TEST FOR NURSES IN DIPLOMA LEVEL

PHARMACOLOGY

Instructions:

a) This examination consists of sections A, B, C and D.

b) Section A consists of twelve(12) multiple choice questions, Section B consists of eight true and
false, Section C consists of four(4) short answers questions and section D consists of two (2)
Essay type questions, you are supposed to answer all questions in each section

c) The weight of each question is indicated in the respective sections

d) Cellular phones are not allowed in the examination room.

e) Write your number on every page of answer sheets/ question paper

SECTION A: MULTIPLE CHOICE QUESTIONS (1mark each)

1. The following routes of drug administration avoid first pass metabolism EXCEPT

A) Oral route

B) Intramuscular route(I.M)
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 C) A and B Are correct

D) Intravenous route (I.V)

2. The following drug can be given in rectal route

A) Vancomycin

B) Penicillin

C) Vincristine

D) Metronidazole

3. The following group of penicillin is subjected to gastric acid in the stomach

A) Temocillin

B) Phenoxymethylpenicillin

C) Benzylpenicillin

D) Ampicillin

4. The following penicillin is in group of penicillinase resistant penicillins EXCEPT

A) Cloxacillin

B) Flucloxacillin

C) Temocillin

D) Ticarcillin

5. The nurse in the afternoon shift has received a report of one patient who is seriously sick, and
one of the drug prescribed was gentamycin. Which of the following statements is most correct
and applicable concerning the above situation

A) The best route to administer gentamycin is intravenous

B) The best route to administer gentamycin is intramuscular

C) Gentamycin can also be given through the oral route

D) The route of drug administration does not depend on the desired effect of the given drug.

6. The following group of cephalosporins is in third generation

A) Ceftriaxone
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 B) Cefodizime

C) Cephradine

D) Cefaclor

7. The following drug can be given as an alternative if the client is allergic to penicillin

A) Ceftriaxone

B) Chloramphenical

C) Gentamycin

D) A and C

8. The drug which has greater dilution and at the same time achieve a powerful effect is said to be
A) Has low affinity

B) Low potency and high affinity

C) High affinity and high potency

D) High efficacy

9. The following rules apply when drug is administered to the patient EXCEPT:-

A) Availability of two nurses

B) The expired drug is given to the client only if the drug is within three month of the expiry date

C) Read the patient full name from prescription sheet

D) If the drug is not given to client record should be kept

10. The route which is used to test for sensitivity to allergens and immunization is:-

A) Intradermal injection

B) Subcutaneous injection

C) Intramuscular injection

D) Intravenous injection

11. Subcutaneous injection can accommodate amount of drug in …… mls:-

A) 0.1 or less

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 B) 0.5-2

C) 2-5

D) 0.1 or Above

12. Hadralazine is available in 20mg in 2mls ampule. The pregnant mother with eclampsia ordered
to receive 10mg prn when diastolic pressure is above 110mmHg. How many mls will she receive
for each episode:-

A) 0.5

B) 2

C) 10

D) 1

SECTION B: TRUE AND FALSE , Infront of the following sentence put T if it is true and F if it is
false. 1mark each

13. Pivampicillin is in the group of extended spectrum penicillin.

14. Side effects caused by penicillin can also be attributed by ceftriaxone

15. Drug tolerance It is commonly seen with CNS depressants and stimulants

16. Drugs returned by outpatients should be checked in pharmacy department first and used .

17. Only controlled drugs should be recorded when are given to clients

18. One centimeter cube of the liquid is approximately equivalent to one milliliter.

19. The cell wall of Gram-negative organisms is less complex compared to that of Gram-positive.

20. All β-lactam antibiotics interfere with the synthesis of the bacterial cell wall peptidoglycan.

SECTION C: SHORT ANSWER QUESTIONS

21. A) Define the following terms as applied in pharmacology

i) Therapeutic index

ii) Drug tolerance

iii) Drug elimination (3marks)

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 B)Mention two drugs which are in group of macrolide (2marks)

22. A) Describe the main factor which affect the absorption of the oral administered drugs.
(4marks)

B)Briefly describe the main routes by which drugs and their metabolites leave the body.

( 6marks)

23. A. Mention three side effects of the following group of drug

i) Benzylpenicillin ii) Gentamycin (6marks)

B. List in brief four(4) clinical uses of sulfonamides

24. Describe the basic rules governing the controlled drugs in hospital. (6marks)

SECTION C: ESSAY TYPE QUESTIONS

25. Describe the following groups of drugs in terms of mode of action, three (3) examples of drugs
in the group, three clinical uses and side effects:-

A)Fluoroquinolones B)Broad spectrum penicillin (25marks)

26. A. Describe the role of nurse in drug administration (15marks)

B. Benzylpenicillin available in powder form of 5MU. A child with pneumonia was ordered to be

Given 0.5MU 6hrly for 5days. How many mls of benzylpenicillin will you give.( Benzylpenicillin
require 4mls of water for injection).(5marks)

C.Calculate the amount to give the client if prescribed 50 micrograms but the strength available
is 500micrograms in 2ml.(5marks)

AUTHOR: SHANGO,N -----BSN(MUHAS)