ANTIBIOTIC

Disease Antibiotic
External otitis
1. Acute Ofloxacin ED 5-10 gtt bid
2. Chronic ED polymyxin + neomycin + steroid QID
3. Fungal Fluco 200mg 1 dose  100 mg 3-5 days
Otitis media
1. Acute No AB before: Amox HD (90mg/kg/day div q12h or q8h)
AB before: Amox HD/AM-CL (<2th 10 days, >2th 5-7 days)
2. Clinical failure after 3 No AB before: AM-CL HD / IM ceftri (50mg/kg for 3 days
days AB before: IM ceftri / Clindamycin (20-30mg/kg/day div qid)
3. Adult See sinusitis
Mastoiditis Ceftri 2gm IV once daily
Blepharitis Baby shampoo + warm compress q24h. artif tear if assoc dry eyes
Hordeolum
1. External Hot packs only. Will drain spontaneously
2. Internal TMP-SMX-DS (4mg/kg q12h/tabs II bid po)
Conjunctivitis
1. Newborn Ceftri (25-50mg/kg, not exceed 125mg)
2. Viral No treatment/artif tear
3. Inclusion conj Azithro 1gr once/doxy 100mg bid 7 days)
(chlamydia)
4. Trachoma Azithro 1gr once/doxy 100mg bid 7 days)
5. Bacterial Cip/Besi/Levo/Moxi 1-2 gtt q2h while awake 1st 2 days, then q4-8h
up to 7 days
6. Gonococcal Ceftri (25-50mg/kg, not exceed 125mg) ped // 1gr one dose adult
Keratitis
1. Viral Trifluridine opht sol 1 gtt q2h until re-epithelialized  1 gtt q4h up
to 5 days
2. Varicella Valacyclovir 1 gr po tid x 10 days/acyclovir 5x800mg x 10 days

3. Bacterial Cip 1-2 gtt hourly while awake 1-3 hr, then taper

4. Fungal Natamycin 5% 1 gtt q2h for several days, the q3-4h for several days
Canaliculitis Irigate granules
Child: AM-CL
Orbital cellulitis Ceftri 2gr IV q24h + metro 1gr IV q12h
Diabetic foot
1. Mild infection AM-CL(875/125 mg bid)/Doxy (100mg bid)/TMP-SMX-DS (1-2 tabs
bid)/Clinda (300-450mg tid)
2. Moderate Oral : as above
infection/osteomyelitis Parenteral
3. Extensive Cip 400mg IV q12h/levo 750mg IV q24h + metro 1grm IV loading
dose then 0.5 gr q6h or 1gr q12h
Gallbladder
Cholecystitis, cholangitis, Parenteral
biliary sepsis or common duct
obstruction
Gastrointestinal
1. Mild diarrhea
2. Moderate diarrhea
3. Severe diarrhea Cip (500mg bid) or levo (500mg q24h) 3-5 days
TMP-SMX-DS po bid 3-5 days
4. Aeromonas CIP 750mg bid 3 days

5. Amebiasis Paromomycin 25-30mg/kg/day in 3 div dose x 7 days + metro 500-

750mg tid 7-10 days
6. Campilobacter jejuni Azithro 500mg q24h 3 days or azith 1gr po one dose or cip 500 bid

7. C. difficile Metro 500mg po tid or 250 mg qid x 10-14 days

8. EHEC Azithro 500mg IV/po once daily x 3days

9. Salmonella Cip 500 bid/ levo 500 q24h x 7-10 days / azith 500 mg po once daily
x 7days
10. Shigella Cip 750mg po bid x 3 days / azithro 500mg po once daily x 3 days

