Sie sind auf Seite 1von 8

ORIGINAL ARTICLE

CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

Coronary Heart Disease in Ethnically Diverse Women:


Risk Perception and Communication

ALLISON H. CHRISTIAN, EDD; HEIDI Y. MOCHARI, MPH, RD; AND LORI J. MOSCA, MD, PHD

OBJECTIVES: To assess perceived vs calculated risk of coronary nity to screen women for CHD risk factors and to inform
heart disease (CHD), preferred methods of communicating risk,
and the effect of brief educational intervention to improve accu-
them of their personal risk of CHD. This population is a
rate perceptions of personal risk. desirable target for intervention because women who un-
SUBJECTS AND METHODS: Of 1858 women who underwent dergo routine mammography represent an aging population
screening mammography between April and September 2003 at in need of CHD risk factor evaluation and management.
the Columbia University Medical Center in New York, NY, we Perceptions of CHD risk appear to be positively corre-
assessed 125 women with no history of cardiovascular disease
who participated in a risk factor screening and education pro- lated with a desire to make risk-reducing behavioral
gram. Demographic variables were evaluated by interviewer-as- changes and with actual behavioral change.8,9 Perceptions
sisted standardized questionnaires. Absolute 10-year CHD risk of personal risk occupy a central role in theories of indi-
was calculated using the Framingham global risk assessment.
Perceived 10-year risk and preferred method of communicating vidual health behavior such as the Health Belief Model
risk were evaluated systematically. (HBM).10 The HBM suggests that perceptions of risk play a
RESULTS: Among 110 research participants who were eligible for critical role in a patient’s compliance with recommended
risk estimation, 59% had a 10-year risk of less than 10%. However, health behaviors. In a comprehensive review of the HBM
only half of those women accurately perceived their risk as low. and of cardiovascular risk factor reduction behaviors, per-
After a brief educational intervention, the women’s ability to
correctly categorize their personal CHD risk improved signifi- ceived vulnerability was found to be a significant contribu-
cantly. Preferred methods to communicate risk varied by level of tor in almost half the studies that assessed behaviors related
education and age. Older women (≥65 years) and those with a to CHD such as screening for hypertension.11
high school education or less were more likely to prefer simple
methods of having CHD risk communicated compared with their Effective primary prevention of CHD requires early
counterparts. detection of risk factors and communication of risk to
CONCLUSIONS: These data underscore the need to determine patients. National standards to stratify women on the basis
preferences for providing risk information and to test various of CHD risk and to guide preventive treatment are based on
formats for communicating CHD risk to improve awareness and
management of CHD risk factors, especially among women of
the Framingham global risk.12 Assessment and communi-
different age groups and education levels. cation of risk is necessary because it can assist patients in
Mayo Clin Proc. 2005;80(12):1593-1599 developing a more realistic perceived risk of CHD that, in
turn, may motivate them to initiate and maintain heart
BAC = breast arterial calcification; CHD = coronary heart disease; healthy behaviors at an appropriate target level.13 Optimally,
CI = confidence interval; HBM = Health Belief Model; OR = odds ratio a patient’s perceived risk of developing CHD should match
the patient’s actual calculated risk. However, there is lack of
agreement concerning the best approach for evaluating risk

C oronary heart disease (CHD), the leading cause of


death and premature disability among women in the
United States, disproportionately afflicts ethnic minority
or for communicating CHD risk to patients. The purposes of
this study were (1) to assess perceived risk vs calculated risk
on the basis of the Framingham global risk score, (2) to
groups including African American and Hispanic women.1-6 evaluate the effect of brief educational intervention to im-
Despite this fact, numerous studies have shown suboptimal prove knowledge of personal CHD risk, and (3) to determine
rates of CHD risk awareness among women. In a national preferred methods of communicating risk among women
survey of women with an oversampling of ethnic minorities who undergo routine screening mammography.
conducted by the American Heart Association, 13% of
women cited heart disease as their greatest health threat,
with less awareness and knowledge of risk factors noted From the Department of Medicine, Columbia University, New York, NY.
among ethnic minority women.7 Another important finding This study was supported by the Preventive Cardiology Program at NewYork-
of this survey was that women perceived breast cancer as Presbyterian Hospital.
their greatest health concern.7 Mammography has become Individual reprints of this article are not available. Address correspondence to
Lori J. Mosca, MD, PhD, Preventive Cardiology Program, NewYork-Presbyterian
a common and highly accepted screening tool for breast Hospital, 622 W 168th St, PH10-203B, New York, NY 10032 (e-mail: LJM10
cancer among women older than 40 years. The point of @columbia .edu).
service of mammography may represent a unique opportu- © 2005 Mayo Foundation for Medical Education and Research

Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com 1593

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

SUBJECTS AND METHODS rolled. Neither research participants nor controls were
recruited by mail. Of those who qualified as research
RESEARCH PARTICIPANTS AND DESIGN participants or controls, we spoke to 398 women and in-
This is a substudy of 125 women with no known history of formed them about the study. Inclusion criteria for participa-
cardiovascular disease who participated in a clinical trial tion were met by 354 of those women, and 125 were enrolled
conducted at the Columbia University Medical Center in subsequently in the study (35% acceptance rate). Primary
New York, NY, which evaluated CHD risk in those with reasons for nonparticipation included the following: (1) hav-
and without breast arterial calcification (BAC). This cross- ing a health care provider who monitored their CHD risk
sectional substudy with a 1-month follow-up included factors regularly (26%), (2) having no desire to participate in
women aged 35 years and older who were eligible for research (23%), (3) being too busy with work or family
participation in the trial provided they had undergone rou- responsibilities (18%), (4) living too far from the medical
tine screening mammography as an outpatient at the Co- center (11%), and (5) being too old and/or ill (10%).
lumbia University Radiology Clinic between April and Once enrolled, all research participants received stan-
September 2003 and either were found to have BAC on dardized CHD risk factor screening by a trained research
mammography or were serving as the next consecutive assistant and brief educational intervention. During the
age-matched control (within 5 years) to a woman who had educational intervention, which took approximately 1 hour,
BAC and was enrolled in this study. the research assistant provided information on the preva-
Potential research participants were identified through a lence of and the risk factors for CHD among women, the
systematic review of mammograms, and women were con- participant’s risk factor screening results, current risk fac-
tacted by telephone within 1 year of undergoing mammogra- tor goals, and methods to decrease the risk of developing
phy. Research participants agreed to participate in a 1-month CHD. At 1 month, all research participants were contacted
study that included a hospital-based CHD risk factor screen- via telephone or mail (per their preference) to complete a
ing and brief educational intervention plus a follow-up tele- questionnaire that assessed change in knowledge and
phone survey. A trained research assistant conducted all base- awareness of CHD and its risk factors, risk factor status,
line screenings and 1-month follow-up surveys. Permission medical history, level of perceived risk, and preferred
from the research participant’s physician was not required methods for having risk communicated.
for participation. Inclusion criteria included the ability to
give written informed consent, speak English or Spanish, DEMOGRAPHICS
and complete a 1-month follow-up questionnaire. Research Demographic variables were evaluated at baseline through
participants were excluded if they had a history of cardiovas- self-report by use of standardized interviewer-assisted
cular disease including myocardial infarction, coronary questions.
artery bypass grafting, angioplasty, stent, angina, stroke,
carotid artery disease, peripheral arterial disease, or abdomi- CARDIOVASCULAR RISK FACTORS
nal aortic aneurysm or if they were disoriented to person, A trained research assistant measured traditional CHD risk
place, or time. The Institutional Review Board at Columbia factors at baseline with use of standardized procedures.
University Medical Center approved the study, and all sub- Blood pressure was assessed by manual aneroid sphygmo-
jects gave written informed consent. manometer by using standard National Institutes of Health
Of the 1858 women who underwent routine screening Joint National Committee 7 guidelines.14 Lipids, lipopro-
mammography between April and September 2003 at the teins, and blood glucose levels were obtained by using a
Columbia University Radiology Clinic, we attempted to lancet to obtain a drop of blood from the participant’s
reach 1042 by telephone by using an age-matching sam- fingertip. The blood measurements were analyzed by
pling procedure. Among those who underwent routine fingerstick methods by using Cholestech technology
mammography during the specified period, women with (Cholestech Corp, Hayward, Calif), which is commonly
BAC were contacted by telephone first. Once a woman was used in screenings programs.15 Height was measured by a
enrolled in the study, a control was identified by selecting precision wall-mounted standardized-height rod. Weight
the next consecutive woman without BAC from the same was obtained by a standard physician’s scale with patients
list of women matched to the research participant by age in light clothing and without shoes. Body mass index was
within 5 years. The control also was contacted by tele- calculated directly by the standard formula: Weight (kg)/
phone. If the woman without BAC was interested in partici- [Height (m)]2. Waist circumference was measured under
pating, she was enrolled and served as the age-matched clothing using the guidelines provided in the Third National
control. If she did not want to participate, the same age- Health and Nutrition Examination Survey (NHANES III)
matching procedure was followed until a control was en- protocol.16

