Introduction Method 1 – Direct Handling of When determining how to transfer liquid waste wit- Liquid Waste Application hin an analyzer, design engineers must examine many Liquid pumps can directly handle NOTE factors. Though several methods will work, only one waste fluids, and either transfer provides optimized system performance and lifetime. them to a collection tank or pump them straight to waste/drain. (see OEM Laboratory and clinical diagnostic applications encom- flow diagram below) The advanta- pass a wide spectrum of processes, including probe ges to this de-centralized approach are: simplicity of washing, sample well or couvette emptying and was- pump control, small pump size, lower pump cost, and hing, slide staining, rinsing, reagent washing, and gene- possibly fewer system components. Additionally, the ral draining. Many of these processes generate liquids system is more easily re-configured if flow require- that must be pumped to waste. These liquids range from ments change. Frequently, the same pump model spe- simple DI water to bleach concentrations, to remainders cified for the probe wash function is also used here for from tests that include sticky proteins, magnetic beads a better economy of scale, although high pressure and particles, and chemical reaction leftovers. Additional- pumps may be the best choice for the washing ly, molecular diagnostics involves cell lysing and amplifi- function. cation, processes that can include elevated temperatures and aggressive chemicals. All of these differing proces- A designer should be aware that the pump will be ses and media add complexity to pump selection decisi- pressurizing liquid that will probably contain biological ons. System design engineers are encouraged to talk waste, so extra caution should be exercised to prevent with KNF Applications Engineers to be certain the best clogging or leakage. Lines should be smooth, as short pump is selected for the intended function. as possible, and of the widest diameter possible. Pres- sure limiting devices should be considered (KNF can There are two main methods for removing liquid waste include these in the pump head or as a separate com- from an analyzer: Direct Handling, and Waste Collection ponent). Pumps are more prone to clogging if shards of followed by Evacuation. glass or other large debris are present in the fluid. Filtering upstream from the pump may be necessary to the pump used in this application must develop a assure no particles are present (typically >100 microns). vacuum deeper than the gas vacuum pump used for As the media is a combination of liquid and air, the de- vacuum over liquid collection (typically up to 27 “Hg). A signer may be tempted to consider a gas handling mo- liquid pump is required for this function, and it may del. This should usually be avoided because the even be the same pump used to move the liquid to incompressible properties of liquids require a pump waste in either of the applications described above. The designed specifically for liquid service. The direct hand- advantage to this type of pumping solution is that the ling of liquid waste method requires proper sizing of instrument is able to continue processing fluids during the pump(s) and timing of valves to ensure highest-case the evacuation process, thus increasing sample flow rates can be handled. One advantage to this me- throughput. The diaphragm pump’s vacuum generating thod is increased tolerance to system modifications. ability remains stable over time, unlike that of a peristal- tic, piston, gear, or rotary. It should also be more reliable Method 2 – Waste Collection, then Evacuation and consistent than house vacuum, especially if the Vacuum Over Liquid Collection – Another popular vacuum is consumed on a continuous basis. method involves a centralized diaphragm pump (nor- mally gas) that develops and maintains a vacuum in a Tank Evacuation, Pressure over Liquid – An alternati- sealed reservoir, which is connected via solenoid valves ve to direct handling, this solution has the advantage or a manifold to the various liquid lines. that the pump is not in contact with the collected waste and debris. However pressure over liquid is still less Thanks to recent advances in diaphragm pump techno- popular because of two possible problems: (1) clogging logy, this pump type is preferred over traditional re- downstream of the tank may allow medical waste to ciprocating piston, scroll, or rotary pumps. Diaphragm escape outside the containment area, and (2) the pumps have earned this distinction owing to their ability vacuum in the tank must be broken, leading to reduced to handle the inevitable humid vapors and even liquids throughput. on occasion. Other pump types may be damaged from this mixed media, however a diaphragm pump can KNF Diaphragm Pumps for Liquid Waste Handling handle it easily – usually requiring just a simple air purge ■■ Many wetted materials from which to choose to resume normal operation if a gas pump is selected, ■■ Many motor options, including long-life, brushless and probably no purge at all if a liquid pump is used. DC with logic speed-control ■■ Liquid flow rates to 6 L/min ■■ Self-priming liquid pumps Liquid pumps are usually the pump of choice if the ■■ Air/Gas flow rates to >150 L/min mixed media flow rates are small (< 5 L/min combined ■■ Custom OEM projects encouraged liquid and gas) while gas pumps are favored for higher flow rates up to 150 L/min or more. Vacuum may be maintained in the tank via speed-controlling the pump to optimize system noise and lifetime, or the pump may be cycled on and off as required. One benefit of the vacuum over liquid method is it allows flexibility in dealing with varying amounts of generated waste. Multiple lines may be handled by a relatively small pump if the vacuum needs can be timed properly.
Tank Evacuation, Direct Handling – Once the waste collection tank is full—as determined by a sensor or on a quasi-continuous basis for tank size reduction—it must be evacuated to waste/drain. Again, diaphragm Rev:Jan 2017
liquid pumps excel in this application. Direct handling
with a diaphragm pump is probably the most popular way to evacuate the liquid waste since these pumps are able to withstand the myriad of accumulated chemi- cals. In order to generate flow in the proper direction, A selection of KNF pumps for Liquid Waste Handling applications.