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1.

What volume of 1M MgCl2 stock solution will be needed to prepare 50 ml of 25 mM


solution?
a. 1 ml
b. 1.25 ml
c. 2 ml
d. 4 ml

2. A 12 hour standard clock is started at noon, by 10 minutes past 5:00 PM, the hour hand has
turned through
a. 155°
b. 145°
c. 152°
d. 140°

3. In a 500 meter race the ratio of the speed of contestant A and B is 3:4. If contestant A has a
head start of 140 meter, then A will win the race by
a. 60 m
b. 20 m
c. 40 m
d. 10 m

4. Present age of Kiran and Amir are in the ratio of 5:4 respectively. Three years from now the
ratio of their ages will be 11:9. The present age of Amir is
a. 28 years
b. 27 years
c. 26 years
d. 24 years

5. What is the probability of getting a number less that 4 when a dice is rolled?
a. ¼
b. 1/3
c. ½
d. 1/6

6. A carbonated drink, pH 4, is how many times more acidic than distilled water (pH 7)
(a) 3
(b) 4
(c) 4000
(d) 1000

7. A polypeptide of 38.5 kDa will be coded by an ORF of the size


(a) 0.21 kb
(b) 2.1 kb
(c) 1.05 kb
(d) 1.5 kb

8. Which of the following reactions produces most ATP molecules during aerobic metabolism?
(a) Glucose to Pyruvate
(b) Succinate to Fumarate
(c) Acetyl ~CoA to CO2 + H2O
(d) Phosphoenolpyruvate to Pyruvate

9. The oxidation state of iron in methaemoglobin is:


(a) +3
(b) +2
(c) +4
(d) 0
10. The correct set of the biological essential elements is:
(a) Fe, Mo, Cu, Zn
(b) Fe, Mo, Co, Ru
(c) Cu, Mn, Zn, Ag
(d) Fe, Ru, Zn, Mg

11. “Dolly” was genetically similar to


(a) The mother from which enucleated egg cell was taken
(b) The mother from which nuclear DNA of udder cell was taken
(c) The surrogate mother
(d) Both surrogate mother and nuclear donor mother

12. DNA sequence is 5’TAG 3’. What shall be the sequence in anticodon of tRNA?
a) UAG
b) ATC
c) ATG
d) UAC

13. Which one of the following is associated with an ABC transporter? (cell bio)
a) multidrug resistance protein
b) acetylcholine receptor
c) bacteriorhodopsin
d) ATP synthase

14. Who created the first synthetic bacterial genome?


a) Craig Venter & team
b) Francis Collin & team
c) James Watson & team
d) Rosalind Franklin & team

15. Paris Agreement 2015 within the “United Nations Framework Convention on Climate Change” aims
at
a) holding the rise in sea level
b) holding the increase in the global average temperature to well below 2 °C above pre-
industrial levels
c) controlling the release of green house gases by the developed countries
d) helping the developing countries to control their green house gas emission

16. Of the four techniques (i) mass spectrometry, (ii) NMR, (iii) X-ray crystallography and (iv)
Circular dichroism, the techniques used for molecular structure determination at atomic
resolution are:
(a) (i), (ii), (iii) and (iv)
(b) (ii) and (iii)
(c) (i), (ii) and (iii)
(d) (i) and (iii)

17. Root mean square deviation between two conformations of a protein cannot be:
(a) less than zero
(b) positive
(c) nearly zero
(d) greater than 3.0 Angstroms

18. If the value of CosA is 1 then what is the value of Sin 3A


a. 0
b. ½
c. 3/2
d. 1

19. Find the area of the square circumscribed by a circle of 20 cm diameter.


a. 100 cm2
b. 200 cm2
c. 400 cm2
d. 800 cm2

20. Very high microbial cell density can be obtained in a fermenter by


a. Variable volume fed batch culturing
b. Fixed volume fed batch culturing
c. Continuous culturing
d. Batch culturing

21. Which of the following is NOT a probiotic


a. Lactobacillus casei
b. Saccharomyces cerevisiae
c. Bifidobacterium
d. Acinetobacter baumannii
22. Consider two protein antigens, X and Y. Antigen X has a molecular weight of
150,000 and is made up of a single repeating epitope. Antigen Y has a molecular
weight of 100,0000 and is made up of 10 different types of epitopes. Which
antigen is more immunogenic?
a. antigen X
b. antigen Y
c. of equal immunogenicity
d. can’t be determined from given data

23. The protection against small pox virus infection afforded by prior infection with
cow pox virus represents
a. antigenic specificity
b. antigenic cross reactivity
c. innate immunity
d. passive protection

24. In the mitochondrial electron transport chain, the mobile electron carrier is:
(e) Cytochrome P450
(f) Coenzyme Q
(g) Rotenone
(h) NADH

25. An example of posttranslational modification of protein is its:


a. inhibition due to ATP-binding
b. coordination with Zn++
c. activation by a protein kinase
d. secretion through the Golgi body

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