1594 Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

Other traditional risk factors for CHD including family STATISTICAL ANALYSES
history of premature CHD (age <65 years in women, <55 Demographic variables included race (white or ethnic
years in men), diabetes mellitus, and smoking were evalu- minority [African American, Hispanic, other]), age (<65 or
ated via self-report using standardized interviewer-assisted ≥65 years), education (≤high school or >high school edu-
questionnaires. cation), total annual household income (<$20,000 or
The Framingham global risk score was calculated with ≥$20,000), and marital status (married or unmarried). Cut
use of a National Heart, Lung, and Blood Institute work- points for age and education level were chosen on the
sheet and standard measurements of traditional risk factors basis of sample means. Descriptive statistics (frequencies,
including total cholesterol, smoking status, high-density li- means, SDs, percentages) were carried out for demo-
poprotein, and systolic blood pressure (Appendix 1).17-19 graphic data. Prevalences of absolute risk, perceived risk,
This global risk estimate was used to determine each and preferred methods of communicating risk are pre-
participant’s absolute risk, defined as the probability of hav- sented as counts and percentages. Continuous variables are
ing a heart attack or dying of CHD during a 10-year period. presented as mean ± SD after checking for normality.
In accordance with recent guidelines, if a research partici- Within-group changes in accurate risk perception from
pant reported a family history of premature CHD, she was preintervention to postintervention, from prescreening to 1
classified at intermediate risk of CHD (10%-20%).12 Also, month, and from postscreening to 1 month were evaluated
because diabetes mellitus is considered a cardiovascular dis- by using the McNemar test for paired data. Univariate
ease risk equivalent, any research participant with self- predictors of accurate perceived risk and preferred risk
reported diabetes mellitus and/or a fasting plasma glucose communication methods were evaluated using the χ2 test.
level of 126 mg/dL or greater was considered as having Logistic regression was used to evaluate the independence
diabetes and thus categorized as high risk (>20%).12,17 of demographic factors to predict accurate perceived risk
and preferred methods of communicating risk. All
PERCEIVED RISK univariate predictors at P<.10 were included in the models.
Various likelihood scales have been used to assess perceived Age, as a predictor of accurate perceived risk and preferred
risk of disease among patient populations including percent- risk communication method, was examined as both a cat-
age scales, 5- or 7-point verbally labeled scales, and visual/ egorical variable by use of the χ2 test and as a continuous
graphic scales. However, there is no indication that any scale variable by use of the Student t test. Statistical significance
is consistently superior to another for measuring risk percep- was accepted at the 95% confidence interval (CI) or P<.05.
tions. Percentage scales are recommended when comparing The SAS analytic program, version 8e, (SAS Institute Inc,
risk perceptions with actual statistics.20 Therefore, perceived Cary, NC) was used for all analyses.
risk was evaluated in this study by asking research partici-
pants, “In the next 10 years, what do you think your chances
RESULTS
are of having a heart attack or dying of heart disease com-
pared to a woman of similar age as you?” Perceived 10-year The baseline characteristics of the study population are
risk was measured before the baseline screening, imme- presented in Table 1. Research participants ranged between
diately after the educational intervention, and at the 1-month ages 38 and 86 years with a mean age of 62.9 (±SD 10.9).
follow-up by using this question. Response options included No significant difference in age existed between white and
low (less than 10%), moderate (between 10% and 20%), and ethnic minority research participants. Among participants,
high (more than 20%). 56 (44.8%) were Hispanic, 37 (29.6%) were white, 24
(19.2%) were African American, and 8 (6.4%) classified
COMMUNICATION OF RISK themselves as “other.” Thirty-six participants (28.8%)
The preferred method of communicating risk was evalu- were married. Among participants, 60 (48.0%) had more
ated after the baseline screening and intervention and at 1 than a high school education, 36 (28.8%) had less than a
month by a standardized interviewer-assisted questionnaire. high school education, and 29 (23.2%) had a high school
Research participants were asked to identify their single diploma (or equivalent). Fifty-nine (54.6%) of the 108
preferred method of having CHD risk communicated from women who responded to an income level question re-
the following list: (1) relative risk, (2) absolute risk, (3) ported being of low-income status with a total annual
cardiovascular age equivalent, (4) number of traditional risk household income of less than $20,000. Most research
factors, (5) risk categorized as low/moderate/high, (6) other, participants (90 of 124 [73%]) were unemployed, with
and (7) do not know. The research assistant discussed each 48 (38.7%) retired, 15 (12.1%) on medical disability,
method of communicating risk in detail with the research 17 (13.7%) homemakers, 7 (5.7%) out of work, 2 (1.6%) in
participant by using a standardized script (Appendix 2). school, and 1 (0.8%) other. Most (98; 78.4%) had Medicaid

Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com 1595

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

TABLE 1. Characteristics of 125 Women Who Underwent risk, 22 (20%) had between a 10% and 20% 10-year risk,
Routine Screening Mammography*
and 23 (21%) had a greater than 20% 10-year risk of CHD.
Ethnic Paradoxically, only 52% (29 of 56 responders) of those
Overall White minority
Demographics (n=125) (n=37) (n=88) calculated to be at low risk correctly perceived their risk of
CHD as low (<10%) at baseline. Immediately after the
Mean ± SD age (y) 62.94±11 65.46±12 61.89±10
White 37 (30.0) NA NA educational intervention there was a significant increase in
>High school education† 60 (48.0) 31 (83.8) 29 (33.0) the proportion of women who correctly categorized their
Unemployed‡ 90 (72.6) 23 (62.2) 67 (77.0) risk as low (<10%) (67% [36 of 54 responders] vs 52%;
Married§ 36 (28.8) 16 (43.2) 20 (22.7)
Low income⁄⁄ 59 (54.6) 7 (24.1) 52 (65.8) P=.02). However, the improvement in accurate risk percep-
tion deteriorated after 1 month with only 28 of the 54
*All data presented as number (%). Significant difference found between
white and ethnic minority research participants. NA = not applicable. female responders (52%) correctly perceiving their risk as
†P<.001. low. Among the moderate and high-risk women (≥10%)
‡Of 124 women overall and 87 ethnic minority women who responded. there was a gradual decline in the number of women who
§P=.02.
⁄⁄Of 108 women who responded. accurately perceived their risk as moderate or high from
prescreening (71% [25 of the 35 responders]) to post-
screening (68% [23 of the 34 responders]) to 1-month
or Medicare as their primary form of health insurance. follow-up (64% [25 of the 39 responders]). Change in
Significant differences existed between white and ethnic accurate risk perception over time is presented in Figure 1.
minority research participants in education level (P<.001), Among women at low risk, no predictors of accurate
marital status (P=.02), and income level (P<.001). risk perception were found at prescreening, postscreening,
Of the 125 women who participated in the baseline or 1-month follow-up when evaluating demographic fac-
screening, 111 (89%) completed the 1-month follow-up tors including age, education level, ethnic minority status,
survey. Primary reasons for incomplete follow-up included and income. Among moderate- or high-risk women, no
an inability to reach the research participant (via telephone predictors of accurate risk perception were found at
and mail) or the participant reporting to be too busy. prescreening or postscreening. However, among moderate-
Among the 110 research participants eligible for or high-risk women at 1-month follow-up, in a multiple
Framingham global risk estimation (women aged 20-79 linear regression model controlling for confounders, age
years, inclusive), 65 (59%) had a less than 10% 10-year (≥65 years) was associated with accurate risk perception
(odds ratio [OR], 4.51; 95% CI, 0.97-21.00). No other
predictors of accurate risk perception were found when
100 analyzing family history of premature CHD, previous CHD
Prescreening
90 Postscreening risk factor (ie, blood pressure, cholesterol) screenings, hav-
1-Month follow-up
80 ing a basic knowledge of CHD (ie, CHD is the leading
70
cause of death for women in the nation), and feeling well
Percent correct

informed about CHD in women.


