RAWALPINDIMEDICALUNIVERSITY, RAWALPINDI

GIT LIVER AND

PARASITOLOGY MODULE

3rd
Year
MBBS

STUDY GUIDE
 INTEGRATED MODULAR CURRICULUM FOUNDATIONMODULE

GI MODULE

PLACEMENT IN CURRICULUM 2ndMODULE

MODULE DURATION 4 WEEKS

PRE-REQUISITE PRIORKNOWLEDGETOANATOMY,PHYSIOLOGY&B
IOCHEMISTRY

MODULE TEAM
CHAIRMAN CURRICULUMCOMMITTEE PROF. DR. MUHAMMAD UMAR
VICE CHANCELLOR RMU

MODULE PLANNER DR OMAIMA ASIF

MODULE COORDINATOR DR AASIYA NIAZI

MODULE CO-COORDINATORS DR ALI, DR HAIDER

 INTEGRATED MODULAR CURRICULUM FOUNDATIONMODULE

MODULE COMMITTEE

PROF. DR. NAEEM AKHTER DEAN OF BASIC SCIENCES/ CONVENER

PROF. DR IDREES ANWAR DEANOFSURGERY/MEMBERCURRICULUMCOMMITTEE

PROF DR SEEMI GUL INCHARGE IMPLEMENTATION OF INTEGRATED

CURRICULUM 3RD YEARMBBS

DR ATTIYA MUNIR FOCAL PERSON (PHARMACOLOGY)

DR SYEDA FATIMA RIZVI FOCAL PERSON (PATHOLOGY)

DR SAJID HAMEED FOCAL PERSON (FORENSICMEDICINE)

DR SAIMA AMBREEN FOCAL PERSON (MEDICINE)

DR YASMEEN IQBAL FOCAL PERSON (SURGERY)

DR AFIFA KALSOOM FOCAL PERSON (COMMUNITY MEDICINE)

DR ASAD SHABBIR FOCAL PERSON (PAEDS)

 INTEGRATED MODULAR CURRICULUM
INTRODUCTION/RATIONALE
FOUNDATIONMODULE
Gastrointestinal tract & Hepatobiliary system plays a pivotal role in
the body of Human being. There are three main functions of the
gastrointestinal tract, including transportation, digestion, and
absorption of food. The mucosal integrity of the gastrointestinal
tract and the functioning of its accessory organs are vital in
maintaining the health of the person. Alongside heaptobiliary
system aids in this process of digestion and absorption.
Students at this level have profound knowledge of anatomical,
physiological and biochemical aspects of this system as they have
gone through it in the GIT module in 1st & 2nd Year MBBS.
Students in the current module shall be able acquire the
understanding of diseases of GIT and liver and their management.
Parasitology is the branch of Pathology which deals with the study of
certain parasites and the diseases caused by them. Students in this
section will also get knowledge regarding parasites and diseases
pertaining to it.
 Student at the end of this Module will be able to:
 Describe the pathogenesis and management of diseases
related to GIT.
 Enlist the drugs used in the Gastrointestinal &
hepatobiliary disorders.
 Discuss medical aspects of common diseases related to
GIT & liver.
 Know about the parasites and diseases caused by them.
MODULE OUTCOMES  Management of parasitic diseases prevalent in our
community.
 Study Guide GI Module 2019-2020
Code Leaning Objectives
Topic Discipline
No Knowledge Skill Attitude
At the end of the lecture students should be able to
L1 Anatomy of GIT Revision  Describe the general organization and topography of Gastrointestinal
tract.
 Explain abdominal wall, peritoneum and viscera of Gastrointestinal tract.
 Discuss neurovascular organization and lymphatic drainage of
Gastrointestinal tract.

