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Medicinal Chemistry - - Unit 8 - Week 5 https://onlinecourses-archive.nptel.ac.in/noc19_...

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Unit 8 - Week 5
Register for
Certification exam Assignment 5
The due date for submitting this assignment has passed.
Course As per our records you have not submitted this Due on 2019-03-06, 23:59 IST.
outline
assignment.

How to access 1) Tumours in an oxygen starved (hypoxic) environment are very difficult to 1 point
the portal kill

About IISER True


Pune
False
Pre-Requisite No, the answer is incorrect.
Assignment
Score: 0

Week 1 Accepted Answers:


True
Week 2
2) Once alkylated, guanine prefers the enol tautomer and is more likely to 1 point
base pair with thymine
Week 3

True
Week 4
False
Week 5
No, the answer is incorrect.
Quiz : Score: 0
Assignment 5
Accepted Answers:
Nucleic Acids True
as Drug Targets
Part-I 3) Shown below is guanine and the arrow indicates the nucleophilic group 1 point
that can get alkylated
Nucleic Acids
as Drug Targets
Part-II

Miscellaneous True
Drug Targets
False
Tutorial
09-Nucleic No, the answer is incorrect.
Acids and Score: 0
Related Topics
Accepted Answers:
Mechanisms in False
Biological © 2014 NPTEL - Privacy & Terms - Honor Code - FAQs -
Chemistry
A project of 4) Chain terminators have to be recognized
In association withby the DNA template by 1 point
Part-I interacting with a nucleic acid base on the template strand
Mechanisms in
Biological True
Funded by
Chemistry
False

1 of 4 Tuesday 11 June 2019 05:59 PM


Medicinal Chemistry - - Unit 8 - Week 5 https://onlinecourses-archive.nptel.ac.in/noc19_...

Part-II No, the answer is incorrect.


Powered by
Score: 0
Mechanisms in
Biological Accepted Answers:
Chemistry True
Part-III
5) Busulfan is an anticancer agent which causes interstrand cross-linking 1 point
Medicinal
Chemistry -
between thymine units
Week 5
Feedback True
False
Week 6
No, the answer is incorrect.
Week 7 Score: 0
Accepted Answers:
Week 8
False
Week 9 6) The hydrated ionic radius of sodium is greater than that of potassium 1 point

Week 10 True

Week 11 False

No, the answer is incorrect.


Week 12
Score: 0

Download Accepted Answers:


videos True

7) The compound shown below is Mitomycin C 1 point


TRANSCRIPTS

Interaction
Session
True
False

No, the answer is incorrect.


Score: 0
Accepted Answers:
True

8) Carbohydrates are polyhydroxy structures, many of which have the 1 point


general formula CnHn+1On

True
False

No, the answer is incorrect.


Score: 0
Accepted Answers:
False

9) The structure shown below is cis-Platin 1 point

True
False

No, the answer is incorrect.


Score: 0
Accepted Answers:
True

2 of 4 Tuesday 11 June 2019 05:59 PM


Medicinal Chemistry - - Unit 8 - Week 5 https://onlinecourses-archive.nptel.ac.in/noc19_...

This is a fill in the blank question – auto evaluated. Used when a word has to be
entered as the answer. Characters on the keyboard except ~ are allowed. The
match is an exact match and spelling mistakes or an extra space will also be
marked incorrect.

10)A _______________cuts the strands of DNA and prevents the enzyme DNA ligase
from repairing the damage

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) Chain cutter
(Type: String) Chaincutter

1 point

11)____________is the fungal equivalent of cholesterol and is an important


constituent of the fungal cell membrane.

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) Ergosterol

1 point

12)Fluoroquinolones are synthetic agents that inhibit the replication and


transcription of bacterial DNA by stabilizing the complex formed between DNA and
bacterial _____________________.

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) topoisomerase

1 point

13)________________drugs are compounds that contain planar or heteroaromatic


features which slip between the base-pair layers of the DNA double helix.

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) Intercalating
(Type: String) Intercalators
(Type: String) Intercalator

1 point

14)_________________is an example of a drug that binds to tubulin and prevents its


polymerization.

No, the answer is incorrect.

3 of 4 Tuesday 11 June 2019 05:59 PM


Medicinal Chemistry - - Unit 8 - Week 5 https://onlinecourses-archive.nptel.ac.in/noc19_...

Score: 0
Accepted Answers:
(Type: String) Colchicine

1 point

15)Valinomycin is selective for transport of ___________ions and disrupts ionic


equilibrium within cells

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) potassium

1 point

16)The structure shown below is D-_____________

No, the answer is incorrect.


Score: 0
Accepted Answers:
(Type: String) Ribose

1 point

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4 of 4 Tuesday 11 June 2019 05:59 PM

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