60
Overall, research participants preferred the simpler
50 methods of presenting CHD risk information. Among the
40 106 women who provided data on preferred methods of
30 risk communication, 36 (34%) preferred CHD risk ex-
20
pressed as number of risk factors, 29 (27%) preferred their
risk categorized as high, moderate, or low, 21 (20%) pre-
10
ferred absolute risk (ie, Framingham 10-year risk score),
0
Low or <10% risk Intermediate/high or ≥10% risk
6 (6%) preferred receiving a cardiovascular age equivalent,
(n=65) (n=55) 5 (5%) preferred other ways (ie, combined methods),
Calculated absolute 10-year risk 7 (6%) responded that they did not know, and only 2 (2%)
preferred relative risk. In a univariate model, at baseline,
women younger than 65 years were more likely to prefer
FIGURE 1. Prevalence and change in accurate risk perception.
Calculated absolute risk was based on results of the woman’s risk information expressed through detailed methods (rela-
Framingham global risk estimate. Percent correct includes women tive risk, absolute risk, or cardiovascular age equivalent)
who correctly assessed their personal risk of heart disease com- than as number of risk factors and risk factor categories
pared with their true calculated risk. Significant change was from
prescreening to postscreening (P=.02). Analysis was limited to 110 compared with women age 65 years or older (OR, 2.44;
research participants between ages 20 and 79 years, inclusive. 95% CI, 0.97-6.15). When examining age as a continuous

1596 Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

variable, younger women were also more likely to prefer sized age as the driving factor in the Framingham global risk
the more detailed methods (P=.04). A trend remained for assessment. However, our study identified no additional
age as a predictor of preferred method of communicating predictors of perceived risk found in previous trials such as
risk (OR, 2.40; 95% CI, 0.93-6.17) in a multivariate family history of CHD and actual calculated absolute risk.21
analysis controlling for potential confounders (ethnicity, This study found that a simple yet systematic CHD risk
age, education). This multivariate logistic regression factor screening and educational intervention for women
model also revealed that women with a high school edu- undergoing routine mammography was sufficient to im-
cation or less were more likely to prefer simpler methods prove women’s ability to correctly categorize their per-
of having risk presented (number of risk factors and risk sonal risk. However, although immediate recall was good,
factor categories) than more detailed methods (relative this improvement deteriorated over time, suggesting that
risk, absolute risk, or cardiovascular age equivalent) com- reinforcement and educational follow-up may be necessary
pared with women with more than a high school educa- to sustain improvements in knowledge and awareness. The
tion (OR, 2.80; 95% CI, 0.98-7.99). Ethnic minority sta- long-term effectiveness of a brief screening and educa-
tus, income, marital status, family history of premature tional intervention on women’s accurate perceptions of
cardiovascular disease, and calculated absolute risk were personal risk cannot be determined from this study, and
not statistically significant predictors of preferred risk further evaluation is required.
communication methods in this multivariate analysis. An important finding of this study was that most women
There was no relationship found between preferred (61%) preferred simpler methods of having risk communi-
method of having risk communicated and accurate risk cated. Our findings correspond with those of Fortin et al,24
perception before or after intervention. who found that women preferred simpler formats for pre-
senting health risk information (ie, bar graph) and data
framed in absolute rather than relative terms. In the Fortin
DISCUSSION
et al descriptive pilot study, focus group discussions with
This study documented that only about one half of women 40 women (mean age, 51 years; 50% ethnic minority) were
at low risk and two thirds of women at moderate or high conducted to identify preferred methods of having CHD,
risk of CHD accurately perceived their risk level. Most hip fracture, and breast cancer risk communicated. The
women at low risk overestimated their risk level in this women interviewed preferred simple bar graphs over line
study. Importantly, we found that young women calculated graphs, thermometer graphs, 100 representative faces, and
to be at moderate or high risk underestimated their risk of survival curves. In addition, they reported a preference for
CHD, suggesting that education and prevention messages absolute risk over relative risk, concurring with the find-
need to be targeted to this subpopulation at increased risk ings of our study. Preference for having risk communicated
of poor clinical outcomes and future CHD events. varied in our study by age, ethnicity, and education level.
Our findings concur with those of Frijling et al,21 who However, these potential predictors need to be further
found that participants at moderate to high risk of cardio- evaluated in clinical trials with larger sample sizes.
vascular disease (n=1194) overestimated their actual 10- A limitation of the Framingham global risk assessment
year risk by more than 20%, with men having higher accu- is that calculated absolute risk may be inaccurate in ethnic/
racy of perceived absolute risk. These findings may explain racial minorities. Statistical models used to predict per-
why our all-female sample showed inaccurate perceptions sonal risk of death from CHD have been based on studies
of personal CHD risk. However, it is important to note that among white populations such as the Framingham Heart
the Frijling et al sample primarily consisted of white pa- Study.18,19 Attempts to assess the generalizability of the
tients, and 42% were men.21 Therefore, although our find- prediction model have yielded inconsistent results, in part
ings enhance existing data on risk perception, further data because of the limited cohort data available for women and
are needed to evaluate risk perceptions among women and ethnic minority groups.25-27 A recent study provided evidence
ethnic minorities. that although sex-specific Framingham CHD risk prediction
Previous literature also suggests that demographic vari- functions perform well among white and African American
ables such as age, sex, and education are related to an in- patients, recalibration may be necessary for other ethnic
creased perceived risk for certain diseases such as heart groups, based on the varying prevalence of risk factors and
attack.21-23 In this study, older age was found to be a signifi- underlying rates of CHD events.28 Therefore, the use of
cant predictor of accurate high-risk perception at 1-month Framingham prediction scores in this study, with the high
follow-up. This may suggest that the educational interven- participation rate of Hispanic women, may have led to inac-
tion was more effective among older women. This is not curate estimations of risk. Nonetheless, the Framingham
unexpected because the educational intervention empha- score is the national standard to guide the intensity of CHD

Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com 1597

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

preventive interventions regardless of ethnic status. This APPENDIX 1. Framingham Global Risk Estimate of
research suggests that although use of the Framingham glo- 10-Year Risk for Women*
bal risk assessment is recommended to modify the intensity Risk factor
of risk-reduction efforts, health care providers should use
Age (y) Points
caution in using it to motivate patients to adhere to risk- 20-34 –7
reduction therapies as previously suggested.13 35-39 –3
Major strengths of this study include greater than 50% 40-44 0
45-49 3
representation by ethnic minorities in the sample and high 50-54 6
follow-up (89%). However, the study has several limita- 55-59 8
tions. Its nonrandom sample primarily comprised low-risk 60-64 10
women. As such, results may not generalize to other popula- 65-69 12
70-74 14
tions, and further evaluation of preferences for having CHD 75-79 16
risk communicated among intermediate-risk and high-risk
women is needed. In addition, the absence of a control group Total
cholesterol (mg/dL) Points for age range (y)
makes it impossible to compare the results of those who
20-39 40-49 50-59 60-69 70-79
received the risk factor screening and intervention with a <160 0 0 0 0 0
representative group of women who did not. The validity of 160-199 4 3 2 1 1
the instrument used to assess methods of communicating 200-239 8 6 4 2 1
risk is unknown; therefore, further research is needed to 240-279 11 8 5 3 2
>280 13 10 7 4 2
determine the most valid, timely, and efficient method of
assessing preferred methods of communicating CHD risk, Points for age range (y)
particularly among samples of women and diverse ethnic
20-39 40-49 50-59 60-69 70-79
groups. Multiple statistical comparisons were made without Nonsmoker 0 0 0 0 0
adjustment. Nevertheless, this was an exploratory analysis, Smoker 9 7 4 2 1
and findings should be considered for future analyses rather
than as definitive associations. Finally, we were unable to HDL (mg/dL) Points
≥60 –1
correlate behavior change associated with change in risk 50-59 0
perception; thus, future studies should evaluate whether ac- 40-49 1
curate perception of personal risk leads to improved clinical <40 2
outcomes.
Systolic BP (mm Hg) If untreated If treated
<120 0 0
CONCLUSIONS 120-129 1 3
130-139 2 4
A substantial proportion of women in this study did not 140-159 3 5
>160 4 6
accurately perceive their CHD risk level, and a brief educa-
tional intervention significantly improved short-term risk Point total 10-year risk (%)
perception. Furthermore, our results suggest that methods to <9 <1
communicate personal coronary risk should be tailored to a 9 1
participant’s age and education level on the basis of pre- 10 1
11 1
ferred methods reported by women in this study, although 12 1
individualization of information by using the method that 13 2
most suits each patient is optimal. Various formats for com- 14 2
municating CHD risk should be tested, especially among 15 3
16 4
women of different ages and education levels, to determine 17 5
whether providing a preferred method results in improved 18 6
awareness and management of risk factors. 19 8
20 11
21 14
We thank the Cholestech Corporation of Hayward, Calif, for 22 17
donating the cholesterol measurement supplies. We acknowledge 23 22
24 27
Drs Suzanne Smith and Hongju Son for their assistance in review-
>25 >30
ing mammography films, as well as Dr Jhansi Reddy for her
assistance with data collection. *BP = blood pressure; HDL = high-density lipoprotein.