11. Vibrio cholerae Doxy 300mg po single dose / azithro 1 gr single dose / tetra 500mg
qid x 3 days / erithro 500mg qid x 3 days
12. Travellers diarrhea Cip 750mg po bid 1-3 days/ levo 500 q24h 1-3days / azithro 1 gr po
single dose/ azithro 500mg q24h 3 days
Peptic ulcer PPI + amox 1000mg bid + metro 500mg bid + clari 500mg bid x 14
days
Diverticulitis, perirectal Outpatient – mild infection, drained perirectal abscess
abscess, peritonitis TMP-SMX-DS bid or CIP 750mg bid / levo 750 mg q24h PLUS metro
500mg q6h. all x 7 -10 days
Or AM-CL 1000mg/62,5 2 tab po bid x 7-10 days
Chancroid Ceftri 250 mg IM single dose / Azithro 1 gr po single dose / cip 500
mg bid po x 3 days / erithro 500mg tid x 7 days
Non GO urethritis, cervicitis Doxy 100 bid x 7 days / azithro 1 gr single dose (safe utk pregnant) /
levo 500 q24h 7 days / erithro 500 tid 7 days
Recurrent urethritis Metro 2gr po + azithro 1 gr po single dose
Proctitis Doxy 100 bid 7 days
Gonorrhea
1. Conjunctivitis Ceftri 1gr IM/IV single dose + Azith 1 gr PO x 1
2. DGI Ceftri 1gr IM/IV single dose + Azith 1 gr PO x 1
3. Endocarditis Ceftri 1-2gr IM/IV q12-24h x 4 wks + Azith 1 gr PO x 1
4. Pharyngitis Ceftri 250 mg IM single dose + Azithro 1 gr po single dose
5. Urethritis, cervicitis, Ceftri 250 mg IM single dose + Azithro 1 gr po single dose
proctitis

Granuloma inguinale Azith 1 gr po qwk x 3wk

LVG Doxy 100 bid x 21 days
Syphilis Benzathin penisilin G 2,4 mio units IM SD + azith 2 gr po SD
PID Ceftri 250mg IM 1x + + metro 500mg po bid x 14 days + Doxy 100mg
po bid x 14 days
Vaginitis
1. Candidiasis Fluco 150mg po SD or Itra 200 mg po bid 1 day or intravaginal azole
1 dose 7-14 days
2. Trichomoniasis Metro 2 gr po SD
3. BV Metro 500mg po bid x 7 days or Metro vaginal gel 1/day x 5 days or
clinda vaginal cream 5gr intravag at bedtime x 7 days
Balanitis Metro 2 gr po SD or fluco 150 mg po SD or Itra 200mg po bid 1 day
Epidydimo-orchitis <35 years Ceftri 250mg IM 1x + Doxy 100mg po bid x 10 days
>35 years Leco 500-750 po once daily
Prostatitis – acute Ceftri 250mg IM 1x + Doxy 100mg po bid x 10 days
uncomplicated
Chronic bacterial CIP 500 po bid x 4-6 weeks or Levo 750 mg po q24h x 4 weeks / TMP
SMX- DS 1 tab po bid x 1-3mos
KIDNEY AND BLADDER
Uncomplicated (Women)
1. Cystitis Nitrofurantoin 100mg bid x 5days / TMp-SMX-DS 1 tab bid x 3days /
fosfomycin 3gr po x 1 dose / Cipro 250mg bid
2. Pyelonephritis Outpatient : ceftri 1 gr IV then cipro 500mg bid / levo 750 once daily
x 7 days
Pregnancy
1. Asymptomatic Nitrofurantoin (not in first trimester) 100mg bid x 5-7days/ amox-
bacteriuria & cystitis clav 500mg po q8h x 3-7 days / TMP SMX DS (not in 1st trimester) 1
tab po bid x 3days
2. Acute pyelonephritis ceftri 1 gr IV
Recurrent UTIs in women TMP-SMX-SS 100 mg / cephalexin 250mg / cip 125 mg po once daily
Uncomplicated (Man)
1. Cystitis TMP-SMX-DS 1 tab bid x 7-14 days / cipro 500mg bid / levo 750
2. Pyelonephritis once daily x 7-14 days
Cip 400mg IV q12h / levo 750mg IV once daily
Acute Complicated UTI (Men & levo 750mg IV once daily / ceftri 1 gr IV
Women)

Bronchitis
Acute on COPD
Bronchiectasis
Pneumonia
1. Neonatal
2. Age 1-3 months
3. Infant and children,
age >3 months – 18
year
4. Adult