S1 Sulfuric Acid Forensic  Describe the physical properties of Sulfuric Acid (H2SO4) Corrosive Alkalis.
Corrosive Alkalis Medicine  Describe the source of Sulfuric Acid Corrosive Alkalis available for any
type of poisoning (suicidal, homicidal, accidental) Describe mechanism of
action in humans.
 Describe the clinical features of Sulfuric Acid Corrosive Alkalis.
 Describe the fatal dose and management of Sulfuric Acid Corrosive Alkalis
poisoning.
 Describe the Medicolegal importance of Sulfuric Acid Corrosive Alkalis
poisoning.
 Discuss the autopsy findings of a victim of Sulfuric Acid Corrosive Alkalis
poisoning.
L2 Oral Cavity Pathology  Describe Causes and pathological features of Inflammatory/ reactive
& Salivary Lesions Aphthous Ulcers (Canker Sores), Fibrous Proliferative Lesions and
Gland Infections.
Pathology  Explain oral Manifestations of Systemic Disease with examples.
 Explain causes and pathogenesis of Precancerous and Cancerous Lesion.
 Discuss epidemiology, causes and cytomorphological features of
Squamous Cell Carcinoma and Odontogenic tumors
 Classify salivary gland non neoplastic lesions.
 Discuss Xerostomia and Inflammation (Sialadenitis).
C1 Salivary Pathology  Discuss the epidemiology, causes and cytomorphological features of
Gland Tumor salivary gland tumors.
 Classify salivary gland tumors.
 Apply diagnosis on the basis of morphology of following tumors
Pleomorphic adenoma, Warthin tumor, Mucoepidermoid Carcinoma.

S2 Congenital Pathology  Describe pathological features of Atresia, Fistulae, and Duplications,
Anomalies of GI Diaphragmatic Hernia, Omphalocele, Meckel Diverticulum, and Pyloric
and Esophageal Stenosis.
Diseases  Discuss pathological features of achalasia.
 Enlist different types of Esophagitis.
 Describe Lacerations, chemical and Infectious esophagitis’s and
morphological diagnosis of Eosinophilic esophagitis.
L3 Antiemetic Pharmacology  Classify anti-emetics
 Describe the mechanism of action of Metoclopramide
 Describe the uses & adverse effects of Metoclopramide
 Describe mechanism of action and adverse effects of other anti-emetics
(5HT3 antagonists, H1 antagonists & hyoscine.
 Give therapeutic classification of anti-emetics
L4 Neoplastic Pathology  Describe etiology, pathogenesis and morphological features of Reflux
Lesions Esophagitis, Esophageal Varices, Barrett’s Esophagus.
of Esophagus  Classify different types of esophageal tumors on the basis of morphology.
L5 Introduction, Medicine  Describe different symptoms of gastrointestinal disease and their Acquire accurate
Symptoms and differential diagnosis. history from
Analysis of GI  Discuss different investigations of Gastrointestinal diseases. symptoms.
Investigation  Discuss indications and interpretation of different tests used for
Gastrointestinal diseases.

