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GROUP VI :
ALCOSER ARCILA ALONSO
DE LA CRUZ RUIZ LENIN
MENDOZA MEGO BORIS
LUMBRE YUPTON CESAR
QUEVEDO MORI ARTURO
REGALADO ROCHA WILINTON
CYCLE : 2010-I
Lambayeque, Perú
September 2010
CURRENT MEDICINE
Among the most sophisticated diagnostic elements are the modern techniques
of reconstruction of three-dimensional models of the body (traditional CT,
ultrasound, computed tomography and magnetic resonance imaging), and
direct views from inside the body (arthroscopy, endoscopic surgery, cardiac
surgery remote control, etc.).. Examination by analytical chemistry and image
can now know every corner and reactions of the human body.
Advances in surgery are also spectacular. The use of the microscope, the laser
beam as a dissector, transplantation techniques, which have enabled
thousands of lives saved due to the introduction of entire organs (heart, kidney,
liver ...) in hospice-techniques endoscopic surgery, the many interventions
guided fine on small areas of the brain, and even the current trials of robotic
surgery and controlled by computer without almost anything involving the
intervention of human hands, added all at best sutures, hemostasis systems ,
cutting and dissection, have created a very satisfactory picture surgery.
One of the most significant surgical fields is the reference to the heart and great
vessels. The valve expansion techniques (intravenous today), recanalization of
coronary and other open heart achievements, unimaginable until recently, have
made possible the continuation of the lives of many patients.
But medicine still has to face many challenges, among which are cancer, the
treatment of many mental illnesses like Parkinson's and Alzheimer's disease,
and many infectious diseases such as hepatitis and AIDS (Acquired
Immunodeficiency Syndrome).
Although science has made major achievements in combating infectious
diseases, there are others for which there is no known effective method of
combat.
In the case of AIDS, for example, although drug therapy has increasingly better
results, has long been trying to find a vaccine to curb this scourge of our times.
The hepatitis B virus (HBV), in addition to producing liver disease, causes a
common form of cancer, and is the most important human carcinogen, after
snuff. In this sense, the progress of molecular biology of HBV has found
interesting medical applications, among which are prevention of infection
through vaccination. They have high hopes for new vaccines created through
genetic engineering, for the eradication of such diseases.
Cancer, for its part, is very different methods depending on the type, but today
is still looking for a system of immunotherapy, ie a treatment to increase the
potential innate immune system, which is the main natural defense the body
against viruses and other foreign invaders, including organ transplantation, to
eliminate cancer cells. And in any case, immunotherapy is a good complement
to existing treatments.
Medical developments promise better health in the future, through the use of
new therapies, genetic manipulation, construction of artificial organs, the use of
drug design and implementation of other ingenious techniques to restore organ
function. Likewise, counter many more infectious agents. However, all this
knowledge must be applied to enable a better quality of life, and we must take
into account ethical issues that every case entails
CLINICAL LABORATORY
I. HEMATOLOGICAL TESTS
The CBC is used as a broad screening test to check for such disorders as
anemia, infection, and many other diseases. It is actually a panel of tests that
examines different parts of the blood and includes the following:
White blood cell (WBC) count is a count of the actual number of white
blood cells per volume of blood. Both increases and decreases can be
significant.
White blood cell differential looks at the types of white blood cells
present. There are five different types of white blood cells, each with its
own function in protecting us from infection. The differential classifies a
person's white blood cells into each type: neutrophils (also known as
segs, PMNs, granulocytes, grans), lymphocytes, monocytes, eosinophils,
and basophils.
Red blood cell (RBC) count is a count of the actual number of red
blood cells per volume of blood. Both increases and decreases can point
to abnormal conditions.
Hemoglobin measures the amount of oxygen-carrying protein in the
blood.
Hematocrit measures the percentage of red blood cells in a given
volume of whole blood.
The platelet count is the number of platelets in a given volume of blood.
Both increases and decreases can point to abnormal conditions of
excess bleeding or clotting. Mean platelet volume (MPV) is a machine-
calculated measurement of the average size of your platelets. New
platelets are larger, and an increased MPV occurs when increased
numbers of platelets are being produced. MPV gives your doctor
information about platelet production in your bone marrow.
Red Blood Cell: Decreased with anemia; increased when too many made
and with fluid loss due to diarrhea, dehydration burns.
A. Antibiogram
Before starting this treatment, the physician will collect a sample from a
suspected contaminated compartment: a blood sample when bacteria possibly
have invaded the bloodstream, a sputum sample in the case of ventilator
associated pneumonia, and a urine sample in the case of a urinary tract
infection. These samples are transferred to the microbiology lab, which looks at
the sample under the microscope, and tries to culture the bacteria. This can
help in the diagnosis.
Once the MIC is calculated, it can be compared to known values for a given
bacterium and antibiotic: e.g. a MIC > 0, 06 µg/ml may be interpreted as a
penicillin-resistant Streptococcus pneumoniae. Such information may be useful
to the clinician, who can change the empirical treatment, to a more custom-
tailored treatment that is directed only at the causative bacterium.
B. BLOOD CULTURE
Method
The blood is collected using clean technique. This requires that both the tops of
the culture bottles and the venepuncture site of the patient are cleaned prior to
collection with alcohol swabs containing 2% chlorhexidine and 70% isopropyl
alcohol.
