Results In all, 1244/1507 (83%) women completed the baseline perineum, postpartum period, prospective studies, sexual intercourse.
and all four postpartum questionnaires; 1211/1237 (98%) had
Linked article This article is commented on by C Sakala, p. 680 in
resumed vaginal intercourse by 18 months postpartum, with 289/
this issue. To view this mini commentary visit http://dx.doi.org/
1211 (24%) women reporting dyspareunia. Compared with
10.1111/1471-0528.13264.
women who had a spontaneous vaginal delivery with an intact
Please cite this paper as: McDonald EA, Gartland D, Small R, Brown SJ. Dyspareunia and childbirth: a prospective cohort study. BJOG 2015;122:672–679.
maternity hospitals in Melbourne, Australia. We recruited proportions of women reporting symptoms divided by the
nulliparous women, aged over 18 years, in the first and total number of women who had resumed vaginal sex and
second trimesters of pregnancy. Women with poor Eng- had data available for the relevant period. Pain on first vag-
lish language literacy were excluded. inal sex is reported separately.
Risk factors for postpartum dyspareunia were investi-
Measures and definitions gated using univariable and multivariable logistic regres-
At recruitment, participants were asked to complete a sion. Logistic regression modelling was used to examine the
baseline questionnaire recording demographic and social association between mode of delivery and perineal trauma
characteristics, including age, country of birth and socio- (exposures of main interest) and dyspareunia at 18 months
economic status, and baseline measures of common maternal postpartum (primary outcome), taking into account poten-
morbidities, including dyspareunia before and during preg- tial confounders. Maternal age was included in modelling
nancy.1 Follow-up questionnaires were administered at 3, 6, analyses for a priori reasons. Other variables were included
12 and 18 months postpartum. Data regarding the mode of based on associations that were observed in univariable
delivery and degree of perineal trauma were collected in the analyses at 6 and/or 18 months postpartum. Data are pre-
3-month postpartum questionnaire and abstracted from sented as crude or adjusted odds ratios (ORs) with 95%
medical records for a subset of women. There was a high confidence intervals (95% CI).
degree of congruity between women’s own accounts of mode Ethical approval for the study was provided by La Trobe
of delivery and other obstetric events and data abstracted University (2002/38); Royal Children’s Hospital, Melbourne
from medical records.9,10 (27056A); Royal Women’s Hospital, Melbourne (2002/23);
Follow-up questionnaires included study-designed ques- Southern Health, Melbourne (2002-099B); and Angliss
tions regarding sexual health and dyspareunia drawing on Hospital, Melbourne (2002).
questions included in the Australian Longitudinal Women’s
Health Study11 and a study by Barrett et al.1 assessing
Results
women’s health after childbirth. Study questionnaires also
included validated measures of maternal depressive symp- Participants
toms (Edinburgh Postnatal Depression Scale)12 and inti- A total of 1507 women enrolled in the study. The mean
mate partner abuse (Composite Abuse Scale),13,14 and gestation of study participants at the time of enrolment
single item measures assessing maternal fatigue15 and infant was 15.0 weeks (range 6–24 weeks). We were unable to
feeding.16 Pretesting of the questionnaires, paying particu- determine a precise response fraction, but conservatively
lar attention to study-designed questions, was undertaken estimate that the response was between 1507/5400 (28%)
with a pilot sample of women recruited through participat- and 1507/4800 (31%). The follow-up response fractions
ing hospitals. The baseline Maternal Health Study ques- were 1431/1507 (95%), 1400/1507 (93%), 1387/1507
tionnaire is available on the study website.17 Postnatal (92%), 1326/1507 (88%) at 3, 6, 12 and 18 months post-
questionnaires can be made available by contacting the partum, respectively. In all, 1211/1239 (98%) participants
authors. were sexually active at 18 months postpartum.