L6 Esophageal Surgery  Outline differential diagnosis of dysphagia

Disease  Describe different types of Motility disorders of esophagus.
 Explain clinical features, diagnosis, treatment and complications
associated with GERD.
 Describe pathophysiology, diagnosis and treatment options for different
benign causes of dysphagia
 Describe pathophysiology, diagnosis and treatment options for carcinoma
esophagus.
S3 Introduction to Pathology  Define and Differentiate between
Parasitology  Definitive host
 Intermediate host
 Vector
 Carrier state
 Reservoir
 Symbiosis
 Mutualism
  Forms in which parasites exist
 Classification of medically important parasites
C2 Prokinetics Pharmacology  Define Prokinetic drugs
 Classify the group of drugs that are used as Prokinetics
 explain the , MOA uses and adverse effects of D2 blockers drugs
 discuss drugs of other groups as well
L7 Types of Gastritis Pathology  Describe causes, pathogenesis and morphological features of gastropathy
and and Acute Gastritis, Chronic Gastritis.
Gastropathies  Differentiate morphological features of Helicobacter pylori Gastritis and
Autoimmune Gastritis.
 Describe Causes, Pathogenesis and morphological features of Intestinal
Metaplasia, Dysplasia, Gastritis Cystica, Hypertrophic Gastropathies.
 Explain causes, Pathogenesis and morphological features of Ménétrier
Disease and Zollinger-Ellison Syndrome.
L8 Approach to A Medicine  Define dyspepsia in terms of organic and functional dyspepsia
Patient With  Understand the epidemiology and diversity of dyspeptic symptoms
Dyspepsia  Discuss the heterogeneous pathophysiology underlying functional
dyspepsia
 Describe the role of psychosocial factors in the pathogenesis of dyspeptic
symptoms
 Discuss symptoms of dyspepsia frequently overlap with other (upper)
gastrointestinal conditions, making accurate symptomatic diagnosis
challenging
C3 H.Pylori Gastritis Pathology  Describe the pathogenesis of Peptic ulcer disease and relate it with its
and Peptic Ulcer morphology and clinical presentation.
 Correlate the etiology & pathogenesis of Helicobacter pylori-associated
chronic gastritis with clinical presentation.
 Enlist the complications and other diseases caused by H.Pylori infection.
L9 Drugs Used in Pharmacology  Classify drugs used in the treatment of Peptic Ulcer
Peptic Ulcer 1  Describe the mechanism of action of antacids used in the treatment of
Peptic Ulcer
 Describe the adverse effects of antacids
L10 Cestodes 1 Pathology  Classify the cestodes. Identify the egg/ova Importance of
 Describe morphological features of cestodes. on stool examination proper history
taking and stool
 Enlist diseases caused by each type
examination in
 Describe life cycle of these parasites. diagnosis
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
  Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
L11 Drugs Used in Pharmacology  Describe the mechanism of action of H2 receptor blockers
Peptic Ulcer 2  Describe the adverse effects of H2 Receptor Blockers
 Tabulate differences between cimetidine & other H2receptor blockers
 Describe the mechanism of action of Proton Pump Inhibitors
 Describe adverse effects of PPIs
L12 Definition of Community  Define nutrition
Nutrition – Medicine  describe food pyramid
Classification of  utilize food pyramid
Foods  classify food according to function
 classify food according to nutritive value
 classify food according to origin
 classify food by chemical composition
P1 Construct the
 Discuss the components of prescription prescription for
Introduction to P Pharmacology  Describe various steps of P-Drug specific diseases
drugs and
prescription Select appropriate P
writing drug for specific
disease
P2  Recognize and draw histopathological features of pleomorphic adenoma Identify the slides
of parotid gland. and recognize two
Salivary tumor, Pathology  Describe the pathological features of gastric ulcers and carcinoma of points of
CA esophagus, esophagus and stomach. identification of
peptic ulcer, CA pleomorphic
stomach adenoma, CA
stomach and CA
esophagus.
 SECOND WEEK
C4 Drugs Used in Pharmacology  Discuss the mechanism of action of Mucosal protective agents
Peptic Ulcer 3  Discuss adverse effects of Mucosal protective agents
 Discuss the drugs used for eradication of H. Pylori infection
L13 Neoplastic Lesion Pathology  Classify different types of gastric Polyps Identify gross and
of Stomach  Explain epidemiology, etiology, Pathogenesis of CA Stomach microscopic images
 Diagnosis of Gastric adenocarcinoma Morphology of gastric
adenocarcinoma
L14 Small Intestinal Pathology  Describe Causes, Pathogenesis and morphological features Intestinal
Disease Obstruction
 Discuss causes, pathogenesis and diagnosis of Malabsorption and
Diarrhea.
 Explain Pathogenesis and diagnosis of Cystic Fibrosis
 Laboratory diagnosis of Celiac disease
L15 Types of Colitis Pathology  Describe causes, pathogenesis and morphological features Inflammatory Identify microscopic
and IBD Bowel Disease images of
 Differentiate between Ulcerative colitis and crohn’s disease, Microscopic inflammatory bowel
Colitis and Graft-Versus-Host Disease disease.
C5 Drugs Used in IBD Pharmacology  Enlist drugs used in IBD.
 Describe the therapeutic pyramid approach to inflammatory bowel
disease and how treatment choice is made.
C6 Drugs Used in IBD Pharmacology  Enlist drugs used in IBD.
 Describe the therapeutic pyramid approach to inflammatory bowel
disease and how treatment choice is made.
L16 Approach to a Medicine  Define hematemesis, melena and hematochezia.
Patient with  Define, describe, and prioritize the common causes for symptoms of
Upper upper GI Bleed including Esophagitis/esophageal erosions, Mallory Weiss
GI Bleed tear, Peptic and duodenal ulcer disease and tumor.
 Define and describe the distinguishing features of upper versus lower GI
bleeding
 Recommend laboratory and diagnostic tests to evaluate GI bleeding
L17 Acute Abdomen Surgery  Describe clinical presentation (S/S) of acute surgical abdomen.
(peritonitis, intestinal obstruction, appendicitis etc.)
 Enlist differential diagnosis of acute abdominal presentations based on
clinical presentation.
 Apply this theoretical knowledge to make management plan including
diagnosis and treatment plan for traumatic (blunt and penetrating) and
non traumatic presentations of acute abdomen.
C7 Diarrhea causing Pathology  Describe transmission & Life cycle Identify etiological
protozoa  Enlist Clinical features of intestinal Amoebiasis cause of diarrhea on
the basis of clinical
 Explain Extra intestinal amoebiasis
features and
 Interpret Lab diagnosis morphology of fecal
 Differentiate between amebic and bacillary dysentery specimen.
 Plan treatment & prevention
 Describe life cycle and diseases caused by Giardia and enlist other non
pathogenic amoebas.
 Describe clinical features of diarrhea caused by different protozoa
L18 Cestodes 2 Pathology  Classify the cestodes. Identify the egg/ova
 Describe morphological features of cestodes. on stool
 Enlist diseases caused by each type examination
 Describe life cycle of these parasites.
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
L19 Antiamebic Drugs Pharmacology  Classify amoebic drugs
1  Describe their mechanism of action
 Describe MOA, other uses and adverse effect of metronidazole
 Discuss important drug interactions of metronidazole.
L20 Approach to a Medicine  Should be able to define ascites
Patient With  Classify according to the normal or the diseased peritoneum e.g. normal
Ascites and peritoneum causes are heart failure, cirrhosis, nephrotic syndrome and
Abdominal disease peritoneum causes are infection and malignancy
Distention  Discuss Pathophysiology of ascites
 Discuss and describe Clinical features of ascites as symptoms of
abdominal distention, pain, bloating, dyspnea

