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R E L I A B L E I N F O R M A T I O N F O R A H E A L T H I E R L I F E
VOLUME 23 NUMBER 9 SEPTEMBER 2005
Coming in October
OVARIAN CANCER
Recognize the early warning signs.
BEANS
Make them diet regulars.
ADULT ACNE
Troublesome, but treatable.
ERYTHROPOIETIN
Treating severe anemia.
Stroke occurs when the supply of blood that normally nourishes the brain is reduced. Stroke
affects brain cells that send signals controlling almost every function in the body, including
those listed in this illustration. In addition, stroke on the right side of the brain often affects
functions on the left side of the body, while a stroke on the left side of the brain often affects
functions on the right side of the body.
2 M AYO C L I N I C H E A LT H L E T T E R
SEPTEMBER 2005
leaks into the brain or into tissues understanding what you read or learning to self-propel a wheelchair,
surrounding the brain. what people say. balance skills, and maximizing the
Stroke affects brain cells that ■ Psychological — Stroke can range of motion in your joints.
send signals controlling almost every affect you by damaging an area of Rehabilitation may also involve
function in the body. When brain your brain that’s involved in pro- relearning self-care skills — includ-
tissue is damaged, it can have far- ducing emotions. You may feel help- ing eating, grooming, bathing and
ranging effects, including: less, frustrated and uninterested in dressing — or learning to adapt how
■ Physical — Paralysis, stiffness, activities you once enjoyed. You may you perform these tasks to com-
weakness, a loss of feeling or lack cry or laugh more easily or have pensate for disability. Addressing
of coordination may affect your face, sudden mood swings for no appar- cognitive skills, including memory
an arm or a leg, or an entire side ent reason. Depression, grief, irri- and problem solving, and commu-
of your body. You also may have bal- tability and fatigue sometimes occur. nication and social skills also are
ance problems, visual problems, important parts of rehabilitation (see
including partial blindness in one What’s involved “Speech therapy” in our July 2004
or both eyes, or trouble speaking or The purpose of rehabilitation is issue). You may also learn how to
swallowing. to reach the highest possible level reorganize your living space to make
■ Cognitive — The way in which of independence. What you do in it safer and more accessible.
you think, remember, interact with rehabilitation depends on what skills Because numerous impairments
others or perceive the world around you need to become independent. may be involved, rehabilitation is
you may be affected. Perceptual A major part of rehabilitation is often facilitated by a diverse team, which
changes may make it hard for you physical training and therapy. This may include doctors specializing in
to understand what you feel, see or may involve training with mobility
hear. You may also have difficulty skills, such as relearning to walk or MAYO CLINIC HEALTH LETTER
Managing Editor Medical Editor
Aleta Capelle Robert Sheeler, M.D.
The road to recovery after stroke Associate Editors Associate Medical Editor
Carol Gunderson David Williams, M.D.
The outlook for stroke reha- ■ Its intensity and frequen- Jennifer Jacobson
Editorial Research
Joey Keillor
bilitation is better today than cy — Studies suggest that Deirdre Herman
Medical Illustration Shelly Hewlett
ever before. After a stroke, greater intensity and frequency Michael King
Proofreading
some people experience a of therapy improves functional Customer Service Miranda Attlesey
Manager Donna Hanson
complete or nearly complete outcomes. Even if rehabilitation Ann Allen
Administrative Assistant
recovery. Still, approximately sessions are scheduled only a Jill Thompson-Riese
half of stroke survivors will be few times a week, therapeutic EDITORIAL BOARD
left with some kind of perma- exercises should be done on a Shreyasee Amin, M.D., Rheumatology; Amindra
nent disability. daily basis. Arora, M.D., Gastroenterology and Hepatology; Brent
Bauer, M.D., Internal Medicine; Julie Bjoraker, M.D.,
The success of rehabilitation ■ Your outlook and attitude Internal Medicine; Diane Dahm, M.D., Orthopedics;
depends on many factors, — Motivation and a positive Timothy Daley, M.D., Internal Medicine; Mark Davis,
M.D., Dermatology; Bobbie Gostout, M.D., Gyneco-
including: attitude are key to obtaining an logic Surgery; Timothy Hobday, M.D., Oncology;
Todd Johnson, Pharm.D., Pharmacy; Frank Kennedy,
■ Its timing — The earlier optimal level of recovery. Reha- M.D., Endocrinology and Metabolism; Suzanne
rehabilitation begins, the more bilitation requires a willingness Norby, M.D., Nephrology; Steve Ommen, M.D.,
Cardiology; Robert Sheeler, M.D., Family Medicine;
likely you are to regain lost to work hard. Phillip Sheridan, D.D.S., Periodontics; Peter Southorn,
M.D., Anesthesiology; David Williams, M.D.,
abilities and skills. ■ The cooperation of Pulmonary and Critical Care Medicine; Mark
■ The extent of brain injury friends and family — Com- Williams, M.D., Psychiatry; Aleta Capelle, Health
Information. Ex-officio: Carol Gunderson, Jennifer
— People with milder injuries panionship and emotional Jacobson and Joey Keillor.
