Medicinal Chemistry - - Unit 9 - Week 6 https://onlinecourses-archive.nptel.ac.in/noc19_...

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Unit 9 - Week 6
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Certification exam Assignment 6
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Course As per our records you have not submitted this Due on 2019-03-13, 23:59 IST.
outline
assignment.

How to access 1) For the carboxylic acid, the pKa = 4.6 and the pH = 6.2. Using the 1 point
the portal Henderson-Hasselbalch equation, 37.5% of is predicted to be ionized

About IISER True

Pune
False
Pre-Requisite No, the answer is incorrect.
Assignment
Score: 0

Week 1 Accepted Answers:

False
Week 2
2) Monoamine oxidase (MAO) is a flavoenzyme that catalyzes oxidation of 1 point
amines
Week 3

True
Week 4
False
Week 5
No, the answer is incorrect.
Week 6 Score: 0
Accepted Answers:
Pharmacokinetics
True
Part-I
3) Amides tend to be hydrolysed much faster than esters 1 point
Pharmacokinetics
Part-II
True
Drug
Metabolism False
Part-I
No, the answer is incorrect.
Drug Score: 0
Metabolism
Part-II
Accepted Answers:
False
Drug
Metabolism 4) Once a drug has been absorbed it is rapidly distributed around the blood 1 point
Part-III supply, then distributed more slowly to the various tissues and organs
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Drug
A project of
Metabolism True In association with
Part-IV
False
Tutorial
No, the answer is incorrect.
10-ADME Funded by
Score: 0

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Medicinal Chemistry - - Unit 9 - Week 6 https://onlinecourses-archive.nptel.ac.in/noc19_...

Quiz : Accepted Answers:

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Assignment 6 True

Week 6 5) The blood–brain barrier is an important barrier that drugs have to 1 point
Feedback form negotiate if they are to enter the brain

Week 7
True

Week 8 False

No, the answer is incorrect.

Week 9
Score: 0

Week 10 Accepted Answers:

True
Week 11
6) Pinocytosis , where the drug is engulfed by the cell membrane and a 1 point
membrane-bound vesicle is pinched off to carry the drug across the cell, occurs with
Week 12
highly hydrophobic drugs
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videos True
False
TRANSCRIPTS
No, the answer is incorrect.
Interaction Score: 0
Session
Accepted Answers:
False

This is a fill in the blank question – auto evaluated. Used when a word has to be
entered as the answer. Characters on the keyboard except ~ are allowed. The
match is an exact match and spelling mistakes or an extra space will also be
marked incorrect.

7) Some drugs bind to _________proteins in the blood

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) plasma

1 point

8) The vessels carrying blood around the body are called __________, veins, and
capillaries

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) arteries

1 point

9) Among phase II reactions, methylation and acetylation are important phase II

reactions which usually____________ the polarity of the drug

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) decrease

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Medicinal Chemistry - - Unit 9 - Week 6 https://onlinecourses-archive.nptel.ac.in/noc19_...

(Type: String) decreases

1 point

10)For a drug with a functional group of pKa value of 8.2, at pH ____________, the
molecule will be 50% ionized.

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: Numeric) 8.2

1 point

11)If the drug is too hydrophobic, it will be poorly soluble and will instead dissolve
in ________ globules, resulting in poor absorption.

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) fat

1 point

12)Primary and secondary amines are also oxidized to N-___________.

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) Oxides
(Type: String) oxide

1 point

13)Most phase II reactions are conjugation reactions catalysed by _____________

enzymes.

No, the answer is incorrect.

Score: 0
Accepted Answers:
(Type: String) transferase

1 point

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