ABSTRACT PREVIEW

ABSTRACT INFORMATION
Abstract No. : AB-0177-ON
Submission for : Poster Presentation
Topic : Hematology-oncology
Keyword 1 : HRQoL
Keyword 2 : Children
Keyword 3 : Thalassemia
Other Keyword :
Abstract Category : Clinical audit, prospective survey or retrospective study, clinical trial, meta- analysis
Abstract Title : IDENTIFICATION OF FACTORS AFFECTING QUALITY OF LIFE
AMONG THALASSEMIA CHILDREN AT DORIS SYLVANUS PUBLIC
HOSPITAL, PALANGKARAYA, INDONESIA
Abstract Body : Background :

Improving supportive treatment in Thalassemia patients receiving blood

transfusion and iron chelation increases their life expectancies. Unfortunately,
this condition will make them face more social-culture problem. Little data
exists investigating the Health Related Quality of Life (HRQoL) of thalassemia
children. This study was aimed to identify factors affecting quality of life such
as demographic, age at diagnosis, clinical, blood transfusion, and chelation
characteristics among thalassemia children.

Material :

We conducted cross sectional study during March to April 2018, at Doris

Sylvanus Public Hospital. 35 patients receiving blood transfusion were enrolled
in this study. HRQoL was assessed using the PedsQL TM 4.0 Generic Core
Scale questionnaire, version 4.0, for children aged 5-18 years and scores were
categorized into either normal or impaired quality of life using age-specific
cut-offs. This tool measures 4 domains of life quality: physical, emotional,
social, and school function. Data were analyzed using SPSS version 16.

Results :
Girls and boys were almost equal. The median (IQR) age was 9 (5-18) years and
the median (IQR) age at diagnosis was 1 (0.4-12) years. The mean Hb level was
6.39±0.97 g/dL. 34.3% patients had low HRQoL, 57.14% had low physical
function and 54.3% had low school function. The mean HRQoL score was
80.58±12.35, and the mean physical, emotional, social and school function
scores were 79.25±18.75, 86±17.09, 90.71±11.32, and 64.65±18.61,
respectively. Facies Cooley were significantly correlate with HRQoL (P=0.020).
But, gender, age, residence, children and parental education, economic status,
age at diagnosis, hepatosplenomegaly, Hb level, blood transfusion and iron
chelation were not associated with HRQoL.

Conclusion :

One third children with thalassemia had low HRQoL and more than half of
subjects had low physical and school function. There were significant
differences between children having facies cooley and HRQoL. Therefore,
training program and psychosocial support should be more focus on children
having low life quality, especially patient with facies cooley.
PRESENTING AUTHOR INFORMATION
Email : ratih.dara.mutiara.dr@gmail.com
Name : Mutiara Dara Ratih
Affiliated Organization : Kalawa Atei Psychiatric Hospital
Phone : (62) 85250077509

AUTHOR INFORMATION
#1
First Name : NiMade
Last Name : Yuliari
Organization : Pediatric Department Doris Sylvanus Public Hospital Palangkaraya Indonesia

CO - AUTHOR INFORMATION
#1
First Name : Mutiara Dara
Last Name : Ratih
Organization : General Practitioner, Kalawa Atei Psychiatric Hospital, Bukit Rawi Indonesia
#2
First Name : Helena
Last Name : Jelita
Organization : Oral and Dental Department, Medicine Faculty of Palangkaraya University, Indonesia
#3
First Name : Donna Novina
Last Name : Kahanjak
Organization : Physiology Department, Medicine Faculty of Palangkaraya University, Indonesia
#4
First Name : Prabandari
Last Name : Kusumaningtyas
Organization : Pediatric Department, Doris Sylvanus Public Hospital, Palangkaraya, Indonesia