are likely to benefit the most. support are essential to reha-
Mayo Clinic Health Letter (ISSN 0741-6245) is published
But even with slight improve- bilitation. Caregivers also play monthly by Mayo Foundation for Medical Education and
ment, rehabilitation can mean an important role in assisting Research, a subsidiary of Mayo Foundation, 200 First St.
S.W., Rochester, MN 55905. Subscription price is $27
the difference between return- with rehabilitation exercises a year, which includes a cumulative index published in
December. Periodicals postage paid at Rochester, Minn.,
ing to your home or staying in a and therapies and helping you and at additional mailing offices. POSTMASTER: Send
care facility. maintain improvement. address changes to Mayo Clinic Health Letter,
Subscription Services, P.O. Box 9302, Big Sandy, TX
75755-9302.
M AYO C L I N I C H E A LT H L E T T E R 3
SEPTEMBER 2005
Joint infections
News and our views
Early and aggressive
Annual flu vaccination improves odds for older adults treatment is vital
Receiving a flu vaccination can significantly reduce hospitaliza-
tions and deaths among high-risk older adults. However, the pro- You’ve never experienced pain like
tection provided by a flu vaccine is good for only a year due to chang- this before. Over the course of an
ing influenza strains. An annual revaccination is crucial in order to hour — and for no apparent reason
continue receiving these benefits. — the slightest movement of your
A study in the Nov. 3, 2004, Journal of the American Medical knee causes excruciating pain. The
Association looked at the effects of flu vaccination among older adults. skin looks red and is warm to the
Researchers found that the first flu vaccination reduced the risk of touch. Your doctor says it looks like
death in men and women age 65 and older by 10 percent. Those who an acute infection has settled in your
were revaccinated in following years reduced their risk of death by knee joint.
an additional 15 percent to 28 percent. Those whose vaccine series As surprising as it may seem,
was interrupted experienced a strong increase in mortality risk. joints are subject to infection. Prompt
However, restarting vaccination after an interruption led to a risk treatment for bacterial infections of
reduction similar to that found following revaccination. Overall, one a joint typically involves surgery and
death was prevented for every 302 vaccinations. Other studies have antibiotics. This is done in an effort
found an average of 50 percent reduction in deaths among older adults to stop the infection before it severe-
who receive a flu vaccine. ly damages the affected joint. Joint
Mayo Clinic doctors recommend an annual flu shot for all adults infections from other types of germs
over 50, for those with medical conditions such as heart disease may require antibiotics alone or —
and diabetes, and for all others at high risk of complications. ❒ in the case of some viruses — treat-
ment may not be required.
Rethinking early bone-loss treatment
A medication typically used to treat osteoporosis in postmenopausal Behind the infection
women may also help prevent fractures of the spine (vertebral frac- The cause of infections in joints
tures) in women with early bone loss (osteopenia). can be bacteria, viruses, fungi and
Osteopenia is a condition in which your bone density lies some- other germs. These organisms can
where between normal levels and levels that indicate the presence of reach a joint in a couple of ways.
the bone-thinning disease osteoporosis, but you haven’t yet experi- One way occurs when infection
enced complications such as fractures. Unlike osteoporosis, first-line located elsewhere in your body —
therapy for osteopenia typically hasn’t included the use of prescrip- such as pneumonia in your lungs or
tion medications that prevent bone loss. a urinary tract infection —is trans-
But a review of data from a multicenter study done in the 1990s ported through your blood and set-
found that postmenopausal women with osteopenia who took the bis- tles in a joint. Another means of
phosphonate drug alendronate (Fosamax) experienced a 60 percent introducing infection to a joint is
reduction in vertebral fractures. The findings, published in the March through a direct injury.
