Beruflich Dokumente
Kultur Dokumente
Iulian Stratan
Recommendation 22 Recommendation 23
Once the presence of infection is documented No use for other immuno-modulating therapies
or highly suspected and patients with SAP meet the targeting inflammatory mediators in SAP as anti-
definition of severe sepsis that management accord- TNFá therapy and lexipafant. (Grad A, level 1 evi-
ing to current sepsis guidelines be initiated. These dence for lexipafant; Grad D level 5 evidence for all
therapy include the use of rh-ACP (grade A level 1b) other therapy)