After inoculating the culture vials, they are sent to the clinical pathology
microbiology department. Here the bottles are entered into a blood culture
machine, which incubate the specimens at body temperature. The blood culture
instrument reports positive blood cultures (cultures with bacteria present, thus
indicating the patient is "bacteremic"). Most cultures are monitored for 5 days
after which negative vials are removed.
If a vial is positive, a microbiologist will perform a Gram Stain on the blood for a
rapid, general ID of the bacteria, which they will report to the attending
physician of the bacteremic patient. The blood is also subcultured or "subbed"
onto agar plates to isolate the pathogenic organism for culture and suceptability
testing, which takes up to 3 days. This culture & sensitivity (C&S) process
identifies the species of bacteria. Antibiotic sensitivities are then assessed on
the bacterial isolate to inform clinicians on appropriate antibiotics for treatment.
Is a blood test for syphilis and was developed by the former Venereal Disease
Research Laboratory, now the Treponemal Pathogenesis and Immunology
Branch, of the United States Public Health Service. The VDRL type test was
invented before World War I, with its first iteration being that developed by
August Paul von Wasserman with the aid of Albert Neisser in 1906.
The VDRL test, as it is largely still done today, was developed in 1946 by
Harris, Rosenberg, and Riedel.
III. INMUNOLOGIC TESTS
The numbers and types of cells and/or material such as urinary casts can yield
a great detail of information and may suggest a specific diagnosis.
crystalluria -- associated with acute urate nephropathy (or "Acute uric acid
nephropathy", AUAN)
calcium oxalatin - associated with ethylene glycol toxicity
B. ANTIBODIES
A. ELECTROLYTE
Is any substance containing free ions that make the substance electrically
conductive. The most typical electrolyte is an ionic solution, but molten
electrolytes and solid electrolytes are also possible.
Is a chemical released by a cell in one part of the body, that sends out
messages that affect cells in other parts of the organism. Only a small
amount of hormone is required to alter cell metabolism. It is essentially
a chemical messenger that transports a signal from one cell to another.
All multicellular organisms produce hormones; plant hormones are also
called phytohormones. Hormones in animals are often transported in
the blood. Cells respond to a hormone when they express a specific
receptor for that hormone. The hormone binds to the receptor protein,
resulting in the activation of a signal transduction mechanism that
ultimately leads to cell type-specific responses.
C. BIOCHEMICAL PROFILE
A panel of tests, usually selected for their ability in the particular species to
evaluate the functional capacity of several critical organ systems and general
health. The 'profile' may literally be the results plotted on individual, parallel
numerical scales, producing a pattern similar to a bar grap.
RADIOLOGY
1. DEFINITION
3. CT SCANNING
4. ULTRASOUND
MRI uses strong magnetic fields to align atomic nuclei (usually hydrogen
protons) within body tissues, then uses a radio signal to disturb the axis of
rotation of these nuclei and observes the radio frequency signal generated as
the nuclei return to their baseline states plus all surrounding areas. The radio
signals are collected by small antennae, called coils, placed near the area of
interest. An advantage of MRI is its ability to produce images in axial, coronal,
sagittal and multiple oblique planes with equal ease. MRI scans give the best
soft tissue contrast of all the imaging modalities. With advances in scanning
speed and spatial resolution, and improvements in computer 3D algorithms and
hardware, MRI has become a tool in musculoskeletal radiology and
neuroradiology.One disadvantage is that the patient has to hold still for long
periods of time in a noisy, cramped space while the imaging is performed.
Claustrophobia severe enough to terminate the MRI exam is reported in up to
5% of patients. Recent improvements in magnet design including stronger
magnetic fields (3 teslas), shortening exam times, wider, shorter magnet bores
and more open magnet designs, have brought some relief for claustrophobic
patients. However, in magnets of equal field strength there is often a trade-off
between image quality and open design. MRI has great benefit in imaging the
brain, spine, and musculoskeletal system. The modality is currently
contraindicated for patients with pacemakers, cochlear implants, some
indwelling medication pumps, certain types of cerebral aneurysm clips, metal
fragments in the eyes and some metallic hardware due to the powerful
magnetic fields and strong fluctuating radio signals the body is exposed to.
Areas of potential advancement include functional imaging, cardiovascular MRI,
as well as MR image guided therapy.
Ultrasound
The Ultrasound uses sound waves of high frequency to look at organs and
structures within the body. Health professionals use them to see the heart,
blood vessels, kidneys, liver and other organs. During pregnancy, doctors use
ultrasound tests to examine the fetus. Unlike X-rays, ultrasound involves no
radiation exposure.
The radiation for cancer treatment comes externally, from special machines, or
internally, from radioactive substances that a doctor places in your body.
Sometimes radiation is used with other treatments, like surgery or
chemotherapy.
Diagnostic Imaging
Diagnostic imaging refers to technologies that doctors use to look inside your
body for clues about a medical condition. A variety of machines and techniques
can create pictures of the structures and activities inside your body. The
technology your doctor uses will depend on your symptoms and the part of your
body being examined. X-rays, CT scans, nuclear medicine scans, MRI scans
and ultrasound are all types of diagnostic imaging.
Many imaging tests are painless and easy. Some require you to stay still for a
long time inside a machine, though. This can be uncomfortable. Certain tests
involve radiation, but these are generally considered safe because the dosage
is very low.
For some imaging tests, a tiny camera attached to a long, thin tube is inserted
in your body. This tool is called a scope. The doctor moves it through a body
passageway or opening to see inside a particular organ, such as your heart,
lungs or colon. These procedures often require anesthesia.
OPHTHALMOLOGY
OTORHINOLARYNGOLOGY