60 Side Effects Every Pharmacist

Should Know
Side Effects Medicine
Ototoxicity Aminoglycosides
Nephrotoxicity
Tooth discoloration Tetracyclines
Photosensitivity
Esophageal irritation
Intracranial hypertension
Esophageal irritation Bisphosphonates
Hypophosphatemia
Osteonecrosis of the jaw
Atypical femoral fracture
Hemorrhagic cystitis Cyclophosphamide
Ifosfamide
Hypotension PDE5 inhibitors
Nasal congestion
Headache
Dizziness
Tachycardia
Rhabdomyolysis Statins
Diabetes
Elevated liver enzymes
Skin rash, sometimes SJS/TEN Lamotrigine
Pyridoxine deficiency Isoniazid
Peripheral neuropathy
Hepatotoxicity
Blue-gray skin discoloration Amiodarone
Pulmonary toxicity
Thyroid abnormalities
Photosensitivity
Corneal microdeposits
Ototoxicity Vancomycin
Nephrotoxicity
Hepatotoxicity
Blood disorders – thrombocytopenia
Red man syndrome
Conchonism Quinine
Deafness
Blindness
QT prolongation
Tendon rupture Fluoroquinolones
QT prolongation
Lowering seizure threshold
Steroid-induced diabetes Corticosteroids
Osteoporosis
Mood / behavioral changes
Hypertension, hypokalemia
Edema
Immunosuppression
Constipation Opioids
Euphoria
Respiratory depression
Itch
Pupillary constriction
Weight loss Metformin
Lactic acidosis
Vitamin B12 deficiency
Gastrointestinal upset
Gastrointestinal upset Trimethoprim
Hyperkalemia
Elevated creatinine levels
Megaloblastic anemia
Gingival enlargement Phenytoin
Hirsutism
Osteomalacia
Skin coarsening / acne
Nystagmus / ataxia
Purple glove syndrome
Persistent, dry cough ACE inhibitors
Hyperkalemia
Hypotension
Renal failure
Bleeding Aspirin
Stomach ulcers
Reye syndrome (under 16s)
Tinnitus (high doses)
Black stools Iron supplements
Black tongue, black stools Bismuth subgallate
Shake and bake’ reaction‘ Amphotericin B
Hypokalemia
Myocarditis
Hepatotoxicity
Kidney damage
Hypothyroidism Lithium
Diabetes type 2
Kidney damage
Weight gain
Myoclonus
Hyperglycemia Clofazimine
Brown-pink skin discoloration
Skin dryness, rash
Red-green color blindness Ethambutol
Optic neuritis
Hepatotoxicity
Peripheral neuropathy
Hyperuricemia
Agranulocytosis Clozapine
Myocarditis
Hypersalivation
CNS effects
Urinary incontinence
GI hypomotility
Bone marrow suppression
Weight disturbance SSRIs
Gastrointestinal upset
QT prolongation
Hyponatremia
Bone fractures
Serotonin syndrome
Lower seizure threshold
Tachycardia Antimuscarinics
Dry mouth
Blurred vision
Urinary retention
Constipation
Drowsiness
Tachycardia Beta-2 agonists
Palpitations
Anxiety
Tremors
Muscle cramps
Hypokalemia
Sweating
Insomnia
Agitation
Extrapyramidal side effects Typical
QT prolongation antipsychotics
Sexual dysfunction
Weight gain Atypical
Diabetes type 2 antipsychotics
Lipid abnormalities
Extrapyramidal effects
Drowsiness, sedation Benzodiazepines
Respiratory depression
Amnesia
Decreased concentration
Gastrointestinal bleeding NSAIDs
Renal impairment
Fluid retention
Photosensitivity
Bronchospasm Beta blockers
Vivid dreams / nightmares
Cold extremities
Hypoglycemia
Agranulocytosis Methimazole
Constipation Calcium channel
Gingival overgrowth blockers
Ankle swelling
Flushing
Hepatotoxicity Rifampin
Red urine, sweat, tears
Hepatotoxicity Methotrexate
Ulcerative stomatitis
Infections
Pulmonary fibrosis
Extreme diarrhea Irinotecan
Hearing loss Cisplatin
Kidney damage
High risk of vomiting
Bone marrow suppression Flucytosine
Loss of appetite
Psychosis
Renal damage
QT prolongation Macrolides
GI effects
Ototoxicity (high doses)
Cholestatic jaundice
Bleeding Heparin
Thrombocytopenia (heparin) Warfarin
Antiplatelets
Anticoagulants
Weight loss Levothyroxine
Trouble sleeping
Tachycardia
Anxiety
Difficulty tolerating heat
Palpitations
Phocomelia / limb deformities Thalidomide
Pulmonary toxicity Carmustine
Busulfan
Severe anaphylaxis Iron dextran
Hand-foot syndrome Capecitabine
Uterine cancer Tamoxifen
Pulmonary embolism
Reduced cognition
Irregular periods
Hot flashes
Flushing Nitrates
Headache
Light-headedness
Hypotension
Gastrointestinal upset Nitrofurantoin
Pulmonary fibrosis
Brown discolored urine
Peripheral neuropathy
Elevated liver enzymes
Hemolyticanemia
Anemia Thiazolidinediones
Dizziness, headache
Edema
Bladder cancer
Bone fractures
Hepatotoxicity
Gastrointestinal upset Valproate
Tremor, ataxia, behavioral effects
Increased liver enzymes
Thrombocytopenia
Hair loss
Pancreatitis
Vision disturbances Itraconazole
Heart failure
Skin rash
Hepatotoxicity
Thrombocytopenia Linezolid
Peripheral neuropathy
Serotonin syndrome
Metallic-like taste Metronidazole
Seizures
Thrombophlebitis (IV use)
Dark urine
Peripheral / optic neuropathy
Encephalopathy (high doses)
Disulfiram-reaction (with alcohol)
Dehydration Loop diuretics
Hypotension
Low electrolyte state
Hearing loss / tinnitus (high doses)
Kidney failure (w/ NSAID + ACE inhibitor)
Hyperuricemia
Gynecomastia Aldosterone
Hyperkalemia antagonists
Skin rash, sometimes SJS/TEN Allopurinol
Hypersensitivity reaction
Bone marrow suppression
Rhabdomyolysis Colchicine
Bone marrow suppression
Gastrointestinal upset