2005 issue of Mayo Clinic Proceedings, also showed that alendronate’s A joint infection — referred to
benefit was measurable early on in the three years of treatment. as septic or infectious arthritis —
Mayo Clinic doctors say the findings suggest an expanded role for is most commonly caused by the
oral bisphosphonate drugs — such as alendronate — which prevent staphylococcus bacterium often car-
bone loss (resorption). Another drug in this class of medications — ried on the skin. Joint infections can
risedronate (Actonel) — has also proved helpful in managing early also be caused by other germs, such
bone loss. Mayo doctors say it’s too soon to conclude that all women as tuberculosis, the sexually trans-
with osteopenia should take bisphosphonate drugs. However, in all mitted bacterium gonorrhea and the
likelihood, it will be women with osteopenia who also have addi- germ that causes Lyme disease.
tional risk factors for bone loss that may benefit the most. ❒ Various factors may put you at
greater risk of developing a joint
M AYO C L I N I C H E A LT H L E T T E R 5
SEPTEMBER 2005
Second opinion
Questions and our answers totally disabling for others. Psoriasis
affects the life cycle of skin cells,
Q: I have an underactive thyroid resulting in the rapid accumulation
and take the thyroid drug levothy- of cells that form dry, red patches of
roxine. I also take a calcium sup- skin covered with silvery scales. The
plement to help prevent osteo- inflammation usually affects the el-
Seborrhea most commonly affects the scalp,
porosis. I’ve heard that I should take nose, eyebrows, area behind the ears and
bows, knees, trunk and scalp. Psor-
these two at different times of the the chest. iasis tends to flare periodically and
day. Is this true? then subside for a time, but it almost
always returns. Scalp psoriasis and
A: Yes it is. scalp seborrhea can be hard to dif-
In some people, taking a calci- ferentiate. Sometimes the diseases
um supplement has been shown to overlap. Fortunately, treatments for
interfere with the body’s ability to both are similar.
absorb levothyroxine (Levothroid, Psoriasis usually affects the elbows, knees, Like seborrhea, psoriasis is be-
Levoxyl, Synthroid), thus reducing
trunk and scalp. lieved to be an inherited disorder.
thyroid levels to below what the Although psoriasis can’t be cured,
the skin. It most commonly affects
body requires. However, this effect treatments are usually effective but
the scalp, nose, eyebrows, area be-
appears to occur only when the must be tailored to each person,
hind the ears and the chest.
medication and supplement are especially in more severe cases. In
Seborrhea tends to run in fami-
taken at the same time. mild cases, nonprescription soaps,
lies. In the scalp, it causes dandruff,
If you take a calcium supple- shampoos or ointments may suffice.
which can be associated with an
ment — as many people do for gen- Otherwise, prescription ointments,
itchy scalp. In infants, it may appear
eral osteoporosis prevention — Mayo prescription oral medications or
as crusty, scaly skin on the scalp
Clinic doctors say that the thyroid phototherapy may be necessary. ❒
called cradle cap.
drug and the supplement should be Treatment for seborrhea gener- Have a question or comment?
taken at least four hours apart so that ally can help keep it under control. We appreciate every letter sent to Second
your body can properly absorb your If dandruff is the problem, daily Opinion but cannot publish an answer to each
thyroid medication. It’s also best to shampooing and careful rinsing may question or respond to requests for consultation
take thyroid medications each morn- on individual medical conditions. Editorial
help. Your doctor may recommend comments can be directed to:
ing before eating. ❒ using a nonprescription medicat- Managing Editor, Mayo Clinic Health Letter,
ed shampoo containing ketocona- 200 First St. S.W., Rochester, MN 55905, or
Q: Please explain the difference zole, tar, zinc pyrithione, selenium send e-mail to HealthLetter@Mayo.edu
For information about Mayo Clinic services,
between seborrhea and psoriasis. sulfide or salicylic acid. Creams or you may telephone any of our three facilities:
solutions containing hydrocortisone Rochester, Minn., (507) 284-2511;
A: Seborrhea, also called seborrheic or ketoconazole cream may help Jacksonville, Fla., (904) 953-2000;
dermatitis, is a common, generally treat other affected areas. Scottsdale, Ariz., (480) 301-8000 or visit
www.MayoClinic.org
mild skin disorder. It’s characterized Psoriasis is also a common skin
by greasy scaling, itchiness and a disorder but ranges from being a Check out Mayo Clinic Health Information’s
somewhat reddened appearance of mild nuisance for some to being Web site, at www.MayoClinic.com