1598 Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.
CORONARY HEART DISEASE IN ETHNICALLY DIVERSE WOMEN

APPENDIX 2. Script for Assessing Preferred Method of Having 8. Winkleby MA, Flora JA, Kraemer HC. A community-based heart dis-
CHD Risk Communicated ease intervention: predictors of change. Am J Public Health. 1994;84:767-772.
9. Silagy C, Muir J, Coulter A, Thorogood M, Roe L. Cardiovascular risk
There are different ways that health care professionals can communicate and attitudes to lifestyle: what do patients think? BMJ. 1993;306:1657-1660.
your risk of heart disease to you. I’m going to go through some of those 10. Rosenstock IM. The health belief model and preventive health behavior.
different ways. After I get through explaining them, please let me know Health Educ Monogr. 1974;2:354-386.
how you would you like your heart disease risk to be described to you. 11. Janz NK. The Health Belief Model in understanding cardiovascular risk
Please choose only one way, state “other” if you have a different way factor reduction behaviors. Cardiovasc Nurs. 1988;24:39-41.
you’d like, or “don’t know” if you cannot choose between the methods 12. Mosca L, Appel LJ, Benjamin EJ, et al, American Heart Association.
discussed or you are unsure. If you don’t understand a specific method or Evidence-based guidelines for cardiovascular disease prevention in women.
the question, in general, please feel free to stop me and I will explain Circulation. 2004;109:672-693.
again. 13. Grundy SM, Pasternak R, Greenland P, Smith S Jr, Fuster V. Assessment
of cardiovascular risk by use of multiple-risk-factor assessment equations: a
(1) Relative risk is a measure of how much a particular risk factor (say
statement for healthcare professionals from the American Heart Association and
cigarette smoking) influences the risk of a specified outcome (say, devel- the American College of Cardiology. J Am Coll Cardiol. 1999;34:1348-1359.
oping CHD by age 65). 14. Chobanian AV, Bakris GL, Black HR, et al, National Heart, Lung, and
(2) Absolute risk is the observed or calculated probability of develop- Blood Institute Joint National Committee on Prevention, Detection, Evalua-
ing CHD. This is what was given to you today, the Framingham global tion, and Treatment of High Blood Pressure, National High Blood Pressure
risk score we reviewed. Education Program Coordinating Committee. The Seventh Report of the Joint
(3) Cardiovascular age equivalent is the age you become when you National Committee on Prevention, Detection, Evaluation, and Treatment of
add your CHD risk factors to your real age. For example, if you are 50 High Blood Pressure: the JNC 7 report [published correction appears in JAMA.
years old and your low-density lipoprotein (LDL) cholesterol level is 2003;290:197]. JAMA. 2003;289:2560-2572.
severely elevated and you smoke, your cardiovascular age equivalent may 15. Cobbaert C, Boerma GJ, Lindemans J. Evaluation of the Cholestech
be 62 years old. L.D.X. desktop analyser for cholesterol, HDL-cholesterol, and triacylglycerols
(4) Number of traditional risk factors would simply be the number of in heparinized venous blood. Eur J Clin Chem Clin Biochem. 1994;32:391-
traditional CHD risk factors, modifiable and non-modifiable, you have. 394.
For instance, if you were a smoker and were a woman older than 65 years 16. National Health And Nutrition Examination Survey III: Reference
of age, you would have 2 risk factors. Manuals and Report—1996. Hyattsville, MD: US Department of Health and
(5) Risk categories mean that you will be told if you are at high (>20% Human Services, Center for Disease Control and Prevention, National Center
chance of developing CHD or having a heart attack in the next 10 years), for Health Statistics. Available at: www.cdc.gov/nchs. Accessed December
2004.
moderate (between 10% and 20% chance of developing CHD or having a
17. Third Report of the National Cholesterol Education Program (NCEP)
heart attack in the next 10 years), or low (<10% chance of developing Expert Panel on Detection, Evaluation, and Treatment of High Blood Choles-