L21 Abdominal Surgery  Recognize different types of abdominal hernias

Hernias  Describes management plan for each type of hernia.
 Explain possible complications associated with hernias
L22 Neoplastic Pathology  Classify intestinal inflammatory and neoplastic Polyps. Identify tumor of
Lesions  Describe syndromic association of polyps. colon on gross
of Intestine  Discuss epidemiology, etiology, Pathogenesis and morphological features examination
of intestinal Tumors.
 Explain genetic etiology and molecular pathogenesis of colorectal Identify the slide of
adenocarcinoma. colorectal
 Describe hereditary Non-Polyposis Colorectal carcinoma. adenocarcinoma
 Enumerate staging of colorectal Adenocarcinoma

C8 Colorectal Pathology  Discuss differential diagnosis based on clinical and morphological Identify tumor of
Carcinoma features. colon on gross
 Classify intestinal inflammatory and neoplastic Polyps. examination
 Explain genetic etiology and molecular pathogenesis of colorectal Identify the slide of
adenocarcinoma. colorectal
 Describe hereditary Non-Polyposis Colorectal carcinoma. adenocarcinoma
 Enumerate staging of colorectal Adenocarcinoma
L23 Ant amoebic Pharmacology  Classify amoebic drugs
Drugs  Describe their mechanism of action
 Describe MOA, other uses and adverse effect of metronidazole
 Discuss important drug interactions of metronidazole.
S4 Trematodes: Pathology  Enlist Diseases caused by each type with Characteristics.
Schistosoma  Comprehend life cycle, transmission epidemiology& pathogenesis
 Interpret Laboratory diagnosis
 Plan treatment and prevention
Write a suitable
prescription for a
P3 P Drugs/ patient of H.pylori
prescription Pharmacology  Recall the drug groups used in peptic ulcer disease induced peptic ulcer
writing of peptic
Select a suitable P
ulcer
drug for a patient of
peptic ulcer disease
Describe the physical properties of Arsenic and Mercury. Identify specimen of The student will
Describe mechanism of action in humans. Arsenic and Mercury be able to
P4 Describe the clinical features of Arsenic and Mercury poisoning and its establish a case of
Arsenic Mercury Forensic management. Arsenic and
Medicine Describe the Medicolegal importance of Arsenic and Mercury poisoning. Mercury
 Describe the autopsy findings of a victim of Arsenic and Mercury poisoning and
poisoning. perform duty as
 CMO.

