Republic of the Philippines

PALAWAN STATE UNIVERSITY

COLLEGE OF NURSING AND HEALTH SCIENCES
Puerto Princesa City

PHARMACOLOGICAL MANAGEMENT
DRUG STUDY

Date Ordered: February 3, 2020

Name of Drug Dosage Mechanism of Action Adverse Reaction Indication Contraindication Nursing
Reaction/Responsibility
Generic Name: -1 Litre TC -Lactated Ringer's and -Reactions which may occur -This solution is -This solution is -If an adverse reaction does
D5LR + 10 "U" for 8 hours 5% Dextrose because of the solution or the indicated for use in contraindicated where the occur, discontinue the
OXY - Injection, USP has technique of administration adults and pediatric administration of sodium, infusion, evaluate the
Intravenous value as a source of patients as a source
include febrile response, potassium, calcium, chloride patient, institute appropriate
water, electrolytes, of electrolytes,
Brand Name:
and calories. It is infection at the site of or lactate could be clinically therapeutic countermeasures
Lactated Adult: injection, venous thrombosis calories and water detrimental. and save the remainder of
capable of
Ringer’s As an or phlebitis extending from for hydration. the fluid for examination if
inducing diuresis depe
Solution alkaliniser deemed necessary.
nding on the clinical the site of injection, -Solutions containing
agent; condition of the extravasation and dextrose may be
Replaceme patient. hypervolemia. contraindicated in patients
nt of fluid
and with known allergy to corn
-Lactated Ringer's and
electrolyte. 5% Dextrose -Too rapid infusion of or corn products.
Dose Injection, USP hypertonic solutions may
depends on produces a metabolic cause local pain and venous -Lactate administration is
age, weight alkalinizing effect. irritation. contraindicated in severe
and clinical Lactate ions are metabolic acidosis or
state of the metabolized -Hypernatremia may be alkalosis, and in severe liver
patient. To ultimately to carbon associated with edema and disease or anoxic states
be given by dioxide and water, exacerbation of congestive which affect lactate
IV infusion. which requires the heart failure due to the metabolism.
consumption
retention of water, resulting
of hydrogen cautions.
in an expanded extracellular -Solutions containing
fluid volume. dextrose may be
contraindicated in patients
-Reactions reported with the with hypersensitivity to corn
use of potassium-containing products.
solutions include nausea,
vomiting, abdominal pain
and diarrhea. result in
disruption of neuromuscular

-Hypervolemia

-Other infusion site

reactions: infection at the site
of injection, phlebitis,
extravasation, infusion site
inflammation, infusion site
swelling, infusion site rash,
infusion site pain, infusion
site burning.
 Republic of the Philippines
PALAWAN STATE UNIVERSITY
COLLEGE OF NURSING AND HEALTH SCIENCES
Puerto Princesa City

Date Ordered: February 2, 2020

Name of Drug Dosage Mechanism of Action Adverse Reaction Indication Contraindication Nursing
Reaction/Responsibility
Generic Name: Adults: Amlodipine is an CNS: headache, -Hypertension -Contraindicated in patients -Monitor patient carefully,
AMLODIPINE Oral; 5mg; angioselective calcium somnolence, fatigue, -Chronic stable angina, hypersensitive to drug. Some patients, especially
OD channel blocker and dizziness. vasospastic angina -Use cautiously in patients those with severe
Brand Name: inhibits the movement (Prinzmetal or variant receiving other peripheral obstructive coronary artery
CV: edema, flushing, angina); to reduce risk of
Norvasc of calcium ions into vasodilators, especially disease, have developed
palpitations. hospitalization because of
vascular smooth those with severe aortic increased frequency,
muscle cells and angina; to reduce risk of
GI: nausea, stenosis or hypertrophic duration, or severity of
coronary revascularization
cardiac muscle cells abdominal pain. cardiomyopathy with
procedure in patients with angina or acute MI after
which inhibits the outflow tract obstruction,
Respiratory: recently documented CAD initiation of calcium
contraction of cardiac by angiography and
pulmonary edema, and in patient with HF with channel blocker therapy or
muscle and vascular without HF or with LVEF
dyspnea reduced left ventricular at time of dosage increase.
smooth muscle cells. less than 40%.
ejection fraction. Because -Monitor BP frequently
Skin: pruritus, rash
drug is metabolized by the during initiation of
liver, use cautiously and in therapy. Because drug-
-Dizziness,
lightheadedness, reduced dosage in patients induced vasodilation has a
swelling ankles/feet, with severe hepatic disease. gradual onset, acute
or flushing may occur. hypotension is rare.
-Notify prescriber if signs
of heart failure occur, such
as swelling of hands, feet
or shortness of breath.
-Abrupt withdrawal of
drug may increase
frequency and duration of
chest pain. Taper dose
gradually under medical
supervision.