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3 Ischemic Heart Disease - Google X 43 Free Online OCR convert PDF
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3. Pathobiology of ischemic heart disease

eBuku tidak tersedia Hypoxia refers to the physiological or pathological state in which oxygen supply is reduced
despite adequate perfusion of the tissue. Anoxia is the absence of oxygen from the tissue,
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- despite being adequately perfused. These are clearly distinguishable from ischemia where
Amazon.com oxygen supply is restricted as a direct result of suboptimal tissue perfusion. Ischemic tissue
BukuKita.com also accumulates toxic metabolites due to the inadequate removal through the capillary and
Gramedia venous blood systems.

Cari di perpustakaan The atherosclerotic process responsible for restriction of blood flow in the coronary arteries
Semua penjual s is a multifactorial process and is initiated by damage to the endothelium. Cholesterol rich low
density lipoprotein (LDL) particles enter the intimal layer via the LDL receptor protein (Brown
and Goldstein 1979), a mosaic cell surface protein that recognizes apolipoprotein I3100
***** embedded in the LDL particle. It also recognizes apolipoprotein E found in chylomicrons and
Resensi very low density lipoprotein remnants, or intermediate density lipoprotein. Macrophage cells
Tulis resensi accumulate oxidized lipid independently of the LDL receptor by endocytosis. This results in
formation of juvenile raised fatty streaks within the endothelium. The macrophage release
their lipid content and cytokines into the intima. Cytokines stimulate intimal thickening by
Ischemic Heart Disease
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