INDICATION &

MEDICATION MECHANISM OF ACTION ADVERSE EFFECT NURSING RESPONSIBILITIES

CONTRAINDICATION

GENERIC NAME: ACTION: INDICATIONS: CNS: asthenia, headache,  Monitor fasting glucose level
dizziness. periodically to determine
Glimepiride Lowers glucose level by  Adjunct to diet and therapeutic response. Also
stimulating release of insulin exercise to lower glucose EENT: changes in monitor HbA1c level, usually
BRAND NAME: from functioning pancreatic level in patients with type accommodation. every 3 to 6 months, to
beta cells, and may lead to 2 diabetes. precisely assess long term
Amaryl increased sensitivity of GI: Nausea glycemic control.
peripheral tissues to insulin. CONTRAINDICATIONS:
THERAPEUTIC CLASS: Metabolic: hypoglycemia,  Tell patient to take drug with
 Patient hypersensitive to dilutional hyponatremia. first meal of the day.
Antidiabetics drug and those with
diabetic ketoacidosis, Respiratory: flulike symptoms.  Advise patient to avoid
PHARMACOLOGIC which should be treated alcohol, which lowers glucose
CLASS: with insulin. level.

Sulfonylureas  Contraindicated in patient  Explain to patient and family

with sulfonamide allergy. how and when to monitor
glucose level, and teach
 Use cautiously with drugs recognition of and intervention
that can cause for signs and symptoms of
hypoglycemia. high and low glucose level.

 Use cautiously in  Advise patient to consult

debilitated or prescriber before taking OTC
malnourished patients products or supplements.
and in those with adrenal,
pituitary, or renal  Make sure that patient
insufficiency; these understands that therapy
patients are more relieves symptoms but doesn’t
susceptible to the cure the disease. Also
hypoglycemic action of understand potential risk and
glucose-lowering drug. advantages of taking drug.


Yessamin Paith M. Roderos DRUG STUDY BSN-2

Yessamin Paith M. Roderos DRUG STUDY BSN-2