Identify the slides

and recognize two
Acute
P5 Pathology  Recall pathological features of acute appendicitis. important points of
appendicitis
Intestinal TB  Differentiate between Intestinal tuberculosis and IBD. identification of
acute appendicitis
Crohn’ disease
Intestinal TB
CA colon
Crohn’ disease
And CA colon.

Third week
L24 Anal Canal, Pathology  Describe epidemiology, Pathogenesis and morphology of Tumors of the
Appendix and Anal Canal
Peritoneum  Apply morphological diagnosis of acute Appendicitis
 Classify tumors of the Appendix on the basis of morphology.
S5 Phosphorus and Forensic  Describe the physical properties of
Copper Medicine  phosphors and copper.
 Describe the source of phosphors and copper available for any type of
poisoning (suicidal, homicidal, accidental)
 Describe mechanism of action in humans. Describe the clinical features of
phosphors and copper poisoning
 Describe the fatal dose and management of phosphors and copper
poisoning.
 Describe the Medicolegal importance of phosphors and copper poisoning.
 Describe the autopsy findings of a victim of phosphors and copper
poisoning.
L25 Types of hepatitis Pathology  Discuss etiology, pathogenesis, laboratory diagnosis of autoimmune
and metabolic Hepatitis
liver disease  Describe Drug- and Toxin-Induced Liver Injury
 Enumerate morphological features of alcoholic Liver Disease Non-
alcoholic Fatty Liver Disease Disease (NAFLD)
 Enlist causes and morphological features of metabolic Liver Disease
(Hemochromatosis, Willson Disease, α1-Antitrypsin Deficiency)
L26 Nutrition 2 Community  Describe major food groups
medicine  Discuss functions of proteins
 Describe requirements and sources of proteins
 Explain functions of carbohydrates
 Describe requirements and sources of carbohydrates
  Discuss functions of fats
 State requirements and sources of fats
S6 Trematodes: liver Pathology  Classify the different important types of flukes.
& lung flukes  Enlist diseases caused by each type
 Describe life cycle of these parasites.
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
C9 Hydatid Disease Pathology  Enlist diseases caused by each type
 Describe important features of life cycle of these parasites.
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
L27 Antiviral drugs 1 Pharmacology  Discuss drug used for treatment of Hepatitis B and C viral infections
 Discuss the mechanism of action, uses and adverse effects of interferon
 Discuss drug used in the HAART regime
L28 Approach to a Medicine  Understand the different causes of pre-hepatic, hepatic, and post hepatic
Patient with jaundice and pathophysiology
Jaundice  Take a thorough history and examination, and arrange appropriate initial
investigations to arrive at a valid differential diagnosis of jaundice
 Recognize the presence of acute (fulminant) liver failure and chronic liver
disease

L29 Obstructive Surgery  Explain signs and symptoms of cholelithiasis, chronic cholecystitis, acute
Jaundice and cholecystitis, cholangitis, pancreatitis and obstructive jaundice.
Hepatobiliary  Enlist a D/D for upper abdominal pain.
Diseases  Enlist a D/D for obstructive jaundice.
 Apply his theoretical knowledge to make a management plan for
hepatobiliary diseases.
L30 Liver Cirrhosis Pathology  Discuss causes, Pathogenesis and morphological features of Cirrhosis and Identify the gross
Portal Hypertension. images of cirrhotic
 Enumerate causes of chronic hepatitis liver.
 Interpret morphological diagnosis of cirrhosis by neuroinflammatory
grade and stage.
 Corelate morphological diagnosis of cirrhosis with clinical outcome of
 disease.