Study participants were representative in relation to
Statistical analysis obstetric characteristics including mode of delivery and
Data were analysed using STATA version 13 (StataCorp., perineal trauma (see Table 1). Women born overseas in
College Station, TX, USA).18 Sample representativeness was countries where English is not the first language, and youn-
assessed by comparing data on social and obstetric charac- ger women were under-represented. Further information
teristics of participants with routinely collected perinatal regarding sociodemographic and reproductive characteris-
data for nulliparous women giving birth in the study per- tics of the sample and representativeness of study partici-
iod at the six participating hospitals, and at all public pants is available in previous papers.10,19 The 1244/1507
maternity hospitals in Victoria. (83%) women who completed all four follow-up question-
Analyses presented in the paper are restricted to women naires comprise the sample for the analyses in this paper
who completed the baseline questionnaire and all follow-up (Figure 1).
questionnaires. The proportions of women resuming vagi-
nal sex by 3, 6 and 12 months postpartum were calculated Birth outcomes
based on the proportion of women reporting resumption A total of 609/1244 (49.0%) women had a spontaneous
of sex divided by the total number of women with valid vaginal birth, two-thirds of whom (411/609, 67.5%) sus-
responses at each time point. tained a sutured tear and/or episiotomy; 134/1244 (10.8%)
The period prevalence of dyspareunia at 6 and had an operative vaginal birth assisted by vacuum extrac-
18 months postpartum was calculated based on the tion and 133/1244 (10.7%) gave birth assisted by forceps.
Table 1. Social characteristics of participants in the Maternal Health Study compared with Victorian Perinatal Data Collection Unit data
n % n % n %
The majority of these women sustained a sutured tear and/ (44.7%) women at 3 months postpartum, 496/1144
or episiotomy (124/134, 92.5% and 129/133, 97.0%, respec- (43.4%) women at 6 months postpartum, 333/1184
tively). In all, 120/1244 (9.7%) were delivered by elective (28.1%) women at 12 months postpartum and 289/1236
caesarean section and 248/1244 (19.9%) were delivered by (23.4%) women at 18 months postpartum. Of the 496
emergency caesarean section. women who reported dyspareunia at 6 months postpartum,
one-third (162/496, 32.7%) reported persisting dyspareunia
Dyspareunia following childbirth at 18 months postpartum. In all, 338/1234 (27.4%) women
By 3 months postpartum, 970/1239 (78.3%) had resumed reported dyspareunia in the year prior to the index preg-
vaginal intercourse; 1165/1239 (94.0%) by 6 months post- nancy.
partum, 1202/1239 (97.0%) by 12 months postpartum and
1211/1239 (97.7%) by 18 months postpartum. Most of the Associations with dyspareunia
women who had resumed sex by 12 months postpartum The unadjusted odds of dyspareunia at 18 months postpar-
experienced pain during first vaginal sex after childbirth tum were higher in women who gave birth by vacuum
(961/1122, 85.7%). Dyspareunia was reported by 431/964 extraction (OR 2.01, 95% CI 1.2–3.5; P = 0.013),
5 Withdrew
3 lost to follow up
16 Withdrew
6 lost to follow up
6 Withdrew
6 lost to follow up
emergency caesarean section (OR 2.04, 95% CI 1.3–3.3; other variables in the model. Elective caesarean section was
P = 0.004) or elective caesarean section (OR 1.65, 95% CI also associated with increased odds of dyspareunia at
0.9–2.9; P = 0.090) compared with women who had a 18 months postpartum, although the confidence interval
spontaneous vaginal birth with an intact perineum. Youn- suggests borderline statistical significance.
ger women (OR 1.58, 95% CI 1.0–2.5; P = 0.057), women Similar patterns of association were found between
who experienced dyspareunia before the index pregnancy dyspareunia at 6 months postpartum, mode of delivery,
(OR 2.18, 95% CI 1.6–2.9; P = 0.000), women who perineal trauma and other maternal and postnatal factors
reported intimate partner abuse from birth to 12 months (Table 3). Women who had an operative vaginal delivery
postpartum (OR 1.84, 95% CI 1.3–2.6; P = 0.001), women (with forceps or vacuum extraction) had greater than a
who reported fatigue at 18 months postpartum (OR 1.65, three-fold increase in adjusted odds of dyspareunia at
95% CI 1.2–2.3; P = 0.002) and women who reported 6 months postpartum. Emergency caesarean section and
depressive symptoms at 18 months postpartum (OR 1.97, vaginal birth with a sutured tear and/or episiotomy were
95% CI 1.3–3.0; P = 0.002) also had increased odds of associated with a two-fold increase in odds of dyspareunia
reporting dyspareunia at 18 months postpartum. after taking into account other factors in the model.
