Beruflich Dokumente
Kultur Dokumente
Group
Hina zamir (04)
Mahnoor khan (02)
Rameen Nadeem (25)
Syeda iqra Hussain
(?05)
Maleeha Inayat (06)
Overview
• Genomics overview
• Goal of genomics
• Types of genomics overview
• Structural genomics
• Functional genomics
• Mutational genomics
• Comparative genomics
Genomics overview
Genome: entirety
of genetic material
coined by Winklen
1920
Genomics: field of
study where entire
genome is studied
Coined by Thomas
Rhodrick
als of genomics
Compile the genomic sequences of organisms
Search out the location of the genes for
analyzing spatial relationships and annotate the
gene set in a genome
Learn the function of genes and their influence
Establish how gene expression profiles of a
cell vary under different conditions.
Compare gene and protein profiles among
different organisms to learn about evalutionary
relationships.
Structural Functional genomics:
genomics: • Aims to collect and use
• Aims to determine data from sequencing
structure of every for decribing gene and
protein encoded by protein functions
the genome.
• Identify novel • functions of genes and
protein folds and 3- non-gene sequences in
D structures for genomes
better
understanding the • Gena and protein
functions of interactions
proteins. • Genotype- phenotypes
Comparative Genomics Mutational Genomics:
• Aims to compare
• The study of genome in
genomic features terms of mutations that
between different species occur in an individual’s
• e,.g. for better DNA or genome
understanding the
evaloutionary • One of the aspect of
relationships.
functional genomics
• to determine the function
of each genome E.g • Also referred as gene
studying genes in model function determination
organisms
• Yeast and human • Aim to determine
function of gene
• Or anonymous
sequence
Structural genomics
Definition