S7 Gall Bladder Pathology  Discuss morphological features of Congenital Anomalies Identify the
Diseases  Describe etiology and pathogenesis of Cholelithiasis (Gallstones) microscopic images
Cholecystitis of chronic
 Classify neoplastic lesions of gall bladder Cholecystitis&
Carcinoma gall
bladder
L31 Jaundice and Pathology  Discuss pathophysiology of Jaundice, Cholestasis, large Bile Duct
Biliary Diseases Obstruction autoimmune Cholangiopathies
 Differentiate between pathological features of Primary Biliary Cirrhosis
(PBC) and Primary Sclerosing Cholangitis (PSC)
 Discuss Structural Anomalies of the Biliary tree, biliary atresia
 Explain Portal Vein Obstruction and hepatic vein Thrombosis
 Describe Graft-Versus-Host Disease and Liver Graft Rejection
L32 Hepatitis A,C And Pathology  Enumerate the important properties & Diseases caused by these viruses
E  Describe the Replicative cycle
 Explain the transmission of the diseases caused by these viruses
 Relate the interaction of pathogenesis of viruses & immunity of
individuals
 Identify clinical findings of the diseases caused by these viruses
 List the laboratory identification
 Describe the treatment &Prevention
L33 Hepatitis B and D Pathology  Explain the important properties & Diseases caused by these viruses
 List serological markers of hepatitis B
 Describe the Replicative cycle
 Describe the transmission of the diseases caused by these viruses
 Relate the interaction of pathogenesis of viruses & immunity of
individuals
 Identify clinical findings of the diseases caused by these viruses
 List laboratory identification
 Describe the treatment & Prevention
L34 Approach to a Medicine  Define liver cirrhosis
Patient with Liver  Discuss different causes of liver cirrhosis
Cirrhosis  Recognize different complications of liver cirrhosis, including ascites,
variceal hemorrhage, hepatic encephalopathy.

L35 Liver transplant Surgery  Discuss Indications for liver transplantation

surgery related to  Enlist contraindications for liver transplantation (absolute and relative)
 cirrhosis  Describe types of liver transplantation.
 Explain complications of liver transplant surgery.
L36 Preventive Community  Explain different types of Hepatitis
measures of viral medicine  Describe causes of different types of Hepatitis
hepatitis  Elaborate the modes of transmission of different types of Hepatitis
 Describe the prevention of different types of Hepatitis
 Design control activities for different types of Hepatitis
 Guide people about immunization against different types of Hepatitis

L37 Antiviral drugs 2 Pharmacology  Discuss drug used for treatment of Hepatitis B and C viral infections
 Discuss the mechanism of action, uses and adverse effects of interferon
 Discuss drug used in the HAART regime
P6 Prescription and P pharmacology  Recall the drugs used in amoebic dysentery Describe suitable
drugs of amoebic drugs for the patient
dysentery with amoebic
dysentery
P7 Stool Pathology  Describe importance of stool examination. Identification of
examination/  Differentiate common parasite ovas on basis of morphology. common pathogens
Parasitology  Describe sample collection and transportation. and parasites &
(practical) eggs/ ova