CHD or having a heart attack in the next 10 years) risk. terol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;
(6) Other means that you would prefer to have your risk of CHD 106:3143-3421.
explained to you in another way (if so, what) or through a combination of 18. Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H,
the methods offered above. Kannel WB. Prediction of coronary heart disease using risk factor categories.
(7) Do not know means that you are unsure of how you prefer to have Circulation. 1998;97:1837-1847.
your CHD risk communicated to you. 19. Kannel WB, McGee D, Gordon T. A general cardiovascular risk profile:
the Framingham Study. Am J Cardiol. 1976;38:46-51.
20. Weinstein ND, Diefenbach MA. Percentage and verbal category mea-
sures of risk likelihood. Health Educ Res. 1997;12:139-141.
21. Frijling BD, Lobo CM, Keus IM, et al. Perceptions of cardiovascular risk
REFERENCES among patients with hypertension or diabetes. Patient Educ Couns. 2004;52:
1. American Heart Association. Heart Disease and Stroke Statistics—2005 47-53.
Update. Available at: www.americanheart.org. Accessed December 2004. 22. Legato MJ, Padus E, Slaughter E. Women’s perceptions of their general
2. Winkleby MA, Robinson TN, Sundquist J, Kraemer HC. Ethnic varia- health, with special reference to their risk of coronary artery disease: results of
tion in cardiovascular disease risk factors among children and young adults: a national telephone survey. J Womens Health. 1997;6:189-198.
findings from the Third National Health and Nutrition Examination Survey, 23. Pilote L, Hlatky MA. Attitudes of women toward hormone therapy and
1988-1994. JAMA. 1999;281:1006-1013. prevention of heart disease [editorial]. Am Heart J. 1995;129:1237-1238.
3. Harris MI, Flegal KM, Cowie CC, et al. Prevalence of diabetes, impaired 24. Fortin JM, Hirota LK, Bond BE, O’Connor AM, Col NF. Identifying
fasting glucose, and impaired glucose tolerance in U.S. adults: the Third patient preferences for communicating risk estimates: a descriptive pilot study.
National Health and Nutrition Examination Survey, 1988-1994. Diabetes BMC Med Inform Decis Mak. 2001;1:2-12.
Care. 1998;21:518-524. 25. Tyroler HA, Knowles MG, Wing SB, et al. Ischemic heart disease risk
4. King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: factors and twenty-year mortality in middle-age Evans County black males.
prevalence, numerical estimates, and projections. Diabetes Care. 1998;21: Am Heart J. 1984;108(3, pt 2):738-746.
1414-1431. 26. Keil JE, Sutherland SE, Knapp RG, Lackland DT, Gazes PC, Tyroler
5. Gillum RF. Secular trends in stroke mortality in African Americans: the role HA. Mortality rates and risk factors for coronary heart disease in black as
of urbanization, diabetes and obesity. Neuroepidemiology. 1997;16:180-184. compared with white men and women. N Engl J Med. 1993;329:73-78.
6. Greenlund KJ, Giles WH, Keenan NL, Croft JB, Casper ML, Matson- 27. Cooper RS, Ford E. Comparability of risk factors for coronary heart
Koffman D. Prevalence of multiple cardiovascular disease risk factors among disease among blacks and whites in the NHANES-I Epidemiologic Follow-up
women in the United States, 1992 and 1995: the Behavioral Risk Factor Study. Ann Epidemiol. 1992;2:637-645.
Surveillance System. J Womens Health. 1998;7:1125-1133. 28. D’Agostino RB Sr, Grundy S, Sullivan LM, Wilson P, CHD Risk Predic-
7. Mosca L, Ferris A, Fabunmi R, Robertson RM, American Heart Associa- tion Group. Validation of the Framingham coronary heart disease prediction
tion. Tracking women’s awareness of heart disease: an American Heart Asso- scores: results of a multiple ethnic groups investigation. JAMA. 2001;286:180-
ciation national study. Circulation. 2004;109:573-579. 187.

Mayo Clin Proc. • December 2005;80(12):1593-1599 • www.mayoclinicproceedings.com 1599

For personal use. Mass reproduce only with permission from Mayo Clinic Proceedings.

Das könnte Ihnen auch gefallen