Chapter 9: The Cell Cycle and Cellular Reproduction Worksheet

Name ______________________________________Date______________________________

1. The _____________ _____________ is a repeating sequence of growth, replication of DNA and cell
division.

2. Most of the cell cycle is spent in _____________.

3. Interpahse includes three stages: ________________, _____________, and ___________.

4. Tell what happens in each stage.

a. G1 _____________________________________________________

b. S ______________________________________________________

c. G2______________________________________________________

5. The two major stages of the cell cycle:

a. _________________________

b. _________________________

6. ___________ and ___________ cells do not complete the cell cycle and remain in G0 stage.

8. Mitosis also known as ___________ is nuclear division, ______________ is division of the cytoplasm.

9. When division of the cytoplasm is complete what is produced? __________________

10. A ____________ is an agent that influences the activities of a cell.

11. ________________ is programmed cell death and involves a sequence of cellular events.

12. List some ways in which cell death is a normal and necessary part of development.

_________________________________________

_________________________________________

_________________________________________
13. List the three critical checkpoint of mitosis.

_________________________________

_________________________________

_________________________________

14. How many chromosomes do humans have? _________________

15. The _______________ number includes two sets of chromosomes of each type. It is found in all
non-sex cells of an organism’s body (with a few exceptions).

16. The _____________ number contains one of each kind of chromosome.

17. In the life cycle of many animals, only the ____________ and ___________ cells have the haploid
number.

18. Mitosis is divided into five phases: prophase, prometaphase, metaphase, anaphase and telophase.
In the chart below describe what happens in each stage.

Prophase

Prometaphase

Metaphase

Anaphase

Telephase

19. State the functions of Mitosis.

____________________________________________________

____________________________________________________

____________________________________________________

____________________________________________________
20. There are two types of cloning. List them below.

____________________________________________

____________________________________________

21. __________________ is a cellular growth disorder that occurs when cell divide uncontrollably.

22. Most begin as abnormal growth that is ___________________.

23. When additional mutations occur, the growth becomes ________________ and possesses the
ability to spread.

24. List the characteristics of cancer cells.

____________________________________________________

____________________________________________________

____________________________________________________

____________________________________________________

_____________________________________________________

25. Many types of cancer cells undergo _____________________, in which new tumors form which are
distant from the primary tumor.

26. ______________________ the formation of new blood vessels, is required to bring nutrients and
oxygen to the tumor.

27. _______________________ code for proteins that stimulate the cell cycle and prevent apoptosis.

28. _______________________________________ code for proteins that inhibit the cell cycle and
promote apoptosis.

29. _________________ of either of these genes can cause cancer.

30. Prot-oncogenes can undergo mutation to become ____________________ cancer –causing genes.

31. Researchers have identified about a half dozen tumor-suppressor genes. The __________ tumor-
suppresser gene prevents retinoblastoma, a cancer of the ______________ and has been found to
malfunction in cancers of the _____________, _____________ , ________________ and small-cell
____________ ________________.
32. The _______ tumor –suppressor gene is more frequently mutated in human cancer than any other
known gene.

Matching

_____33. Centromere a. type of cell division in which daughter cells receive

_____34. Chromatin the exact chromosome and genetic makeup of the
_____ 35. Cytokinesis parent cell.
_____36. Interphase b. Division of the cytoplasm following mitosis and
_____37. Mitosis meiosis
_____ 38. Oncogene c. Stages of the cell cycle (G1, S, G2) during which
_____39. Prophase growth and DNA synthesis occur when the nucleus
_____40. Spindle is not actively dividing.
_____41.Telomere d. Tangled mass of thin threads consisting of DNA and
associated proteins observed within a nucleus that is
not dividing.
e. Microtubule structure that brings about
chromosomal movement during nuclear division.
f. Mitosis phase during which chromatin condenses so
that chromosomes appear.
g. Constricted region of a chromosome where sister
chromatids are joined and where the chromosome
attaches to a spindle fiber.
h. Cancer -causing gene.
i. Tip of the end of a chromosome that shortens with
each cell division.