To obtain more precise estimates of the association Women who had an elective caesarean section did not
between mode of delivery and dyspareunia at 18 months have raised odds of reporting dyspareunia at 6 months
postpartum, we developed a multivariable logistic regres- postpartum. Prepregnancy dyspareunia was associated with
sion model (Table 2). A composite variable combining data a two-fold increase in odds of dyspareunia at both 6 and
on mode of delivery and perineal trauma was the exposure 18 months postpartum. Observed associations with obstet-
of main interest. Maternal age was included in the model ric intervention in multivariable models were stronger
for a priori reasons based on previous research showing than associations with postnatal factors, including mater-
that younger women are more likely to experience dyspa- nal depressive symptoms, fatigue and intimate partner
reunia.20,21 Dyspareunia before pregnancy, maternal depres- abuse.
sion, maternal fatigue and intimate partner abuse were
included because of the significant associations with dyspa-
Discussion
reunia at 6 and/or 18 months postpartum noted in univari-
able analyses. Main findings
Women who gave birth by emergency caesarean section Almost all women experience some pain during sexual
or vacuum extraction and those who reported prepregnan- intercourse following childbirth. Our findings show that
cy dyspareunia had greater than a twofold increase in the extent to which women report dyspareunia at 6 and
adjusted odds of persisting dyspareunia at 18 months post- 18 months postpartum is influenced by events during
partum compared with women who had a spontaneous labour and birth. The odds of dyspareunia at 18 months
vaginal birth with an intact perineum after adjusting for were substantially higher in women who delivered by
Table 2. Adjusted odds of dyspareunia at 18 months postpartum associated with mode of delivery, perineal trauma and other risk factors*
No Yes
n (%) n (%)
emergency caesarean section or vacuum extraction, and women reporting dyspareunia at 18 months postpartum is
somewhat higher for women who had an elective caesarean similar for women who had a spontaneous vaginal birth
section, compared with women who had a spontaneous with and without perineal damage.
vaginal birth with an intact perineum. At 6 months post- Other factors associated with dyspareunia at 18 months
partum, vaginal birth assisted with forceps was also associ- postpartum include prepregnancy dyspareunia, intimate
ated with dyspareunia, but elective caesarean section was partner abuse and maternal fatigue. These results suggest
not. These differences in the pattern of association with that clinicians should be alert to the possibility that inti-
mode of delivery may reflect limited study power for com- mate partner abuse is a potential underlying factor in per-
parisons of these subgroups. Alternatively, it is possible that sisting dyspareunia.
women recover more quickly from forceps than from vac- The finding that breastfeeding is associated with dyspa-
uum extraction, and that women having an elective caesar- reunia in the early postnatal period confirms previous
ean section that do experience postpartum dyspareunia are study findings.1 Women still breastfeeding at 6 months
slow to recover. It is noteworthy that the proportion of postpartum had a higher likelihood of experiencing
Table 3. Adjusted odds of dyspareunia at 6 months postpartum associated with mode of delivery, perineal trauma and other risk factors*
No Yes
dyspareunia at 6 months postpartum, even after adjusting on subsequent sex. Importantly for the analyses presented
for other maternal factors including mode of delivery and in this paper, the sample was representative in relation to
perineal trauma. mode of delivery.
The recruitment method did result in under-representa-
Strengths and limitations tion of younger women and women born overseas with a
Major strengths of this study are recruitment of a nullipa- non-English-speaking background. However, this is unlikely
rous pregnancy cohort in early pregnancy, frequent follow to have biased the results, as these social characteristics
up and high retention of participants to 18 months post- were unrelated to the primary outcomes reported in the
partum. All of these key features of the design of the study paper. The fact that recruitment was restricted to nullipa-
reduce the likelihood of recall bias, which is a major con- rous women, while very valuable in providing rich detail
cern in much of the previous literature. Additionally, the about the experiences of women having their first baby,
study was designed to facilitate ascertainment and differen- means that we are unable to comment on outcomes follow-
tiation of pain on first vaginal sex after childbirth and pain ing second and subsequent births.
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Women’s Health Australia: recruitment for a national longitudinal 987190/031570_pregnancy_v10_f_a_.pdf]. Accessed 17 December
cohort study. Women Health 1999;28:23–40. 2014.
12 Cox J. Perinatal Mental Health: A Guide to the Edinburgh Postnatal 18 StataCorp. Stata Statistical Software: Release 13. College Station,
Depression Scale (EPDS). London: Gaskell, 2003. TX: StataCorp LP, 2013.
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14 Hegarty KL, Sheehan M, Schonfeld C. A multidimensional definition 20 Richters J, Grulich AE, de Visser RO, Smith AMA, Rissel C. Sex in
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15 Woolhouse H, Gartland D, Perlen S, Donath S, Brown SJ. Physical people aged 16–59 years which had a broad focus across many
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