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I. OBJECTIVE(S) At the end of the lesson, at least 75% of the students with 75 proficiency should be
able to compare the structures of DNA and RNA based on the ff.:
a. Number of strands
b. Location in the cell
c. Type of sugar
d. Nitrogenous base pair
II. LESSON A. UNIT 3 : Living Things and their Environment
Module 2 : Heredity: Inheritance and Variation
Topic: DNA and RNA Structures

B. Reference/s: Science Learner’s Material for Grade 10 pp. 263-268

C. Materials: pictures of DNA and RNA

A. ENGAGE 1. Students will be given paper strips and they will be asked to write
words/phrases that they can relate to DNA.
2. A representative from each group will explain their answers.
B. EXPLORE 1. Students will do Activity 1 Getting to Know the DNA and RNA Structure.
2. Remind learners to answer the guide questions.
3. Based from their output, they will compare the structures of the two in
terms of the ff;
a. Number of strands
b. Location in the cell
c. Type of sugar
d. Nitrogenous base pair
C. EXPLAIN 1. Answers to the ff. guide questions will be solicited from the students.

Answer to comparison table.

Basis of Comparison DNA RNA
1. Number of strand 2 1

nucleus cytoplasm
2. Location in the cell

3. Type of sugar deoxyribose ribose

A, T, C, G A, U, C, G
4. Nitrogenous bases

Guide Questions:
Q1. What are the components of the DNA and RNA molecule?
(The DNA and RNA are made up of three components: namely:
a. sugar
b. phosphate group, and
c. nitrogenous base )
Q2. What is the structural difference between DNA and RNA? (DNA and RNA are
different in the following:
a. DNA is double stranded while RNA is single-stranded.
b. The sugar in DNA is deoxyribose while that in RNA is ribose.
c. The nitrogen bases in DNA are adenine (A), guanine (G), thymine (T) and
cytosine (C). In RNA are adenine, guanine, cytosine and uracil. )
Q3. What nitrogenous base is found in RNA but not in DNA? (Uracil)
• A DNA is a double helix molecule composed of complementary
strands of deoxyribonucleotides units. The complementary base
pairs of the DNA are held by hydrogen bonds.
• RNA is single stranded.
• Examples of RNA types include: mRNA, rRNA and tRNA.
• In DNA, adenine always bonds with thymine, and cytosine bonds
with guanine. In RNA, adenine bonds with uracil, and cytosine
bonds with guanine
2 ELABORATE Building a house usually requires a blueprint, or a plan of the structure
of the house to determine how it would look like after construction. Organisms have
blueprints which contain information that will determine their physical and
chemical characteristics. This blueprint is DNA.
3 EVALUATE Make a Venn diagram showing the similarities between rna and dna.

IV. ASSIGNMENT Construct a model of a dna molecule using recyclable materials.


No. of Learners with Mastery Level
No. of Learners Needing Reinforcement