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INTRODUCTION:-
Epidemiology is the basic science of preventive and social medicine. Modern epidemiology has
entered the most exciting phase of its evolution. By identifying risk factors of chronic disease,
evaluating treatment modalities and health services, it has provided new opportunities for
prevention, treatment, planning and improving the effectiveness and efficiency of health services.
DEFINITION:-
Epidemiology has been defined by John M. Last in 1988 as:-
"The study of the distribution and determinants of health
related states or events in specified population and the
application of this study to the control of health problems.”
Although there is no single definition to which all
epidemiologists subscribe, three components are common to
most of them. First, studies of disease frequency; second,
studies of the distribution; and third, studies of the
determinants. Each of these components confers an important
message.
1. Disease frequency
2.Distribution of disease
3.Determinants of disease
AIMS IN EPIDEMIOLOGY:-
According to the International Epidemiological Association,
epidemiology has three main aims:
A. to describe the distribution and magnitude of health and
disease problems in human populations
B. to identify aetiological factors (risk factors} in the
pathogenesis of disease;
C. to provide the data essential to the planning, implementation
and evaluation of services for the prevention, control and
treatment of disease and to the setting up of priorities among
those services.
in order to fulfil these aims, three rather different classes of
epidemiological studies may be mentioned:
1. Descriptive studies,
2. Analytical studies,
3. Experimental or intervention studies.
The ultimate aim of epidemiology is to lead to effective action:
A. to eliminate or reduce the health problem or its
consequences;
B. to promote the health and well-being of society as a whole.
Tools of measurement
The epidemiologist usually expresses disease magnitude as a
rate, ratio or proportion. A clear understanding of the term is
1. RATE:-
A rate measures the occurrence of some particular event
(development of disease or the occurrence of death) in a
population during a given time period. An example of a typical
rate is the death rate.
A rate comprises the following elements - numerator,
denominator, time specification and multiplier.
The various categories of rates are:
(1) Crude rates
(2) Specific rates
(3) Standardized rates
2. RATIO:-
Another measure of disease frequency is a ratio. It expresses a
relation in size between two random quantities. The numerator
is not a component of the denominator.
3. PROPORTION
A proportion is a ratio which indicates the relation in magnitude
of a part of the whole. The numerator is always included in the
denominator. A proportion is usually expressed as a
percentage.
MEASUREMENT OF MORTALITY
MEASUREMENT OF MORBIDITY
Morbidity has been defined as "any departure, subjective or
objective, from a state of physiological well-being"
The WHO Expert Committee on Health Statistics noted in its 6th
Report (17) that morbidity could be measured in terms of 3
units (a) persons who were ill; (b) the illnesses (periods or spells
of illness) that these persons experienced; and (c) the duration
(days, weeks, etc.) of these illnesses.
INCIDENCE
Incidence rate is defined as "the number of NEW cases
occurring in a defined population during a specified period of
time".
USES OF INCIDENCE RATE
The incidence rate, as a health status indicator, is useful for
taking action
(a) To control disease, and
(b) For research into aetiology and pathogenesis, distribution of
diseases, and efficacy of preventive and therapeutic measures.
PREVALENCE
The term "disease prevalence" refers specifically to all current
cases (old and new) existing at a given point in time, or over a
period of time in a given population. A broader definition of
prevalence is as follows: "the total number of all individuals
who have an attribute or disease at a particular time (or during
a particular period) divided by the population at risk of having
the attribute or disease at this point in time or midway through
the period". Although referred to as a rate, prevalence rate is
really a ratio.
Prevalence is of two types:
(a) Point prevalence
(b) Period prevalence
Uses of prevalence
(a) Prevalence helps to estimate the magnitude of health/
disease problems in the community, and identify potential high-
risk populations
(b) Prevalence rates are especially useful for administrative and
planning purposes, e.g., hospital beds, manpower needs,
rehabilitation facilities, etc.
TIME CONTENT
SUMMERIZATION:
Definition
Location
Structure
Blood supply
Nerve Supply
Bile production
Function of liver
CONCLUSION:
Liver is the organ of most importance in our body. It involves in many important functions of our body which are essential for our living.