Fourth week
S8 Minor protozoa: Pathology  Enlist diseases caused by each type
acanthamoeba,  Describe important features of life cycle of these parasites.
naegleria  Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
L38 Anthelminthic Pharmacology  Classify anthelmintic therapeutically
Drugs  Explain mechanism of action of each group
 Explain their advance effects
 Explain their mode of administration
L39 Neoplastic Liver Pathology  Discuss etiology, pathogenesis and morphology of Nodular Hyperplasia’s, Identify the gross
Hepatocellular Adenomas and Hepatoblastoma. images of liver
 Discuss Hepatocellular Carcinoma (HCC), Cholangiocarcinoma (CCA), tumor.
Other Primary Hepatic Malignant Tumor on basis of morphology
L40 Anthelminthic Pharmacology  Classify anthelmintic therapeutically
Drugs
  Explain mechanism of action of each group
 Explain their advance effects
 Explain their mode of administration
L41 Nematodes: Pathology  Classify the Nematodes.
intestinal  Classify the Intestinal Nematodes.
nematodes  Describe the common and differentiating features in morphology and life
cycle of the Nematodes
 Enlist diseases caused by each type
 Describe life cycle of these parasites.
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
S9 Diseases of Pathology  Describe morphological features of Congenital Anomalies
Pancreas  Discuss etiology, pathogenesis and morphological features of acute
Pancreatitis and chronic Pancreatitis.
 Classify pancreatic Cysts.
 Classify pancreatic benign and malignant tumors
L42 Vitamins, Community  At the end of lecture
Minerals Medicine  students will be able to:
 explain importance of major minerals
 explain importance of trace elements
 State different types of vitamins explain functions of vitamins
 explain functions of minerals
 state daily requirement of vitamins
 state daily requirement of minerals
 describe deficiency diseases of vitamins and minerals
L43 Pancreatitis Surgery  Describe signs and symptoms of cholelithiasis, chronic cholecystitis, acute
cholecystitis, cholangitis, pancreatitis and obstructive jaundice.
 Enlist a D/D for upper abdominal pain.
 Enlist a D/D for obstructive jaundice.
 Apply his theoretical knowledge to make a management plan for
hepatobiliary diseases.
L44 Nematodes: Pathology  Enumerate Tissue Nematodes.
tissue nematodes  Describe the morphological features of the tissue nematodes
 Enlist diseases caused by each type
 Describe life cycle of these parasites.
  Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
S10 Drugs Used in Pharmacology  Discuss the symptomatic treatment of diarrhea & constipation
Irritable Bowel  Explain specific drug for diarrhea predominant & constipation
Syndrome predominant IBS. & their limited use because of adverse effects
C10 Nematodes: Pathology  Enumerate Nematodes with disease causing larvae.
nematodes with  Describe the morphological features
disease causing  Enlist diseases caused by each type
larvae  Describe life cycle of these parasites.
 Explain transmission, epidemiology
 and Pathogenesis of diseases caused by them.
 Explain the diagnosis on the basis of clinical features and laboratory
findings.
 Describe treatment and prevention.
L45 Medical Aspects Medicine  Discuss the various types of parasites and hosts.
of • Explain the relationship between a parasite and the host and their effects.
Parasitology  Discuss in detail the classification of medically important parasites.
 Explain the difference between the Cestodes, Nematodes, Trematodes
and Protozoa.
L46 Surgical Aspects Surgery  Enlist surgically important parasites
of Parasitology  Describe Diagnostic criteria and management
 Discuss Emergency presentations of parasitic infections
 Discuss surgical management of parasitic infestation
S11 Laxatives Pharmacology  Define Laxative, Purgatives &Cathartics
 Classify Purgatives
 Describe the clinical benefits of the use of Purgatives
 Describe the mechanism of action & Adverse effects of Bulk Purgatives
 Describe the mechanism of action, uses of osmotic laxatives
 Enumerate uses& adverse effects of Osmotic laxatives
 Describe the role of Lactulose in the treatment of Hepatic Encephalopathy
 Describe the mechanism of action of fecal softeners
 Enumerate adverse effects of Liquid Paraffin
 Describe the mechanism of action of stimulant purgatives
 Enumerate adverse effects of Stimulant Purgatives
L47 Microbes causing Pathology  Enlist different GI infections caused by bacteria
 GI infections  Enlist the important bacteria responsible for causing GI infections
 Explain the clinical features of different GI infections of bacterial etiology.
 Describe the transmission and pathogenesis
 Explain the lab diagnosis
 Explain the treatment and prevention.
S13 Minor protozoa: Pathology  Explain the important morphological features of the organisms.
toxoplasma,  Enlist the diseases caused by the organisms
trichomonas  Describe the life cycle of the organisms
 Describe the transmission and pathogenesis
 Explain the diagnosis, treatment and prevention.
L49 Malnutrition, Community  classify malnutrition
Blame Diet Medicine  explain causes of malnutrition
 discuss prevention of different types of malnutrition
 define nutritional surveillance, food fortification, food adulteration
 discuss balance diet
 describe energy requirement
 discuss concept of empty calories
P8 Prescription and P pharmacology  Recall the drugs used in worm infestations. Write a suitable
writing of prescription for
antihelminthic patient with
drugs Ascariasis &
Enterobious
Vermicularis.

P9 Autopsy visit Forensic  Describe the contents of Medicolegal/postmortem reports. Preparation of The student will
/Postmortem/ medicine  Describe the requirements of a mortuary. MLC/autopsy report. be keen enough
Medicolegal work  Describe the classification of pattern of injuries in MLC cases. to highlight and
 Observe autopsy and Medicolegal case management at DHQ, Hospital. express his/her
obligations
towards cases of
Medicolegal
injuries and
deaths
P10 Fatty change, Pathology  Recall important histomorphology features for diagnosis of fatty change, Identify the slides
Cirrhosis, CA liver Cirrhosis, CA liver and recognize two
points of
identification of
Fatty change,
Cirrhosis, CA liver